{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T06:11:50Z","timestamp":1790143910772,"version":"4.0.1"},"reference-count":13,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T00:00:00Z","timestamp":1790121600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"abstract":"\n Background<\/jats:title>\n Detailed clinical descriptions of paediatric atopic dermatitis from southern China are scarce; available Chinese data are largely modelled burden estimates or laboratory series of allergen sensitisation.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n This single-centre cross-sectional study included 47 children and adolescents aged 3.6\u201319.0\u2005years meeting the UK Working Party criteria at a tertiary dermatology clinic in Fuzhou, Fujian Province, China. Triggers, comorbidities and family history were extracted from routine records and are reported as recorded histories, not as verified diagnoses or as prevalence estimates. Severity was assessed by body surface area (BSA), a score the assessing dermatologist reports having assigned as a global clinical impression rather than computed from the SCORing Atopic Dermatitis (SCORAD) components, as well as the Patient-Oriented Eczema Measure (POEM) and the Children\u2019s Dermatology Life Quality Index. The two source workbooks were audited for copying artefacts, and every value flagged by the audit was checked against the original clinic record. Proportions are reported with Wilson 95% confidence intervals.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Median age was 11.0\u2005years (interquartile range 6.0\u201313.5\u2005years). House dust mite was the most frequently reported trigger (27\/47, 57.4%), followed by seafood or crustaceans (40.4%) and a damp environment (21.3%); most participants reported more than one trigger. No specific IgE or skin prick testing was performed, so these are reported triggers only and not sensitisations. A family history of allergic disease was recorded in 95.7% (95% CI 85.8\u201398.8) and allergic rhinitis in 70.2% (56.0\u201381.3); the rhinitis figure is partly constitutive of the enrolment criteria, and the family history figure reflects a deliberately broad definition. Recorded asthma was rare (1\/44, 2.3%), a record-keeping observation rather than a prevalence estimate. Seventeen values in 10 records were residues of copying between the workbooks and were corrected against the original records. BSA and the severity score correlated within each batch (\n \u03c1<\/jats:italic>\n \u2009=\u20090.71 and 0.58) but not when pooled (\n \u03c1<\/jats:italic>\n \u2009=\u20090.03), whereas POEM correlated with BSA throughout; severity is therefore reported by batch.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n House dust mite was the most frequently reported trigger, a recorded history of allergic rhinitis was common, and the disease was predominantly moderate within each batch. Every figure is a recorded-history count reflecting one clinic's ascertainment and its enrolment criteria, not a population prevalence estimate. These are preliminary observations requiring confirmation in larger, prospectively defined, multi-centre cohorts.<\/jats:p>\n <\/jats:sec>","DOI":"10.3389\/fped.2026.1946416","type":"journal-article","created":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T05:54:50Z","timestamp":1790142890000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical profile, reported triggers, and comorbidity pattern in children and adolescents with atopic dermatitis: a cross-sectional study from Fujian, China"],"prefix":"10.3389","volume":"14","author":[{"given":"Wenping","family":"Ma","sequence":"first","affiliation":[{"name":"Dermatology Department, Fuzhou First General Hospital Affiliated with Fujian Medical University","place":["Fuzhou, Fujian, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Liu","sequence":"additional","affiliation":[{"name":"Clinical Laboratory, Fuzhou First General Hospital Affiliated with Fujian Medical University","place":["Fuzhou, Fujian, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Li","sequence":"additional","affiliation":[{"name":"Dermatology Department, Fuzhou First General Hospital Affiliated with Fujian Medical University","place":["Fuzhou, Fujian, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziping","family":"Zhang","sequence":"additional","affiliation":[{"name":"Dermatology Department, The First Affiliated Hospital of Fujian Medical University","place":["Fuzhou, Fujian, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,23]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"e14271","DOI":"10.1111\/pai.14271","article-title":"Trends in atopic dermatitis prevalence among the Chinese population (1990\u20132021) with projections for 2022\u20132030","volume":"35","author":"Zhou","year":"2024","journal-title":"Pediatr Allergy Immunol"},{"key":"B2","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1111\/ijd.70085","article-title":"Burden of atopic dermatitis in China and its provinces, 1990\u20132021: a global burden of disease 2021 analysis","volume":"64","author":"Zhao","year":"2025","journal-title":"Int J Dermatol"},{"key":"B3","doi-asserted-by":"publisher","first-page":"1840","DOI":"10.1016\/j.jaip.2020.02.022","article-title":"Endophenotypic variations of atopic dermatitis by age, race, and ethnicity","volume":"8","author":"Nomura","year":"2020","journal-title":"J Allergy Clin Immunol Pract"},{"key":"B4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1159\/000551204","article-title":"Shifting patterns of allergen sensitization in 8,797 children with atopic dermatitis during the COVID-19 restriction measures: a retrospective study from Hangzhou, China","author":"Qiu","year":"2026","journal-title":"Int Arch Allergy Immunol"},{"key":"B5","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1111\/j.1365-2133.1994.tb08530.x","article-title":"The U.K. Working party\u2019s diagnostic criteria for atopic dermatitis. 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