{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T06:04:57Z","timestamp":1789538697306,"version":"build-2803163510"},"reference-count":160,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:00:00Z","timestamp":1789516800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pharmacol."],"abstract":"<jats:p>\n                    <jats:italic>Artemisia<\/jats:italic>\n                    species are integral to traditional Korean medicine and are increasingly used in medicinal and cosmeceutical products. However, taxonomic ambiguity, chemical variability, and limited clinical validation constrain their reliable therapeutic and commercial utilization. This review critically examines how phylogenomic evidence can be integrated with ethnopharmacology and phytochemistry to strengthen the authentication, scientific evaluation, and quality-controlled development of\n                    <jats:italic>Artemisia<\/jats:italic>\n                    taxa occurring in Korea. Its distinctive contribution is a Korea-focused synthesis linking chloroplast-genome variation, traditional medicinal categories, species-associated phytochemical profiles, pharmacological evidence, and commercial quality requirements. Complete plastome analyses provide greater phylogenetic resolution than many single-locus approaches, whereas variable regions such as\n                    <jats:italic>ycf1<\/jats:italic>\n                    ,\n                    <jats:italic>accD<\/jats:italic>\n                    , and selected intergenic spacers offer candidate markers for species authentication. Nevertheless, chloroplast-based identification may remain insufficient for closely related taxa and should be complemented by nuclear markers, morphology, and chemical profiling. Korean\n                    <jats:italic>Artemisia<\/jats:italic>\n                    taxa contain sesquiterpene lactones, flavonoids, phenolic acids, and volatile terpenoids associated mainly with anti-inflammatory, antioxidant, antimicrobial, and hepatoprotective effects in preclinical studies. These findings should not be interpreted as established clinical efficacy. Plastome divergence alone does not directly explain specialized-metabolite production or therapeutic activity. Future research should prioritize authenticated germplasm, integrated multi-omics, standardized extraction, toxicological and clinical validation, sustainable cultivation, and harmonized regulatory quality control.\n                  <\/jats:p>","DOI":"10.3389\/fphar.2026.1873437","type":"journal-article","created":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T05:32:39Z","timestamp":1789536759000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Korean Artemisia species: phylogenomic authentication, ethnopharmacology, and commercial applications"],"prefix":"10.3389","volume":"17","author":[{"given":"Adnan","family":"Amin","sequence":"first","affiliation":[{"name":"Department of Life Sciences, Yeungnam University","place":["Gyeongsan, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khizar","family":"Abbas","sequence":"additional","affiliation":[{"name":"School of Pharmacy, University College London","place":["London, United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mozaniel Santana","family":"de Oliveira","sequence":"additional","affiliation":[{"name":"Laboratory of Pharmacology of Inflammation and Behavior, Graduate Program in Pharmaceutical Sciences, Institute of Health Sciences, Federal University of Par\u00e1","place":["Bel\u00e9m, Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,16]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"2542","DOI":"10.3390\/molecules17032542","article-title":"The Artemisia L. genus: a review of bioactive essential oils","volume":"17","author":"Abad","year":"2012","journal-title":"Molecules"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1268","DOI":"10.1016\/j.sjbs.2016.01.001","article-title":"Ecological variations and role of heat shock protein in Artemisia judaica L. in response to temperature regimes of Tabuk, Saudi Arabia","volume":"24","author":"Abbas","year":"2016","journal-title":"Saudi J. Biol. Sci."},{"key":"B4","first-page":"548","volume-title":"What is In-Jin-Sook? Artemisia capillaris, Artemisia Iwayomogi, and Artemisia annua Korean J. Hepatol","author":"Ahn","year":"2000"},{"key":"B5","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1080\/07388551.2016.1261082","article-title":"Strategies to enhance biologically active-secondary metabolites in cell cultures of Artemisia\u2013current trends","volume":"37","author":"Ali","year":"2017","journal-title":"Crit. Rev. Biotechnol."},{"key":"B6","doi-asserted-by":"publisher","first-page":"2364","DOI":"10.3390\/plants14152364","article-title":"Harnessing molecular phylogeny and chemometrics for taxonomic validation of Korean aromatic plants: integrating genomics with practical applications","volume":"14","author":"Amin","year":"2025","journal-title":"Plants"},{"key":"B8","doi-asserted-by":"publisher","first-page":"1179","DOI":"10.1113\/ep092157","article-title":"The state of mechanistic research in the evidence\u2010based medicine era: a sandwalk between triangulation and hierarchies","volume":"110","author":"Berg","year":"2025","journal-title":"Exp. Physiol."},{"key":"B9","doi-asserted-by":"publisher","first-page":"1002","DOI":"10.1080\/10408347.2022.2105641","article-title":"Bioactive flavonoids: a comprehensive review on pharmacokinetics and analytical aspects","volume":"54","author":"Billowria","year":"2022","journal-title":"Crit. Rev. Anal. Chem."},{"key":"B10","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1007\/s12272-021-01328-4","article-title":"Phytochemistry and pharmacological activity of the genus Artemisia","volume":"44","author":"Bisht","year":"2021","journal-title":"Arch. Pharmacal Res."},{"key":"B11","doi-asserted-by":"publisher","first-page":"101","DOI":"10.3109\/13880209.2010.497815","article-title":"The genus Artemisia: a comprehensive review","volume":"49","author":"Bora","year":"2011","journal-title":"Pharm. Biol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"1713657","DOI":"10.3389\/fpls.2025.1713657","article-title":"Transcriptome and metabolome analyses revealed the main profiles contributing the mild aroma characteristics of Artemisia stolonifera","volume":"16","author":"Cao","year":"2025","journal-title":"Front. Plant Sci."},{"key":"B13","first-page":"322","article-title":"Effects of Artemisia iwayomogi on the airway smooth muscle","volume":"16","author":"Chan","year":"2002","journal-title":"J. Physiology Pathology Korean Med."},{"key":"B14","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1111\/eva.12440","article-title":"Climate drives adaptive genetic responses associated with survival in big sagebrush (Artemisia tridentata)","volume":"10","author":"Chaney","year":"2017","journal-title":"Evol. Appl."},{"key":"B15","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1186\/s13020-016-0108-7","article-title":"Conservation and sustainable use of medicinal plants: problems, progress, and prospects","volume":"11","author":"Chen","year":"2016","journal-title":"Chin. Med."},{"key":"B16","doi-asserted-by":"publisher","first-page":"100516","DOI":"10.1016\/j.xplc.2023.100516","article-title":"A chromosome-scale genome assembly of Artemisia argyi reveals unbiased subgenome evolution and key contributions of gene duplication to volatile terpenoid diversity","volume":"4","author":"Chen","year":"2023","journal-title":"Plant Commun."},{"key":"B17","doi-asserted-by":"publisher","first-page":"e002","DOI":"10.48130\/mpb-0024-0002","article-title":"Comprehensive review of botanical characteristics, artificial cultivation methods, quality evaluation, genome research, and potential applications of Artemisia argyi L\u00e9vl. et Van","volume":"3","author":"Chen","year":"","journal-title":"Med. Plant Biol."},{"key":"B18","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1111\/plb.13608","article-title":"Complete chloroplast genomes of eight Artemisia species: Comparative analysis, molecular identification, and phylogenetic analysis","volume":"26","author":"Chen","year":"","journal-title":"Plant Biol."},{"key":"B19","doi-asserted-by":"publisher","first-page":"e70548","DOI":"10.1111\/tpj.70548","article-title":"Comparative genomic analysis of Artemisia argyi reveals asymmetric expansion of terpene synthases and conservation of artemisinin biosynthesis","volume":"124","author":"Chen","year":"2025","journal-title":"Plant J."},{"key":"B20","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1016\/s0254-6272(13)60107-7","article-title":"Anticancer, antiobesity, and anti-inflammatory activity of Artemisia species in vitro","volume":"33","author":"Choi","year":"2013","journal-title":"J. Traditional Chin. Med."},{"key":"B21","doi-asserted-by":"publisher","first-page":"79","DOI":"10.11110\/kjpt.2023.53.2.79","article-title":"A checklist of endemic plants on the Korean Peninsula II","volume":"53","author":"Chung","year":"2023","journal-title":"Korean J. Plant Taxonomy"},{"key":"B22","doi-asserted-by":"publisher","first-page":"1299","DOI":"10.1111\/1541-4337.12518","article-title":"Bioavailability and metabolism of chlorogenic acids (acyl-quinic acids) in humans","volume":"19","author":"Clifford","year":"2020","journal-title":"Compr. Rev. Food Sci. Food Safety"},{"key":"B23","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1007\/s00425-022-03889-0","article-title":"Morphogenesis, ultrastructure, and chemical profiling of trichomes in Artemisia argyi H. L\u00e9v. and Vaniot (Asteraceae)","volume":"255","author":"Cui","year":"2022","journal-title":"Planta"},{"key":"B24","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1186\/s13059-016-1004-2","article-title":"Chloroplast genomes: diversity, evolution, and applications in genetic engineering","volume":"17","author":"Daniell","year":"2016","journal-title":"Genome Biol."},{"key":"B25","doi-asserted-by":"publisher","first-page":"2257","DOI":"10.1111\/1750-3841.14273","article-title":"Identification and quantification of thujone in a case of poisoning due to repeated ingestion of an infusion of Artemisia vulgaris L","volume":"83","author":"Di Lorenzo","year":"2018","journal-title":"J. Food Science"},{"key":"B26","doi-asserted-by":"publisher","first-page":"1466578","DOI":"10.3389\/fphar.2024.1466578","article-title":"A comparative analysis of chloroplast genomes revealed the chloroplast heteroplasmy of Artemisia annua","volume":"15","author":"Ding","year":"2024","journal-title":"Front. Pharmacol."},{"key":"B27","doi-asserted-by":"publisher","first-page":"7043436","DOI":"10.1155\/2016\/7043436","article-title":"Application of partial internal transcribed spacer sequences for the discrimination of Artemisia capillaris from other Artemisia species","volume":"2016","author":"Doh","year":"2016","journal-title":"Evid. Based Complement. Altern. Med."},{"key":"B28","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1055\/a-1345-9528","article-title":"Artemisia annua\u2013importance in traditional medicine and current state of knowledge on the chemistry, biological activity and possible applications","volume":"87","author":"Ekiert","year":"2021","journal-title":"Planta Medica"},{"key":"B29","doi-asserted-by":"publisher","first-page":"6427","DOI":"10.3390\/molecules27196427","article-title":"Artemisia species with high biological values as a potential source of medicinal and cosmetic raw materials","volume":"27","author":"Ekiert","year":"2022","journal-title":"Molecules"},{"key":"B30","doi-asserted-by":"publisher","first-page":"688","DOI":"10.3109\/08923971003677808","article-title":"Sesquiterpene lactone fraction from Artemisia khorassanica inhibits inducible nitric oxide synthase and cyclooxygenase-2 expression through the inactivation of NF-\u03baB","volume":"32","author":"Emami","year":"2010","journal-title":"Immunopharmacol. Immunotoxicol."},{"key":"B31","doi-asserted-by":"publisher","first-page":"222","DOI":"10.3389\/fpls.2012.00222","article-title":"Flavonoids: biosynthesis, biological functions, and biotechnological applications","volume":"3","author":"Falcone Ferreyra","year":"2012","journal-title":"Front. Plant Science"},{"key":"B32","doi-asserted-by":"publisher","first-page":"588","DOI":"10.3390\/ijms17050588","article-title":"Herbal hepatotoxicity: clinical characteristics and listing compilation","volume":"17","author":"Frenzel","year":"2016","journal-title":"Int. J. Mol. Sci."},{"key":"B33","doi-asserted-by":"publisher","first-page":"48","DOI":"10.3390\/pharmaceutics13010048","article-title":"The biosimilar landscape: an overview of regulatory approvals by the EMA and FDA","volume":"13","author":"Gherghescu","year":"2020","journal-title":"Pharmaceutics"},{"key":"B34","doi-asserted-by":"publisher","first-page":"13516","DOI":"10.3390\/ijms241713516","article-title":"Chlorogenic acid alleviates LPS-Induced inflammation and oxidative stress by modulating CD36\/AMPK\/PGC-1\u03b1 in RAW264.7 macrophages","volume":"24","author":"Gu","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"B35","doi-asserted-by":"publisher","first-page":"700","DOI":"10.3390\/metabo14120700","article-title":"Enhanced synthesis of volatile compounds by UV-B irradiation in Artemisia argyi leaves","volume":"14","author":"Gu","year":"2024","journal-title":"Metabolites"},{"key":"B36","doi-asserted-by":"publisher","first-page":"659","DOI":"10.3390\/genes16060659","article-title":"Comparative analysis of plastomes of Artemisia and insights into the infra-generic phylogenetic relationships within the genus","volume":"16","author":"Guo","year":"2025","journal-title":"Genes"},{"key":"B37","doi-asserted-by":"publisher","first-page":"3206","DOI":"10.3892\/mmr.2016.5657","article-title":"Ameliorative effects of Artemisia argyi folium extract on 2,4-dinitrochlorobenzene-induced atopic dermatitis-like lesions in BALB\/c mice","volume":"14","author":"Han","year":"2016","journal-title":"Mol. Med. Rep."},{"key":"B38","doi-asserted-by":"publisher","first-page":"1412416","DOI":"10.3389\/fpls.2024.1412416","article-title":"Transcriptome dynamics in Artemisia annua provides new insights into cold adaptation and de-adaptation","volume":"15","author":"He","year":"2024","journal-title":"Front. Plant Sci."},{"key":"B39","doi-asserted-by":"publisher","first-page":"953205","DOI":"10.3389\/fphar.2022.953205","article-title":"Best practice in the chemical characterisation of extracts used in pharmacological and toxicological research\u2014the ConPhyMP\u2014guidelines","volume":"13","author":"Heinrich","year":"2022","journal-title":"Front. Pharmacol."},{"key":"B40","doi-asserted-by":"publisher","first-page":"3826","DOI":"10.1073\/pnas.070042397","article-title":"Alpha-thujone (the active component of absinthe): gamma-aminobutyric acid type A receptor modulation and metabolic detoxification","volume":"97","author":"H\u00f6ld","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"B41","doi-asserted-by":"publisher","first-page":"12794","DOI":"10.1073\/pnas.0905845106","article-title":"A DNA barcode for land plants","volume":"106","author":"Hollingsworth","year":"2009","journal-title":"Proc. Natl. Acad. Sci."},{"key":"B42","doi-asserted-by":"publisher","first-page":"657","DOI":"10.3746\/jkfn.2007.36.6.657","article-title":"Antioxidative properties of Artemisia princeps pamp","volume":"36","author":"Hong","year":"2007","journal-title":"J. Korean Soc. Food Sci. Nutr."},{"key":"B43","doi-asserted-by":"publisher","first-page":"1131","DOI":"10.3390\/molecules28031131","article-title":"Multivariate analysis of essential oil composition of Artemisia annua L. collected from different locations in Korea","volume":"28","author":"Hong","year":"2023","journal-title":"Molecules"},{"key":"B44","doi-asserted-by":"publisher","first-page":"301","DOI":"10.2174\/1568026623666230914104141","article-title":"Traditional uses, phytochemistry, pharmacology, and toxicology of the genus Artemisia L.(Asteraceae): a high-value medicinal plant","volume":"24","author":"Hussain","year":"2024","journal-title":"Curr. Top. Med. Chem."},{"key":"B45","doi-asserted-by":"publisher","first-page":"377","DOI":"10.5352\/jls.2014.24.4.377","article-title":"Physicochemical characteristics and biological activities of Artemisia argyi H","volume":"24","author":"Hwang","year":"2014","journal-title":"J. Life Sci."},{"key":"B46","doi-asserted-by":"publisher","first-page":"4219","DOI":"10.1080\/10408398.2022.2140120","article-title":"Quality evaluation of commercial herbal products using chemical methods","volume":"64","author":"Ichim","year":"2022","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"B47","doi-asserted-by":"publisher","first-page":"247685","DOI":"10.1155\/2015\/247685","article-title":"Sesquiterpene lactones from Artemisia genus: biological activities and methods of analysis","volume":"2015","author":"Iv\u0103nescu","year":"2015","journal-title":"J. Anal. Methods Chem."},{"key":"B48","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1007\/s40415-019-00521-6","article-title":"Comparative anatomical investigation of five Artemisia L.(Anthemideae, Asteraceae) species in view of taxonomy","volume":"42","author":"Jana\u0107kovi\u0107","year":"2019","journal-title":"Braz. J. Bot."},{"key":"B49","volume-title":"Exploring Artemisia for Skin Diseases: A Natural Approach to Dermatological Therapy","author":"Jenis","year":"2025"},{"key":"B50","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1080\/09540105.2018.1439454","article-title":"In vitro anti-inflammatory activity of the Artemisia montana leaf ethanol extract in macrophage RAW 264.7 cells","volume":"29","author":"Jeong","year":"2018","journal-title":"Food Agric. Immunol."},{"key":"B51","doi-asserted-by":"publisher","first-page":"6466","DOI":"10.3390\/molecules15096466","article-title":"Effects of Eupatilin and Jaceosidin on cytochrome P450 enzyme activities in human liver microsomes","volume":"15","author":"Ji","year":"2010","journal-title":"Molecules"},{"key":"B52","doi-asserted-by":"publisher","first-page":"867","DOI":"10.1093\/aob\/mcad051","article-title":"Phylogenomics and morphological evolution of the mega-diverse genus Artemisia (Asteraceae: anthemideae): implications for its circumscription and infrageneric taxonomy","volume":"131","author":"Jiao","year":"2023","journal-title":"Ann. Bot."},{"key":"B53","doi-asserted-by":"publisher","first-page":"8648","DOI":"10.1038\/s41467-025-64039-0","article-title":"Global phylogeny and taxonomy of Artemisia","volume":"16","author":"Jiao","year":"2025","journal-title":"Nat. Commun."},{"key":"B54","doi-asserted-by":"publisher","first-page":"120428","DOI":"10.1016\/j.jep.2025.120428","article-title":"Safety and efficacy of Artemisia argyi extract RW0117 for functional dyspepsia: a randomized, double-blind, placebo-controlled clinical study","volume":"353","author":"Jin","year":"2025","journal-title":"J. Ethnopharmacol."},{"key":"B55","doi-asserted-by":"publisher","first-page":"153501","DOI":"10.1016\/j.phymed.2021.153501","article-title":"Artemisiae iwayomogii herba inhibits lipopolysaccharide-induced neuroinflammation by regulating NF-\u03baB and MAPK signaling pathways","volume":"84","author":"Ju","year":"2021","journal-title":"Phytomedicine"},{"key":"B56","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1007\/s10142-024-01464-2","article-title":"Complete chloroplast genome sequence of Artemisia littoricola (Asteraceae) from Dokdo Island Korea: genome structure, phylogenetic analysis, and biogeography study","volume":"24","author":"Kadam","year":"2024","journal-title":"Funct. Integr. Genomics"},{"key":"B57","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1080\/23802359.2016.1159926","article-title":"The complete chloroplast genome sequence of medicinal plant, Artemisia argyi","volume":"1","author":"Kang","year":"2016","journal-title":"Mitochondrial DNA B Resour."},{"key":"B58","doi-asserted-by":"publisher","first-page":"267","DOI":"10.11002\/fsp.2024.31.2.267","article-title":"Comparison of the physicochemical properties of native and cultivated Artemisia fukudo Makino","volume":"31","author":"Kang","year":"2024","journal-title":"Food Sci. Preserv."},{"key":"B161","doi-asserted-by":"publisher","first-page":"375","DOI":"10.7783\/KJMCS.2025.33.6.375","article-title":"Sesamin from Artemisia littoricola attenuates UVA-induced MMP expression in human dermal fibroblasts","volume":"33","author":"Karadeniz","year":"2025","journal-title":"Korean J. Med. Crop Sci."},{"key":"B59","doi-asserted-by":"publisher","first-page":"P-266","DOI":"10.1055\/s-0043-1774138","article-title":"Anti-inflammatory effects of Artemisia argyi and A. princeps extract in mice with contact dermatitis in vitro and in vivo","volume":"89","author":"Kim","year":"2023","journal-title":"Planta Med."},{"key":"B60","doi-asserted-by":"publisher","first-page":"345","DOI":"10.7783\/kjmcs.2021.29.5.345","article-title":"Antioxidant activities and phenolic compounds of extract from Hallasan wormwood","volume":"29","author":"Kim","year":"2021","journal-title":"\ud55c\uad6d\uc57d\uc6a9\uc791\ubb3c\ud559\ud68c\uc9c0"},{"key":"B61","first-page":"348","article-title":"Anti-obestic effects of Artemisiae capillaris herba, Artemisia capillaris stem aqueous extracts on the high fat diet supplied mice","volume":"27","author":"Kim","year":"2010","journal-title":"J. Veterinary Clinics"},{"key":"B62","doi-asserted-by":"publisher","first-page":"117","DOI":"10.4236\/jacen.2013.24017","article-title":"Cultivation characteristics and flavonoid contents of wormwood (Artemisia montana Pamp.)","volume":"2","author":"Kim","year":"2013","journal-title":"J. Agric. Chem. Environ."},{"key":"B63","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.1007\/s12272-014-0543-x","article-title":"Chemical constituents on the aerial parts of Artemisia selengensis and their IL-6 inhibitory activity","volume":"38","author":"Kim","year":"","journal-title":"Archives Pharmacal Res."},{"key":"B64","doi-asserted-by":"publisher","first-page":"21","DOI":"10.4196\/kjpp.2015.19.1.21","article-title":"Anti-inflammatory, antioxidant and antimicrobial effects of artemisinin extracts from Artemisia annua L","volume":"19","author":"Kim","year":"","journal-title":"Korean J. Physiology Pharmacol."},{"key":"B65","first-page":"233","article-title":"Antimelanogenic of Artemisia fukudo Makino Extract in Melanoma Cells","volume-title":"Korean Soc. Biotechnol. Bioeng. J.","author":"Kim","year":"2017"},{"key":"B66","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1186\/s40543-019-0193-1","article-title":"In vitro and in vivo anti-aging effects of compounds isolated from Artemisia iwayomogi","volume":"10","author":"Kim","year":"","journal-title":"J. Anal. Sci. Technol."},{"key":"B67","doi-asserted-by":"publisher","first-page":"1741","DOI":"10.3892\/ijmm.2019.4334","article-title":"Polyphenol mixture of a native Korean variety of Artemisia argyi H. (Seomae mugwort) and its anti-inflammatory effects","volume":"44","author":"Kim","year":"","journal-title":"Int. J. Mol. Med."},{"key":"B68","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1186\/s12864-020-06812-7","article-title":"Comparative chloroplast genome analysis of Artemisia (Asteraceae) in East Asia: insights into evolutionary divergence and phylogenomic implications","volume":"21","author":"Kim","year":"","journal-title":"BMC Genomics"},{"key":"B69","doi-asserted-by":"publisher","first-page":"39","DOI":"10.12729\/jbtr.2020.21.2.039","article-title":"Functions of flavonoids in three Korean native varieties of Artemisia species","volume":"21","author":"Kim","year":"","journal-title":"J. Biomed. Transl. Res."},{"key":"B70","doi-asserted-by":"publisher","first-page":"528","DOI":"10.11626\/kjeb.2020.38.4.528","article-title":"Floristic features of upland fields in South Korea","volume":"38","author":"Kim","year":"","journal-title":"Korean J. Environ. Biol."},{"key":"B71","doi-asserted-by":"crossref","first-page":"604","DOI":"10.7235\/HORT.20210054","article-title":"Germination conditions of Artemisia dubia seeds for factory cultivation","volume":"39","author":"Kim","year":"2021","journal-title":"Horticult. Sci. Technol"},{"key":"B72","doi-asserted-by":"publisher","first-page":"25","DOI":"10.5141\/jee.22.054","article-title":"Distribution characteristics of Manchurian and China\u2013Japan\u2013Korea flora in Korean Peninsula","volume":"46","author":"Kim","year":"2022","journal-title":"J. Ecol. Environ."},{"key":"B73","doi-asserted-by":"publisher","first-page":"2028","DOI":"10.1248\/cpb.33.2028","article-title":"Studies on the activities of tannins and related compounds from medicinal plants and drugs. VII. Effects of extracts of leaves of Artemisia species, and caffeic acid and chlorogenic acid on lipid metabolic injury in rats fed peroxidized oil","volume":"33","author":"Kimura","year":"1985","journal-title":"Chem. Pharm. Bull."},{"key":"B74","doi-asserted-by":"publisher","first-page":"2103","DOI":"10.2478\/s11756-020-00509-8","article-title":"Rocky vegetation in South Korea and their relation to the whole Korean Peninsula","volume":"75","author":"Kolbek","year":"2020","journal-title":"Biologia"},{"key":"B75","doi-asserted-by":"publisher","first-page":"232","DOI":"10.3390\/biomedicines11010232","article-title":"Artemisia annua L. extracts irreversibly inhibit the activity of CYP2B6 and CYP3A4 enzymes","volume":"11","author":"Kond\u017ea","year":"2023","journal-title":"Biomedicines"},{"key":"B76","doi-asserted-by":"publisher","first-page":"6054069","DOI":"10.1155\/2018\/6054069","article-title":"Artemisia extract suppresses NLRP3 and AIM2 inflammasome activation by inhibition of ASC phosphorylation","volume":"2018","author":"Kwak","year":"2018","journal-title":"Mediat. Inflamm."},{"key":"B77","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1007\/BF02978255","article-title":"Phytochemical constituents of Artemisia japonica ssp. littoricola","volume":"24","author":"Kwon","year":"2001","journal-title":"Archives Pharmacal Res."},{"key":"B78","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1016\/j.jep.2010.05.062","article-title":"Wormwood (Artemisia absinthium L.)--a curious plant with both neurotoxic and neuroprotective properties?","volume":"131","author":"Lachenmeier","year":"2010","journal-title":"J. Ethnopharmacol."},{"key":"B79","doi-asserted-by":"publisher","first-page":"1049209","DOI":"10.3389\/fpls.2022.1049209","article-title":"Comparative and phylogenetic analysis of complete chloroplast genomes from five Artemisia species","volume":"13","author":"Lan","year":"2022","journal-title":"Front. Plant Sci."},{"key":"B80","doi-asserted-by":"publisher","first-page":"29","DOI":"10.5147\/jaimlb.vi.257","article-title":"Comparative phylogenetic analysis of six angiosperm families using rbcL and matK chloroplast markers","author":"Leaks","year":"2025","journal-title":"J. Artif. Intell. Mach. Learn. Bioinforma."},{"key":"B81","doi-asserted-by":"publisher","first-page":"241","DOI":"10.12925\/JKOCS.2020.37.2.241","article-title":"Whitening activities of extracts of seomaeyakssuk (Artemisia argyi H.)","volume":"37","author":"Lee","year":"2020","journal-title":"J. Korean Appl. Sci. Technol."},{"key":"B82","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1248\/bpb.29.629","article-title":"Development of SCAR marker for discrimination of Artemisia princeps and A. argyi from other Artemisia herbs","volume":"29","author":"Lee","year":"2006","journal-title":"Biol. Pharm. Bull."},{"key":"B83","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1248\/bpb.31.685","article-title":"Application of the multiplex PCR method for discrimination of Artemisia iwayomogi from other Artemisia herbs","volume":"31","author":"Lee","year":"2008","journal-title":"Biol. Pharm. Bull."},{"key":"B84","doi-asserted-by":"publisher","first-page":"1912","DOI":"10.1248\/bpb.32.1912","article-title":"Molecular authentication of 21 Korean Artemisia species (Compositae) by polymerase chain reaction-restriction fragment length polymorphism based on trnL-F region of chloroplast DNA","volume":"32","author":"Lee","year":"2009","journal-title":"Biol. Pharmaceutical Bulletin"},{"key":"B85","first-page":"293","article-title":"A phylogenetic analysis of Korean Artemisia L. based on ITS sequences","volume":"23","author":"Lee","year":"2010","journal-title":"Korean J. Plant Resour."},{"key":"B86","doi-asserted-by":"publisher","first-page":"112","DOI":"10.5352\/jls.2014.24.2.112","article-title":"Effects of Rubus coreanus and Artemisia princeps extracts on the ultraviolet B-induced DNA damage responses in HaCaT cells","volume":"24","author":"Lee","year":"2014","journal-title":"J. Life Sci."},{"key":"B87","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1080\/23802359.2016.1176880","article-title":"The complete chloroplast genome sequences of Artemisia gmelinii and Artemisia capillaris (Asteraceae)","volume":"1","author":"Lee","year":"2016","journal-title":"Mitochondrial DNA B Resour."},{"key":"B88","doi-asserted-by":"publisher","first-page":"18","DOI":"10.3390\/ijms18081762","article-title":"Artemisia iwayomogi extract attenuates high-fat diet-induced hypertriglyceridemia in mice: potential involvement of the adiponectin-AMPK pathway and very low density lipoprotein assembly in the liver","volume":"18","author":"Lee","year":"","journal-title":"Int. J. Mol. Sci."},{"key":"B89","doi-asserted-by":"publisher","first-page":"7375615","DOI":"10.1155\/2017\/7375615","article-title":"Inhibitory effect of chemical constituents isolated from Artemisia iwayomogi on polyol pathway and simultaneous quantification of major bioactive compounds","volume":"2017","author":"Lee","year":"","journal-title":"BioMed Res. Int."},{"key":"B90","first-page":"647","article-title":"Crop characteristics and flavonoid contents of mugwort (Artemisia argyi H. L\u00e9v. and Vaniot)","volume":"36","author":"Lee","year":"","journal-title":"Hortic. Sci. Technol."},{"key":"B91","doi-asserted-by":"publisher","first-page":"27","DOI":"10.2478\/jas-2018-0003","article-title":"Anti-nosemosis activity of Aster scaber and Artemisia dubia aqueous extracts","volume":"62","author":"Lee","year":"","journal-title":"J. Apic. Sci."},{"key":"B92","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/s41610-017-0062-z","article-title":"Relationship between halophyte distribution and soil environmental factors in the west coast of South Korea","volume":"42","author":"Lee","year":"","journal-title":"J. Ecol. Environ."},{"key":"B93","doi-asserted-by":"publisher","first-page":"e0264576","DOI":"10.1371\/journal.pone.0264576","article-title":"Genetic and chemical markers for authentication of three Artemisia species: A. capillaris, A. gmelinii, and A. fukudo","volume":"17","author":"Lee","year":"2022","journal-title":"PLoS One"},{"key":"B94","doi-asserted-by":"publisher","first-page":"1186023","DOI":"10.3389\/fpls.2023.1186023","article-title":"Integrative analysis of metabolite and transcriptome reveals biosynthetic pathway and candidate genes for eupatilin and jaceosidin biosynthesis in Artemisia argyi","volume":"14","author":"Lee","year":"2023","journal-title":"Front. Plant Sci."},{"key":"B95","doi-asserted-by":"publisher","first-page":"118344","DOI":"10.1016\/j.jep.2024.118344","article-title":"Chemical composition of Artemisia argyi essential oil and its antifungal activity against dermatophytes by inhibiting oxidative phosphorylation and causing oxidative damage","volume":"331","author":"Li","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"B96","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1080\/23802359.2018.1450680","article-title":"The complete chloroplast genome of Artemisia hallaisanensis Nakai (Asteraceae), an endemic medicinal herb in Korea","volume":"3","author":"Lim","year":"2018","journal-title":"Mitochondrial DNA B Resour"},{"key":"B97","doi-asserted-by":"publisher","first-page":"956","DOI":"10.1080\/24701394.2016.1219729","article-title":"Evaluation of DNA barcode candidates for the discrimination of Artemisia L","volume":"28","author":"Liu","year":"2017","journal-title":"Mitochondrial DNA Part A"},{"key":"B160","doi-asserted-by":"publisher","first-page":"947512","DOI":"10.3389\/fphar.2022.947512","article-title":"Advancements and future prospective of DNA barcodes in the herbal drug industry","volume":"13","author":"Mahima","year":"2022","journal-title":"Front. Pharmacol."},{"key":"B98","doi-asserted-by":"publisher","first-page":"1531","DOI":"10.1248\/bpb.b16-00336","article-title":"DNA barcode for identifying folium Artemisiae argyi from counterfeits","volume":"39","author":"Mei","year":"2016","journal-title":"Biol. Pharmaceutical Bulletin"},{"key":"B99","doi-asserted-by":"publisher","first-page":"1902","DOI":"10.1111\/pbi.13870","article-title":"Genome sequencing reveals chromosome fusion and extensive expansion of genes related to secondary metabolism in Artemisia argyi","volume":"20","author":"Miao","year":"2022","journal-title":"Plant Biotechnol. J."},{"key":"B100","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1016\/j.jep.2009.06.001","article-title":"Inhibitory effect of eupatilin and jaceosidin isolated from Artemisia princeps on carrageenan-induced inflammation in mice","volume":"125","author":"Min","year":"2009","journal-title":"J. Ethnopharmacol."},{"key":"B101","first-page":"171","article-title":"Characterization techniques for herbal products","volume-title":"Management of High Altitude Pathophysiology","author":"Mishra","year":"2018"},{"key":"B102","doi-asserted-by":"publisher","first-page":"1359","DOI":"10.3390\/ani15101359","article-title":"The beneficial use of Artemisia annua, Artemisinin, and other compounds in animal health","volume":"15","author":"Morua","year":"2025","journal-title":"Animals"},{"key":"B3","doi-asserted-by":"publisher","first-page":"1352948","DOI":"10.1155\/2017\/1352948","article-title":"Review: DNA barcoding and chromatography fingerprints for the authentication of botanicals in herbal medicinal products","volume":"2017","author":"Mohammed Abubakar","year":"2017","journal-title":"Evid. Based Complementary Altern. Med."},{"key":"B103","doi-asserted-by":"publisher","first-page":"864728","DOI":"10.3389\/fevo.2022.864728","article-title":"Effect of altitude on volatile organic and phenolic compounds of Artemisia brevifolia Wall ex Dc. from the Western Himalayas","volume":"10","author":"Nataraj","year":"2022","journal-title":"Front. Ecol. Evol."},{"key":"B104","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1002\/pca.3466","article-title":"Integrating DNA barcoding within an orthogonal approach for herbal product authentication: a narrative review","volume":"36","author":"Nazar","year":"2024","journal-title":"Phytochem. Anal."},{"key":"B105","doi-asserted-by":"publisher","first-page":"4791","DOI":"10.1038\/s41598-024-55128-z","article-title":"Bioprospecting of Artemisia genus: from artemisinin to other potentially bioactive compounds","volume":"14","author":"Negri","year":"2024","journal-title":"Sci. Rep."},{"key":"B106","doi-asserted-by":"publisher","first-page":"1934578X19850354","DOI":"10.1177\/1934578x19850354","article-title":"Bioactive compounds and health benefits of Artemisia species","volume":"14","author":"Nigam","year":"2019","journal-title":"Nat. Product. Commun."},{"key":"B107","doi-asserted-by":"publisher","first-page":"853023","DOI":"10.3389\/fphar.2022.853023","article-title":"Advances in fingerprint analysis for standardization and quality control of herbal medicines","volume":"13","author":"Noviana","year":"2022","journal-title":"Front. Pharmacol."},{"key":"B108","doi-asserted-by":"publisher","first-page":"104996","DOI":"10.1016\/j.fitote.2021.104996","article-title":"Sesquiterpenes from Artemisia sieversiana and their anti-inflammatory activities","volume":"154","author":"Nuermaimaiti","year":"2021","journal-title":"Fitoterapia"},{"key":"B109","doi-asserted-by":"publisher","first-page":"5128","DOI":"10.3390\/molecules27165128","article-title":"Traditional use, phytochemical profiles and pharmacological properties of Artemisia genus from Central Asia","volume":"27","author":"Nurlybekova","year":"2022","journal-title":"Molecules"},{"key":"B110","first-page":"536","article-title":"Sesamin isolated from Artemisia littoricola suppresses UVA-induced changes in human dermal fibroblasts","author":"Oh","year":"2024","journal-title":"\ud55c\uad6d\uc2dd\ud488\uc601\uc591\uacfc\ud559\ud68c \ud559\uc220\ub300\ud68c\ubc1c\ud45c\uc9d1"},{"key":"B111","doi-asserted-by":"publisher","first-page":"756","DOI":"10.3389\/fphar.2018.00756","article-title":"Bioactive phenolics of the genus Artemisia (Asteraceae): HPLC-DAD-ESI-TQ-MS\/MS profile of the Siberian species and their inhibitory potential against \u03b1-amylase and \u03b1-glucosidase","volume":"9","author":"Olennikov","year":"2018","journal-title":"Front. Pharmacol."},{"key":"B112","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1111\/ics.70039","article-title":"Natural\u2010based antioxidants in cosmeceuticals: extraction, bioavailability and skin ageing applications","volume":"48","author":"Omidian","year":"2026","journal-title":"Int. J. Cosmetic Sci."},{"key":"B113","doi-asserted-by":"publisher","first-page":"e47","DOI":"10.1017\/jns.2016.41","article-title":"Flavonoids: an overview","volume":"5","author":"Panche","year":"2016","journal-title":"J. Nutrit. Sci."},{"key":"B114","doi-asserted-by":"publisher","first-page":"175","DOI":"10.11110\/kjpt.2016.46.2.175","article-title":"Taxonomic revision of the Artemisia sacrorum group","volume":"46","author":"Park","year":"2016","journal-title":"Korean J. Pl. Taxon."},{"key":"B115","first-page":"319","article-title":"Study of optimized extraction conditions for simultaneous anti-inflammatory and antioxidant activity of Artemisia iwayomogi using response surface methodology","volume":"45","author":"Park","year":"","journal-title":"J. Soc. Cosmet. Sci. Korea"},{"key":"B116","doi-asserted-by":"publisher","first-page":"433","DOI":"10.3839\/jabc.2019.059","article-title":"Analysis of polyphenolic metabolites from Artemisia gmelinii Weber ex Stechm. and regional comparison in Korea","volume":"62","author":"Park","year":"","journal-title":"J. Appl. Biol. Chem."},{"key":"B117","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1186\/s13765-024-00883-w","article-title":"Correlation analysis between artemisinin and its derivative contents and trichome characteristics from different Artemisia species","volume":"67","author":"Park","year":"2024","journal-title":"Appl. Biol. Chem."},{"key":"B118","doi-asserted-by":"publisher","first-page":"1225","DOI":"10.1055\/s-0042-111208","article-title":"DNA barcoding for the identification of botanicals in herbal medicine and dietary supplements: strengths and limitations","volume":"82","author":"Parveen","year":"2016","journal-title":"Planta Medica"},{"key":"B159","article-title":"Royal botanic gardens, kew. Species database. Use individual species pages (links below)","year":"2026","journal-title":"General Database"},{"key":"B119","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1186\/s12870-023-04295-8","article-title":"Metabolomic and transcriptomic analyses provide insights into variations in flavonoids contents between two Artemisia cultivars","volume":"23","author":"Qiao","year":"2023","journal-title":"BMC Plant Biol."},{"key":"B120","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1002\/pca.2732","article-title":"Benefits and limitations of DNA barcoding and metabarcoding in herbal product authentication","volume":"29","author":"Raclariu","year":"2017","journal-title":"Phytochem. Anal."},{"key":"B121","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1201\/9781003544418-21","article-title":"Regulatory considerations for herbal products","volume-title":"Herbal pharmacopeia: Nanotechnology and advancing drug discovery.","author":"Rahman","year":"2025"},{"key":"B122","doi-asserted-by":"publisher","first-page":"S4","DOI":"10.1186\/1475-2875-10-S1-S4","article-title":"Whole plant extracts versus single compounds for the treatment of malaria: synergy and positive interactions","volume":"10","author":"Rasoanaivo","year":"2011","journal-title":"Malar. J."},{"key":"B123","doi-asserted-by":"publisher","first-page":"1326","DOI":"10.56093\/ijans.v87i11.75861","article-title":"In vitro antioxidative potential of Artemisia indica willd","volume":"87","author":"Ruwali","year":"2017","journal-title":"Indian J. Anim. Sci."},{"key":"B124","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1111\/j.1755-263x.2010.00096.x","article-title":"Conservation\u2010reliant species and the future of conservation","volume":"3","author":"Scott","year":"2010","journal-title":"Conserv. Lett."},{"key":"B125","doi-asserted-by":"publisher","first-page":"141","DOI":"10.5141\/jefb.2010.33.2.141","article-title":"Antimicrobial activity and chemical components of two plants, Artemisia capillaris and Artemisia iwayomogi, used as Korean herbal Injin","volume":"33","author":"Seo","year":"2010","journal-title":"J. Ecol. Environ."},{"key":"B126","doi-asserted-by":"publisher","first-page":"5628601","DOI":"10.1155\/2022\/5628601","article-title":"Artemisia spp.: an update on its chemical composition, pharmacological and toxicological profiles","volume":"2022","author":"Sharifi-Rad","year":"2022","journal-title":"Oxidative Med. Cell. Longev."},{"key":"B127","doi-asserted-by":"publisher","first-page":"1330","DOI":"10.3390\/molecules22081330","article-title":"Complete chloroplast genome sequence and phylogenetic analysis of the medicinal plant Artemisia annua","volume":"22","author":"Shen","year":"2017","journal-title":"Molecules"},{"key":"B128","doi-asserted-by":"publisher","first-page":"885622","DOI":"10.3389\/fpls.2022.885622","article-title":"Basic helix-loop-helix transcription factors AabHLH2 and AabHLH3 function antagonistically with AaMYC2 and are negative regulators in artemisinin biosynthesis","volume":"13","author":"Shen","year":"2022","journal-title":"Front. Plant Sci."},{"key":"B129","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1186\/s12906-022-03536-x","article-title":"Artemisia argyi extract alleviates inflammation in a DSS-induced colitis mouse model and enhances immunomodulatory effects in lymphoid tissues","volume":"22","author":"Shin","year":"2022","journal-title":"BMC Complementary Med. Ther."},{"key":"B130","doi-asserted-by":"publisher","first-page":"613","DOI":"10.3390\/metabo13050613","article-title":"Secondary metabolites isolated from Artemisia afra and Artemisia annua and their anti-malarial, anti-inflammatory and immunomodulating properties\u2014Pharmacokinetics and pharmacodynamics: a review","volume":"13","author":"Shinyuy","year":"2023","journal-title":"Metabolites"},{"key":"B131","doi-asserted-by":"publisher","first-page":"1954","DOI":"10.3390\/plants11151954","article-title":"Chemical constituents from the aerial parts of Artemisia iwayomogi and their anti-neuroinflammatory activities","volume":"11","author":"Son","year":"2022","journal-title":"Plants"},{"key":"B132","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1016\/j.japb.2025.04.004","article-title":"An updated checklist of the vascular flora native to Korea","volume":"18","author":"Son","year":"2025","journal-title":"J. Asia-Pacific Biodivers."},{"key":"B133","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1002\/bmc.3587","article-title":"Polyphenolic profile and antioxidant effects of various parts of Artemisia annua L","volume":"30","author":"Song","year":"2016","journal-title":"Biomed. Chromatogr."},{"key":"B134","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1007\/s00204-015-1471-3","article-title":"Hepatotoxicity of herbal and dietary supplements: an update","volume":"89","author":"Stickel","year":"2015","journal-title":"Archives Toxicol."},{"key":"B135","first-page":"218","article-title":"Phylogenetic analysis of Artemisia spp. by morphological characteristics of reproductive organs in Korea","volume":"16","author":"Sung","year":"2008","journal-title":"Korean J. Med. Crop Sci."},{"key":"B136","doi-asserted-by":"publisher","first-page":"1411","DOI":"10.1016\/j.febslet.2006.01.065","article-title":"Artemisia annua L. (Asteraceae) trichome-specific cDNAs reveal CYP71AV1, a cytochrome P450 with a key role in the biosynthesis of the antimalarial sesquiterpene lactone artemisinin","volume":"580","author":"Teoh","year":"2006","journal-title":"FEBS Letters"},{"key":"B137","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1139\/b09-032","article-title":"Molecular cloning of an aldehyde dehydrogenase implicated in artemisinin biosynthesis in Artemisia annua. This paper is one of a selection of papers published in a Special Issue from the National Research Council of Canada \u2013 plant Biotechnology Institute","volume":"87","author":"Teoh","year":"2009","journal-title":"Botany"},{"key":"B138","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1089\/109662004322984707","article-title":"Inhibitory effects of polyphenols in leaves of Artemisia princeps PAMP on protein fragmentation by Cu(II)-H2O2 in vitro","volume":"7","author":"Toda","year":"2004","journal-title":"J. Med. Food"},{"key":"B139","doi-asserted-by":"publisher","first-page":"1056","DOI":"10.1111\/j.1742-1241.2012.03008.x","article-title":"Evaluation of documented drug interactions and contraindications associated with herbs and dietary supplements: a systematic literature review","volume":"66","author":"Tsai","year":"2012","journal-title":"Int. J. Clin. Pract."},{"key":"B140","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1186\/1471-2164-10-465","article-title":"Global characterization of Artemisia annua glandular trichome transcriptome using 454 pyrosequencing","volume":"10","author":"Wang","year":"2009","journal-title":"BMC Genomics"},{"key":"B141","doi-asserted-by":"publisher","first-page":"135198","DOI":"10.1016\/j.foodchem.2022.135198","article-title":"In vitro antioxidant analysis of flavonoids extracted from Artemisia argyi stem and their anti-inflammatory activity in lipopolysaccharide-stimulated RAW 264.7 macrophages","volume":"407","author":"Wang","year":"","journal-title":"Food Chem."},{"key":"B142","doi-asserted-by":"publisher","first-page":"6809","DOI":"10.3390\/ijms24076809","article-title":"Moisturizing and antioxidant effects of Artemisia argyi essence liquid in HaCaT keratinocytes","volume":"24","author":"Wang","year":"","journal-title":"Int. J. Mol. Sci."},{"key":"B143","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1186\/s12864-024-10455-3","article-title":"Comparative and phylogenetic analysis of the complete chloroplast genomes of 10 Artemisia selengensis resources based on high-throughput sequencing","volume":"25","author":"Wang","year":"2024","journal-title":"BMC Genomics"},{"key":"B144","doi-asserted-by":"publisher","first-page":"875","DOI":"10.3732\/ajb.1300329","article-title":"Flower morphology and floral sequence in Artemisia annua (Asteraceae)","volume":"101","author":"Wetzstein","year":"2014","journal-title":"Am. J. Bo."},{"key":"B145","volume-title":"WHO Guidelines on Safety Monitoring of Herbal Medicines in Pharmacovigilance Systems","author":"World Health","year":"2004"},{"key":"B146","doi-asserted-by":"publisher","first-page":"806","DOI":"10.3390\/nu10070806","article-title":"Ethanolic extracts of Artemisia apiacea Hance improved atopic dermatitis-like skin lesions in vivo and suppressed TNF-Alpha\/IFN-Gamma-induced proinflammatory chemokine production in vitro","volume":"10","author":"Yang","year":"2018","journal-title":"Nutrients"},{"key":"B147","doi-asserted-by":"publisher","first-page":"bbac485","DOI":"10.1093\/bib\/bbac485","article-title":"From single-to multi-omics: future research trends in medicinal plants","volume":"24","author":"Yang","year":"2022","journal-title":"Briefings Bioinforma."},{"key":"B148","doi-asserted-by":"publisher","DOI":"10.1016\/j.japb.2025.10.001","article-title":"Seed dormancy types in 129 native Asteraceae from Korea: focus on non-deep physiological dormancy","author":"Yong","year":"2025","journal-title":"J. Asia-Pacific Biodivers."},{"key":"B149","first-page":"235","article-title":"Anti-oxidant activities and anti-inflammatory effects on Artemisia scoparia","volume":"37","author":"Yoon","year":"2006","journal-title":"Korean J. Pharmacogn."},{"key":"B150","doi-asserted-by":"publisher","first-page":"531","DOI":"10.3892\/ijmm.2011.620","article-title":"An active part of Artemisia sacrorum Ledeb. inhibits adipogenesis via the AMPK signaling pathway in 3T3-L1 adipocytes","volume":"27","author":"Yuan","year":"2011","journal-title":"Int. Journal Molecular Medicine"},{"key":"B151","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1111\/pbi.14449","article-title":"AaMYC3 bridges the regulation of glandular trichome density and artemisinin biosynthesis in Artemisia annua","volume":"23","author":"Yuan","year":"2024","journal-title":"Plant Biotechnol. J."},{"key":"B152","doi-asserted-by":"publisher","first-page":"1","DOI":"10.53797\/aseana.v5i2.1.2025","article-title":"Development strategies for Artemisia cultivation in Indonesia","volume":"5","author":"Yuliani","year":"2025","journal-title":"ASEANA Sci. Educ. J."},{"key":"B153","first-page":"1","article-title":"In situ and ex situ conservation: complementary approaches for maintaining biodiversity","volume":"4","author":"Zegeye","year":"2017","journal-title":"Int. J. Res. Environ. Stud."},{"key":"B154","doi-asserted-by":"publisher","first-page":"1281","DOI":"10.1016\/j.fitote.2012.05.016","article-title":"3,5-Dicaffeoylquinic acid isolated from Artemisia argyi and its ester derivatives exert anti-Leucyl-tRNA synthetase of Giardia lamblia (GlLeuRS) and potential anti-giardial effects","volume":"83","author":"Zhang","year":"2012","journal-title":"Fitoterapia"},{"key":"B155","doi-asserted-by":"publisher","first-page":"100611","DOI":"10.1016\/j.xplc.2023.100611","article-title":"Chloroplast gene expression: recent advances and perspectives","volume":"4","author":"Zhang","year":"2023","journal-title":"Plant Commun."},{"key":"B156","doi-asserted-by":"publisher","first-page":"e14461","DOI":"10.1111\/ppl.14461","article-title":"Artemisia annua ZFP8L regulates glandular trichome development","volume":"176","author":"Zhang","year":"2024","journal-title":"Physiol. Plant"},{"key":"B157","doi-asserted-by":"publisher","first-page":"0","DOI":"10.48130\/mpb-0024-0018","article-title":"Glandular trichomes: the factory of artemisinin biosynthesis","volume":"3","author":"Zhao","year":"2024","journal-title":"Med. Plant Biol."},{"key":"B158","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1186\/s13020-022-00655-y","article-title":"DNA barcoding: An efficient technology to authenticate plant species of traditional Chinese medicine and recent advances","volume":"17","author":"Zhu","year":"2022","journal-title":"Chin. Med."}],"container-title":["Frontiers in Pharmacology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fphar.2026.1873437\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T05:32:46Z","timestamp":1789536766000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fphar.2026.1873437\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,16]]},"references-count":160,"alternative-id":["10.3389\/fphar.2026.1873437"],"URL":"https:\/\/doi.org\/10.3389\/fphar.2026.1873437","relation":{},"ISSN":["1663-9812"],"issn-type":[{"value":"1663-9812","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,16]]},"article-number":"1873437"}}