{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T19:05:16Z","timestamp":1785351916745,"version":"3.55.0"},"reference-count":26,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,11,18]],"date-time":"2020-11-18T00:00:00Z","timestamp":1605657600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["S2011040005849"],"award-info":[{"award-number":["S2011040005849"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007162","name":"Guangdong Science and Technology Department","doi-asserted-by":"publisher","award":["2020B1111100006, 2020A1515010607, 2019A1515010636"],"award-info":[{"award-number":["2020B1111100006, 2020A1515010607, 2019A1515010636"]}],"id":[{"id":"10.13039\/501100007162","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pharmacol."],"DOI":"10.3389\/fphar.2020.558731","type":"journal-article","created":{"date-parts":[[2020,11,18]],"date-time":"2020-11-18T05:04:27Z","timestamp":1605675867000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":14,"title":["Metabonomics Study on Serum Characteristic Metabolites of Psoriasis Vulgaris Patients With Blood-Stasis Syndrome"],"prefix":"10.3389","volume":"11","author":[{"given":"Li","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan-ni","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing-wen","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian-an","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-hong","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuan-jian","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2020,11,18]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1016\/j.jep.2012.01.055","article-title":"Omic techniques in systems biology approaches to traditional Chinese medicine research: Present and future","volume":"140","author":"Alessandro","year":"2012","journal-title":"J. Ethnopharmacol."},{"key":"B2","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1007\/s11306-017-1185-z","article-title":"LysoPC-acyl C16:0 is associated with brown adipose tissue activity in men","volume":"13","author":"Boon","year":"2017","journal-title":"Metabolomics"},{"key":"B3","doi-asserted-by":"publisher","first-page":"76","DOI":"10.13288\/j.11-2166\/r.2014.01.021","article-title":"Evidence based clinical practice guide of traditional Chinese medicine for psoriasis vulgariVersion)","volume":"55","year":"2013","journal-title":"J. Tradit. Chin. Med."},{"key":"B4","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1111\/j.1365-2230.1994.tb01246.x","article-title":"The effect of topical application of the platelet-activating factor-antagonist, Ro 24-0238, in psoriasis vulgaris\u2013a clinical and immunohistochemical study","volume":"19","author":"Elbers","year":"2010","journal-title":"Clin. Exp. Dermatol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1159\/000505536","article-title":"Platelet Dysfunction and Its Role in the Pathogenesis of Psoriasis","author":"Fan","year":"2020","journal-title":"Dermatology"},{"key":"B6","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1111\/j.1365-2133.1997.tb14968.x","article-title":"Platelet activating factor in psoriasis","volume":"136","author":"Greaves","year":"1997","journal-title":"Br. J. Dermatol."},{"key":"B7","doi-asserted-by":"publisher","first-page":"1535","DOI":"10.1039\/c2mb25022e","article-title":"Plasma metabonomics study of rheumatoid arthritis and its Chinese medicine subtypes by using liquid chromatography and gas chromatography coupled with mass spectrometry","volume":"8","author":"Gu","year":"2012","journal-title":"Mol. Biosyst."},{"key":"B8","first-page":"DB44\/T 2120","article-title":"Psoriasis vulgar syndrome differentiation standard of traditional Chinese medicine","year":"2018"},{"key":"B9","doi-asserted-by":"publisher","first-page":"22","DOI":"10.13735\/j.cjdv.1001-7089.2014.0022","article-title":"The Distribution of TCM Syndromes of Vulgaris Psoriasis:Correspondence Analysis of the Relationships Between TCM Syndromes and Disease Stages","volume":"28","author":"He","year":"2014","journal-title":"Chin. J. Dermatovenereol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1007\/BF00371796","article-title":"Platelet activating factor (PAF) and lyso-PAF in psoriasis[J]","volume":"286","author":"Judge","year":"1994","journal-title":"Arch. Dermatol. Res."},{"key":"B11","first-page":"959","article-title":"Distribution of Chinese Medical Syndrome in Ordinary Psoriasis: Literature from 1979 to 2010","volume":"53","author":"Lu","year":"2010","journal-title":"J. Tradit. Chin. Med."},{"key":"B12","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1007\/s11655-012-1006-1","article-title":"Disease-syndrome combination clinical study of psoriasis: Present status, advantages, and prospects","volume":"18","author":"Lu","year":"2012","journal-title":"Chin. J. Integr. Med."},{"key":"B13","doi-asserted-by":"publisher","first-page":"1060","DOI":"10.1111\/j.1365-2230.1994.tb01246.x","article-title":"Platelet-activating factor and arachidonic acid metabolites in psoriatic inflammation","volume":"134","author":"Lzaki","year":"1996","journal-title":"Br. J. Dermatol."},{"key":"B14","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1056\/NEJMra0804595","article-title":"Psoriasis","volume":"361","author":"Nestle","year":"2009","journal-title":"N. Engl. J. Med."},{"key":"B15","doi-asserted-by":"publisher","first-page":"1181","DOI":"10.1080\/004982599238047","article-title":"\u2018Metabonomics\u2019: understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data","volume":"29","author":"Nicholson","year":"1999","journal-title":"Xenobiotica"},{"key":"B16","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1111\/j.1529-8019.2010.01311.x","article-title":"Psoriasis and serum lipid abnormalities","volume":"23","author":"Pietrzak","year":"2010","journal-title":"Dermatol. Ther."},{"key":"B17","doi-asserted-by":"publisher","first-page":"369","DOI":"10.5114\/aoms.2018.74021","article-title":"Serum lipid metabolism in psoriasis and psoriatic arthritis - An update","volume":"15","author":"Pietrzak","year":"2019","journal-title":"Arch. Med. Sci."},{"key":"B18","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1590\/abd1806-4841.20142874","article-title":"Comorbidities and cardiovascular risk factors in patients with psoriasis","volume":"89","author":"Ribeiro","year":"2014","journal-title":"Anais Brasileiros Dermatol."},{"key":"B19","first-page":"343","article-title":"Serum lipids and lipoproteins in patients with psoriasis","volume":"17","author":"Taheri","year":"2014","journal-title":"Arch. Iranian Med."},{"key":"B20","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1097\/MOP.0b013e328341d1da","article-title":"Correlation between blood-stasis tongue figure and platelet activating factor (PAF) and acetyl hydrolase of PAF (PAF-AH) in patients with primary dysmenorrhea","volume":"31","author":"Yang","year":"2011","journal-title":"Zhongguo Zhong XI Yi Jie He Za Zhi"},{"key":"B21","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1093\/gigascience\/gix087","article-title":"Lipidomics profiling reveals the role of glycerophospholipid metabolism in psoriasis","volume":"6","author":"Zeng","year":"2017","journal-title":"Gigascience"},{"key":"B22","first-page":"894","article-title":"Study on the distribution and development rules of TCM syndromes of 2651 psoriasis vulgaris cases","volume":"29","author":"Zhang","year":"2008","journal-title":"J. Tradit. Chin. Med."},{"key":"B23","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/S0254-6272(09)60064-9","article-title":"Distribution and Development of the TCM Syndromes in Psoriasis Vulgaris","volume":"29","author":"Zhang","year":"2009","journal-title":"J. Tradit. Chin. Med."},{"key":"B24","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1007\/BF02934397","article-title":"Preliminary study on essence of TCM syndrome typing of psoriasis and its objective basis","volume":"8","author":"Zhang","year":"2002","journal-title":"CJIM"},{"key":"B25","doi-asserted-by":"publisher","first-page":"1419","DOI":"10.1007\/s10753-012-9455-4","article-title":"Elevated Plasma Platelet Activating Factor, Platelet Activating Factor Acetylhydrolase Levels and Risk of Coronary Heart Disease or Blood Stasis Syndrome of Coronary Heart Disease in Chinese: A Case Control Study[J]","volume":"35","author":"Zheng","year":"2012","journal-title":"Inflammation"},{"key":"B26","doi-asserted-by":"publisher","first-page":"1994","DOI":"10.1021\/acs.jproteome.8b00799","article-title":"A Large-Scale, Multi-Center Urine Biomarkers Identification of Coronary Heart Disease in TCM Syndrome Differentiation","volume":"18","author":"Zhou","year":"2019","journal-title":"J. Proteome Res."}],"container-title":["Frontiers in Pharmacology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fphar.2020.558731\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,18]],"date-time":"2020-11-18T05:04:34Z","timestamp":1605675874000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fphar.2020.558731\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,18]]},"references-count":26,"alternative-id":["10.3389\/fphar.2020.558731"],"URL":"https:\/\/doi.org\/10.3389\/fphar.2020.558731","relation":{},"ISSN":["1663-9812"],"issn-type":[{"value":"1663-9812","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,18]]},"article-number":"558731"}}