{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T07:49:24Z","timestamp":1758268164837,"version":"3.41.2"},"reference-count":35,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,6,5]],"date-time":"2020-06-05T00:00:00Z","timestamp":1591315200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Physiol."],"DOI":"10.3389\/fphys.2020.00553","type":"journal-article","created":{"date-parts":[[2020,6,5]],"date-time":"2020-06-05T13:34:07Z","timestamp":1591364047000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Differential Responses of Liver and Hypothalamus to the Nutritional Condition During Lactation and Adult Life"],"prefix":"10.3389","volume":"11","author":[{"given":"Isabela Ramos","family":"Mariano","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"La\u00eds Akemi","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renan","family":"Soares Rabassi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa Lara","family":"Rissi Sabino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camila","family":"Bataglini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia Carla Santana Ferreira","family":"Azevedo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ros\u00e2ngela Fernandes","family":"Garcia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Montserrat Diaz","family":"Pedrosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2020,6,5]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1016\/j.mito.2013.08.011","article-title":"Enzymes involved in L-lactate metabolism in humans.","volume":"13","author":"Adeva","year":"2013","journal-title":"Mitochondrion"},{"key":"B2","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1016\/j.ebiom.2018.11.048","article-title":"The partial inhibition of hypothalamic IRX3 exacerbates obesity.","volume":"39","author":"Araujo","year":"2018","journal-title":"EBiomedicine"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/969137","article-title":"Sustained liver glucose release in response to adrenaline can improve hypoglycaemic episodes in rats under food restriction subjected to acute exercise.","volume":"2014","author":"Babata","year":"2014","journal-title":"J. Endocrinol."},{"key":"B4","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1080\/13813455.2016.1273364","article-title":"Glutamine dipeptide and cortisol change the liver glucose metabolism and reduce the severity of insulin-induced hypoglycaemia in untreated T1DM Swiss mice.","volume":"123","author":"Bataglini","year":"2017","journal-title":"Arch. Physiol. Biochem."},{"key":"B5","doi-asserted-by":"publisher","first-page":"S19","DOI":"10.1039\/ijosup.2012.17","article-title":"Nutritional programming of hypothalamic development: critical periods and windows of opportunity.","volume":"2","author":"Bouret","year":"2012","journal-title":"Int. J. Obse. Suppl."},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1201\/9781315120171-7","article-title":"Development of hypothalamic circuits that control food intake and energy balance","author":"Bouret","year":"2017","journal-title":"Appetite and Food Intake: Central Control"},{"key":"B7","doi-asserted-by":"publisher","first-page":"840","DOI":"10.1523\/JNEUROSCI.3215-12.2013","article-title":"Neonatal leptin exposure specifies innervation of presympathetic hypothalamic neurons and improves the metabolic status of leptin-deficient mice.","volume":"33","author":"Bouyer","year":"2013","journal-title":"J. Neurosci."},{"key":"B8","first-page":"1446","article-title":"Pyruvate, phosphoenolpyruvate and D-glycerate-2-phosphate","author":"Czok","year":"1974","journal-title":"Methods of Enzymatic Analysis"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmet.2016.01.003","article-title":"Postnatal undernutrition delays a key step in the maturation of hypothalamic feeding circuits.","volume":"5","author":"De Solis","year":"2016","journal-title":"Mol. Metab."},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.38704","article-title":"Insulin regulates POMC neuronal plasticity to control glucose metabolism.","volume":"2018","author":"Dodd","year":"2018","journal-title":"eLife"},{"key":"B11","doi-asserted-by":"publisher","first-page":"R1104","DOI":"10.1152\/ajpregu.1991.260.6.r1104","article-title":"Intake and use of milk nutrients by rat pups suckled in small, medium, or large litters.","volume":"260","author":"Fiorotto","year":"1991","journal-title":"Am. J. Physiol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1080\/13813455.2017.1370000","article-title":"Refeeding after caloric restriction reverses altered liver glucose release.","volume":"124","author":"Garcia","year":"2017","journal-title":"Arch. Physiol. Biochem."},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.007.8262","article-title":"Zonation of nitrogen and glucose metabolism gene expression upon acute liver damage in mouse.","volume":"8","author":"Ghafoory","year":"2013","journal-title":"PLoS One"},{"key":"B14","first-page":"1464","article-title":"L-(+)-Lactate. Determination with lactate dehydrogenase and NAD","author":"Gutmann","year":"1974","journal-title":"Methods of Enzymatic Analysis"},{"key":"B15","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/0006-8993(93)91771-j","article-title":"Corticotropin-releasing factor in the paraventricular nucleus modulates feeding induced by neuropeptide Y.","volume":"611","author":"Heinrichs","year":"1993","journal-title":"Brain Res."},{"key":"B16","doi-asserted-by":"publisher","first-page":"185","DOI":"10.2174\/157339907781368995","article-title":"Sympathetic mechanisms of hypoglycemic counterregulation.","volume":"3","author":"Hoffman","year":"2007","journal-title":"Curr. Diabetes Rev."},{"key":"B17","doi-asserted-by":"crossref","DOI":"10.1007\/1-4020-3535-7","author":"Koletzko","year":"2005","journal-title":"Early Nutrition and its Later Consequences: New Opportunities."},{"key":"B18","doi-asserted-by":"publisher","first-page":"1487","DOI":"10.1093\/jn\/128.9.1487","article-title":"Opposite fluxes of glutamine and alanine in the splanchnic area are an efficient mechanism for nitrogen sparing in rats.","volume":"128","author":"Lopez","year":"1998","journal-title":"J. Nutr."},{"key":"B19","doi-asserted-by":"publisher","first-page":"626","DOI":"10.1016\/j.nutres.2010.08.003","article-title":"Insulin sensitivity and liver glucose production in the rat are influenced by lifetime food restriction.","volume":"30","author":"Malta","year":"2010","journal-title":"Nutr. Res."},{"key":"B20","first-page":"55","article-title":"Desenvolvimento corporal e adiposidade de ratos Wistar submetidos a diferentes regimes alimentares.","volume":"14","author":"Malta","year":"2010","journal-title":"Arq. Ci\u00eancias Sa\u00fade UNIPAR"},{"key":"B21","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/s0149-7634(00)00047-6","article-title":"The regulation of total body fat: lessons learned from lipectomy studies.","volume":"25","author":"Mauer","year":"2001","journal-title":"Neurosci. Beobehav. Rev."},{"key":"B22","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1530\/eje.0.1380240","article-title":"Autoregulation of hepatic glucose production.","volume":"138","author":"Moore","year":"1998","journal-title":"Eur. J. Encocrinol."},{"key":"B23","doi-asserted-by":"publisher","first-page":"875","DOI":"10.1093\/nutria\/nuy046","article-title":"Leptin as a breast milk component for the prevention of obesity.","volume":"76","author":"Palou","year":"2018","journal-title":"Nutr. Res."},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2013.00130","article-title":"Stress induced obesity: lessons from rodent models of stress.","volume":"7","author":"Patterson","year":"2013","journal-title":"Front. Neuroendocrinol."},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2012.00436","article-title":"Metabolic programming of obesity by energy restriction during the perinatal period: different outcomes depending on gender and period, type and severity of restriction.","volume":"3","author":"Pic\u00f3","year":"2012","journal-title":"Front. Physiol."},{"key":"B26","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1111\/j.1749-6632.2002.tb4292.x","article-title":"Increased fat intake, impaired fat oxidation, and failure of fat cell proliferation result in ectopic fat storage, insulin resistance, and type 2 diabetes mellitus.","volume":"967","author":"Ravussin","year":"2002","journal-title":"Ann. N.Y. Acad. Sci."},{"key":"B27","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1210\/er.2009-0028","article-title":"Developmental programming of energy balance and its hypothalamic regulation.","volume":"32","author":"Remmers","year":"2011","journal-title":"Endocr. Res."},{"key":"B28","doi-asserted-by":"publisher","first-page":"12861","DOI":"10.1073\/pnas.0702509104","article-title":"Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1.","volume":"104","author":"Rodgers","year":"2007","journal-title":"PNAS"},{"key":"B29","doi-asserted-by":"publisher","first-page":"177","DOI":"10.102\/cphy.c130024","article-title":"Energy metabolism in the liver.","volume":"4","author":"Rui","year":"2014","journal-title":"Compr. Physiol."},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms15259","article-title":"Neuronal control of peripheral insulin sensitivity and glucose metabolism.","volume":"8","author":"Ruud","year":"2017","journal-title":"Nat. Commun."},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2013.00109","article-title":"Perinatal programming of neuroendocrine mechanisms connecting feeding behavior and stress.","volume":"7","author":"Spencer","year":"2013","journal-title":"Front. Neurosci."},{"key":"B32","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1016\/bs.pmbts.2015.07.010","article-title":"Exercise and the regulation of hepatic metabolism.","volume":"135","author":"Trefts","year":"2015","journal-title":"Prog. Mol. Biol. Transl. Sci."},{"key":"B33","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1590\/s1516-891320110001000009","article-title":"Blood glucose regulation during fasting in rats under food restriction since birth.","volume":"54","author":"Vitoriano","year":"2011","journal-title":"Braz. Arch. Biol. Technol."},{"key":"B34","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1146\/annurev.nutr.27.061406.093","article-title":"Splanchnic regulation of glucose production.","volume":"27","author":"Wahren","year":"2007","journal-title":"Annu. Rev. Nutr."},{"key":"B35","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1093\/ajcn\/85.1.102","article-title":"FABP2 Ala54Thr genotype is associates with glucoregulatory function and lipid oxidation after a high-fat meal in sedentary men and women.","volume":"85","author":"Weiss","year":"2007","journal-title":"Am. J. Clin. Nutr."}],"container-title":["Frontiers in Physiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fphys.2020.00553\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,5]],"date-time":"2020-06-05T13:34:09Z","timestamp":1591364049000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fphys.2020.00553\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,5]]},"references-count":35,"alternative-id":["10.3389\/fphys.2020.00553"],"URL":"https:\/\/doi.org\/10.3389\/fphys.2020.00553","relation":{},"ISSN":["1664-042X"],"issn-type":[{"type":"electronic","value":"1664-042X"}],"subject":[],"published":{"date-parts":[[2020,6,5]]},"article-number":"553"}}