{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T03:14:42Z","timestamp":1779333282678,"version":"3.51.4"},"reference-count":61,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,10,10]],"date-time":"2022-10-10T00:00:00Z","timestamp":1665360000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005916","name":"Universidad de La Frontera","doi-asserted-by":"publisher","award":["Chile Project DI21-0030."],"award-info":[{"award-number":["Chile Project DI21-0030."]}],"id":[{"id":"10.13039\/501100005916","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Physiol."],"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> Postexercise hypotension (PEH) is a common physiological phenomenon occurring immediately after endurance training (ET), resistance training (RT), and ET plus RT, also termed concurrent training (CT); however, there is little knowledge about the interindividual and magnitude response of PEH in morbidly obese patients.<\/jats:p><jats:p><jats:bold>Aim:<\/jats:bold> The aims of this study were (1) to investigate the effect of CT order (ET + RT vs. RT + ET) on the blood pressure responses; 2) characterize these responses in responders and nonresponders, and 3) identify potential baseline outcomes for predicting blood pressure decreases as responders.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> A quasi-experimental study developed in sedentary morbidly obese men and women (age 43.6 \u00b1 11.3\u00a0years; body mass index [BMI] \u226540\u00a0kg\/m<jats:sup>2<\/jats:sup>) was assigned to a CT group of ET plus RT (ET + RT; <jats:italic>n<\/jats:italic> = 19; BMI 47.8 \u00b1 16.7) or RT plus ET order group (RT + ET; <jats:italic>n<\/jats:italic> = 17; BMI 43.0 \u00b1 8.0). Subjects of both groups received eight exercise sessions over four weeks. Primary outcomes include systolic (SBP), diastolic (DBP), mean arterial pressure [MAP], heart rate at rest [HR], and pulse pressure [PP] measurements before and after 10\u00a0min post-exercise. Secondary outcomes were other anthropometric, body composition, metabolic, and physical fitness parameters. Using the delta \u2206SBP reduction, quartile categorization (Q) in \u201chigh\u201d (Rs: quartile 4), \u201cmoderate\u201d (MRs: quartile 3), \u201clow\u201d (LRs: quartile 2), and \u201cnonresponders\u201d (NRs: quartile 1) was reported.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Significant pre\u2013post changes were observed in ET + RT in session 2 for SBP (131.6 vs. 123.4\u00a0mmHg, <jats:italic>p<\/jats:italic> = 0.050) and session 4 (131.1 vs. 125.2\u00a0mmHg, <jats:italic>p<\/jats:italic> = 0.0002), while the RT + ET group showed significant reductions in session 4 (134.2 vs. 125.3\u00a0mmHg, <jats:italic>p<\/jats:italic> &amp;lt; 0.001). No significant differences were detected in the sum of the eight sessions for SBP (\u2211\u2206SBP) between ET + RT vs. RT + ET (\u22125.7 vs. \u22124.3\u00a0mmHg, <jats:italic>p<\/jats:italic> = 0.552). Interindividual analyses revealed significant differences among frequencies comparing Q1 \u201cNRs\u201d (<jats:italic>n<\/jats:italic> = 8; 22.2%), Q2 \u201cLRs\u201d (<jats:italic>n<\/jats:italic> = 8; 22.2%), Q3 \u201cMRs\u201d (<jats:italic>n<\/jats:italic> = 9; 25.0%), and Q4 \u201cHRs\u201d (<jats:italic>n<\/jats:italic> = 11; 30.5%), <jats:italic>p<\/jats:italic> &amp;lt; 0.0001. Quartile comparisons showed significant differences in SBP changes (<jats:italic>p<\/jats:italic> = 0.035). Linear regression analyses revealed significant association between \u2211\u2206SBP with body fat % (\u03b2 \u20133.826, <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup> 0.211 [21.1%], <jats:italic>p<\/jats:italic> = 0.031), skeletal muscle mass [\u03b2 \u20132.150, <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup> 0.125 (12.5%), <jats:italic>p<\/jats:italic> = 0.023], fasting glucose [\u03b2 1.273, <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup> 0.078 (7.8%), <jats:italic>p<\/jats:italic> = 0.003], triglycerides [\u03b2 0.210, <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup> 0.014 (1.4%), <jats:italic>p<\/jats:italic> = 0.008], and the 6-min walking test [\u03b2 0.183, <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup> 0.038 (3.8%), <jats:italic>p<\/jats:italic> = 0.044].<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> The CT order of ET + RT and RT + ET promote a similar \u2018magnitude\u2019 in the postexercise hypotensive effects during the eight sessions of both CT orders in 4 weeks of training duration, revealing \u201cnonresponders\u201d and \u2018high\u2019 responders that can be predicted from body composition, metabolic, and physical fitness outcomes.<\/jats:p>","DOI":"10.3389\/fphys.2022.913645","type":"journal-article","created":{"date-parts":[[2022,10,10]],"date-time":"2022-10-10T08:14:17Z","timestamp":1665389657000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":5,"title":["Characterizing the interindividual postexercise hypotension response for two order groups of concurrent training in patients with morbid obesity"],"prefix":"10.3389","volume":"13","author":[{"given":"Cristian","family":"\u00c1lvarez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"Guede-Rojas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo","family":"Ram\u00edrez-Campillo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David C.","family":"Andrade","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaime","family":"V\u00e1squez-G\u00f3mez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Rodr\u00edguez-Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuel Gomes","family":"Ciolac","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felipe","family":"Caama\u00f1o-Navarrete","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Delgado-Floody","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2022,10,10]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1363","DOI":"10.4067\/S0034-98872013001100001","article-title":"Efectos de una sesi\u00f3n de ejercicio aer\u00f3bico en la presi\u00f3n arterial de ni\u00f1os, adolescentes y adultos sanos","volume":"141","author":"\u00c1lvarez","year":"2013","journal-title":"Revista Medica de Chile"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1443","DOI":"10.3389\/fphys.2018.01443","article-title":"Prevalence of non-responders for blood pressure and cardiometabolic risk factors among prehypertensive women after long-term high-intensity interval training","volume":"9","author":"\u00c1lvarez","year":"2018","journal-title":"Front. 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