{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T06:49:31Z","timestamp":1773816571959,"version":"3.50.1"},"reference-count":36,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,6,17]],"date-time":"2020-06-17T00:00:00Z","timestamp":1592352000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000912","name":"March of Dimes Foundation","doi-asserted-by":"publisher","award":["21-FY15-138"],"award-info":[{"award-number":["21-FY15-138"]}],"id":[{"id":"10.13039\/100000912","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Physiol."],"DOI":"10.3389\/fphys.2020.00623","type":"journal-article","created":{"date-parts":[[2020,6,17]],"date-time":"2020-06-17T05:24:08Z","timestamp":1592371448000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":17,"title":["Healing Mechanism of Ruptured Fetal Membrane"],"prefix":"10.3389","volume":"11","author":[{"given":"Haruta","family":"Mogami","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. Ann","family":"Word","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2020,6,17]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1016\/j.cell.2006.02.015","article-title":"Pathogen recognition and innate immunity","volume":"124","author":"Akira","year":"2006","journal-title":"Cell"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1146\/annurev-chembioeng-061010-114257","article-title":"Tissue engineering and regenerative medicine: history, progress, and challenges","volume":"2","author":"Berthiaume","year":"2011","journal-title":"Annu. Rev. Chem. Biomol. Eng."},{"key":"ref3","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1067\/mob.2000.108872","article-title":"Outcome of pregnancies complicated by ruptured membranes after genetic amniocentesis","volume":"183","author":"Borgida","year":"2000","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref4","doi-asserted-by":"publisher","first-page":"S21","DOI":"10.1016\/j.placenta.2015.10.012","article-title":"IFPA senior award lecture: mammalian fetal membranes","volume":"48","author":"Carter","year":"2016","journal-title":"Placenta"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1038\/nrm3541","article-title":"The role of transcription-independent damage signals in the initiation of epithelial wound healing","volume":"14","author":"Cordeiro","year":"2013","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"ref6","doi-asserted-by":"publisher","first-page":"1730","DOI":"10.1093\/humrep\/14.7.1730","article-title":"Closure techniques for fetoscopic access sites in the rabbit at mid-gestation","volume":"14","author":"Deprest","year":"1999","journal-title":"Hum. Reprod."},{"key":"ref7","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1093\/molehr\/6.5.479","article-title":"Matrix metalloproteinases-2 and -9 and their endogenous tissue inhibitors in fetal membrane repair following fetoscopy in a rabbit model","volume":"6","author":"Devlieger","year":"","journal-title":"Mol. Hum. Reprod."},{"key":"ref8","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1016\/s0301-2115(00)00439-5","article-title":"An organ-culture for in vitro evaluation of fetal membrane healing capacity","volume":"92","author":"Devlieger","year":"","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"key":"ref9","doi-asserted-by":"publisher","first-page":"265sr6","DOI":"10.1126\/scitranslmed.3009337","article-title":"Wound repair and regeneration: mechanisms, signaling, and translation","volume":"6","author":"Eming","year":"2014","journal-title":"Sci. Transl. Med."},{"key":"ref10","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1515\/JPM.2007.101","article-title":"The calcium binding protein, S100B, is increased in the amniotic fluid of women with intra-amniotic infection\/inflammation and preterm labor with intact or ruptured membranes","volume":"35","author":"Friel","year":"2007","journal-title":"J. Perinat. Med."},{"key":"ref11","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1016\/j.immuni.2010.05.007","article-title":"Alternative activation of macrophages: mechanism and functions","volume":"32","author":"Gordon","year":"2010","journal-title":"Immunity"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"1284","DOI":"10.1126\/science.1204351","article-title":"Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation","volume":"332","author":"Jenkins","year":"2011","journal-title":"Science"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"1024","DOI":"10.1016\/0002-9378(90)91117-U","article-title":"Cases with ruptured membranes that \"reseal\"","volume":"163","author":"Johnson","year":"1990","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref14","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1038\/nri2215","article-title":"How dying cells alert the immune system to danger","volume":"8","author":"Kono","year":"2008","journal-title":"Nat. Rev. Immunol."},{"key":"ref15","doi-asserted-by":"publisher","first-page":"995","DOI":"10.1016\/S0002-9378(99)70338-8","article-title":"Gelatin sponge plug to seal fetoscopy port sites: technique in ovine and primate models","volume":"181","author":"Luks","year":"1999","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref16","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1038\/nbt1055","article-title":"Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering","volume":"23","author":"Lutolf","year":"2005","journal-title":"Nat. Biotechnol."},{"key":"ref18","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1053\/j.semperi.2017.07.012","article-title":"Preterm prelabor rupture of the membranes: a disease of the fetal membranes","volume":"41","author":"Menon","year":"2017","journal-title":"Semin. Perinatol."},{"key":"ref19","doi-asserted-by":"publisher","first-page":"13139","DOI":"10.1038\/s41598-017-13296-1","article-title":"Healing of preterm ruptured fetal membranes","volume":"7","author":"Mogami","year":"2017","journal-title":"Sci. Rep."},{"key":"ref20","doi-asserted-by":"publisher","first-page":"696","DOI":"10.1038\/s41598-017-18787-9","article-title":"Collagen type 1 accelerates healing of ruptured fetal membranes","volume":"8","author":"Mogami","year":"2018","journal-title":"Sci. Rep."},{"key":"ref21","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1038\/nri3073","article-title":"Protective and pathogenic functions of macrophage subsets","volume":"11","author":"Murray","year":"2011","journal-title":"Nat. Rev. Immunol."},{"key":"ref22","doi-asserted-by":"publisher","first-page":"R277","DOI":"10.1530\/REP-16-0453","article-title":"Sterile inflammation and pregnancy complications: a review","volume":"152","author":"Nadeau-Vallee","year":"2016","journal-title":"Reproduction"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1016\/S0002-9378(98)70527-7","article-title":"Fetal membrane closure techniques after hysteroamniotomy in the midgestational rabbit model","volume":"178","author":"Papadopulos","year":"1998","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref24","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1056\/NEJM199803053381006","article-title":"Premature rupture of the fetal membranes","volume":"338","author":"Parry","year":"1998","journal-title":"N. Engl. J. Med."},{"key":"ref25","doi-asserted-by":"publisher","first-page":"1852","DOI":"10.1038\/sj.jid.5701232","article-title":"IL-10 overexpression decreases inflammatory mediators and promotes regenerative healing in an adult model of scar formation","volume":"128","author":"Peranteau","year":"2008","journal-title":"J. Invest. Dermatol."},{"key":"ref26","doi-asserted-by":"publisher","first-page":"2004","DOI":"10.1016\/j.ajpath.2018.05.019","article-title":"Proliferative, migratory, and transition properties reveal metastate of human amnion cells","volume":"188","author":"Richardson","year":"2018","journal-title":"Am. J. Pathol."},{"key":"ref27","doi-asserted-by":"publisher","first-page":"eaay1486","DOI":"10.1126\/scisignal.aay1486","article-title":"Reversible EMT and MET mediate amnion remodeling during pregnancy and labor","volume":"13","author":"Richardson","year":"2020","journal-title":"Sci. Signal."},{"key":"ref28","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1111\/aji.12296","article-title":"Prevalence and clinical significance of sterile intra-amniotic inflammation in patients with preterm labor and intact membranes","volume":"72","author":"Romero","year":"2014","journal-title":"Am. J. Reprod. Immunol."},{"key":"ref29","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1016\/S0002-9378(88)80030-9","article-title":"Intraamniotic infection and the onset of labor in preterm premature rupture of the membranes","volume":"159","author":"Romero","year":"1988","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref30","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1126\/science.aad9272","article-title":"Developing a pro-regenerative biomaterial scaffold microenvironment requires T helper 2 cells","volume":"352","author":"Sadtler","year":"2016","journal-title":"Science"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"9048","DOI":"10.1016\/j.biomaterials.2013.08.017","article-title":"The effect of bioengineered acellular collagen patch on cardiac remodeling and ventricular function post myocardial infarction","volume":"34","author":"Serpooshan","year":"2013","journal-title":"Biomaterials"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"234ra58","DOI":"10.1126\/scitranslmed.3008085","article-title":"An acellular biologic scaffold promotes skeletal muscle formation in mice and humans with volumetric muscle loss","volume":"6","author":"Sicari","year":"2014","journal-title":"Sci. Transl. Med."},{"key":"ref33","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1146\/annurev-cellbio-092910-154251","article-title":"Wound repair: toward understanding and integration of single-cell and multicellular wound responses","volume":"27","author":"Sonnemann","year":"2011","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"ref34","first-page":"240","article-title":"The response of rat fetal membranes to injury","volume":"51","author":"Sopher","year":"1972","journal-title":"Ann. R Coll. Surg. Engl."},{"key":"ref35","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1038\/nature15372","article-title":"Epicardial FSTL1 reconstitution regenerates the adult mammalian heart","volume":"525","author":"Wei","year":"2015","journal-title":"Nature"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"1908","DOI":"10.3389\/fimmu.2017.01908","article-title":"S100 proteins as an important regulator of macrophage inflammation","volume":"8","author":"Xia","year":"2017","journal-title":"Front. Immunol."},{"key":"ref37","doi-asserted-by":"publisher","first-page":"596","DOI":"10.5167\/uzh-5256","article-title":"Bioengineering of foetal membrane repair","volume":"138","author":"Zisch","year":"2008","journal-title":"Swiss Med. Wkly."}],"container-title":["Frontiers in Physiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fphys.2020.00623\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,17]],"date-time":"2020-06-17T05:24:11Z","timestamp":1592371451000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fphys.2020.00623\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,17]]},"references-count":36,"alternative-id":["10.3389\/fphys.2020.00623"],"URL":"https:\/\/doi.org\/10.3389\/fphys.2020.00623","relation":{},"ISSN":["1664-042X"],"issn-type":[{"value":"1664-042X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,17]]},"article-number":"623"}}