{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T00:08:43Z","timestamp":1789776523119,"version":"4.0.1"},"reference-count":41,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T00:00:00Z","timestamp":1767571200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate possible sleep disturbances in children with juvenile idiopathic arthritis (JIA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This case-control investigation evaluated 48 JIA patients vs. 90 healthy controls through comprehensive clinical assessments. Disease activity was quantified using the Juvenile Arthritis Disease Activity Score (JADAS-27), while health-related quality of life was measured with the Child Health Questionnaire (CHQ-PF28). Pain intensity was assessed through dual Methods: Visual Analog Scale (VAS) and Wong Baker Faces Scale. Fatigue levels were evaluated via the Pediatric Quality of Life Inventory Multidimensional Fatigue Scale (PedsQL-MFS), and sleep quality was analyzed using both the Children's Sleep Habits Questionnaire (CSHQ) and Sleep Disturbance Scale for Children (SDSC). All statistical analyses were conducted in SPSS 26.0, employing independent\n                      <jats:italic>t<\/jats:italic>\n                      -tests for intergroup comparisons and Spearman correlation analysis for variable relationships.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The incidence of sleep disturbance was significantly higher in the JIA group (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&amp;lt;\u20090.01). CSHQ assessments reveal abnormal total scores and six subdomains (sleep duration, daytime sleepiness, etc.; all\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&amp;lt;\u20090.05), with specific correlations: total scores link to disease activity (JADAS-27\/AJC;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.021\u20130.05), shortened sleep duration strongly associates with ESR\/functional status (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.002\/0.006), and daytime sleepiness connects to physician global assessments (PGA\/PGE;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.017\u20130.029). SDSC evaluations indicate abnormalities in four domains (all\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&amp;lt;\u20090.05), notably: night hyperhidrosis correlates with disease activity markers (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.032\u20130.039), excessive sleepiness associates with fatigue\/functional impairment (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.014\/0.038), and arousal disorders relate to medication use (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.029).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>JIA patients show significantly higher rates of sleep disorders compared to healthy children, primarily due to disease activity, functional impairment, and medication effects.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fped.2025.1703948","type":"journal-article","created":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T06:36:46Z","timestamp":1767595006000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["The association between Children's sleep quality and juvenile idiopathic 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