{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T05:58:07Z","timestamp":1773208687152,"version":"3.50.1"},"reference-count":17,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T00:00:00Z","timestamp":1692835200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Physiol."],"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> Prone position ventilation (PPV) can significantly improve oxygenation index and blood oxygen saturation in most (70%\u201380%) patients with acute respiratory distress syndrome. However, although PPV is not an invasive procedure, there are many potential PPV-related complications, such as nerve compression, crush injury, venous stasis (e.g., facial oedema), pressure sores, retinal damage, vomiting, and arrhythmia, with an incidence of up to 56.9%. Nursing managers have focused on reducing the occurrence of PPV-related complications and improving safety.<\/jats:p><jats:p><jats:bold>Objective:<\/jats:bold> To construct a prone ventilation management scheme for patients with severe coronavirus disease 2019 (COVID\u201319) and analyse its application effect.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> Based on a previous evidence-based study combined with the COVID-19 Diagnosis and Treatment Protocol (Trial Edition 9), a prone ventilation management protocol for severe COVID-19 was formulated and applied to COVID-19 patients in the intensive care unit of a designated hospital. A prospective self-control study was used to compare changes in the oxygenation index and other outcome indicators before and after the intervention.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> The oxygenation index of patients after intervention (321.22 \u00b1 19.77\u00a0mmHg) was significantly higher (<jats:italic>p<\/jats:italic> &amp;lt; 0.05) than before intervention (151.59 \u00b1 35.49\u00a0mmHg). The difference in oxygenation index in different prone position ventilation durations was statistically significant (<jats:italic>p<\/jats:italic> &amp;lt; 0.05). Nursing quality evaluation indicators showed that the implementation rate of gastric residual volume assessment was 100% and the incidence of occupational exposure and cross-infection was 0%; the incidences of pressure ulcers, drug extravasation, and facial oedema were 13.64% (3\/22), 4.54% (1\/22), and 4.54% (1\/22), respectively. The incidence of unplanned extubation, aspiration, and falls\/falls was 0%.<\/jats:p>","DOI":"10.3389\/fphys.2023.1152723","type":"journal-article","created":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T09:14:00Z","timestamp":1692868440000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Construction and application of prone position ventilation management scheme for severe COVID-19 patients"],"prefix":"10.3389","volume":"14","author":[{"given":"Xiuwen","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cao","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yao","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiqing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2023,8,24]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1468","DOI":"10.1038\/s41591-022-01855-7","article-title":"Modeling transmission of SARS-CoV-2 omicron in China","volume":"28","author":"Cai","year":"2022","journal-title":"Nat. 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