{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T18:38:27Z","timestamp":1793039907611,"version":"4.5.0"},"reference-count":58,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,5,6]],"date-time":"2020-05-06T00:00:00Z","timestamp":1588723200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pharmacol."],"DOI":"10.3389\/fphar.2020.00542","type":"journal-article","created":{"date-parts":[[2020,5,6]],"date-time":"2020-05-06T13:35:40Z","timestamp":1588772140000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":42,"title":["Pulmonary Rehabilitation and Asthma"],"prefix":"10.3389","volume":"11","author":[{"given":"Elisabetta","family":"Zampogna","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Zappa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Spanevello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dina","family":"Visca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2020,5,6]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1183\/09031936.04.00074703","article-title":"Dyspnoea at rest and at the end of different","volume":"24","author":"Barreiro","year":"2004","journal-title":"Eur. Respir. J."},{"key":"B2","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1164\/rccm.200611-1717OC","article-title":"Overweight, obesity, and incident asthma: a meta-analysis of prospective epidemiologic studies","volume":"175","author":"Beuther","year":"2007","journal-title":"Am. J. Respir. Crit. CareMed."},{"key":"B3","doi-asserted-by":"publisher","first-page":"644","DOI":"10.1111\/j.1600-0838.2009.00985.x","article-title":"An index for breathlessness and leg fatigue","volume":"20","author":"Borg","year":"2010","journal-title":"Scand. J. Med. Sci. Sports"},{"key":"B4","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1378\/chest.13-1796","article-title":"Mediator effect of depressive symptoms on the association between BMI and asthma control in adults","volume":"146","author":"Boudreau","year":"2014","journal-title":"Chest"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-013856","article-title":"Physical activity and incident asthma in adults: the HUNT Study, Norway","volume":"6","author":"Brumpton","year":"2016","journal-title":"BMJ Open"},{"key":"B6","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/S2213-2600(17)30474-5","article-title":"Physiotherapy breathing retraining for asthma: a randomized controlled trial","volume":"6","author":"Bruton","year":"2018","journal-title":"Lancet Respir. Med."},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD001116.pub4","article-title":"Physical training for asthma","volume":"30","author":"Carson","year":"2013","journal-title":"Cochrane Database Syst. Rev."},{"key":"B8","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1053\/rmed.2000.0968","article-title":"Psychological disorder in asthma is associated with poor control and poor adherence to inhaled steroids","volume":"95","author":"Cluley","year":"2001","journal-title":"Respir. Med."},{"key":"B9","doi-asserted-by":"publisher","first-page":"1186","DOI":"10.1080\/02640414.2017.1364402","article-title":"Effects of an Unsupervised Pedometer-Based Physical Activity Program on Daily Steps of Adults With Moderate to Severe Asthma: A Randomized Controlled Trial","volume":"36","author":"Coelho","year":"2018","journal-title":"J. Sports Sci."},{"key":"B10","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1097\/01.mlr.0000114908.90348.f9","article-title":"Variations in patients\u2019 adherence to medical recommendations: A quantitative review of 50 years of research","volume":"42","author":"Di Matteo","year":"2004","journal-title":"Med. Care"},{"key":"B11","doi-asserted-by":"publisher","first-page":"886","DOI":"10.4081\/monaldi.2018.886","article-title":"Inhalation therapy in the next decade: Determinants of adherence to treatment in asthma and COPD","volume":"88","author":"Donner","year":"2018","journal-title":"Monaldi Arch. Chest Dis."},{"key":"B12","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1097\/HCR.0000000000000318","article-title":"Effect of Inspiratory Muscle Training in the Management of Patients With Asthma: A RANDOMIZED CONTROLLED TRIAL","volume":"38","author":"Duruturk","year":"2018","journal-title":"J. Cardiopulm Rehabil. Prev."},{"key":"B13","doi-asserted-by":"publisher","first-page":"1157","DOI":"10.1007\/s40279-013-0077-2","article-title":"Effects of exercise training on","volume":"43","author":"Eichenberger","year":"2013","journal-title":"Sports Med."},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0050775","article-title":"Physical activity and asthma: a systematic review and meta-analysis","volume":"7","author":"Eijkemans","year":"2012","journal-title":"PloS One"},{"key":"B15","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1183\/09031936.00.15596900","article-title":"Breathing techniques\u2014adjunctive treatment modalities for asthma? A systematic review","volume":"15","author":"Ernst","year":"2000","journal-title":"Eur. Respir. J."},{"key":"B16","doi-asserted-by":"publisher","first-page":"1068","DOI":"10.4338\/ACI-2017-07-R-0116","article-title":"Patient Self-Management of Asthma Using Mobile Health Applications: A Systematic Review of the Functionalities and Effects","volume":"8","author":"Farzandipour","year":"2017","journal-title":"Appl. Clin. Inform."},{"key":"B17","doi-asserted-by":"publisher","first-page":"732","DOI":"10.1136\/thoraxjnl-2014-206070","article-title":"Aerobic training decreases bronchial hyperresponsiveness and systemic inflammation in patients with moderate or severe asthma: a randomised controlled trial","volume":"70","author":"Franca-Pinto","year":"2015","journal-title":"Thorax"},{"key":"B18","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1164\/rccm.201603-0446OC","article-title":"The role of exercise in a weight-loss program on clinical control in obese adults with asthma. A randomized controlled trial","volume":"195","author":"Freitas","year":"2017","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"B19","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1164\/rccm.200812-1929OC","article-title":"Prospective study of physical activity and risk of asthma exacerbations in older women","volume":"179","author":"Garcia-Aymerich","year":"2009","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"B20","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1177\/1757913918786528","article-title":"The use of motivational interviewing in improving medication adherence for individuals with asthma: a systematic review","volume":"138","author":"Gesinde","year":"2018","journal-title":"Perspect. Public Health"},{"key":"B21","unstructured":"Global Strategy for Asthma Management and Prevention2018"},{"key":"B22","doi-asserted-by":"publisher","first-page":"1136","DOI":"10.1164\/ajrccm.151.4.7697243","article-title":"Diaphragmatic breathing reduces efficiency of breathing in patients with chronic obstructive pulmonary disease","volume":"151","author":"Gosselink","year":"1995","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"B23","unstructured":"2020"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD011818.pub2","article-title":"Cognitive behavioral therapy (CBT) for","volume":"21","author":"Kew","year":"2016","journal-title":"Cochrane Database Syst. Rev."},{"key":"B25","doi-asserted-by":"publisher","first-page":"16017","DOI":"10.1038\/npjpcrm.2016.17","article-title":"Inhaler technique: facts and fantasies. A view from the Aerosol Drug management improvement Team (ADMIT)","volume":"26","author":"Levy","year":"2016","journal-title":"Prim Care Respir. Med."},{"key":"B26","doi-asserted-by":"publisher","first-page":"614","DOI":"10.3109\/02770903.2014.996650","article-title":"Asthma control and health-related","volume":"52","author":"Lingner","year":"2015","journal-title":"J. Asthma"},{"key":"B27","doi-asserted-by":"publisher","first-page":"928","DOI":"10.1016\/j.jaci.2005.01.033","article-title":"Physical activity and exercise in asthma: relevance to etiology and treatment","volume":"115","author":"Lucas","year":"2005","journal-title":"J. Allergy Clin. Immunol."},{"key":"B28","doi-asserted-by":"publisher","first-page":"856","DOI":"10.1111\/j.1440-1843.2008.01355.x","article-title":"Relationship between field walking tests and","volume":"13","author":"Luxton","year":"2008","journal-title":"Respirology"},{"key":"B29","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1164\/ajrccm.155.2.9032194","article-title":"Intensity of training and physiologic adaptation in patients with chronic obstructive pulmonary disease","volume":"155","author":"Maltais","year":"1997","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"B30","article-title":"Expert panel report III: Guidelines for the diagnosis and management of asthma","year":"2007"},{"key":"B31","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1016\/j.ccm.2014.02.015","article-title":"Pulmonary rehabilitation future directions","volume":"35","author":"Nici","year":"2014","journal-title":"Clin. Chest Med."},{"key":"B32","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1016\/j.jpsychores.2005.04.008","article-title":"Effect of progressive muscle relaxation in adolescent female bronchial asthma patients: a randomized, double-blind, controlled study","volume":"59","author":"Nickel","year":"2005","journal-title":"J. Psychosom Res."},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD012226.pub2","article-title":"Interventions to improve adherence to inhaled steroids for asthma","volume":"18","author":"Normansell","year":"2017","journal-title":"Cochrane Database Syst. Rev."},{"key":"B34","doi-asserted-by":"publisher","first-page":"1376","DOI":"10.1080\/02770903.2017.1414236","article-title":"Flexibility and strength training in asthma: A pilot study","volume":"55","author":"Olenich","year":"2018","journal-title":"J. Asthma."},{"key":"B35","doi-asserted-by":"publisher","first-page":"9(3","DOI":"10.3390\/jcm9030706","article-title":"Physical Activity: A Missing Link in Asthma Care","volume":"5","author":"Panagiotou","year":"2020","journal-title":"J. Clin. Med."},{"key":"B36","doi-asserted-by":"publisher","first-page":"2025","DOI":"10.1378\/chest.128.4.2025","article-title":"Exercise training decreases ventilatory requirements and exercise-induced hyperinflation at submaximal intensities in patients with COPD","volume":"128","author":"Porszasz","year":"2005","journal-title":"Chest"},{"key":"B37","doi-asserted-by":"publisher","first-page":"816","DOI":"10.7326\/0003-4819-145-11-200612050-00006","article-title":"Interval versus continuous high-intensity exercise in chronic obstructive pulmonary disease: a randomized trial","volume":"145","author":"Puhan","year":"2006","journal-title":"Ann. Intern Med."},{"key":"B38","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1097\/ACI.0000000000000494","article-title":"Asthma, obesity and targeted interventions: an update","volume":"19","author":"Ricketts","year":"2019","journal-title":"Curr. Opin. Allergy Clin. Immunol."},{"key":"B39","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1080\/02770903.2018.1443468","article-title":"Comparing the effect of pulmonary rehabilitation in patients with uncontrolled and partially controlled asthma","volume":"56","author":"Sahin","year":"2019","journal-title":"J. Asthma"},{"key":"B40","first-page":"277","article-title":"Exercise training in asthma","volume":"40","author":"Satta","year":"2000","journal-title":"J. Sports Med. Phys. Fitness"},{"key":"B41","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.rmed.2018.08.003","article-title":"Impact of a single 10 min education","volume":"143","author":"Schuermans","year":"2018","journal-title":"Respir. Med."},{"key":"B42","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1080\/00913847.2016.1176546","article-title":"The role of inspiratory muscle training in the management of asthma and exercise-induced bronchoconstriction","volume":"44","author":"Shei","year":"2016","journal-title":"Phys. Sportsmed."},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003792.pub2","article-title":"Inspiratory muscle training for asthma","volume":"8","author":"Silva","year":"2013","journal-title":"Cochrane Database Syst. Rev."},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002307","article-title":"Mast-cell stabilising agents to prevent exercise-induced bronchoconstriction","volume":"2003","author":"Spooner","year":"","journal-title":"Cochrane Database Syst. Rev."},{"key":"B45","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1164\/rccm.201309-1634ST","article-title":"On behalf of the ATS\/ERS Task Force on Pulmonary Rehabilitation. An Official American Thoracic Society\/European Respiratory Society Statement: key concepts and advances in pulmonary rehabilitation","volume":"188","author":"Spruit","year":"2013","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"B46","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.iac.2004.09.007","article-title":"Asthma associated with exercise","volume":"25","author":"Storms","year":"2005","journal-title":"Immunol. Allergy Clin. North Am."},{"key":"B47","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1097\/ACI.0b013e32834eca41","article-title":"Obesity and asthma disease phenotypes","volume":"12","author":"Stream","year":"2012","journal-title":"Curr. Opin. Allergy Clin. Immunol."},{"key":"B48","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1111\/nyas.12357","article-title":"Linking obesity and asthma","volume":"1311","author":"Sutherland","year":"2014","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1080\/20018525.2018.1468714","article-title":"Feasibility of high-intensity training in asthma","volume":"5","author":"Toennesen","year":"2018","journal-title":"Eur. Clin. Respir. J."},{"key":"B50","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1016\/j.jaip.2017.09.028","article-title":"Effects of Exercise and Diet in Nonobese Asthma Patients-A Randomized Controlled Trial","volume":"6","author":"Toennesen","year":"2018","journal-title":"J. Allergy Clin. Immunol. Pract."},{"key":"B51","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1097\/HCR.0000000000000249","article-title":"Effect of an outpatient pulmonary rehabilitation program on exercise tolerance and asthma control in obese asthma patients","volume":"37","author":"Turk","year":"2017","journal-title":"J. Cardiopulm Rehabil. Prev."},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/184678","article-title":"Cardiovascular function in pulmonary emphysema","volume":"2013","author":"Visca","year":"2013","journal-title":"BioMed. Res. Int."},{"key":"B53","doi-asserted-by":"publisher","first-page":"1802184","DOI":"10.1183\/13993003.02184-2018","article-title":"Pulmonary rehabilitation is effective in patients with tuberculosis pulmonary sequelae","volume":"53","author":"Visca","year":"2019","journal-title":"Eur. Respir. J."},{"key":"B54","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1016\/j.apmr.2011.11.026","article-title":"Diaphragmatic breathing training program improves abdominal motion during natural breathing in patients with chronic obstructive pulmonary disease: a randomized controlled trial","volume":"93","author":"Yamaguti","year":"2012","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD010346.pub2","article-title":"Yoga for asthma","author":"Yang","year":"2016","journal-title":"Cochrane Database Syst. Rev."},{"key":"B56","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1080\/02770903.2016.1229335","article-title":"A randomised controlled feasibility trial of Group Cognitive Behavioural Therapy for people with severe asthma","volume":"54","author":"Yorke","year":"2017","journal-title":"J. Asthma."},{"key":"B57","doi-asserted-by":"publisher","first-page":"1523","DOI":"10.4187\/respcare.06761","article-title":"Effectiveness of a pulmonary rehabilitation program on persistent asthma stratified for severity","volume":"64","author":"Zampogna","year":"2019","journal-title":"Respir. Care"},{"key":"B58","first-page":"1","article-title":"Effectiveness of pulmonary rehabilitation in severe asthma: a retrospective data analysis","volume-title":"J. Asthma","author":"Zampogna","year":"2019"}],"container-title":["Frontiers in Pharmacology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fphar.2020.00542\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,6]],"date-time":"2020-05-06T13:35:43Z","timestamp":1588772143000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fphar.2020.00542\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,6]]},"references-count":58,"alternative-id":["10.3389\/fphar.2020.00542"],"URL":"https:\/\/doi.org\/10.3389\/fphar.2020.00542","relation":{},"ISSN":["1663-9812"],"issn-type":[{"value":"1663-9812","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5,6]]},"article-number":"542"}}