{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T13:32:59Z","timestamp":1793799179059,"version":"4.6.1"},"reference-count":81,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,7,19]],"date-time":"2024-07-19T00:00:00Z","timestamp":1721347200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Physiol."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The Fibromyalgia Syndrome (FMS) is a multifaceted chronic pain disorder that exerts a substantial impact on the overall state of health and quality of life of patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>Investigate the effects of exercise therapy and adherence to the American College of Sports Medicine (ACSM) guidelines on treatment outcomes in FMS patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The literature search, which concluded in October 2023, encompassed studies investigating the impact of exercise interventions on patients diagnosed with FMS and providing adequate data for calculating standardized mean difference (SMD). The primary outcome measures encompassed the Fibromyalgia Impact Questionnaire (FIQ) and Health Assessment Questionnaire (HAQ), while secondary outcome measures comprised pain levels, sleep quality, fatigue, and mental health.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 4,008 records, 19 studies (patients = 857) were eligible for qualitative synthesis. The meta-analysis revealed that the SMD for overall state of health impact was \u22120.94 (95%CI \u22121.26, \u22120.63), and the pooled SMD for the subgroup with high adherence to ACSM guidelines was \u22121.17 (95%CI \u22121.65, \u22120.69). The SMD for the subgroup with low or uncertain adherence was \u22120.73 (95%CI \u22121.12, \u22120.34). The overall effects included a \u22121.21 (95%CI \u22121.62, \u22120.79) SMD for pain relief, with high adherence achieving a \u22121.32 (95%CI \u22122.00, \u22120.64) SMD and low adherence a \u22121.06 (95%CI \u22121.55, \u22120.57) SMD. Mental health improvements showed a \u22120.95 (95%CI \u22121.32, \u22120.57) overall SMD, with high and low adherence subgroups at \u22120.96 (95%CI \u22121.62, \u22120.30) and \u22120.94 (95%CI \u22121.29, \u22120.60), respectively. Sleep quality impact was \u22121.59 (95%CI \u22122.31, \u22120.87) overall, with high adherence at \u22121.71 (95%CI \u22122.58, \u22120.83) and low adherence at \u22121.11 (95%CI \u22121.88, \u22120.33). Fatigue impact had a \u22121.55 (95%CI \u22122.26, \u22120.85) overall SMD, with \u22121.77 (95%CI \u22123.18, \u22120.36) for high adherence and \u22121.35 (95%CI \u22122.03, \u22120.66) for low adherence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Exercise therapy can improve the overall state of health, pain, sleep, and fatigue of FMS patients, particularly when adhering to ACSM guidelines. However, adherence levels do not affect mental health gains, indicating a need for future research on psychological impact.<\/jats:p><\/jats:sec><jats:sec><jats:title>Systematic Review Registration:<\/jats:title><jats:p><jats:ext-link>https:\/\/inplasy.com\/inplasy-2024-3-0106\/<\/jats:ext-link>, identifier INPLASY202430106.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fphys.2024.1413038","type":"journal-article","created":{"date-parts":[[2024,7,19]],"date-time":"2024-07-19T04:34:17Z","timestamp":1721363657000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":27,"title":["Adherence to ACSM exercise guidelines and its influence on Fibromyalgia treatment outcomes: a meta-analysis of randomized controlled trials"],"prefix":"10.3389","volume":"15","author":[{"given":"Tianran","family":"Han","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Xi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jialin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiqian","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linhua","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,7,19]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"315","DOI":"10.15537\/smj.42.3.20200768","article-title":"Effects of chronic pain on sleep quality and depression: a cross-sectional study","volume":"42","author":"Alhalal","year":"2021","journal-title":"Saudi Med. J."},{"key":"B2","doi-asserted-by":"publisher","first-page":"e32489","DOI":"10.7759\/cureus.32489","article-title":"Prevalence of fibromyalgia syndrome in taif city, Saudi Arabia","volume":"14","author":"Althobaiti","year":"2022","journal-title":"Cureus"},{"key":"B3","doi-asserted-by":"publisher","first-page":"828","DOI":"10.23736\/s0022-4707.18.08897-7","article-title":"Therapeutic validity of exercise interventions in the management of fibromyalgia","volume":"59","author":"\u00c1lvarez-Gallardo","year":"2019","journal-title":"J. Sports Med. Phys. Fit."},{"key":"B4","doi-asserted-by":"publisher","first-page":"663","DOI":"10.23736\/s1973-9087.17.04876-6","article-title":"Muscle stretching exercises and resistance training in fibromyalgia: which is better? A three-arm randomized controlled trial","volume":"54","author":"Assump\u00e7\u00e3o","year":"2018","journal-title":"Eur. J. Phys. Rehabil. Med."},{"key":"B5","doi-asserted-by":"publisher","first-page":"1865","DOI":"10.1016\/j.apmr.2020.05.022","article-title":"Effectiveness of high-intensity interval training vs moderate-intensity continuous training in patients with fibromyalgia: a pilot randomized controlled trial","volume":"101","author":"Atan","year":"2020","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"B6","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1016\/j.jbspin.2008.06.002","article-title":"Fibromyalgia syndrome in the general population of France: a prevalence study","volume":"76","author":"Bannwarth","year":"2009","journal-title":"Jt. Bone Spine"},{"key":"B7","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1002\/da.22986","article-title":"Joint and dose-dependent associations between aerobic and muscle-strengthening activity with depression: a cross-sectional study of 1.48 million adults between 2011 and 2017","volume":"37","author":"Bennie","year":"2020","journal-title":"Depress Anxiety"},{"key":"B8","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1016\/j.semarthrit.2008.12.003","article-title":"Prevalence of fibromyalgia: a survey in five European countries","volume":"39","author":"Branco","year":"2010","journal-title":"Semin. Arthritis Rheum."},{"key":"B9","doi-asserted-by":"publisher","first-page":"Cd003786","DOI":"10.1002\/14651858.CD003786.pub2","article-title":"Exercise for treating fibromyalgia syndrome","author":"Busch","year":"2007","journal-title":"Cochrane Database Syst. Rev."},{"key":"B10","doi-asserted-by":"publisher","first-page":"1130","DOI":"10.1002\/14651858.CD003786.pub2","article-title":"Exercise for fibromyalgia: a systematic review","volume":"35","author":"Busch","year":"2008","journal-title":"J. Rheumatol."},{"key":"B11","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1007\/s11916-011-0214-2","article-title":"Exercise therapy for fibromyalgia","volume":"15","author":"Busch","year":"2011","journal-title":"Curr. Pain Headache Rep."},{"key":"B12","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1007\/s11916-016-0556-x","article-title":"Fibromyalgia pathogenesis and treatment options update","volume":"20","author":"Chinn","year":"2016","journal-title":"Curr. Pain Headache Rep."},{"key":"B13","doi-asserted-by":"publisher","first-page":"1181327","DOI":"10.3389\/fphys.2023.1181327","article-title":"Effects of exercise based on ACSM recommendations on bone mineral density in individuals with osteoporosis: a systematic review and meta-analyses of randomized controlled trials","volume":"14","author":"Cui","year":"2023","journal-title":"Front. Physiol."},{"key":"B14","doi-asserted-by":"publisher","first-page":"67","DOI":"10.55133\/eji.310108","article-title":"Significance of inflammatory markers in primary Fibromyalgia syndrome and their relation in assessing the disease severity","volume":"31","author":"El-Sawy","year":"2024","journal-title":"Egypt J. Immunol."},{"key":"B15","doi-asserted-by":"publisher","first-page":"752","DOI":"10.1016\/j.apmr.2020.06.019","article-title":"Effectiveness of exercise on fatigue and sleep quality in fibromyalgia: a systematic review and meta-analysis of randomized trials","volume":"102","author":"Est\u00e9vez-L\u00f3pez","year":"2021","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"B16","doi-asserted-by":"publisher","first-page":"2261","DOI":"10.3390\/ijerph20032261","article-title":"Can an aerobic exercise programme improve the response of the growth hormone in fibromyalgia patients? A randomised controlled trial","volume":"20","author":"Estrada-Marc\u00e9n","year":"2023","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"B17","doi-asserted-by":"publisher","first-page":"3765","DOI":"10.3390\/jcm10173765","article-title":"Effects of physiotherapy vs. Acupuncture in quality of life, pain, stiffness, difficulty to work and depression of women with fibromyalgia: a randomized controlled trial","volume":"10","author":"Garrido-Ardila","year":"2021","journal-title":"J. Clin. Med."},{"key":"B18","doi-asserted-by":"publisher","first-page":"e90767","DOI":"10.1371\/journal.pone.0090767","article-title":"Strengthening exercises improve symptoms and quality of life but do not change autonomic modulation in fibromyalgia: a randomized clinical trial","volume":"9","author":"Gavi","year":"2014","journal-title":"PLoS One"},{"key":"B19","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1002\/art.20063","article-title":"Evidence of augmented central pain processing in idiopathic chronic low back pain","volume":"50","author":"Giesecke","year":"2004","journal-title":"Arthritis Rheum."},{"key":"B20","doi-asserted-by":"publisher","first-page":"1205","DOI":"10.55563\/clinexprheumatol\/257e99","article-title":"Fibromyalgia: one year in review 2023","volume":"41","author":"Giorgi","year":"2023","journal-title":"Clin. Exp. Rheumatol."},{"key":"B21","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.70252\/LAZD6794","article-title":"Resistance exercise training on disease impact, pain catastrophizing and autonomic modulation in women with fibromyalgia","volume":"10","author":"Glasgow","year":"2017","journal-title":"Int. J. Exerc Sci."},{"key":"B22","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/j.biopsycho.2016.09.007","article-title":"Controllability and hippocampal activation during pain expectation in fibromyalgia syndrome","volume":"121","author":"Gonz\u00e1lez-Rold\u00e1n","year":"2016","journal-title":"Biol. Psychol."},{"key":"B23","doi-asserted-by":"publisher","first-page":"1285","DOI":"10.1016\/j.spinee.2017.04.025","article-title":"Lumbar muscle structure and function in chronic versus recurrent low back pain: a cross-sectional study","volume":"17","author":"Goubert","year":"2017","journal-title":"Spine J."},{"key":"B24","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1038\/s41386-019-0439-z","article-title":"Sleep deficiency and chronic pain: potential underlying mechanisms and clinical implications","volume":"45","author":"Haack","year":"2020","journal-title":"Neuropsychopharmacology"},{"key":"B25","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1136\/ard.60.1.21","article-title":"Strength training induced adaptations in neuromuscular function of premenopausal women with fibromyalgia: comparison with healthy women","volume":"60","author":"H\u00e4kkinen","year":"2001","journal-title":"Ann. Rheum. Dis."},{"key":"B26","doi-asserted-by":"publisher","first-page":"2075","DOI":"10.3390\/ijerph18042075","article-title":"Immediate effects of a telerehabilitation program based on aerobic exercise in women with fibromyalgia","volume":"18","author":"Hernando-Garijo","year":"2021","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"B27","doi-asserted-by":"publisher","first-page":"3634","DOI":"10.3390\/ijerph17103634","article-title":"Low-intensity physical exercise improves pain catastrophizing and other psychological and physical aspects in women with fibromyalgia: a randomized controlled trial","volume":"17","author":"Izquierdo-Alventosa","year":"2020","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"B28","doi-asserted-by":"publisher","first-page":"293","DOI":"10.3969\/j.issn.1004-583X.200019.04.00","article-title":"Progress in diagnosis and treatment of fibromyalgia syndrome","volume":"34","author":"Juan","year":"2019","journal-title":"Clin. Focus"},{"key":"B29","doi-asserted-by":"publisher","first-page":"1029","DOI":"10.1080\/13548506.2020.1724308","article-title":"Chronic neck pain and depression: the mediating role of sleep quality and exercise","volume":"25","author":"Juan","year":"2020","journal-title":"Psychol. Health Med."},{"key":"B30","doi-asserted-by":"publisher","first-page":"1713","DOI":"10.1016\/j.apmr.2005.04.014","article-title":"The effects of a 12-week strength-training program on strength and functionality in women with fibromyalgia","volume":"86","author":"Kingsley","year":"2005","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"B31","doi-asserted-by":"publisher","first-page":"1","DOI":"10.12740\/PP\/OnlineFirst\/176000","article-title":"Psychopathological symptoms in fibromyalgia and their associations with resistance to pharmacotherapy with SNRI","author":"Krupa","year":"2024","journal-title":"Psychiatr. Pol."},{"key":"B32","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1186\/s13075-015-0679-1","article-title":"Resistance exercise improves muscle strength, health status and pain intensity in fibromyalgia--a randomized controlled trial","volume":"17","author":"Larsson","year":"2015","journal-title":"Arthritis Res. Ther."},{"key":"B33","doi-asserted-by":"publisher","first-page":"75","DOI":"10.16306\/j.1008-861x.2024.01.011","article-title":"Analysis of current research status of traditional Chinese medicine in fibromyalgia syndrome based on CiteSpace","volume":"38","author":"Lee","year":"2024","journal-title":"Acad. J. Shanghai Univ. Traditional Chin. Med."},{"key":"B34","volume-title":"ACSM'S guidelines for exercise testing and prescription eleventh edition","author":"Liguori","year":"2021"},{"key":"B35","doi-asserted-by":"publisher","first-page":"4141","DOI":"10.1113\/jp273355","article-title":"Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena","volume":"595","author":"Lima","year":"2017","journal-title":"J. Physiol."},{"key":"B36","doi-asserted-by":"publisher","first-page":"1128","DOI":"10.3969\/j.issn.1003-6350.2020.09.012","article-title":"Depressive symptoms, sleep quality and cognitive characteristics of female patients with fibromyalgia","volume":"31","author":"Liu","year":"2020","journal-title":"Hainan Med. J."},{"key":"B37","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1136\/annrheumdis-2016-209724","article-title":"EULAR revised recommendations for the management of fibromyalgia","volume":"76","author":"Macfarlane","year":"2017","journal-title":"Ann. Rheum. Dis."},{"key":"B38","doi-asserted-by":"publisher","first-page":"7877","DOI":"10.3390\/ijms21217877","article-title":"Fibromyalgia: recent advances in diagnosis, classification, pharmacotherapy and alternative remedies","volume":"21","author":"Maffei","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"B39","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1186\/s12888-022-03762-0","article-title":"The interplay between multisite pain and insomnia on the risk of anxiety and depression: the HUNT study","volume":"22","author":"Marcuzzi","year":"2022","journal-title":"BMC Psychiatry"},{"key":"B40","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1186\/ar2146","article-title":"Biology and therapy of fibromyalgia. Stress, the stress response system, and fibromyalgia","volume":"9","author":"Martinez-Lavin","year":"2007","journal-title":"Arthritis Res. Ther."},{"key":"B41","doi-asserted-by":"publisher","first-page":"Cd010664","DOI":"10.1002\/14651858.CD010664.pub2","article-title":"Cognitive-behavioural treatment for subacute and chronic neck pain","volume":"2015","author":"Monticone","year":"2015","journal-title":"Cochrane Database Syst. Rev."},{"key":"B42","doi-asserted-by":"publisher","first-page":"1563","DOI":"10.1016\/j.joca.2017.06.004","article-title":"The importance of dose in land-based supervised exercise for people with hip osteoarthritis. A systematic review and meta-analysis","volume":"25","author":"Moseng","year":"2017","journal-title":"Osteoarthr. Cartil."},{"key":"B43","doi-asserted-by":"publisher","first-page":"981","DOI":"10.1080\/17461391.2019.1683610","article-title":"Zumba dancing and aerobic exercise can improve working memory, motor function, and depressive symptoms in female patients with Fibromyalgia","volume":"20","author":"Norouzi","year":"2020","journal-title":"Eur. J. Sport Sci."},{"key":"B44","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1097\/j.pain.0000000000002319","article-title":"Central pain modulatory mechanisms of attentional analgesia are preserved in fibromyalgia","volume":"163","author":"Oliva","year":"2022","journal-title":"Pain"},{"key":"B45","doi-asserted-by":"publisher","first-page":"7574589","DOI":"10.1155\/2016\/7574589","article-title":"A new rehabilitation tool in fibromyalgia: the effects of perceptive rehabilitation on pain and function in a clinical randomized controlled trial","volume":"2016","author":"Paolucci","year":"2016","journal-title":"Evid. Based Complement. Altern. Med."},{"key":"B46","doi-asserted-by":"publisher","first-page":"101","DOI":"10.3233\/bmr-140497","article-title":"MMPI-2 profiles and illness perception in fibromyalgia syndrome: the role of therapeutic exercise as adapted physical activity","volume":"28","author":"Paolucci","year":"2015","journal-title":"J. Back Musculoskelet. Rehabil."},{"key":"B47","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1007\/s11926-000-0051-5","article-title":"Sympathetic nervous system function in fibromyalgia","volume":"2","author":"Petzke","year":"2000","journal-title":"Curr. Rheumatol. Rep."},{"key":"B48","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1080\/16506073.2023.2236296","article-title":"The effectiveness of cognitive behavioural therapy in chronic neck pain: a systematic review with meta-analysis","volume":"52","author":"Ploutarchou","year":"2023","journal-title":"Cogn. Behav. Ther."},{"key":"B49","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1136\/bmj.325.7357.185","article-title":"Prescribed exercise in people with fibromyalgia parallel group randomised controlled trial","author":"Richards","year":"2003","journal-title":"Chin. Ed. BMJ"},{"key":"B50","doi-asserted-by":"publisher","first-page":"1170621","DOI":"10.3389\/fphys.2023.1170621","article-title":"Optimal dose and type of exercise to reduce pain, anxiety and increase quality of life in patients with fibromyalgia. A systematic review with meta-analysis","volume":"14","author":"Rodr\u00edguez-Almagro","year":"2023","journal-title":"Front. Physiol."},{"key":"B51","doi-asserted-by":"publisher","first-page":"3826","DOI":"10.3390\/jcm10173826","article-title":"Effects of non-pharmacological treatment on pain, flexibility, balance and quality of life in women with fibromyalgia: a randomised clinical trial","volume":"10","author":"Rodr\u00edguez-Mansilla","year":"2021","journal-title":"J. Clin. Med."},{"key":"B52","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1097\/PHM.0b013e31824faa03","article-title":"Effects of exercise training and detraining in patients with fibromyalgia syndrome: a 3-yr longitudinal study","volume":"91","author":"Sa\u00f1udo","year":"2012","journal-title":"Am. J. Phys. Med. Rehabil."},{"key":"B53","doi-asserted-by":"publisher","first-page":"1838","DOI":"10.1016\/j.apmr.2010.09.006","article-title":"Aerobic exercise versus combined exercise therapy in women with fibromyalgia syndrome: a randomized controlled trial","volume":"91","author":"Sa\u00f1udo","year":"2010","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"B54","doi-asserted-by":"publisher","first-page":"521","DOI":"10.2340\/16501977-0814","article-title":"Effects of a prolonged exercise program on key health outcomes in women with fibromyalgia: a randomized controlled trial","volume":"43","author":"Sa\u00f1udo","year":"2011","journal-title":"J. Rehabil. Med."},{"key":"B55","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1196\/annals.1351.009","article-title":"Increased neural sympathetic activation in fibromyalgia syndrome","volume":"1069","author":"Sarzi-Puttini","year":"2006","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"B56","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1038\/s41584-020-00506-w","article-title":"Fibromyalgia: an update on clinical characteristics, aetiopathogenesis and treatment","volume":"16","author":"Sarzi-Puttini","year":"2020","journal-title":"Nat. Rev. Rheumatol."},{"key":"B57","doi-asserted-by":"publisher","first-page":"e0281593","DOI":"10.1371\/journal.pone.0281593","article-title":"The possible onset of fibromyalgia following acute COVID-19 infection","volume":"18","author":"Savin","year":"2023","journal-title":"PLoS One"},{"key":"B58","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/09638288.2023.2255130","article-title":"The effect of myofascial release of the physiological chains on the pain and health status in patients with fibromyalgia, compared to passive muscle stretching and a control group: a randomized controlled clinical trial","author":"Schulze","year":"2023","journal-title":"Disabil. Rehabil."},{"key":"B59","doi-asserted-by":"publisher","first-page":"213","DOI":"10.3233\/ch-141858","article-title":"A study to compare the therapeutic efficacy of aerobic exercise and paroxetine in fibromyalgia syndrome","volume":"57","author":"Sencan","year":"2004","journal-title":"J. Back Musculoskelet. Rehabilitation"},{"key":"B60","doi-asserted-by":"publisher","first-page":"3891","DOI":"10.3390\/ijms22083891","article-title":"Fibromyalgia: pathogenesis, mechanisms, diagnosis and treatment options update","volume":"22","author":"Siracusa","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"B61","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/j.pain.2007.03.015","article-title":"Spatial summation of mechanically evoked muscle pain and painful aftersensations in normal subjects and fibromyalgia patients","volume":"130","author":"Staud","year":"2007","journal-title":"Pain"},{"key":"B62","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1007\/s40279-013-0090-5","article-title":"The effects of stress on physical activity and exercise","volume":"44","author":"Stults-Kolehmainen","year":"2014","journal-title":"Sports Med."},{"key":"B63","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1186\/s12891-022-05047-9","article-title":"Does aerobic exercise effect pain sensitisation in individuals with musculoskeletal pain? A systematic review","volume":"23","author":"Tan","year":"2022","journal-title":"BMC Musculoskelet. Disord."},{"key":"B64","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1249\/JSR.0b013e31829a68cf","article-title":"ACSM's new preparticipation health screening recommendations from ACSM's guidelines for exercise testing and prescription, ninth edition","volume":"12","author":"Thompson","year":"2013","journal-title":"Curr. Sports Med. Rep."},{"key":"B65","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1177\/1559827620912192","article-title":"Exercise is medicine","volume":"14","author":"Thompson","year":"2020","journal-title":"Am. J. Lifestyle Med."},{"key":"B66","doi-asserted-by":"publisher","first-page":"538","DOI":"10.1016\/j.rbr.2013.02.001","article-title":"Effects of physical exercise on serum levels of serotonin and its metabolite in fibromyalgia: a randomized pilot study","volume":"53","author":"Valim","year":"2013","journal-title":"Rev. Bras. Reumatol."},{"key":"B67","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1007\/s10067-012-2100-7","article-title":"Challenges in demonstrating the effectiveness of multidisciplinary treatment on quality of life, participation and health care utilisation in patients with fibromyalgia: a randomised controlled trial","volume":"32","author":"van Eijk-Hustings","year":"2013","journal-title":"Clin. Rheumatol."},{"key":"B68","doi-asserted-by":"publisher","first-page":"S86","DOI":"10.1002\/acr.20531","article-title":"Measures of fibromyalgia: fibromyalgia impact Questionnaire (FIQ), brief pain inventory (BPI), multidimensional fatigue inventory (MFI-20), medical outcomes study (MOS) sleep scale, and multiple ability self-report Questionnaire (MASQ)","volume":"63","author":"Williams","year":"2011","journal-title":"Arthritis Care Res. Hob."},{"key":"B69","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1002\/art.1780380104","article-title":"The prevalence and characteristics of fibromyalgia in the general population","volume":"38","author":"Wolfe","year":"1995","journal-title":"Arthritis Rheum."},{"key":"B70","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.jpain.2008.07.003","article-title":"Hippocampal metabolite abnormalities in fibromyalgia: correlation with clinical features","volume":"10","author":"Wood","year":"2009","journal-title":"J. Pain"},{"key":"B71","doi-asserted-by":"publisher","first-page":"658","DOI":"10.16038\/j.1000-6710.2023.08.005","article-title":"New progress in exercise prescription for chronic diseases: an update of ACSM Exercise Testing and Exercise Prescription (11th edition)","volume":"42","author":"Xijuan","year":"2023","journal-title":"Chin. J. Sports Med."},{"key":"B72","doi-asserted-by":"publisher","first-page":"697","DOI":"10.3969\/j.issn.1006-9852.2023.09.009","article-title":"Research progress on the mechanism of fibromyalgia","volume":"29","author":"Yamei","year":"2023","journal-title":"Chin. J. Pain Med."},{"key":"B73","doi-asserted-by":"publisher","first-page":"3615","DOI":"10.3969\/j.issn.1673-7202.2021.24.009","article-title":"Qigong for fibromyalgia syndrome: a systematic review and meta-analysis of randomized clinical trials","volume":"16","author":"Yapeng","year":"2021","journal-title":"World Chin. Med."},{"key":"B74","doi-asserted-by":"publisher","first-page":"790","DOI":"10.3969\/j.issn.2095-5227.2021.08.002","article-title":"Practice guideline of exercise intervention for patients with fibromyalgia (2021)","volume":"42","author":"Ye","year":"2021","journal-title":"Acad. J. Chin. PLA Med. Sch."},{"key":"B75","doi-asserted-by":"publisher","first-page":"1054","DOI":"10.3969\/j.issn.2095-7130.2019.01.019","article-title":"Effect of acupuncture on the sleep and life quality in the fibromyalgia syndrome patients","volume":"6","author":"Yiru","year":"2019","journal-title":"World J. Sleep Med."},{"key":"B76","doi-asserted-by":"publisher","first-page":"890","DOI":"10.1002\/msc.1766","article-title":"How durable are the effects of cognitive-behavioural therapy in controlling fibromyalgia symptoms? A prospective cohort study","volume":"21","author":"Zabihiyeganeh","year":"2023","journal-title":"Musculoskelet. Care"},{"key":"B77","doi-asserted-by":"publisher","first-page":"2058","DOI":"10.3760\/cma.j.issn.0366-6999.2010.15.019","article-title":"Epidemiologic study of soft tissue rheumatism in Shantou and Taiyuan, China","volume":"123","author":"Zeng","year":"2010","journal-title":"Chin. Med. J. Engl."},{"key":"B78","doi-asserted-by":"publisher","first-page":"3639","DOI":"10.2147\/jpr.S384215","article-title":"Effect of exercise interventions on health-related quality of life in patients with fibromyalgia syndrome: a systematic review and network meta-analysis","volume":"15","author":"Zhang","year":"2022","journal-title":"J. Pain Res."},{"key":"B79","doi-asserted-by":"publisher","first-page":"2822","DOI":"10.3969\/j.issn.1006-5725.2023.21.022","article-title":"Effects of general practice mode combined with duloxetine on psychological status, sleep quality and serum cytokines in patients with fibromyalgia syndrome","volume":"39","author":"Zhian","year":"2023","journal-title":"J. Pract. Med."},{"key":"B80","doi-asserted-by":"publisher","first-page":"721","DOI":"10.3969\/j.issn.1006-9852.2021.10.001","article-title":"Fibromyalgia China expert consensus clinical diagnosis and treatment","volume":"27","author":"Zhu","year":"2021","journal-title":"Chin. J. pain Med."},{"key":"B81","doi-asserted-by":"publisher","first-page":"709","DOI":"10.2147\/cia.S113576","article-title":"Depression and chronic pain in the elderly: links and management challenges","volume":"12","author":"Zis","year":"2017","journal-title":"Clin. Interv. Aging"}],"container-title":["Frontiers in Physiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fphys.2024.1413038\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,24]],"date-time":"2024-11-24T12:22:57Z","timestamp":1732450977000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fphys.2024.1413038\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,19]]},"references-count":81,"alternative-id":["10.3389\/fphys.2024.1413038"],"URL":"https:\/\/doi.org\/10.3389\/fphys.2024.1413038","relation":{},"ISSN":["1664-042X"],"issn-type":[{"value":"1664-042X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,19]]},"article-number":"1413038"}}