{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T05:52:07Z","timestamp":1791525127151,"version":"4.3.4"},"reference-count":37,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T00:00:00Z","timestamp":1791504000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pediatr."],"abstract":"\n Background<\/jats:title>\n Children with cerebral palsy (CP) are at high risk of pulmonary infection with multidrug-resistant organisms (MDROs) owing to recurrent infections, prolonged hospitalization, and repeated antibiotic exposure. Bacteriophage (phage) therapy has emerged as a promising alternative for infections refractory to conventional antibiotics; however, its application in children with CP complicated by multidrug-resistant pneumonia has rarely been reported, and corresponding nursing experience remains scarce.<\/jats:p>\n <\/jats:sec>\n \n Case presentation<\/jats:title>\n \n This report describes the nursing care of a 2-year-and-4-month-old boy with CP, secondary epilepsy, and severe pneumonia caused by carbapenem-resistant\n Acinetobacter baumannii<\/jats:italic>\n (CRAB), carbapenem-resistant\n Klebsiella pneumoniae<\/jats:italic>\n (CRKP), and\n Staphylococcus aureus<\/jats:italic>\n (discharge diagnosis: methicillin-resistant\n S. aureus<\/jats:italic>\n infection), in whom conventional antibiotic therapy had failed. After comprehensive eligibility assessment, percutaneous endoscopic gastrostomy (PEG)-based nutritional optimization, and written informed consent, the child received a pre-planned 3-day course of nebulized phage cocktail therapy. Nursing care integrated standardized phage aerosol administration, staged enteral nutritional support, and family-centered health education. After treatment,\n A. baumannii<\/jats:italic>\n was eradicated from bronchoalveolar lavage fluid, and subsequent\n A. baumannii<\/jats:italic>\n isolates were susceptible to imipenem and meropenem (MIC\u2009\u2264\u20090.25\u2005\u03bcg\/mL, versus \u226516\u2005\u03bcg\/mL before therapy); CRKP was not re-isolated, and later\n S. aureus<\/jats:italic>\n isolates were oxacillin-susceptible. Body temperature normalized, peripheral oxygen saturation remained stable without supplemental oxygen, and inflammatory markers decreased markedly. Body weight increased from 13.40\u2005kg to 14.35\u2005kg, and the nutritional risk score (STAMP) decreased from 5 (high risk) to 3. The child was discharged after 58 days of hospitalization.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n This case suggests that a structured nursing pathway embedding nebulized phage therapy is feasible and effective in medically complex children and may inform the care of similar pediatric cases.<\/jats:p>\n <\/jats:sec>","DOI":"10.3389\/fped.2026.1955901","type":"journal-article","created":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T05:34:28Z","timestamp":1791524068000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Nursing care of a child with cerebral palsy and multidrug-resistant bacterial pneumonia treated with bacteriophage therapy: a case report"],"prefix":"10.3389","volume":"14","author":[{"given":"Lu","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Infectious Diseases, Shanghai Children's Hospital","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunyan","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Infectious Diseases, Shanghai Children's Hospital","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiwen","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Infectious Diseases, Shanghai Children's Hospital","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Infectious Diseases, Shanghai Children's Hospital","place":["Shanghai, 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