{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T09:41:12Z","timestamp":1790674872866,"version":"4.1.0"},"reference-count":40,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,3,10]],"date-time":"2023-03-10T00:00:00Z","timestamp":1678406400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Physiol."],"abstract":"<jats:p><jats:bold>Purpose:<\/jats:bold> This study aimed to investigate muscle damage when performing equal mechanical work of fast and slow pedaling speed by eccentric muscle actions (ECCs) cycling.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> Nineteen young men [mean \u00b1 standard deviation (SD) age: 21.0 \u00b1 2.2\u00a0years; height: 172.7 \u00b1 5.9\u00a0cm; and body mass: 70.2 \u00b1 10.5\u00a0kg] performed maximal effort of ECCs cycling exercise with fast speed (Fast) and slow speed trials (Slow). First, subjects performed the Fast for 5\u00a0min by one leg. Second, Slow performed until the total mechanical work was equal to that generated during Fast other one leg. Changes in maximal voluntary isometric contraction (MVC) torque of knee extension, isokinetic pedaling peak torque (IPT), range of motion (ROM), muscle soreness, thigh circumference, muscle echo intensity, and muscle stiffness were assessed before exercise, and immediately after exercise, and 1 and 4\u00a0days after exercise.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Exercise time was observed in the Slow (1422.0 \u00b1 330.0\u00a0s) longer than Fast (300.0 \u00b1 0.0\u00a0s). However, a significant difference was not observed in total work (Fast:214.8 \u00b1 42.4\u00a0J\/kg, Slow: 214.3 \u00b1 42.2\u00a0J\/kg). A significant interaction effect was not observed in peak values of MVC torque (Fast:1.7 \u00b1 0.4 Nm\/kg, Slow: 1.8 \u00b1 0.5\u00a0Nm\/kg), IPT, muscle soreness (Fast:4.3 \u00b1 1.6\u00a0cm, Slow: 4.7 \u00b1 2.9\u00a0cm). In addition, ROM, circumference, muscle thickness, muscle echo intensity, and muscle stiffness also showed no significant interaction.<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> The magnitude of muscle damage is similar for ECCs cycling with equal work regardless of velocity.<\/jats:p>","DOI":"10.3389\/fphys.2023.1140359","type":"journal-article","created":{"date-parts":[[2023,3,10]],"date-time":"2023-03-10T05:22:35Z","timestamp":1678425755000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":5,"title":["Pedal cadence does not affect muscle damage to eccentric cycling performed at similar mechanical work"],"prefix":"10.3389","volume":"14","author":[{"given":"Hisashi","family":"Ueda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riki","family":"Saegusa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yosuke","family":"Tsuchiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eisuke","family":"Ochi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2023,3,10]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1007\/s00421-020-04548-6","article-title":"Moving forward with backward pedaling: A review on eccentric cycling","volume":"121","author":"Barreto","year":"2021","journal-title":"Eur. 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