{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:14:12Z","timestamp":1753892052758,"version":"3.41.2"},"reference-count":59,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T00:00:00Z","timestamp":1745798400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010272","name":"Zarqa University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010272","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pharmacol."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Magnesium is a vital mineral with a crucial role in different biochemical reactions. There is a contradicting evidences about its role in maintaining bone, muscle and cardiovascular health. Recently, magnesium supplements gained attention due to claimed effectiveness in improving sleep quality and relieving muscle spasm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>This study aimed to assess Arab communities\u2019 knowledge, attitudes and practices regarding magnesium supplementation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross-sectional self-administered survey was disseminated to collect responses from different Arab countries. Descriptive statistics were calculated for demographics. Data normality was assessed using Shapiro-Wilk test. Associations between sociodemographic variables and knowledge, attitudes and practices were explored using simple and multiple linear regression. Significance level was considered at p &amp;lt; 0.05.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 1,445 responses were collected. Mean (\u00b1SD) knowledge scores were low 8.61 \u00b1 5.9. Eighty seven percent recognized magnesium role in alleviating muscle spasm and sleep disorders (83%). Magnesium citrate was the mostly used magnesium salt (37.43%). Neutral attitudes were observed with a mean score of 3.02 \u00b1 0.66. Only 31.8% reported using magnesium supplements, 36.1% of them received a medical consultation. Having poly cystic ovary (p = 0.033), relying on scientific articles (0.004), receiving pharmacist consultation (p = 0.019) significantly associated with higher knowledge.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Despite the huge debate regarding magnesium benefits in maintaining muscle, bone health and improving sleep quality, this study found that there is a significant gap in knowledge and neutral attitude towards magnesium supplementation in Arab communities. These findings emphasizes the need for educational campaigns targeting the public on the rationale use of supplements.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fphar.2025.1550695","type":"journal-article","created":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T08:23:39Z","timestamp":1745828619000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["A multinational cross-sectional study on knowledge, attitudes, and practices towards magnesium supplements"],"prefix":"10.3389","volume":"16","author":[{"given":"Rana","family":"Abutaima","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muna","family":"Barakat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samar","family":"Thiab","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hana M.","family":"Sawan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malak","family":"Amer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reem","family":"Alzayer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doaa H.","family":"Abdelaziz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noha O.","family":"Mansour","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatima","family":"Saleh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wael Abu","family":"Dayyih","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,4,28]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1327576","DOI":"10.3389\/fphar.2023.1327576","article-title":"Impact of a pharmacist-led educational intervention on knowledge, attitude, and practice toward the rational use of antibiotics among healthcare workers in a secondary care hospital in Punjab, Pakistan","volume":"14","author":"Afzal","year":"2023","journal-title":"Front. 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