{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:17:23Z","timestamp":1753892243045,"version":"3.41.2"},"reference-count":78,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,11,21]],"date-time":"2022-11-21T00:00:00Z","timestamp":1668988800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Plant Sci."],"abstract":"<jats:p>Plant height affects crop production and breeding practices, while genetic control of dwarfism draws a broad interest of researchers. Dwarfism in soybean (<jats:italic>Glycine max<\/jats:italic>) is mainly unexplored. Here, we characterized a dwarf mutant <jats:italic>dm<\/jats:italic> screened from ethyl methanesulfonate (EMS) mutated seeds of the soybean cultivar Zhongpin 661(ZP). Phenotypically, <jats:italic>dm<\/jats:italic> showed shorter and thinner stems, smaller leaves, and more nodes than ZP under greenhouse conditions. Genetically, whole-genome sequencing and comparison revealed that 210K variants of SNPs and InDel in ZP relative to the soybean reference genome Williams82, and EMS mutagenesis affected 636 genes with variants predicted to have a large impact on protein function in <jats:italic>dm<\/jats:italic>. Whole-genome methylation sequencing found 704 differentially methylated regions in <jats:italic>dm<\/jats:italic>. Further whole-genome RNA-Seq based transcriptomic comparison between ZP and <jats:italic>dm<\/jats:italic> leaves revealed 687 differentially expressed genes (DEGs), including 263 up-regulated and 424 down-regulated genes. Integrated omics analyses revealed 11 genes with both differential expressions and DNA variants, one gene with differential expression and differential methylation, and three genes with differential methylation and sequence variation, worthy of future investigation. Genes in cellulose, fatty acids, and energy-associated processes could be the key candidate genes for the dwarf phenotype. This study provides genetic clues for further understanding of the genetic control of dwarfism in soybean. The genetic resources could help to inbreed new cultivars with a desirable dwarf characteristic.<\/jats:p>","DOI":"10.3389\/fpls.2022.1017672","type":"journal-article","created":{"date-parts":[[2022,11,21]],"date-time":"2022-11-21T17:06:25Z","timestamp":1669050385000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Genetic dissection of the soybean dwarf mutant dm with integrated genomic, transcriptomic and methylomic analyses"],"prefix":"10.3389","volume":"13","author":[{"given":"Jian","family":"Song","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuewen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lan","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhongfeng","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Honglei","family":"Ren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2022,11,21]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0191492","article-title":"Differential DNA methylation and transcription profiles in date palm roots exposed to salinity","volume":"13","author":"Al Harrasi","year":"2018","journal-title":"PloS One"},{"key":"B2","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1016\/j.molp.2018.02.003","article-title":"Relationships between gene structure and genome instability in flowering plants","volume":"11","author":"Bennetzen","year":"2018","journal-title":"Mol. Plant"},{"key":"B3","doi-asserted-by":"publisher","first-page":"1350","DOI":"10.1104\/pp.113.233312","article-title":"Differential methylation during maize leaf growth targets developmentally regulated genes","volume":"164","author":"Candaele","year":"2014","journal-title":"Plant Physiol."},{"key":"B4","doi-asserted-by":"publisher","first-page":"2228","DOI":"10.1016\/S2095-3119(15)61312-0","article-title":"Characterization of dwarf mutants and molecular mapping of a dwarf locus in soybean","volume":"15","author":"Cheng","year":"2016","journal-title":"J. Integr. Agriculture."},{"key":"B5","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1038\/nature06745","article-title":"Shotgun bisulphite sequencing of the arabidopsis genome reveals DNA methylation patterning","volume":"452","author":"Cokus","year":"2008","journal-title":"Nature."},{"key":"B6","doi-asserted-by":"publisher","first-page":"593","DOI":"10.2135\/cropsci1995.0011183X003500020060x","article-title":"Registration of 'Charleston' soybean","volume":"35","author":"Cooper","year":"1995","journal-title":"Crop Science."},{"key":"B7","doi-asserted-by":"publisher","first-page":"1563","DOI":"10.2135\/cropsci2003.1563","article-title":"Registration of 'Apex' soybean","volume":"43","author":"Cooper","year":"2003","journal-title":"Crop Science."},{"key":"B8","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1104\/PP.112.205369","article-title":"Tnt1 retrotransposon mutagenesis: A tool for soybean functional genomics","volume":"161","author":"Cui","year":"2013","journal-title":"Plant Physiol."},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2017.01789","article-title":"The FAD2 gene in plants: Occurrence, regulation, and role","volume":"8","author":"Dar","year":"2017","journal-title":"Front. Plant Science."},{"key":"B10","doi-asserted-by":"publisher","first-page":"618","DOI":"10.1111\/tpj.12234","article-title":"PpeTAC1 promotes the horizontal growth of branches in peach trees and is a member of a functionally conserved gene family found in diverse plants species","volume":"75","author":"Dardick","year":"2013","journal-title":"Plant J."},{"key":"B11","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1007\/s10681-020-02633-7","article-title":"Identification and molecular mapping of the semi-dwarf locus (sdf-1) in soybean by SLAF-seq method","volume":"216","author":"Dong","year":"2020","journal-title":"Euphytica"},{"volume-title":"National standard of the people's republic of China: Determination of acid detergent lignin in feedstuffs","year":"2006","key":"B12"},{"volume-title":"National standard of the people's republic of China: Determination of neutral detergent fiber in feedstuffs","year":"2006","key":"B13"},{"volume-title":"National standard of the people's republic of China: Feeding stuffs-determination of crude fiber content-method with intermediate filtration","year":"2006","key":"B14"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1186\/1746-4811-9-16","article-title":"High-throughput sequencing of cytosine methylation in plant DNA","volume":"9","author":"Hardcastle","year":"2013","journal-title":"Plant Methods"},{"key":"B16","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1016\/S0168-9525(02)00009-4","article-title":"The genes of the green revolution","volume":"19","author":"Hedden","year":"2003","journal-title":"Trends Genet."},{"key":"B17","doi-asserted-by":"publisher","first-page":"2680","DOI":"10.1105\/tpc.110.075549","article-title":"Characterization of the molecular mechanism underlying gibberellin perception complex formation in rice","volume":"22","author":"Hirano","year":"2010","journal-title":"Plant Cell."},{"key":"B18","doi-asserted-by":"publisher","first-page":"1313","DOI":"10.1104\/pp.123.4.1313","article-title":"A comparative analysis of the plant cellulose synthase (CesA) gene family","volume":"123","author":"Holland","year":"2000","journal-title":"Plant Physiol."},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2019.01468","article-title":"Induced genetic variation in crop plant by random or targeted mutagenesis:convergence and differences","volume":"10","author":"Holme","year":"2019","journal-title":"Front. Plant Science."},{"key":"B20","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1007\/s10681-014-1295-x","article-title":"Genome-wide analysis of mutations in a dwarf soybean mutant induced by fast neutron bombardment","volume":"203","author":"Hwang","year":"2015","journal-title":"Euphytica."},{"key":"B21","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1023\/B:PLAN.0000038261.21060.47","article-title":"A rice semi-dwarf gene, tan-ginbozu (D35), encodes the gibberellin biosynthesis enzyme, ent-kaurene oxidase","volume":"54","author":"Itoh","year":"2004","journal-title":"Plant Mol. Biol."},{"key":"B22","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1111\/pbi.12133","article-title":"Genomewide discovery of DNA polymorphisms in rice cultivars with contrasting drought and salinity stress response and their functional relevance","volume":"12","author":"Jain","year":"2014","journal-title":"Plant Biotechnol. J."},{"key":"B23","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1038\/35093585","article-title":"Green revolution: the way forward","volume":"2","author":"Khush","year":"2001","journal-title":"Nat. Rev. Genet."},{"key":"B24","doi-asserted-by":"publisher","first-page":"R36","DOI":"10.1186\/gb-2013-14-4-r36","article-title":"TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions","volume":"14","author":"Kim","year":"2013","journal-title":"Genome Biol."},{"key":"B25","doi-asserted-by":"publisher","first-page":"1571","DOI":"10.1093\/bioinformatics\/btr167","article-title":"Bismark: a flexible aligner and methylation caller for bisulfite-seq applications","volume":"27","author":"Krueger","year":"2011","journal-title":"Bioinformatics"},{"key":"B26","doi-asserted-by":"publisher","first-page":"20226","DOI":"10.1073\/pnas.1907379116","article-title":"Arabidopsis h(+)-ATPase AHA1 controls slow wave potential duration and wound-response jasmonate pathway activation","volume":"116","author":"Kumari","year":"2019","journal-title":"Proc. Natl. Acad. Sci. United States America."},{"key":"B27","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1007\/s10142-007-0057-4","article-title":"Genomic targeting and mapping of tiller inhibition gene (tin3) of wheat using ESTs and synteny with rice","volume":"8","author":"Kuraparthy","year":"2008","journal-title":"Funct. Integr. Genomics"},{"key":"B28","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1038\/nmeth.1923","article-title":"Fast gapped-read alignment with bowtie 2","volume":"9","author":"Langmead","year":"2012","journal-title":"Nat. Methods"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2021.702930","article-title":"Increasing monounsaturated fatty acid contents in hexaploid camelina sativa seed oil by FAD2 gene knockout using CRISPR-Cas9","volume":"12","author":"Lee","year":"2021","journal-title":"Front. Plant Science."},{"key":"B30","doi-asserted-by":"publisher","first-page":"1754","DOI":"10.1093\/bioinformatics\/btp324","article-title":"Fast and accurate short read alignment with burrows-wheeler transform","volume":"25","author":"Li","year":"2009","journal-title":"Bioinformatics."},{"key":"B31","doi-asserted-by":"publisher","first-page":"1001","DOI":"10.1007\/s00122-017-3044-8","article-title":"Identification of the dwarf gene GmDW1 in soybean ( Glycine max l.) by combining mapping-by-sequencing and linkage analysis","volume":"131","author":"Li","year":"2018","journal-title":"Theor. Appl. Genet."},{"key":"B32","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1111\/jipb.12505","article-title":"Development and utilization of a new chemically-induced soybean library with a high mutation density","volume":"59","author":"Li","year":"2017","journal-title":"J. Integr. Plant Biol."},{"key":"B33","doi-asserted-by":"publisher","first-page":"955","DOI":"10.1007\/s00438-014-0964-8","article-title":"Genome re-sequencing and bioinformatics analysis of a nutraceutical rice","volume":"290","author":"Lin","year":"2015","journal-title":"Mol. Genet. Genomics"},{"key":"B34","doi-asserted-by":"publisher","first-page":"2077","DOI":"10.1126\/science.1059745","article-title":"Requirement of CHROMOMETHYLASE3 for maintenance of CpXpG methylaton","volume":"292","author":"Lindroth","year":"2001","journal-title":"Science."},{"key":"B35","doi-asserted-by":"publisher","first-page":"1512","DOI":"10.1105\/tpc.109.065987","article-title":"DWARF27, an iron-containing protein required for the biosynthesis of strigolactones, regulates rice tiller bud outgrowth","volume":"21","author":"Lin","year":"2009","journal-title":"Plant Cell."},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1126\/science.1237905","article-title":"Global epigenomic reconfiguration during mammalian brain development","volume":"341","author":"Lister","year":"2013","journal-title":"Science."},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0180662","article-title":"Genome wide re-sequencing of newly developed rice lines from common wild rice (Oryza rufipogon griff.) for the identification of NBS-LRR genes","volume":"12","author":"Liu","year":"2017","journal-title":"PloS One"},{"key":"B38","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1016\/j.molp.2020.03.002","article-title":"Toward a \"Green revolution\" for soybean","volume":"13","author":"Liu","year":"2020","journal-title":"Mol. Plant"},{"key":"B39","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1007\/s00122-013-2213-7","article-title":"Characterization and genetic mapping of a photoperiod-sensitive dwarf 1 locus in rice (Oryza sativa l.)","volume":"127","author":"Li","year":"2014","journal-title":"Theor. Appl. Genet."},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0201854","article-title":"Genome-wide analysis of DNA polymorphisms, the methylome and transcriptome revealed that multiple factors are associated with low pollen fertility in autotetraploid rice","volume":"13","author":"Li","year":"2018","journal-title":"PloS One"},{"key":"B41","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1093\/plphys\/kiaa065","article-title":"Dynamic membranes: the multiple roles of P4 and P5 ATPases","volume":"185","author":"L\u00f3pez-Marqu\u00e9s","year":"2020","journal-title":"Plant Physiol."},{"key":"B42","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1146\/annurev-arplant-050213-040240","article-title":"The cell biology of cellulose synthesis","volume":"65","author":"Mcfarlane","year":"2014","journal-title":"Annu. Rev. Plant Biol."},{"key":"B43","doi-asserted-by":"publisher","first-page":"1297","DOI":"10.1101\/gr.107524.110","article-title":"The genome analysis toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data","volume":"20","author":"Mckenna","year":"2010","journal-title":"Genome Res."},{"key":"B44","doi-asserted-by":"publisher","first-page":"1196","DOI":"10.1017\/S0021859619000182","article-title":"Discovery of mutations in chenopodium quinoa willd through EMS mutagenesis and mutation screening using pre-selection phenotypic data and next-generation sequencing","volume":"156","author":"Mestanza","year":"2019","journal-title":"J. Agric. Science."},{"key":"B45","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1093\/plphys\/kiac228","article-title":"miR778 mediates gene expression, histone modification, and DNA methylation during cyst nematode parasitism","volume":"4","author":"Morgan","year":"2022","journal-title":"Plant Physiol."},{"key":"B46","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1038\/nmeth.1226","article-title":"Mapping and quantifying mammalian transcriptomes by RNA-seq","volume":"5","author":"Mortazavi","year":"2008","journal-title":"Nat. Methods"},{"key":"B47","doi-asserted-by":"publisher","first-page":"1514","DOI":"10.1104\/pp.103.034025","article-title":"Differential expression of vacuolar h+-ATPase subunit c genes in tissues active in membrane trafficking and their roles in plant growth as revealed by RNAi","volume":"134","author":"Padmanaban","year":"2004","journal-title":"Plant Physiol."},{"key":"B48","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1038\/22307","article-title":"'Green revolution' genes encode mutant gibberellin response modulators","volume":"400","author":"Peng","year":"1999","journal-title":"Nature."},{"key":"B49","doi-asserted-by":"publisher","first-page":"846","DOI":"10.1093\/embo-reports\/kvf177","article-title":"Plant architecture","volume":"3","author":"Reinhardt","year":"2002","journal-title":"EMBO Rep."},{"key":"B50","doi-asserted-by":"publisher","first-page":"e19","DOI":"10.5808\/gi.21024","article-title":"Analysis of genome variants in dwarf soybean lines obtained in F6 derived from cross of normal parents (cultivated and wild soybean)","volume":"19","author":"Roy","year":"2021","journal-title":"Genomics Informatics."},{"key":"B51","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1111\/j.1365-313x.2009.03809.x","article-title":"Shoot apical meristem function in arabidopsis requires the combined activities of three BEL1-like homeodomain proteins","volume":"58","author":"Rutjens","year":"2010","journal-title":"Plant J."},{"key":"B52","doi-asserted-by":"publisher","first-page":"766","DOI":"10.1093\/pcp\/pcs008","article-title":"DNA Methylation in plants: relationship to small RNAs and histone modifications, and functions in transposon inactivation","volume":"53","author":"Saze","year":"2012","journal-title":"Plant Cell Physiol."},{"key":"B53","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1038\/nature08670","article-title":"Genome sequence of the palaeopolyploid soybean","volume":"463","author":"Schmutz","year":"2010","journal-title":"Nature."},{"key":"B54","doi-asserted-by":"publisher","first-page":"3259","DOI":"10.1101\/gad.13.24.3259","article-title":"The arabidopsis det3 mutant reveals a central role for the vacuolar h(+)-ATPase in plant growth and development","volume":"13","author":"Schumacher","year":"1999","journal-title":"Genes Dev."},{"key":"B55","doi-asserted-by":"publisher","first-page":"817","DOI":"10.1038\/nmeth.3035","article-title":"Single-cell genome-wide bisulfite sequencing for assessing epigenetic heterogeneity","volume":"11","author":"Smallwood","year":"2014","journal-title":"Nat. Methods"},{"key":"B56","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1038\/nsmb.2735","article-title":"Non-CG methylation patterns shape the epigenetic landscape in arabidopsis","volume":"21","author":"Stroud","year":"2014","journal-title":"Nat. Struct. Mol. Biol."},{"key":"B57","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1016\/j.cub.2011.02.036","article-title":"The molecular mechanism and evolution of the GA\u2013GID1\u2013DELLA signaling module in plants","volume":"21","author":"Sun","year":"2011","journal-title":"Curr. Biol."},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23158643","article-title":"GmIAA27 encodes an AUX\/IAA protein involved in dwarfing and multi-branching in soybean","volume":"23","author":"Su","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"B59","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1111\/j.1365-313X.2009.03825.x","article-title":"DWARF AND LOW-TILLERING, a new member of the GRAS family, plays positive roles in brassinosteroid signaling in rice","volume":"58","author":"Tong","year":"2010","journal-title":"Plant J. Cell Mol. Biol."},{"key":"B60","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1038\/nprot.2014.114","article-title":"MethylC-seq library preparation for base-resolution whole-genome bisulfite sequencing","volume":"10","author":"Urich","year":"2015","journal-title":"Nat. Protoc."},{"key":"B61","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1038\/s41597-021-00834-w","article-title":"Genetic variation among 481 diverse soybean accessions, inferred from genomic re-sequencing","volume":"8","author":"Valliyodan","year":"2021","journal-title":"Sci. Data."},{"key":"B62","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1093\/bioinformatics\/btp612","article-title":"DEGseq: an r package for identifying differentially expressed genes from RNA-seq data","volume":"26","author":"Wang","year":"2010","journal-title":"Bioinf. Oxford."},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.48130\/BPR-2022-0002","article-title":"An integrative analysis of metabolomics, DNA methylation and RNASeq data reveals key genes involved in albino tea 'Haishun 2'","volume":"2","author":"Wei","year":"2022","journal-title":"Beverage Plant Res."},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22158192","article-title":"Genome-wide association study in rice revealed a novel gene in determining plant height and stem development, by encoding a WRKY transcription factor","volume":"15","author":"Wei","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2020.594798","article-title":"Characterization of two new brown midrib1 mutations from an EMS-mutagenic maize population for lignocellulosic biomass utilization","volume":"11","author":"Xiong","year":"2020","journal-title":"Front. Plant Science."},{"key":"B66","doi-asserted-by":"publisher","first-page":"2907","DOI":"10.1007\/s00122-022-04158-0","article-title":"The brassinosteroid biosynthesis gene TaD11-2A controls grain size and its elite haplotype improves wheat grain yields","volume":"135","author":"Xu","year":"2022","journal-title":"Theor. Appl. Genet."},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2016.0205","article-title":"Simultaneous identification of multiple causal mutations in rice","volume":"7","author":"Yan","year":"2017","journal-title":"Front. Plant Science."},{"key":"B68","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1093\/mp\/ssr020","article-title":"The mechanisms of brassinosteroids' action: from signal transduction to plant development","volume":"4","author":"Yang","year":"2011","journal-title":"Mol. Plant"},{"key":"B69","doi-asserted-by":"publisher","first-page":"R14","DOI":"10.1186\/gb-2010-11-2-r14","article-title":"Gene ontology analysis for RNA-seq: accounting for selection bias","volume":"11","author":"Young","year":"2010","journal-title":"Genome Biol."},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.1016\/j.egg.2022.100115","article-title":"OsFBK4, a novel GA insensitive gene positively regulates plant height in rice (Oryza sativa l.)","volume":"23","author":"Zegeye","year":"2022","journal-title":"Ecol. Genet. Genomics"},{"key":"B71","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1038\/s41580-018-0016-z","article-title":"Dynamics and function of DNA methylation in plants","volume":"19","author":"Zhang","year":"2018","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"B72","doi-asserted-by":"publisher","first-page":"S70","DOI":"10.1017\/s1479262114000306","article-title":"Genome-wide expression analysis in a dwarf soybean mutant","volume":"12","author":"Zhang","year":"2014","journal-title":"Plant Genet. Resources."},{"key":"B73","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1101\/gr.155879.113","article-title":"Genome-wide high resolution parental-specific DNA and histone methylation maps uncover patterns of imprinting regulation in maize","volume":"24","author":"Zhang","year":"2014","journal-title":"Genome Res."},{"key":"B74","doi-asserted-by":"publisher","first-page":"1435","DOI":"10.1007\/s00122-019-03290-8","article-title":"Identification and characterization of a new dwarf locus DS-4 encoding an Aux\/IAA7 protein in Brassica napus","volume":"132","author":"Zhao","year":"2019","journal-title":"Theor. Appl. Genet."},{"key":"B75","doi-asserted-by":"publisher","first-page":"1","DOI":"10.21203\/rs.3.rs-263682\/v1","article-title":"Bulked segregant analysis coupled with whole-genome sequencing (BSA-seq) and identification of a novel locus, qGL3.5, that regulates grain length","author":"Zhao","year":"2021","journal-title":"Res. Square"},{"key":"B76","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1038\/nature16537","article-title":"D14\u2013SCFD3-dependent degradation of D53 regulates strigolactone signalling","volume":"532","author":"Zhou","year":"2015","journal-title":"Nature."},{"key":"B77","doi-asserted-by":"publisher","DOI":"10.1038\/srep29718","article-title":"Dissection of genetic architecture of rice plant height and heading date by multiple-strategy-based association studies","volume":"6","author":"Zhou","year":"2016","journal-title":"Sci. Rep."},{"key":"B78","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1038\/sj.cr.7290272","article-title":"Characterization of a novel developmentally retarded mutant (drm1) associated with the autonomous flowering pathway in arabidopsis","volume":"15","author":"Zhu","year":"2005","journal-title":"Cell Res."}],"container-title":["Frontiers in Plant Science"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpls.2022.1017672\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,21]],"date-time":"2022-11-21T17:06:30Z","timestamp":1669050390000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpls.2022.1017672\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,21]]},"references-count":78,"alternative-id":["10.3389\/fpls.2022.1017672"],"URL":"https:\/\/doi.org\/10.3389\/fpls.2022.1017672","relation":{},"ISSN":["1664-462X"],"issn-type":[{"type":"electronic","value":"1664-462X"}],"subject":[],"published":{"date-parts":[[2022,11,21]]},"article-number":"1017672"}}