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These lesions resemble those of various myopathies found in humans, such as Duchenne muscular dystrophy, Limb-girdle muscular dystrophy, and sarcopenia. Fibroadipogenic progenitors (FAPs) are interstitial muscle-resident mesenchymal stem cells that are named because of their ability to differentiate into both fibroblasts and adipocytes. This cell population has clearly been established to play a role in the development and progression of myopathies in mice and humans. Gene expression studies of wooden breast and other related disorders have implicated FAPs in broilers, but to our knowledge this cell population have not been characterized in chickens. In this review, we summarize the evidence that FAPs may be a novel, new target for interventions that reduce the incidence and development of chicken breast muscle myopathies.<\/jats:p>","DOI":"10.3389\/fphys.2024.1458151","type":"journal-article","created":{"date-parts":[[2024,8,15]],"date-time":"2024-08-15T20:49:30Z","timestamp":1723754970000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":7,"title":["Fibroadipogenic progenitors: a potential target for preventing breast muscle myopathies in broilers"],"prefix":"10.3389","volume":"15","author":[{"given":"Usuk","family":"Jung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minjeong","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brynn H.","family":"Voy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,8,13]]},"reference":[{"key":"B2","doi-asserted-by":"publisher","first-page":"3723","DOI":"10.1016\/j.psj.2020.03.026","article-title":"Evaluation of growth production factors as predictors of the incidence and severity of white striping and woody breast in broiler chickens","volume":"99","author":"Aguirre","year":"2020","journal-title":"Poult. 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