{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T03:05:03Z","timestamp":1767236703165,"version":"3.45.0"},"reference-count":21,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T00:00:00Z","timestamp":1762992000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"abstract":"<jats:p>Primary segmental volvulus (PSV) is a rare cause of acute abdomen in infants. It is characterized by a form of strangulated intestinal obstruction requiring prompt diagnosis and surgical intervention. This study aimed to report a case of PSV in an infant, which was managed successfully through early recognition, close clinical monitoring, and timely surgical treatment. Although both blood and ascitic fluid cultures were negative postoperatively, metagenomic next-generation sequencing (mNGS) identified the same pathogen in both specimens, enabling targeted antibiotic therapy. This case highlights the importance of including PSV in the differential diagnosis of infants presenting with unexplained abdominal distension and bilious vomiting, particularly when accompanied by anemia. Additionally, the elevated level of the coagulation system biomarker thrombin\u2013antithrombin complex (TAT) may serve as a useful marker for monitoring coagulation status in the perioperative period. The integration of TAT assessment and mNGS-based pathogen identification provides a novel framework for individualized perioperative management in PSV.<\/jats:p>","DOI":"10.3389\/fped.2025.1707716","type":"journal-article","created":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T06:30:59Z","timestamp":1763015459000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Case Report: Primary segmental volvulus in an infant"],"prefix":"10.3389","volume":"13","author":[{"given":"Wenya","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoping","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weilu","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,11,13]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"146","DOI":"10.3389\/fped.2019.00146","article-title":"Primary segmental volvulus of small intestine: surgical perspectives according to age at diagnosis","volume":"7","author":"Kim","year":"2019","journal-title":"Front Pediatr"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1375","DOI":"10.1016\/j.jpedsurg.2020.08.029","article-title":"Comparison of total midgut volvulus and segmental volvulus in neonates","volume":"56","author":"Chung","year":"2021","journal-title":"J Pediatr Surg"},{"key":"B3","doi-asserted-by":"publisher","first-page":"e25","DOI":"10.1016\/j.jpedsurg.2008.11.037","article-title":"Mesenteric lipoblastoma presenting as a segmental volvulus","volume":"44","author":"Yu","year":"2009","journal-title":"J Pediatr Surg"},{"key":"B4","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1111\/apa.16167","article-title":"Distinguishing outcomes of neonatal intestinal volvulus: review of our experience over the last 20 years","volume":"111","author":"Maya-Enero","year":"2022","journal-title":"Acta Paediatr"},{"key":"B5","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1016\/j.jpedsurg.2008.10.090","article-title":"Late-onset volvulus without malrotation in preterm infants","volume":"44","author":"Drewett","year":"2009","journal-title":"J Pediatr Surg"},{"key":"B6","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1016\/j.jss.2014.08.043","article-title":"Volvulus without malposition\u2013a single-center experience","volume":"193","author":"Kargl","year":"2015","journal-title":"J Surg Res"},{"key":"B7","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.1016\/j.jpedsurg.2013.05.011","article-title":"Fetal primary small bowel volvulus in a child without intestinal malrotation","volume":"48","author":"Chung","year":"2013","journal-title":"J Pediatr Surg"},{"key":"B8","doi-asserted-by":"publisher","first-page":"1339","DOI":"10.1016\/0022-3468(94)90111-2","article-title":"Mesenteric defects as a cause of intestinal volvulus without malrotation and as the possible primary etiology of intestinal atresia","volume":"29","author":"Black","year":"1994","journal-title":"J Pediatr Surg"},{"key":"B9","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1186\/s12887-014-0287-2","article-title":"Late-onset volvulus without malrotation in extremely preterm infants\u2013a case-control-study","volume":"14","author":"Maas","year":"2014","journal-title":"BMC Pediatr"},{"key":"B10","doi-asserted-by":"publisher","first-page":"508","DOI":"10.12669\/pjms.342.14473","article-title":"Planned second look laparotomy in neonatal volvulus - 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