{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:16:36Z","timestamp":1753892196174,"version":"3.41.2"},"reference-count":49,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,11,2]],"date-time":"2020-11-02T00:00:00Z","timestamp":1604275200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007683","name":"Nihon University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007683","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Physiol."],"DOI":"10.3389\/fphys.2020.598451","type":"journal-article","created":{"date-parts":[[2020,11,2]],"date-time":"2020-11-02T05:12:16Z","timestamp":1604293936000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Antioxidative Potency of Dolphin Serum Albumin Is Stronger Than That of Human Serum Albumin Irrespective of Substitution of 34Cysteine With Serine"],"prefix":"10.3389","volume":"11","author":[{"given":"Miwa","family":"Suzuki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Anraku","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wataru","family":"Hakamata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takushi","family":"Kishida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiichi","family":"Ueda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoko","family":"Endoh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2020,11,2]]},"reference":[{"key":"B1","doi-asserted-by":"crossref","first-page":"24845","DOI":"10.1016\/S0021-9258(17)31468-0","article-title":"Oxidation of hemoglobin and the enhancement produced by nitroblue tetrazolium.","volume":"269","author":"Abugo","year":"1994","journal-title":"J. Biol. Chem."},{"key":"B2","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1016\/j.lfs.2015.05.010","article-title":"Amino acids of importance for the antioxidant activity of human serum albumin as revealed by recombinant mutants and genetic variants.","volume":"134","author":"Anraku","year":"2015","journal-title":"Life Sci."},{"key":"B3","doi-asserted-by":"publisher","first-page":"3968","DOI":"10.1002\/jps.22571","article-title":"Quantitative analysis of cysteine-34 on the anitioxidative properties of human serum albumin in hemodialysis patients.","volume":"100","author":"Anraku","year":"2011","journal-title":"J. Pharm. Sci."},{"key":"B4","doi-asserted-by":"publisher","first-page":"5000","DOI":"10.1073\/pnas.82.15.5000","article-title":"Protein states and proteinquakes.","volume":"82","author":"Ansari","year":"1985","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B5","doi-asserted-by":"publisher","first-page":"1537","DOI":"10.1073\/pnas.0409518102","article-title":"The position of Hippopotamidae within Cetartiodactyla.","volume":"102","author":"Boisserie","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B6","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1080\/10715760400024935","article-title":"Differential effects of cysteine and methionine residues in the antioxidant activity of human serum albumin.","volume":"39","author":"Bourdon","year":"2005","journal-title":"Free Radic. Res."},{"key":"B7","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/s0169-5347(97)01054-9","article-title":"The behavioural and physiological ecology of diving.","volume":"12","author":"Boyd","year":"1997","journal-title":"Trends Ecol. Evol."},{"key":"B8","first-page":"65","author":"Brandts","year":"1969","journal-title":"Structure and Stability of Biological Macromolecules."},{"key":"B9","doi-asserted-by":"publisher","first-page":"5473","DOI":"10.1016\/j.bbagen.2013.04.017","article-title":"Oxidized albumin. The long way of a protein of uncertain function.","volume":"1830","author":"Bruschi","year":"2013","journal-title":"Biochim. Biophys. Acta Gen. Subj."},{"key":"B10","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1016\/j.cbpa.2010.11.029","article-title":"Differential antioxidant protection in tissues from marine mammals with distinct diving capacities. Shallow\/short vs. deep\/long divers.","volume":"158","author":"Cant\u00fa-Medell\u00edn","year":"2011","journal-title":"Comp. Biochem. Physiol. A Mol. Integr. Physiol."},{"key":"B11","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0021-9258(19)81445-X","article-title":"Removal of fatty acids from serum albumin by charcoal treatment.","volume":"242","author":"Chen","year":"1967","journal-title":"J. Biol. Chem."},{"key":"B12","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1038\/nature13909","article-title":"Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.","volume":"515","author":"Chouchani","year":"2014","journal-title":"Nature"},{"key":"B13","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1002\/bies.950080204","article-title":"Disulphide bonds and protein stability.","volume":"8","author":"Creighton","year":"1988","journal-title":"BioEssays"},{"key":"B14","doi-asserted-by":"crossref","DOI":"10.1201\/9781420041637","author":"Dierauf","year":"2001","journal-title":"CRC Handbook of Marine Mammal Medicine: Health, Disease, and Rehabilitation."},{"key":"B15","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1016\/s1095-6433(98)00012-9","article-title":"Diving seals, ischemia-reperfusion and oxygen radicals.","volume":"119","author":"Elsner","year":"1998","journal-title":"Comp. Biochem. Physiol. A Mol. Integr. Physiol."},{"key":"B16","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1578\/am.32.2.2006.182","article-title":"Hematology, serum chemistry, and cytology findings from apparently healthy Atlantic bottlenose dolphins (Tursiops truncatus) inhabiting the estuarine waters of Charleston, South Carolina.","volume":"32","author":"Fair","year":"2006","journal-title":"Aquat. Mamm."},{"key":"B17","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.mam.2011.12.002","article-title":"Human serum albumin: from bench to bedside.","volume":"33","author":"Fanali","year":"2012","journal-title":"Mol. Asp Med."},{"key":"B18","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1080\/15216540500404093","article-title":"The extraordinary ligand binding properties of human serum albumin.","volume":"57","author":"Fasano","year":"2005","journal-title":"IUBMB Life"},{"key":"B19","doi-asserted-by":"publisher","first-page":"5555","DOI":"10.1073\/pnas.96.10.5555","article-title":"The developing renal, reproductive, and respiratory systems of the African elephant suggest an aquatic ancestry.","volume":"96","author":"Gaeth","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B20","doi-asserted-by":"publisher","first-page":"738","DOI":"10.1111\/mms.12391","article-title":"Circulating glutathione concentrations in marine, semiaquatic, and terrestrial mammals.","volume":"33","author":"Garc\u00eda-Casta\u00f1eda","year":"2017","journal-title":"Mar. Mamm. Sci."},{"key":"B21","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/j.cbpa.2007.04.017","article-title":"Annual, seasonal and individual variation in hematology and clinical blood chemistry profiles in bottlenose dolphins (Tursiops truncatus) from Sarasota Bay, Florida.","volume":"148","author":"Hall","year":"2007","journal-title":"Comp. Biochem. Physiol. A Mol. Integr. Physiol."},{"key":"B22","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/s0022-5193(03)00073-0","article-title":"Optimal diving under the risk of predation.","volume":"223","author":"Heithaus","year":"2003","journal-title":"J. Theor. Biol."},{"key":"B23","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1016\/j.jep.2010.11.005","article-title":"Antioxidant and anti-inflammatory properties of Cardiospermum halicacabum and its reference compounds ex vivo and in vivo.","volume":"133","author":"Huang","year":"2011","journal-title":"J. Ethnopharm."},{"key":"B24","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1016\/j.freeradbiomed.2005.03.008","article-title":"Hypoxia-inducible factor 1 proteomics and diving adaptations in ringed seal.","volume":"39","author":"Johnson","year":"2005","journal-title":"Free Radic. Biol. Med."},{"key":"B25","doi-asserted-by":"publisher","first-page":"349","DOI":"10.2174\/1389203003381315","article-title":"The use of circular dichroism in the investigation of protein structure and function.","volume":"1","author":"Kelly","year":"2000","journal-title":"Curr. Protein Pept. Sci."},{"key":"B26","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1016\/j.profoo.2015.01.030","article-title":"In vivo study on albumin and total protein in white rat (Rattus Norvegicus) after feeding of enteral formula from tempe and local food.","volume":"3","author":"Khasanah","year":"2015","journal-title":"Proc. Food Sci."},{"key":"B27","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1146\/annurev.physiol.60.1.19","article-title":"The physiological basis of diving to depth: birds and mammals.","volume":"60","author":"Kooyman","year":"1998","journal-title":"Annu. Rev. Physiol."},{"key":"B28","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/0022-2836(82)90515-0","article-title":"A simple method for displaying the hydropathic character of a protein.","volume":"157","author":"Kyte","year":"1982","journal-title":"J. Mol. Biol."},{"key":"B29","doi-asserted-by":"publisher","first-page":"5786","DOI":"10.1073\/pnas.0800884105","article-title":"Stable isotope evidence for an amphibious phase in early proboscidean evolution.","volume":"105","author":"Liu","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B30","doi-asserted-by":"publisher","first-page":"1823","DOI":"10.1093\/molbev\/msi179","article-title":"A retroposon analysis of Afrotherian phylogeny.","volume":"22","author":"Nishihara","year":"2005","journal-title":"Mol. Biol. Evol."},{"key":"B31","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/j.jmb.2011.02.053","article-title":"Contribution of hydrophobic interactions to protein stability.","volume":"408","author":"Pace","year":"2011","journal-title":"J. Mol. Biol."},{"journal-title":"All about Albumin: Biochemistry, Genetics, and Medical Applications.","year":"1995","author":"Peters","key":"B32"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1098\/rsos.171058","article-title":"Identification of allosteric disulfides from labile bonds in X-ray structures.","volume":"5","author":"Pijning","year":"2018","journal-title":"Roy. Soc. Open Sci."},{"key":"B34","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.ejmech.2015.04.040","article-title":"The role of antioxidants in the chemistry of oxidative stress: a review.","volume":"97","author":"Pisoschi","year":"2015","journal-title":"Eur. J. Med. Chem."},{"key":"B35","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1002\/cphy.c091003","article-title":"Diving mammals.","volume":"1","author":"Ponganis","year":"2011","journal-title":"Compr. Physiol."},{"key":"B36","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.cbpa.2014.02.017","article-title":"Relating diving behavior and antioxidant status: insights from oxidative stress biomarkers in the blood of two distinct divers, Mirounga leonina and Arctocephalus australis.","volume":"173","author":"Righetti","year":"2014","journal-title":"Comp. Biochem. Physiol. A Mol. Integr. Physiol."},{"key":"B37","doi-asserted-by":"publisher","first-page":"1783","DOI":"10.1016\/j.febslet.2008.04.057","article-title":"The antioxidant properties of serum albumin.","volume":"582","author":"Roche","year":"2008","journal-title":"FEBS Lett."},{"key":"B38","doi-asserted-by":"publisher","first-page":"890","DOI":"10.1016\/0006-291x(90)90759-g","article-title":"The triterpene celastrol as a very potent inhibitor of lipid peroxidation in mitochondria.","volume":"172","author":"Sassa","year":"1990","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"B39","doi-asserted-by":"crossref","first-page":"3091","DOI":"10.1242\/jeb.200.24.3091","article-title":"Diving and swimming performance of white whales, Delphinapterus leucas: an assessment of plasma lactate and blood gas levels and respiratory rates.","volume":"200","author":"Shaffer","year":"1997","journal-title":"J. Exp. Biol."},{"key":"B40","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1098\/rsbl.2006.0566","article-title":"Eat now, pay later? Evidence of deferred food-processing costs in diving seals.","volume":"3","author":"Sparling","year":"2007","journal-title":"Biol. Lett."},{"key":"B41","doi-asserted-by":"publisher","first-page":"3389","DOI":"10.1093\/nar\/25.17.3389","article-title":"Gapped BLAST and PSI-BLAST: a new generation of protein database search programs.","volume":"25","author":"Stephen","year":"1997","journal-title":"Nucleic Acids Res."},{"key":"B42","doi-asserted-by":"crossref","first-page":"6846","DOI":"10.1016\/S0021-9258(17)39927-1","article-title":"Rat liver pre-proalbumin: complete amino acid sequence of the pre-piece. Analysis of the direct translation product of albumin messenger RNA.","volume":"252","author":"Strauss","year":"1977","journal-title":"J. Biol. Chem."},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1186\/2110-5820-3-4","article-title":"Specific antioxidant properties of human serum albumin.","volume":"3","author":"Taverna","year":"2013","journal-title":"Ann. Intensive Care"},{"key":"B44","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1111\/j.1469-7998.1991.tb04801.x","article-title":"Movements, diving and foraging behaviour of grey seals (Halichoerus grypus).","volume":"224","author":"Thompson","year":"1991","journal-title":"J. Zool."},{"key":"B45","doi-asserted-by":"publisher","first-page":"1690","DOI":"10.1016\/j.carres.2009.05.006","article-title":"Antioxidant properties of some different molecular weight chitosans.","volume":"344","author":"Tomida","year":"2009","journal-title":"Carbohydr. Res."},{"key":"B46","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/j.jembe.2007.02.003","article-title":"Glutathione protection against dive-associated ischemia\/reperfusion in ringed seal tissues.","volume":"345","author":"V\u00e1zquez-Medina","year":"2007","journal-title":"J. Exp. Mar. Biol. Ecol."},{"key":"B47","doi-asserted-by":"publisher","first-page":"885","DOI":"10.1016\/s1095-6433(02)00253-2","article-title":"Comparison between the antioxidant status of terrestrial and diving mammals.","volume":"133","author":"Wilhelm Filho","year":"2002","journal-title":"Comp. Biochem. Physiol. A Mol. Integr. Physiol."},{"key":"B48","doi-asserted-by":"crossref","first-page":"2739","DOI":"10.1242\/jeb.202.20.2739","article-title":"The diving physiology of bottlenose dolphins (Tursiops truncatus). I. Balancing the demands of exercise for energy conservation at depth.","volume":"202","author":"Williams","year":"1999","journal-title":"J. Exp. Biol."},{"key":"B49","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1002\/9781444345988.ch13","article-title":"Ischemia\/reperfusion in diving birds and mammals: how they avoid oxidative damage","author":"Zenteno-Savin","year":"2012","journal-title":"Oxidative Stress in Aquatic Ecosystems"}],"container-title":["Frontiers in Physiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fphys.2020.598451\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,26]],"date-time":"2022-11-26T03:41:26Z","timestamp":1669434086000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fphys.2020.598451\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,2]]},"references-count":49,"alternative-id":["10.3389\/fphys.2020.598451"],"URL":"https:\/\/doi.org\/10.3389\/fphys.2020.598451","relation":{},"ISSN":["1664-042X"],"issn-type":[{"type":"electronic","value":"1664-042X"}],"subject":[],"published":{"date-parts":[[2020,11,2]]},"article-number":"598451"}}