{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T11:18:58Z","timestamp":1788520738416,"version":"build-2803163510"},"reference-count":80,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:00:00Z","timestamp":1788480000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Physiol."],"abstract":"<jats:p>Allergic rhinitis (AR) is a prevalent chronic noninfectious inflammatory disorder. Emerging evidence suggests that the gut microbiota, as a central component of the human microecological system, plays an important role in the development and progression of AR through the gut\u2013nasal axis. Chinese herbal medicine (CHM) has been shown to improve clinical symptoms and quality of life in patients with AR, and these therapeutic benefits may be related to its capacity to modulate gut microbial composition and activity. This review outlines the effects of CHM on the gut microbiota in AR and further explores the possible mechanisms involved.<\/jats:p>","DOI":"10.3389\/fphys.2026.1900200","type":"journal-article","created":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T10:50:27Z","timestamp":1788519027000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Gut microbiota as a therapeutic target of Chinese herbal medicine in allergic rhinitis: the gut\u2013nasal axis and immunity"],"prefix":"10.3389","volume":"17","author":[{"given":"Ziye","family":"Huang","sequence":"first","affiliation":[{"name":"Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Sun","sequence":"additional","affiliation":[{"name":"Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,4]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2025.1607388","article-title":"Gut microbiota: a promising new target in immune tolerance","volume":"16","author":"Almansour","year":"2025","journal-title":"Front. 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