{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T04:45:21Z","timestamp":1776746721951,"version":"3.51.2"},"reference-count":40,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T00:00:00Z","timestamp":1776729600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Physiol."],"abstract":"\n Background<\/jats:title>\n Ankle sprains are common in physically active populations and may progress to functional ankle instability, which can impair gait. Excess body mass increases lower-limb loading and may further compromise walking function in this population.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n To examine whether overweight status influences spatiotemporal gait parameters, gait deviation\/variability indices, and sagittal-plane hip, knee, and ankle biomechanics during level walking in individuals with functional ankle instability.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n In this cross-sectional comparative analysis, forty-four adults with functional ankle instability were enrolled (22 normal-weight and 22 overweight). Three-dimensional motion analysis was used during self-selected speed walking to quantify spatiotemporal parameters, gait deviation\/variability indices, and sagittal-plane hip, knee, and ankle kinematics and kinetics. Multiple comparisons across gait outcomes were controlled using a Holm-Bonferroni correction (family-wise error rate 0.05).<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n After Holm\u2013Bonferroni correction, spatiotemporal parameters did not differ significantly between groups. For gait deviation\/variability indices, several measures showed nominal (unadjusted) between-group differences, but none remained significant after correction. For discrete sagittal-plane biomechanics, the overweight group demonstrated lower peak hip flexion after correction (P_adj &lt; 0.05), whereas hip flexion at toe-off showed a nominal difference but did not remain significant after correction (P_adj \u2265 0.05).<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n After multiplicity control, overweight status was mainly associated with reduced hip flexion-related mechanics rather than consistent spatiotemporal or deviation\/variability alterations in adults with functional ankle instability.<\/jats:p>\n <\/jats:sec>","DOI":"10.3389\/fphys.2026.1710727","type":"journal-article","created":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T04:21:34Z","timestamp":1776745294000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of overweight on spatiotemporal gait parameters and lower-limb biomechanics in functional ankle instability"],"prefix":"10.3389","volume":"17","author":[{"given":"Dunbing","family":"Huang","sequence":"first","affiliation":[{"name":"Encephalopathy and Rehabilitation Center, The Second Affiliated Hospital of Zhejiang Chinese Medical University","place":["Hangzhou, Zhejiang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chen","family":"Zhang","sequence":"additional","affiliation":[{"name":"Rehabilitation Medicine Department, The Third Affiliated Hospital of Zhejiang Chinese Medical University","place":["Hangzhou, Zhejiang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiaqi","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Shanghai Fourth People\u2019s Hospital, School of Medicine, Tongji University","place":["Shanghai, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongfei","family":"Ren","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Shanghai Fourth People\u2019s Hospital, School of Medicine, Tongji University","place":["Shanghai, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhenhua","family":"Wu","sequence":"additional","affiliation":[{"name":"Encephalopathy and Rehabilitation Center, The Second Affiliated Hospital of Zhejiang Chinese Medical University","place":["Hangzhou, Zhejiang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lihong","family":"Li","sequence":"additional","affiliation":[{"name":"Encephalopathy and Rehabilitation Center, The Second Affiliated Hospital of Zhejiang Chinese Medical University","place":["Hangzhou, Zhejiang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaohua","family":"Ke","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Shanghai Fourth People\u2019s Hospital, School of Medicine, Tongji University","place":["Shanghai, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhonghua","family":"Lin","sequence":"additional","affiliation":[{"name":"Rehabilitation Medicine Center, Fuzhou University Affiliated Provincial Hospital","place":["Fuzhou, China"]},{"name":"Rehabilitation Medicine Center, Shengli Clinical Medical College of Fujian Medical University","place":["Fuzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cai","family":"Jiang","sequence":"additional","affiliation":[{"name":"Rehabilitation Medicine Center, Fuzhou University Affiliated Provincial Hospital","place":["Fuzhou, China"]},{"name":"Rehabilitation Medicine Center, Shengli Clinical Medical College of Fujian Medical University","place":["Fuzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,4,21]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1016\/j.gaitpost.2024.06.024","article-title":"Effects of overweight and obesity on lower limb walking characteristics from joint kinematics to muscle activations","volume":"113","author":"Adouni","year":"2024","journal-title":"Gait Post"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1296","DOI":"10.4085\/1062-6050-550-17","article-title":"Hop-stabilization training and landing biomechanics in athletes with chronic ankle instability: A randomized controlled trial","volume":"54","author":"Ardakani","year":"2019","journal-title":"J. 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