{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T21:38:59Z","timestamp":1773265139628,"version":"3.50.1"},"reference-count":27,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:00:00Z","timestamp":1773100800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Physiol."],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study investigated the clinical effects of cricothyroid membrane puncture (CMP) anesthesia surface anesthesia following anesthesia induction on elderly patients undergoing endotracheal intubation (ETI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Eighty elderly patients scheduled for general anesthesia with endotracheal intubation at our hospital from January to December 2023 were enrolled and randomly assigned (n = 40 each) to a study group or a control group. After intravenous anesthesia induction, the study group received 2% lidocaine via CMP for surface anesthesia, while the control group received no CMP administration. The incidence of coughing during extubation in the emergence phase, first-attempt intubation success, hypoxemia, hypotension, and vasoactive drug use were recorded. Hemodynamic parameters and adverse events were compared between groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      All patients achieved successful first-attempt intubation. There were no significant differences in hypoxemia incidence between groups (\n                      <jats:italic>P<\/jats:italic>\n                      &amp;gt; 0.05). The study group had lower rates of hypotension and vasoactive drug use compared with the control group (\n                      <jats:italic>P<\/jats:italic>\n                      &amp;lt; 0.05), as well as a lower incidence of coughing during extubation (\n                      <jats:italic>P<\/jats:italic>\n                      &amp;lt; 0.05). At T0, heart rate (HR), systolic blood pressure (SBP), mean arterial pressure (MAP), and SpO\n                      <jats:sub>2<\/jats:sub>\n                      did not differ significantly (\n                      <jats:italic>P<\/jats:italic>\n                      &amp;gt; 0.05). At T1-T3, HR, SBP, and MAP were significantly lower in the study group (\n                      <jats:italic>P<\/jats:italic>\n                      &amp;lt; 0.05), with no significant differences in SpO\n                      <jats:sub>2<\/jats:sub>\n                      (\n                      <jats:italic>P<\/jats:italic>\n                      &amp;gt; 0.05). Total adverse event rates were similar between groups (\n                      <jats:italic>P<\/jats:italic>\n                      &amp;gt; 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>CMP surface anesthesia following anesthesia induction in elderly patients provides favorable clinical effects by improving hemodynamic stability and reducing coughing during emergence, without increasing adverse events.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fphys.2025.1600369","type":"journal-article","created":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T05:35:06Z","timestamp":1773207306000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of cricothyroid membrane puncture anesthesia on elderly patients undergoing endotracheal intubation after anesthesia induction: a clinical study"],"prefix":"10.3389","volume":"16","author":[{"given":"Yanbing","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, Chifeng Cancer Hospital","place":["Chifeng, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongchuan","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Chifeng Cancer Hospital","place":["Chifeng, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanjiao","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Chifeng Cancer Hospital","place":["Chifeng, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoli","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Chifeng Cancer Hospital","place":["Chifeng, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao","family":"Bi","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Chifeng Cancer Hospital","place":["Chifeng, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Lian","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology, Chifeng Cancer Hospital","place":["Chifeng, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,3,11]]},"reference":[{"key":"B1","article-title":"Tracheal intubation medications","volume-title":"StatPearls. 2024: treasure island (FL) ineligible companies","author":"Allen","year":"2023"},{"key":"B2","first-page":"194","article-title":"Fibreoptic intubation in awake patients","volume":"42","author":"Andruszkiewicz","year":"2010","journal-title":"Anestezjol. 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