{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T05:02:21Z","timestamp":1785301341532,"version":"3.55.0"},"reference-count":78,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T00:00:00Z","timestamp":1785283200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003141","name":"Secretar\u00eda de Ciencia, Humanidades, Tecnolog\u00eda e Innovaci\u00f3n","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pharmacol."],"abstract":"<jats:p>\n                    Acrylamide, bisphenols, phthalates, and micro- and nanoplastics are pervasive environmental pollutants with well-documented carcinogenic, neurotoxic, and reproductive effects. Nonetheless, their potential contribution to cardiovascular diseases remains strikingly unrecognised, despite the rising incidence of their clinical manifestations in younger populations and growing evidence of their effects on haemostasis and thrombosis. Single- and dual-antiplatelet therapy only partially controls the prothrombotic phenotype driven by thromboinflammation, whilst the role of plastics as platelet aggregation enhancers remains an under-addressed gap in current cardiovascular disease prevention strategies. This mini-review synthesises 11\u00a0years of\n                    <jats:italic>ex vivo<\/jats:italic>\n                    human and\n                    <jats:italic>in vivo<\/jats:italic>\n                    rodent evidence on the haemostatic effects of plastics, with attention to platelet aggregation, blood coagulation parameters, and their possible mechanisms. Bisphenols dominate the available literature, skewing the evidence towards their haemostatic effects relative to findings on acrylamide and phthalates. Regarding micro- and nanoplastics, most evidence has come from microplastics, owing to analytical challenges in quantifying nanoplastics. Because exposure to plastics and their complex chemical mixtures remains largely unregulated, the collated evidence on their cardiovascular effects should prompt regulatory action. Our review also highlights the research gaps to be prioritised in future toxicological approaches, as well as the need to integrate coagulation markers to establish dose-response thresholds of public health relevance.\n                  <\/jats:p>","DOI":"10.3389\/fphar.2026.1870771","type":"journal-article","created":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T04:33:29Z","timestamp":1785299609000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Unmasking the haemostatic potential of quotidian plastics: upon first glance"],"prefix":"10.3389","volume":"17","author":[{"given":"Roc\u00edo","family":"Gomez","sequence":"first","affiliation":[{"name":"Departamento de Toxicolog\u00eda, Centro de Investigaci\u00f3n y de Estudios Avanzados del Instituto Polit\u00e9cnico Nacional","place":["Mexico City, Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yesenia I.","family":"Martinez-Jimenez","sequence":"additional","affiliation":[{"name":"Departamento de Toxicolog\u00eda, Centro de Investigaci\u00f3n y de Estudios Avanzados del Instituto Polit\u00e9cnico Nacional","place":["Mexico City, Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco Antonio","family":"Meraz R\u00edos","sequence":"additional","affiliation":[{"name":"Departamento de Biomedicina Molecular, Centro de Investigaci\u00f3n y de Estudios Avanzados del Instituto Polit\u00e9cnico Nacional","place":["Mexico City, Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,7,29]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"108956","DOI":"10.1016\/j.jfca.2026.108956","article-title":"Micro-nanoplastics in livestock and poultry: emerging components of food matrices","volume":"151","author":"Abad-Lopez","year":"2026","journal-title":"J. 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