{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T03:28:21Z","timestamp":1793330901993,"version":"4.5.0"},"reference-count":23,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T00:00:00Z","timestamp":1776902400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"abstract":"<jats:p>Febrile Ulceronecrotic Mucha- Habermann Disease (FUMHD) is a rare and severe specialized type of Pityriasis Lichenoides Et Varioliformis Acuta (PLEVA). It is characterized by rapid onset of painful necrotic skin lesions and systemic symptoms. The diagnosis of FUMHD is complex and is easily misdiagnosed in the early stages. Despite the increasing number of reports of FUMHD in recent years, it is still uncommon in preschool (3\u20136 years) children. We here report a 3-year-9-month-old girl of FUMHD from China, cured through combined antibiotics, intravenous immunoglobulin, methotrexate, and prednisone. Besides, a literature review was conducted to synthesize the key findings of preschool FUMHD cases.<\/jats:p>","DOI":"10.3389\/fped.2026.1762372","type":"journal-article","created":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T05:38:21Z","timestamp":1776922701000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Febrile ulceronecrotic Mucha-Habermann disease: a case report and literature review in preschool-aged children"],"prefix":"10.3389","volume":"14","author":[{"given":"Jun","family":"Luo","sequence":"first","affiliation":[{"name":"Ministry of Basic Medical Education, Dazhou Vocational College of Chinese Medicine","place":["Dazhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueshuang","family":"Liu","sequence":"additional","affiliation":[{"name":"Ministry of Basic Medical Education, Dazhou Vocational College of Chinese Medicine","place":["Dazhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuan","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, Maternal and Child Health Hospital of Hubei Province","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Wang","sequence":"additional","affiliation":[{"name":"Ministry of Basic Medical Education, Dazhou Vocational College of Chinese Medicine","place":["Dazhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenshuang","family":"Wei","sequence":"additional","affiliation":[{"name":"Ministry of Basic Medical Education, Dazhou Vocational College of Chinese Medicine","place":["Dazhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,4,23]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"9492","DOI":"10.4081\/dr.2022.9492","article-title":"Mortality risk factors in febrile ulceronecrotic Mucha- Habermann disease: a systematic review of therapeutic outcomes and complications","volume":"14","author":"Tasouli-Drakou","year":"2022","journal-title":"Dermatol Rep"},{"key":"B2","doi-asserted-by":"publisher","first-page":"adv4806","DOI":"10.2340\/actadv.v103.4806","article-title":"Febrile ulceronecrotic Mucha-Habermann disease: a case report and review of literature in the paediatric population","volume":"103","author":"Liu","year":"2023","journal-title":"Acta Derm Venereol"},{"key":"B3","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1111\/j.1525-1470.2011.01608.x","article-title":"Febrile ulceronecrotic mucha-habermann disease (pityriasis lichenoides et varioliformis acuta fulminans) presenting as stevens-johnson syndrome","volume":"29","author":"Kaufman","year":"2012","journal-title":"Pediatr Dermatol"},{"key":"B4","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1111\/ijd.13195","article-title":"Febrile ulceronecrotic Mucha-Habermann disease: proposed diagnostic criteria and therapeutic evaluation","volume":"55","author":"Nofal","year":"2016","journal-title":"Int J Dermatol"},{"key":"B5","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1159\/000246385","article-title":"Febrile ulceronecrotic Mucha-Habermann disease: a case report and review of the literature","volume":"192","author":"Su\u00e1rez","year":"1996","journal-title":"Dermatology"},{"key":"B6","doi-asserted-by":"publisher","first-page":"350","DOI":"10.2340\/00015555-0441","article-title":"Febrile ulceronecrotic Mucha-Habermann disease: a case report and review of the literature","volume":"88","author":"Sotiriou","year":"2008","journal-title":"Acta Derm Venereol"},{"key":"B7","doi-asserted-by":"publisher","first-page":"690","DOI":"10.21037\/tp-23-520","article-title":"A case report of febrile ulceronecrotic Mucha-Habermann disease","volume":"13","author":"Ma","year":"2024","journal-title":"Transl Pediatr"},{"key":"B8","first-page":"481","article-title":"Hyperthermic ulcero-necrotic parapsoriasis. 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