{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T15:16:03Z","timestamp":1786115763915,"version":"build-2736575974"},"reference-count":15,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T00:00:00Z","timestamp":1785974400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Pharmacol."],"abstract":"<jats:p>The incidence of copper sulfate poisoning varies across different regions. It is relatively rare in Western countries but more prevalent in South Asian nations, accounting for approximately 40% of all heavy metal poisoning cases. The majority of affected individuals are rural residents, with a mortality rate ranging from 14% to 36%. Copper sulfate poisoning often leads to gastrointestinal corrosion, intravascular hemolysis, hemolytic anemia, methemoglobinemia, and acute multi-organ dysfunction, often resulting in death due to delayed treatment. In June 2024, we successfully managed a case of acute oral copper sulfate poisoning through early interventions, including gastric lavage and sodium dimercaptopropane sulfonate (Na-DMPS) for copper chelation, resulting in the patient\u2019s recovery and discharge after 1\u00a0week.<\/jats:p>","DOI":"10.3389\/fphar.2026.1879318","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T05:33:39Z","timestamp":1785994419000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Successful treatment of acute oral copper sulfate poisoning: a case report"],"prefix":"10.3389","volume":"17","author":[{"given":"Yingxin","family":"Zhao","sequence":"first","affiliation":[{"name":"Tianjin Medical University General Hospital","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruifang","family":"Li","sequence":"additional","affiliation":[{"name":"Tianjin Medical University General Hospital","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenguang","family":"Wang","sequence":"additional","affiliation":[{"name":"Tianjin Medical University General Hospital","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Li","sequence":"additional","affiliation":[{"name":"Tianjin Medical University General Hospital","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijun","family":"Wang","sequence":"additional","affiliation":[{"name":"Tianjin Medical University General Hospital","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,8,6]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/j.jtemb.2016.03.013","article-title":"A review of pitfalls and progress in chelation treatment of metal poisonings","volume":"38","author":"Andersen","year":"2016","journal-title":"J. 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