{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T06:39:55Z","timestamp":1767595195048,"version":"3.48.0"},"reference-count":17,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T00:00:00Z","timestamp":1767571200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the clinical characteristics and postoperative speech development in children with incomplete partition type III (IPIII) cochlear malformation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective analysis was conducted on 6 patients (12 ears) diagnosed with IPIII cochlear malformation, all patients underwent preoperative high-resolution CT (HRCT), middle ear and cranial MRI, and audiological evaluations. Intraoperative cochlear imaging was performed to confirm electrode placement, there was also 1 types of comparison: IP III patients with matched CI patients without inner ear malformations, questionnaires were used to evaluate auditory and speech perception<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>All 6 patients were male, with 3 undergoing bilateral cochlear implantation and 3 undergoing unilateral implantation (1 left, 2 right). The surgical age ranged from 8 months to 12 years, with a median age of 17 months. HRCT findings in all 12 ears (100%) showed a grossly normal cochlear shape with bony cochlear partitions present but an absent modiolus. Ten ears (10\/12; 83.3%) exhibited enlarged internal auditory canals (6.13\u2009\u00b1\u20090.395\u2005mm), 9 ears (9\/12; 75%) had profound sensorineural hearing loss, 4 ears (4\/12; 33.3%) showed significant vestibular dilation with a cystic appearance, and 4 ears (4\/12; 33.3%) had enlarged vestibular aqueducts. All patients had normal auditory nerve development (100%). intraoperative neural response telemetry (NRT) responses were successfully elicited in all cases, and all patients experienced gusher phenomenon (6\/6; 100%). Intraoperative cochlear imaging preliminarily confirmed electrode placement. Follow-up ranged from 3 months to 1 year, with preoperative CAP scores 0.83\u2009\u00b1\u20090.41 and postoperative CAP scores 6\u2009\u00b1\u20091.55, p&amp;lt;0.05. In Speech Intelligibility Rating (SIR) questionnaires, CI patients without inner ear malformations outperformed IP III patients, while there was no significant difference in other questionnaires.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>IPIII cochlear malformation is more common in male patients and is often associated with profound to severe sensorineural hearing loss. Cochlear implantation for IP-III malformation leads to significant auditory-speech improvement in early stage and can result in varying degrees of oral competence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fped.2025.1682673","type":"journal-article","created":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T06:37:37Z","timestamp":1767595057000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical portrait of cochlear implantation in patients with incomplete partition type-III malformation"],"prefix":"10.3389","volume":"13","author":[{"given":"Peng","family":"Zhu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kun","family":"Ni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao yan","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zheng nong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,1,5]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.anl.2017.02.006","article-title":"Incomplete partition type III: a rare and difficult cochlear implant surgical indication","volume":"45","author":"Sennaro\u011flu","year":"2018","journal-title":"Auris Nasus Larynx"},{"key":"B2","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1097\/MAO.0000000000000343","article-title":"De novo large genomic deletions involving POU3F4 in incomplete partition type III inner ear anomaly in east Asian populations and implications for genetic counseling","volume":"36","author":"Choi","year":"2015","journal-title":"Otol Neurotol"},{"key":"B3","doi-asserted-by":"publisher","first-page":"2230","DOI":"10.1097\/00005537-200212000-00019","article-title":"A new classification for cochleovestibular malformations","volume":"112","author":"Sennaroglu","year":"2002","journal-title":"Laryngoscope"},{"key":"B4","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1126\/science.7839145","article-title":"Association between X-linked mixed deafness and mutations in the POU domain gene POU3F4","volume":"267","author":"de Kok","year":"1995","journal-title":"Science"},{"key":"B5","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1080\/14670100.2016.1180018","article-title":"Cochlear implantation in X-linked deafness -how to manage the surgical challenges","volume":"17","author":"Saeed","year":"2016","journal-title":"Cochlear Implants Int"},{"key":"B6","doi-asserted-by":"publisher","first-page":"1689","DOI":"10.1016\/j.ijporl.2015.07.027","article-title":"Surgical techniques and outcomes of cochlear implantation in patients with radiographic findings consistent with X-linked deafness","volume":"79","author":"Cosetti","year":"2015","journal-title":"Int. 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