{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T06:04:32Z","timestamp":1789452272528,"version":"build-2803163510"},"reference-count":12,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T00:00:00Z","timestamp":1789430400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"abstract":"<jats:p>Fibroepithelial polyps are benign tumours that usually arise from cutaneous or mucosal surfaces. In children they most commonly involve the skin, oral cavity, and genitourinary tract, whereas endobronchial localization is exceptionally rare. We report the case of a 9-year-old girl with persistent biphasic wheezing, cough and dyspnoea on exertion despite appropriate asthma-directed treatment. High-resolution computed tomography of the chest revealed an endobronchial lesion associated with distal bronchiectatic changes, and bronchoscopy confirmed the presence of a protruding endobronchial polyp. The lesion was completely removed endoscopically, and histopathological and immunohistochemical examination confirmed the diagnosis of a benign fibroepithelial polyp. Following removal, the respiratory symptoms resolved completely, with substantial regression of the bronchiectatic changes at six-month follow-up. This case highlights the importance of considering structural airway obstruction in children with persistent or biphasic wheezing that fails to respond to appropriate asthma therapy.<\/jats:p>","DOI":"10.3389\/fped.2026.1938806","type":"journal-article","created":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T05:35:36Z","timestamp":1789450536000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Endobronchial fibroepithelial polyp presenting as persistent wheezing in a 9-year-old girl: a case report"],"prefix":"10.3389","volume":"14","author":[{"given":"Veronica","family":"Ferasin","sequence":"first","affiliation":[{"name":"Women\u2019s and Children\u2019s Health Department - SDB, University of Padova","place":["Padova, Italy"]},{"name":"Unit of Pediatric Allergy and Respiratory Medicine, University Hospital of Padova","place":["Padova, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Sansone","sequence":"additional","affiliation":[{"name":"Unit of Pediatrics, Rovigo Hospital","place":["Rovigo, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefania","family":"Zanconato","sequence":"additional","affiliation":[{"name":"Unit of Pediatric Allergy and Respiratory Medicine, University Hospital of Padova","place":["Padova, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cesare","family":"Cutrone","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Azienda Ospedale Universit\u00e0 di Padova","place":["Padova, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianna","family":"Sari","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Azienda Ospedale Universit\u00e0 di Padova","place":["Padova, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina Agnese","family":"Ferraro","sequence":"additional","affiliation":[{"name":"Women\u2019s and Children\u2019s Health Department - SDB, University of Padova","place":["Padova, Italy"]},{"name":"Unit of Pediatric Allergy and Respiratory Medicine, University Hospital of Padova","place":["Padova, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Carraro","sequence":"additional","affiliation":[{"name":"Women\u2019s and Children\u2019s Health Department - SDB, University of Padova","place":["Padova, Italy"]},{"name":"Unit of Pediatric Allergy and Respiratory Medicine, University Hospital of Padova","place":["Padova, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,15]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"E121","DOI":"10.1002\/ppul.22987","article-title":"Characteristics of endobronchial primitive tumors in children","volume":"49","author":"Eyssartier","year":"2014","journal-title":"Pediatr Pulmonol"},{"key":"B2","doi-asserted-by":"publisher","first-page":"2074970","DOI":"10.1155\/2016\/2074970","article-title":"Endobronchial carcinoid and concurrent carcinoid syndrome in an adolescent female","author":"Cogen","year":"2016","journal-title":"Case Rep Pediatr"},{"key":"B3","doi-asserted-by":"publisher","first-page":"e55","DOI":"10.1097\/LBR.0000000000000814","article-title":"Fibroepithelial polyp as a rare cause of bronchial obstruction in a child","volume":"29","author":"Thimmesch","year":"2022","journal-title":"J Bronchology Interv Pulmonol"},{"key":"B4","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/S2213-2600(17)30472-1","article-title":"Standardisation of lung function test interpretation: global lung function initiative","volume":"6","author":"Stanojevic","year":"2018","journal-title":"Lancet Respir Med"},{"key":"B5","doi-asserted-by":"publisher","first-page":"30","DOI":"10.5409\/wjcp.v4.i2.30","article-title":"Endobronchial tumor in children: unusual finding in recurrent pneumonia, report of three cases","volume":"4","author":"Madafferi","year":"2015","journal-title":"World J Clin Pediatr"},{"key":"B6","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1177\/000348940111000112","article-title":"Endobronchial tumors in children: an uncommon clinical entity","volume":"110","author":"Scott","year":"2001","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"B7","year":"2025"},{"key":"B8","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.lungcan.2019.04.016","article-title":"Endobronchial and surgical treatment of pulmonary carcinoid tumors: a systematic literature review","volume":"134","author":"Reuling","year":"2019","journal-title":"Lung Cancer"},{"key":"B9","doi-asserted-by":"publisher","first-page":"5269728","DOI":"10.1155\/2019\/5269728","article-title":"Bronchoscopic treatment of benign endoluminal lung tumors","author":"Dalar","year":"2019","journal-title":"Can Respir J"},{"key":"B10","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1097\/CPM.0b013e31821823ad","article-title":"Therapeutic relief of benign endobronchial tumors","volume":"18","author":"Bellinger","year":"2011","journal-title":"Clin Pulm Med"},{"key":"B11","doi-asserted-by":"publisher","first-page":"866","DOI":"10.1016\/S0140-6736(18)31554-X","article-title":"Bronchiectasis in children: diagnosis and treatment","volume":"392","author":"Chang","year":"","journal-title":"Lancet"},{"key":"B12","doi-asserted-by":"publisher","first-page":"2002990","DOI":"10.1183\/13993003.02990-2020","article-title":"European Respiratory society guidelines for the management of children and adolescents with bronchiectasis","volume":"58","author":"Chang","year":"2021","journal-title":"Eur Respir J"}],"container-title":["Frontiers in Pediatrics"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fped.2026.1938806\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T05:35:37Z","timestamp":1789450537000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fped.2026.1938806\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,15]]},"references-count":12,"alternative-id":["10.3389\/fped.2026.1938806"],"URL":"https:\/\/doi.org\/10.3389\/fped.2026.1938806","relation":{},"ISSN":["2296-2360"],"issn-type":[{"value":"2296-2360","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,15]]},"article-number":"1938806"}}