{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T12:11:39Z","timestamp":1785240699036,"version":"3.55.0"},"reference-count":15,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,9,18]],"date-time":"2025-09-18T00:00:00Z","timestamp":1758153600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pharmacol."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The engagement of clinical pharmacists in ward-based care remains limited in our hospital. This study explores a novel pharmacist working model (resident pharmacists) and evaluates its effectiveness to provide evidence for optimizing pharmaceutical services in intensive care units (ICUs).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From February 2024 to January 2025, resident pharmacists were embedded within the Liver ICU as part of a pilot program, delivering multidisciplinary pharmaceutical services including clinical care, teaching, research, and management. Specialized interventions targeting pediatric and infectious disease populations were implemented based on departmental needs. A retrospective analysis was conducted over 12\u00a0months to assess the impact of resident pharmacists on pharmaceutical indicators, service quality, and staff satisfaction; key outcome measures included cost reduction, prescribing appropriateness, and antibiotic use metrics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All pharmaceutical management metrics met institutional standards in 2024-2025, including Antibiotic Use Density (AUD; 112.30 vs. threshold 120.47), antimicrobial usage rate (78.68% vs. 88.54%), and proton pump inhibitor prescription rationality (100%). Pharmacists conducted 78 clinical consultations (65.38% multidisciplinary), addressed 132 medication inquiries, developed two clinical guidelines, and achieved full satisfaction scores from medical staff. The average drug cost per patient decreased by 20.05% (RMB 28,806 vs. 36,028 in 2023), with drug cost proportion declining from 30.85% to 23.59%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>By deeply participating in various aspects of drug use in the wards, including medical work, management, scientific research cooperation, continuing medical education, resident pharmacists provided more high-quality pharmaceutical services and promote the improvement of pharmaceutical quality control indicators. Resident pharmacists have become important members of the medical team responsible for medication safety and optimizing treatment plans.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fphar.2025.1583818","type":"journal-article","created":{"date-parts":[[2025,9,18]],"date-time":"2025-09-18T05:32:33Z","timestamp":1758173553000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Retrospective evaluation of resident pharmacists\u2019 services in a liver intensive care unit: a single-center experience"],"prefix":"10.3389","volume":"16","author":[{"given":"Huijie","family":"Meng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaoshuai","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenyu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanyuan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangmeng","family":"Nie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,9,18]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"100431","DOI":"10.1016\/j.rcsop.2024.100431","article-title":"Clinical pharmacist interventions in an intensive care unit reduces ICU mortality at a tertiary hospital in Dubai, United Arab Emirates","volume":"14","author":"Ali Hussain Alsayed","year":"2024","journal-title":"Explor. 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