{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T15:23:58Z","timestamp":1791559438552,"version":"4.3.4"},"reference-count":19,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T00:00:00Z","timestamp":1788393600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"abstract":"<jats:p>Kasabach\u2013Merritt phenomenon (KMP) is a life-threatening consumptive coagulopathy in children with kaposiform hemangioendothelioma (KHE) or tufted angioma. Until now, there has been no well-accepted treatment regimen in the literature. A pelvic KHE is very rare and its deep anatomical location and invasive growth pattern toward adjacent vital organs pose significant management challenges. Here, we report a 10-month-old girl presenting with KMP secondary to a pelvic KHE. Initial systemic therapy with sirolimus and corticosteroids failed to control her KMP. Transcatheter arterial embolization was performed using polyvinyl alcohol particles and coils. After embolization, the tumor\u2019s blood supply decreased significantly and the patient\u2019s platelet counts and coagulation markers returned to normal in 3 days. At the 2-year follow-up, her coagulation function remained normal. The perineal cutaneous rash resolved and the tumor\u2019s volume decreased substantially. This case demonstrates that transarterial embolization can be an effective therapeutic choice when systemic treatment has failed.<\/jats:p>","DOI":"10.3389\/fped.2026.1821994","type":"journal-article","created":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T06:40:19Z","timestamp":1788417619000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Transcatheter embolization as a rescue therapy for refractory pelvic kaposiform hemangioendothelioma with Kasabachi\u2013Merritt phenomenon: a case report"],"prefix":"10.3389","volume":"14","author":[{"given":"Yi","family":"Xiong","sequence":"first","affiliation":[{"name":"Hemangioma and Vascular Anomaly Center, Capital Center for Children\u2019s Health, Capital Institute of Pediatrics, Capital Medical University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Di","sequence":"additional","affiliation":[{"name":"Hemangioma and Vascular Anomaly Center, Capital Center for Children\u2019s Health, Capital Institute of Pediatrics, Capital Medical University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanlin","family":"Li","sequence":"additional","affiliation":[{"name":"Hemangioma and Vascular Anomaly Center, Capital Center for Children\u2019s Health, Capital Institute of Pediatrics, Capital Medical University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiajie","family":"Cao","sequence":"additional","affiliation":[{"name":"Hemangioma and Vascular Anomaly Center, Capital Center for Children\u2019s Health, Capital Institute of Pediatrics, Capital Medical University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenghao","family":"Chen","sequence":"additional","affiliation":[{"name":"Hemangioma and Vascular Anomaly Center, Capital Center for Children\u2019s Health, Capital Institute of Pediatrics, Capital Medical University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Shen","sequence":"additional","affiliation":[{"name":"Hemangioma and Vascular Anomaly Center, Capital Center for Children\u2019s Health, Capital Institute of Pediatrics, Capital Medical University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,3]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"e30779","DOI":"10.1002\/pbc.30779","article-title":"Treatment practices and response in kaposiform hemangioendothelioma: a multicenter cohort 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