{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T05:04:36Z","timestamp":1790053476062,"version":"4.0.1"},"reference-count":46,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:00:00Z","timestamp":1790035200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Physiol."],"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>This study aimed to investigate the relationship between the isocapnic buffering (IB) phase and maximal accumulated oxygen deficit (MAOD) in athletes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Twenty-two active male athletes (19.7 \u00b1 1.4 years) participated in an incremental test to determine maximal oxygen uptake (V\u0307O\n                      <jats:sub>2max<\/jats:sub>\n                      ), the intensity associated with V\u0307O\n                      <jats:sub>2max<\/jats:sub>\n                      (vVO\n                      <jats:sub>2max<\/jats:sub>\n                      ), the anaerobic threshold (AT), the respiratory compensation point (RCP), and IB, 6 submaximal efforts to construct the V\u0307O\n                      <jats:sub>2<\/jats:sub>\n                      -velocity relationship, a supramaximal effort to determine MAOD, and the Wingate Anaerobic test. The IB was calculated as the difference in both oxygen uptake (IB\n                      <jats:sub>VO2<\/jats:sub>\n                      ) and running velocity (IBv) between the RCP and AT, and expressed in absolute or relative values.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      MAOD was positively associated with absolute and relative IB\n                      <jats:sub>VO2<\/jats:sub>\n                      and IB\n                      <jats:sub>V<\/jats:sub>\n                      (rs=0.825, 0.753, 0.675, and 0.630, respectively; all Holm-adjusted p \u2264 0.002). In exploratory analyses, peak power remained associated after false discovery rate (FDR) adjustment with absolute and relative IB\n                      <jats:sub>VO2<\/jats:sub>\n                      , IB\n                      <jats:sub>V<\/jats:sub>\n                      , and MAOD (q \u2264 0.047), while mean power remained associated with absolute and relative IB\n                      <jats:sub>VO2<\/jats:sub>\n                      and MAOD (q \u2264 0.047). No statistically significant association was detected between V\u0307O\n                      <jats:sub>2max<\/jats:sub>\n                      and either MAOD or the IB phase.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>These findings suggest that the IB phase may be a potential physiological indicator associated with anaerobic capacity in athletes. A high buffering capacity may allow anaerobic glycolysis to persist longer, thereby providing greater anaerobic capacity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fphys.2026.1947289","type":"journal-article","created":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T04:24:00Z","timestamp":1790051040000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["The relationship between the isocapnic buffering phase and maximal accumulated oxygen deficit in athletes"],"prefix":"10.3389","volume":"17","author":[{"given":"Muhammed","family":"Ay","sequence":"first","affiliation":[{"name":"Department of Coaching Education, Faculty of Sports Sciences, University of Esenyurt","place":["Istanbul, T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selcen","family":"Korkmaz Ery\u0131lmaz","sequence":"additional","affiliation":[{"name":"Department of Physical Education and Sports Teaching, Faculty of Sports Sciences, University of Cukurova","place":["Adana, T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Burcu","family":"\u00d6zdemir","sequence":"additional","affiliation":[{"name":"Department of Coaching Education, Faculty of Sports Sciences, University of Cukurova","place":["Adana, T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullah","family":"K\u0131lc\u0131","sequence":"additional","affiliation":[{"name":"Department of Coaching Education, Faculty of Sports Sciences, University of Cukurova","place":["Adana, T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d6mer Cumhur","family":"Boyraz","sequence":"additional","affiliation":[{"name":"Department of Coaching Education, Faculty of Sports Sciences, University of Cukurova","place":["Adana, T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d6zg\u00fcr","family":"G\u00fcna\u015ft\u0131","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Medicine, University of Cukurova","place":["Adana, T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa O\u011fuzhan","family":"Akbulut","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Medicine, University of Cukurova","place":["Adana, T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c7i\u011fdem","family":"\u00d6zdemir Postall\u0131","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Medicine, University of Cukurova","place":["Adana, T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ertu\u011frul","family":"Gezgin","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Medicine, University of Cukurova","place":["Adana, T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erkan","family":"Tiyekli","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, University of Cukurova","place":["Adana, T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerem","family":"\u00d6zg\u00fcnen","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Medicine, University of Cukurova","place":["Adana, T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanl\u0131 Sadi","family":"Kurdak","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Medicine, University of Cukurova","place":["Adana, T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,22]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1113\/jphysiol.1990.sp018000","article-title":"Anaerobic energy production and O2 deficit\u2010debt relationship during exhaustive exercise in humans","volume":"422","author":"Bangsbo","year":"1990","journal-title":"J. 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