{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T07:33:51Z","timestamp":1773732831473,"version":"3.50.1"},"reference-count":93,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,12,11]],"date-time":"2020-12-11T00:00:00Z","timestamp":1607644800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010014","name":"Manchester Metropolitan University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010014","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Physiol."],"abstract":"<jats:p><jats:bold>Rationale:<\/jats:bold> The COVID-19 pandemic is limiting outdoor and community-based activities, especially for older adults owing to the requirement for self-isolation, potentially increasing prolonged sedentary behavior (SB). Given a poor tolerance for intense exercise, SB displacement with light intensity physical activity (LIPA) is a promising health enhancing alternative. Therefore, the aims of this study were to investigate the effects of two different types of SB displacement on health outcomes in older adults and any differential impact of associated LIPA pattern.<\/jats:p><jats:p><jats:bold>Method:<\/jats:bold> 28 older women (age: 73 \u00b1 5 years, height: 1.60 \u00b1 0.07 m, weight: 67 \u00b1 10 kg, and BMI: 26.1 \u00b1 3.6 kg\/m<jats:sup>2<\/jats:sup>) underwent overnight fasted dual energy x-ray absorptiometry (DEXA) imaging, blood sampling, and functional assessments before being randomly allocated to one of two groups: (1) single continuous bout of 45\u201350 min LIPA daily (<jats:italic>n<\/jats:italic> = 14); or (2) SB fragmentation (SBF; ~48 min LIPA daily, 2 min LIPA for every 30 min of SB; <jats:italic>n<\/jats:italic> = 14). Compliance was systematically monitored using tri-axial accelerometery. All measures were taken at weeks 0 and 8.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Physical behavior significantly altered (decreased SB\/increased LIPA; <jats:italic>p<\/jats:italic> &amp;lt; 0.05) and to a similar extent in both groups. We observed a significant reduction in serum triglycerides [<jats:italic>p<\/jats:italic> = 0.045, effect size (<jats:italic>\u0273<jats:sub>p<\/jats:sub><\/jats:italic><jats:sup>2<\/jats:sup>) = 0.15; SBF: \u22120.26 \u00b1 0.77 mmol\/L, LIPA: \u22120.26 \u00b1 0.51 mmol\/L], improved 30 s sit-to-stand (STS) count (<jats:italic>p<\/jats:italic> = 0.002, <jats:italic>\u0273<jats:sub>p<\/jats:sub><\/jats:italic><jats:sup>2<\/jats:sup> = 0.32, 2 \u00b1 3 STS) and speed (<jats:italic>p<\/jats:italic> = 0.009, <jats:italic>\u0273<jats:sub>p<\/jats:sub><\/jats:italic><jats:sup>2<\/jats:sup> = 0.35, \u221210 \u00b1 33%), as well as increased average handgrip strength (<jats:italic>p<\/jats:italic> = 0.001, <jats:italic>\u0273<jats:sub>p<\/jats:sub><\/jats:italic><jats:sup>2<\/jats:sup> = 0.45, 6 \u00b1 12%), and gait speed (<jats:italic>p<\/jats:italic> = 0.005, <jats:italic>\u0273<jats:sub>p<\/jats:sub><\/jats:italic><jats:sup>2<\/jats:sup> = 0.27, 0.09 \u00b1 0.16 m\/s) in both groups. Interestingly, SBF caused a greater increase in peak handgrip strength (8 \u00b1 14%), compared to LIPA (2 \u00b1 10%; <jats:italic>p<\/jats:italic> = 0.04, <jats:italic>\u0273<jats:sub>p<\/jats:sub><\/jats:italic><jats:sup>2<\/jats:sup> = 0.38).<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> SB displacement induced significant improvements in fasting triglycerides, gait speed, as-well as STS endurance\/speed in older women. Frequent vs. continuous SB displacement also caused greater increases in handgrip strength. While both SB displacement protocols display promise as efficacious home-based interventions for self-isolating older adults, our results would suggest a physical functioning advantage of the SBF protocol for certain outcomes.<\/jats:p>","DOI":"10.3389\/fphys.2020.574595","type":"journal-article","created":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T07:26:18Z","timestamp":1607585178000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":12,"title":["The Effects of Displacing Sedentary Behavior With Two Distinct Patterns of Light Activity on Health Outcomes in Older Adults (Implications for COVID-19 Quarantine)"],"prefix":"10.3389","volume":"11","author":[{"given":"Dale","family":"Grant","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Tomlinson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kostas","family":"Tsintzas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petra","family":"Koli\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gladys Leopoldine","family":"Onambele-Pearson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2020,12,11]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.archger.2011.02.006","article-title":"Validity and usefulness of hand-held dynamometry for measuring muscle strength in community-dwelling older persons","volume":"54","author":"Abizanda","year":"2012","journal-title":"Arch. 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