{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T16:53:54Z","timestamp":1792601634888,"version":"4.5.0"},"reference-count":105,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,7,22]],"date-time":"2022-07-22T00:00:00Z","timestamp":1658448000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31372088"],"award-info":[{"award-number":["31372088"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31772333"],"award-info":[{"award-number":["31772333"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Plant Sci."],"abstract":"<jats:p>Fusarium wilt is one of the most destructive and less controllable diseases in melon, which is usually caused by<jats:italic>fusarium oxysporum<\/jats:italic>. In this study, transcriptome sequencing and Yeast Two-Hybrid (Y2H) methods were used for quantification of differentially expressed genes (DEGs) involved in<jats:italic>fusarium oxysporum<\/jats:italic>(f. sp.<jats:italic>melonis<\/jats:italic>race 1) stress-induced mechanisms in contrasted melon varieties (M4-45 \u201csusceptible\u201d and MR-1 \u201cresistant\u201d). The interaction factors of<jats:italic>Fom-2<\/jats:italic>resistance genes were also explored in response to the plant-pathogen infection mechanism. Transcriptomic analysis exhibited total 1,904 new genes; however, candidate DEGs analysis revealed a total of 144 specific genes (50 upregulated and 94 downregulated) for M4-45 variety and 104 specific genes (71 upregulated and 33 downregulated) for MR-1 variety, respectively. The analysis of Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway depicted some candidate DEGs, including Phenylalanine metabolism, phenylpropane biosynthesis, plants-pathogen interaction, and signal transduction of plant hormones, which were mainly involved in disease resistance metabolic pathways. The weighted gene co-expression network analysis (WGCNA) analysis revealed a strong correlation module and exhibited the disease resistance-related genes encoding course proteins, transcription factors, protein kinase, benzene propane biosynthesis path, plants-pathogen interaction pathway, and glutathione S-transferase. Meanwhile, the resistance-related specific genes expression was relatively abundant in MR-1 compared to the M4-45, and cell wall-associated receptor kinases (<jats:italic>MELO3C008452<\/jats:italic>and<jats:italic>MELO3C008453<\/jats:italic>), heat shock protein (Cucumis_melo_newGene_172), defensin-like protein (Cucumis_melo_newGene_5490), and disease resistance response protein (<jats:italic>MELO3C016325<\/jats:italic>), activator response protein (<jats:italic>MELO3C021623<\/jats:italic>), leucine-rich repeat receptor protein kinase (<jats:italic>MELO3C024412<\/jats:italic>), lactyl glutathione ligase (Cucumis_melo_newGene_36), and unknown protein (<jats:italic>MELO3C007588<\/jats:italic>) were persisted by exhibiting the upregulated expressions. At the transcription level, the interaction factors between the candidate genes in response to the<jats:italic>fusarium oxysporum<\/jats:italic>induced stress, and Y2H screening signified the main contribution of MYB transcription factors (<jats:italic>MELO3C009678<\/jats:italic>and<jats:italic>MELO3C014597<\/jats:italic>), BZIP (<jats:italic>MELO3C011839<\/jats:italic>and<jats:italic>MELO3C019349<\/jats:italic>), unknown proteins, and key enzymes in the ubiquitination process (<jats:italic>4XM334FK014<\/jats:italic>). The candidate genes were further verified in exogenously treated melon plants with<jats:italic>f. oxysporum<\/jats:italic>(<jats:italic>Fom-2<\/jats:italic>, Race 1), Abscisic acid (ABA), Methyl Jasmonite (MeJA), and Salicylic acid (SA), using the fluorescence quantitative polymerase chain reaction (qRT-PCR) analysis. The overall expression results indicated that the SA signal pathway is involved in effective regulation of the<jats:italic>Fom-2<\/jats:italic>gene activity.<\/jats:p>","DOI":"10.3389\/fpls.2022.961586","type":"journal-article","created":{"date-parts":[[2022,7,22]],"date-time":"2022-07-22T13:32:37Z","timestamp":1658496757000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":18,"title":["Transcriptomic Analysis of Fusarium oxysporum Stress-Induced Pathosystem and Screening of Fom-2 Interaction Factors in Contrasted Melon Plants"],"prefix":"10.3389","volume":"13","author":[{"given":"Tiantian","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiajun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaomei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sikandar","family":"Amanullah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueyan","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingchong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanhang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feishi","family":"Luan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuezheng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,7,22]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"3389","DOI":"10.1093\/nar\/25.17.3389","article-title":"Gapped BLAST and PSI BLAST: a new generation of protein database search programs.","volume":"25","author":"Altschul","year":"1997","journal-title":"Nucleic Acids Res."},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2022.911846","article-title":"Antioxidative defense system, hormones, and metabolite accumulation in different plant parts of two contrasting rice cultivars as influenced by plant growth regulators under heat stress.","volume":"13","author":"Al-Zahrani","year":"2022","journal-title":"Front. Plant Sci."},{"key":"B3","doi-asserted-by":"publisher","first-page":"2083","DOI":"10.1007\/s12298-021-01062-7","article-title":"Biochar coupling with phosphorus fertilization modifies antioxidant activity, osmolyte accumulation and reactive oxygen species synthesis in the leaves and xylem sap of rice cultivars under high-temperature stress.","volume":"27","author":"Atif","year":"2021","journal-title":"Physiol. Mol. Biol. Plants"},{"key":"B4","doi-asserted-by":"publisher","first-page":"960","DOI":"10.1105\/tpc.17.00060","article-title":"Multi-omics of tomato glandular trichomes reveals distinct features of central carbon metabolism supporting high productivity of specialized metabolites.","volume":"29","author":"Balcke","year":"2017","journal-title":"Plant Cell"},{"key":"B5","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1007\/s10528-013-9630-9","article-title":"Molecular characterization, 3d model analysis, and expression pattern of the cmubc gene encoding the melon ubiquitin-conjugating enzyme under drought and salt stress conditions.","volume":"52","author":"Baloglu","year":"2014","journal-title":"Biochem. Genet."},{"key":"B6","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1007\/s11103-008-9435-0","article-title":"Role of plant hormones in plant defence responses.","volume":"69","author":"Bari","year":"2009","journal-title":"Plant Mol. Biol."},{"key":"B7","doi-asserted-by":"publisher","first-page":"2114","DOI":"10.1093\/bioinformatics\/btu170","article-title":"Trimmomatic: a flexible trimmer for Illumina sequence data.","volume":"15","author":"Bolger","year":"2014","journal-title":"Bioinformatics"},{"key":"B8","doi-asserted-by":"publisher","first-page":"3809","DOI":"10.1094\/PDIS-12-20-2643-RE","article-title":"Quantitative trait loci mapping of resistance to powdery mildew race 1 in a recombinant inbred line population of melon.","volume":"105","author":"Branham","year":"2021","journal-title":"Plant Dis."},{"key":"B9","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1186\/1471-2164-14-178","article-title":"Deep sequencing for de novo construction of a marine fish (Sparus aurata) transcriptome database with a large coverage of protein-coding transcripts.","volume":"14","author":"Calduch-Giner","year":"2014","journal-title":"BMC Genom"},{"key":"B10","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1038\/nature06006","article-title":"The JAZ family of repressors is the missing link in jasmonate signalling.","volume":"448","author":"Chini","year":"2007","journal-title":"Nature"},{"key":"B11","article-title":"Advances in the interaction of plant pathogenic effector proteins and Jasmonin signaling pathways.","volume":"52","author":"Ding","year":"2016","journal-title":"Plant Physiol. J."},{"key":"B12","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1126\/science.1203877","article-title":"Evidence for network evolution in an Arabidopsis interactome map.","volume":"29","author":"Dreze","year":"2011","journal-title":"Science"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0066056","article-title":"Over expression of Vr UBC1, a mung mean E2 ubiquitin-conjugating enzyme, enhances osmotic stress tolerance in Arabidopsis.","volume":"8","author":"Eunsook","year":"2013","journal-title":"PLoS One"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2017.01147","article-title":"Crop production under drought and heat stress: plant responses and management options.","volume":"8","author":"Fahad","year":"2017","journal-title":"Front. Plant Sci."},{"key":"B15","first-page":"1433","article-title":"Effect of salicylic acid on physiological and biochemical characterization of maize grown in saline area.","volume":"44","author":"Fahad","year":"2012","journal-title":"Pak J. Bot."},{"key":"B16","first-page":"1635","article-title":"Ultraviolet radiation effect on photosynthetic pigments, biochemical attributes, antioxidant enzyme activity and hormonal contents of wheat.","volume":"11","author":"Fahad","year":"2013","journal-title":"J. Food Agri. Environ."},{"key":"B17","doi-asserted-by":"publisher","first-page":"4907","DOI":"10.1007\/s11356-0143754-2","article-title":"Potential role of phytohormones and plant growth-promoting rhizobacteria in abiotic stresses: consequences for changing environment.","volume":"22","author":"Fahad","year":"","journal-title":"Environ. Sci. Pollut. Res."},{"key":"B18","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1007\/s10725-014-0013-y","article-title":"Phytohormones and plant responses to salinity stress: a review.","volume":"75","author":"Fahad","year":"","journal-title":"Plant Growth Regul."},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0159590","article-title":"Responses of rapid viscoanalyzer profile and other rice grain qualities to exogenously applied plant growth regulators under high day and high night temperatures.","volume":"11","author":"Fahad","year":"","journal-title":"PLoS One"},{"key":"B20","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1111\/jac.12148","article-title":"Exogenously applied plant growth regulators affect heat-stressed rice pollens.","volume":"202","author":"Fahad","year":"","journal-title":"J. Agron. Crop Sci."},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2016.01250","article-title":"Exogenously applied plant growth regulators enhance the morphophysiological growth and yield of rice under high temperature.","volume":"7","author":"Fahad","year":"","journal-title":"Front. Plant Sci."},{"key":"B22","doi-asserted-by":"publisher","first-page":"191","DOI":"10.10106\/j.plaphy.2016.03.001","article-title":"A combined application of biochar and phosphorus alleviates heat-induced adversities on physiological, agronomical and quality attributes of rice.","volume":"103","author":"Fahad","year":"","journal-title":"Plant Physiol. Biochem."},{"key":"B23","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1016\/j.plaphy.2015.08.009","article-title":"A biochar application protects rice pollen from high-temperature stress.","volume":"96","author":"Fahad","year":"","journal-title":"Plant Physiol. Biochem."},{"key":"B24","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1007\/978-3-319-09132-7_10","article-title":"Crop plant hormones and environmental stress.","volume":"15","author":"Fahad","year":"","journal-title":"Sustain. Agric. Rev."},{"key":"B25","doi-asserted-by":"publisher","first-page":"1473","DOI":"10.1080\/03650340.2018.1443213","article-title":"Consequences of high temperature under changing climate optima for rice pollen characteristics-concepts and perspectives.","volume":"64","author":"Fahad","year":"2018","journal-title":"Arch. Agron. Soil Sci."},{"key":"B26","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1038\/340245a0","article-title":"A novel genetic system to detect protein-protein interactions.","volume":"340","author":"Fields","year":"1989","journal-title":"Nature"},{"key":"B27","doi-asserted-by":"publisher","first-page":"592","DOI":"10.15889\/j.issn.1002-1302.2020.12.004","article-title":"Ethylene signal transduction and its role in plant stress response.","volume":"48","author":"Gao","year":"2020","journal-title":"Jiangsu Agric. Sci."},{"key":"B28","doi-asserted-by":"publisher","first-page":"11872","DOI":"10.1073\/pnas.1205415109","article-title":"The genome of melon (Cucumis melo L.).","volume":"109","author":"Garcia-Mas","year":"2012","journal-title":"PNAS"},{"key":"B29","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.plaphy.2011.12.005","article-title":"Salicylic acid is a modulator of catalase isozymes in chickpea plants infected with fusarium oxysporum f. sp.","volume":"52","author":"Gayatridevi","year":"2012","journal-title":"Cicero. Plant Physiol. Biochem."},{"key":"B30","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1146\/annurev.phyto.35.1.111","article-title":"The evolutionary biology of fusarium oxysporum.","volume":"35","author":"Gordon","year":"1997","journal-title":"Annu. Rev. Phytopathol."},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.3390\/genes12081222","article-title":"Genetic resources and vulnerabilities of major cucurbit crops.","volume":"12","author":"Grumet","year":"2021","journal-title":"Genes"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.7666\/d.Y3271854","author":"Guo","year":"2017","journal-title":"Transcriptome Analysis and Mapping of Resistance Genes to Verticillium wilt Infection in Sunflower"},{"key":"B33","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1007\/s12600-013-0321-1","article-title":"Physiological races of fusarium oxysporum f.sp. melonis in Tunisia.","volume":"41","author":"Hela","year":"2013","journal-title":"Phytoparasitica"},{"key":"B34","doi-asserted-by":"publisher","first-page":"1180","DOI":"10.1094\/PDIS-91-9-1180","article-title":"Characterization and inheritance of a new source of resistance to fusarium oxysporum f. sp. melonis race 1.2 in cucumis melo.","volume":"91","author":"Herman","year":"2007","journal-title":"Plant Dis."},{"key":"B35","doi-asserted-by":"publisher","first-page":"560","DOI":"10.3724\/SP.J.1005.2012.00560","article-title":"PYR\/PYL\/RCAR proteins mediate signal transduction in plants.","volume":"34","author":"Hu","year":"2012","journal-title":"Genetics"},{"key":"B36","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.fsi.2018.08.002","article-title":"Transcriptomic responses to heat stress in rainbow trout Oncorhynchus mykiss head kidney head kidney.","volume":"82","author":"Huang","year":"2018","journal-title":"Fish Shellfish Immunol."},{"key":"B37","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1111\/j.1365-313X.2004.02134.x","article-title":"The fusarium wilt resistance locus fom-2 of melon contains a single resistance gene with complex features.","volume":"39","author":"Joobeur","year":"2004","journal-title":"Plant J."},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0143488","article-title":"Genome-wide identification, phylogenetic and expression analyses of the ubiquitin-conjugating enzyme gene family in maize.","volume":"10","author":"Jue","year":"2015","journal-title":"PLoS One"},{"key":"B39","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1104\/pp.107.110981","article-title":"Overexpression of AtMYB44 enhances stomatal closure to confer abiotic stress tolerance in transgenic Arabidopsis.","volume":"146","author":"Jung","year":"2008","journal-title":"Plant Physiol."},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1186\/1755-8794-7-57","article-title":"Identification of co-expression gene networks, regulatory genes and pathways for obesity based on adipose tissue RNA sequencing in a porcine model.","volume":"7","author":"Kogelman","year":"2014","journal-title":"BMC Med. Genom."},{"key":"B41","doi-asserted-by":"publisher","first-page":"1597","DOI":"10.1104\/pp.105.067983","article-title":"Genome analysis and functional characterization of the e2 and ring-type e3 ligase ubiquitination enzymes of Arabidopsis.","volume":"139","author":"Kraft","year":"2005","journal-title":"Plant Physiol."},{"key":"B42","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1007\/BF02979687","article-title":"Physiologic races of fusarium oxysporum f. sp. melonis in thesoutheastern anatolia region of turkey and varietal reactions to races of the pathogen.","volume":"30","author":"Kurt","year":"2002","journal-title":"Phytoparasitica"},{"key":"B43","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1038\/nmeth.1923","article-title":"Fast gapped-read alignment with bowtie 2.","volume":"9","author":"Langmead","year":"2012","journal-title":"Nat. Methods"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1186\/s12864-015-2318-2","article-title":"Transcriptome profiling of soybean (glycine max) roots challenged with pathogenic and non-pathogenic isolates of Fusarium oxysporum.","volume":"16","author":"Lanubile","year":"2015","journal-title":"BMC Genom."},{"key":"B45","doi-asserted-by":"publisher","first-page":"2153","DOI":"10.3864\/j.issn.0578-1752.2016.11.011","article-title":"Effects of fusarium oxysporum f. sp. melonis on lignin, activities of lingin-related enzymes and genes expressions of CmCADs in oriental melon (Cucumis melo var. makuwa makino).","volume":"49","author":"Liu","year":"2016","journal-title":"Sci. Agric. Sin."},{"key":"B46","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1007\/s11103-020-01018-7","article-title":"Lignin synthesized by CmCAD2 and CmCAD3 in oriental melon (Cucumis melo L.) seedlings contributes to drought tolerance.","volume":"103","author":"Liu","year":"2020","journal-title":"Plant Mol. Biol."},{"key":"B47","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12864-016-2780-5","article-title":"Transcriptome analysis of maize resistance to fusarium graminearum.","volume":"17","author":"Liu","year":"2016","journal-title":"BMC Genom."},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0037209","article-title":"Transcriptomic characterization of temperature stress responses in larval zebrafish.","volume":"7","author":"Long","year":"2012","journal-title":"PLoS One"},{"key":"B49","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1111\/j.1364-3703.2006.00365.x","article-title":"Trifluralin herbicide-induced resistance of melon to fusarium wilt involves expression of stress and defence-related genes.","volume":"8","author":"Lotan-Pompan","year":"2007","journal-title":"Mol. Plant Pathol."},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-Seq data with DESeq2.","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol."},{"key":"B51","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1111\/j.1438-8677.2012.00675.x","article-title":"AtMYB44 regulates resistance to the green peach aphid and diamondback moth by activating EIN2-affected defences in Arabidopsis.","volume":"15","author":"L\u00fc","year":"2013","journal-title":"Plant Biol. Stuttg."},{"key":"B52","first-page":"17","article-title":"Construction of a three-frame yeast two-hybrid cDNA library of Fusarium oxysporum.","volume":"26","author":"Luan","year":"2019","journal-title":"J. Northeast Agric. Univ."},{"key":"B53","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.gene.2014.04.032","article-title":"Generation and characterization of the sea bass dicentrarchus labrax brain and liver transcriptomes.","volume":"544","author":"Magnanou","year":"2014","journal-title":"Gene"},{"key":"B54","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1016\/j.pbi.2005.05.015","article-title":"The role of abscisic acid in plant-pathogen interactions.","volume":"8","author":"Mauch-Mani","year":"2005","journal-title":"Curr. Opin. Plant Biol."},{"key":"B55","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1007\/BF02772762","article-title":"Identification of a novel rice bZIP-type transcription factor gene, OsbZIP1, involved in response to infection of magnaporthe grisea.","volume":"23","author":"Meng","year":"2005","journal-title":"Plant Mol. Biol. Rep."},{"key":"B56","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1007\/s00239-009-9225-6","article-title":"What was the set of ubiquitin and ubiquitin-like conjugating enzymes in the eukaryote common ancestor?","volume":"68","author":"Michelle","year":"2009","journal-title":"J. Mol. Evol."},{"key":"B57","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1023\/A:1020674929084","article-title":"Production of beauvericin by different races of Fusarium oxysporum f. sp. melonis, the fusarium wilt agent of muskmelon.","volume":"10","author":"Moretti","year":"2002","journal-title":"Eur. J. Plant Pathol."},{"key":"B58","doi-asserted-by":"publisher","first-page":"804","DOI":"10.1094\/PHYTO.1998.88.8.804","article-title":"Pathogenic and genetic variation in the Japanese strains of fusarium oxysporum f. sp. melonis.","volume":"88","author":"Namiki","year":"","journal-title":"Phytopathology"},{"key":"B59","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1007\/PL00012915","article-title":"Occurrence of Fusarium oxysporum f. sp. melonis race 1 in Japan.","volume":"66","author":"Namiki","year":"","journal-title":"J. Gen. Plant Pathol."},{"key":"B60","doi-asserted-by":"publisher","first-page":"1958","DOI":"10.16420\/j.issn.0513-353x.2012.10.001","article-title":"Construction of cDNA expression library of watermelon and screening and identification of interaction partner of FonSIX6, a virulence factor from Fusarium oxysporum f. sp.","volume":"10","author":"Niu","year":"2016","journal-title":"Niveurn. Acta Hortic. Sin."},{"key":"B61","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1093\/jxb\/54.381.291","article-title":"Early steps in the oxidative burst induced cadmium in cultured tobacco cells (BY-2 line).","volume":"54","author":"Olmos","year":"2003","journal-title":"J. Exp. Bot."},{"key":"B62","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1007\/s10681-010-0201-4","article-title":"Inheritance of resistance to Fusarium oxysporum f. sp. melonis races 0 and 2 in melon accession tortuga.","volume":"176","author":"Oumouloud","year":"2010","journal-title":"Euphytica"},{"key":"B63","doi-asserted-by":"publisher","first-page":"3193","DOI":"10.1046\/j.1432-1033.2002.02994.x","article-title":"A Ca2+\/Ca M-dependent kinase from pea is stress regulated and in vitro phosphorylates a protein that binds to At Ca M5 promoter.","volume":"269","author":"Pandey","year":"2002","journal-title":"Eur. J. Chem."},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V124.21.2445.3445","article-title":"Weighted gene co-expression network analysis (WGCNA) identifies highly proliferative myeloma sub-group responsive to CDK4\/ARK5 inhibition.","volume":"124","author":"Perumal","year":"2014","journal-title":"Blood"},{"key":"B65","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1038\/nchembio.164","article-title":"Networking by small-molecule hormones in plant immunity.","volume":"5","author":"Pieterse","year":"2009","journal-title":"Nat. Chem. Biol."},{"key":"B66","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/j.margen.2015.12.001","article-title":"Liver transcriptome sequencing and de novo annotation of the large yellow croaker (Larimichthy crocea) under heat and cold stress.","volume":"25","author":"Qian","year":"2016","journal-title":"Mar. Genom."},{"key":"B67","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1089\/omi.2013.0110","article-title":"RNA-seq technology and its application in fish transcriptomics.","volume":"18","author":"Qian","year":"2014","journal-title":"OMICS"},{"key":"B68","doi-asserted-by":"publisher","first-page":"1105","DOI":"10.1094\/Phyto-66-1105","article-title":"A proposed nomenclature of Fusarium oxysporum f. sp. melonis races and resistance genes in cucumis melo.","volume":"73","author":"Risser","year":"1976","journal-title":"Phytopathology"},{"key":"B69","doi-asserted-by":"publisher","DOI":"10.1186\/1752-0509-4-8","article-title":"A general co-expression network-based approach to gene expression analysis: comparison and applications.","volume":"4","author":"Ruan","year":"2010","journal-title":"BMC Syst. Biol."},{"key":"B70","doi-asserted-by":"publisher","first-page":"37121","DOI":"10.1007\/s11356-020-09764-3","article-title":"Foliar application of gibberellic acid endorsed phytoextraction of copper and alleviates oxidative stress in jute (Corchorus capsularis L.) plant grown in highly copper-contaminated soil of China.","volume":"27","author":"Saleem","year":"","journal-title":"Environ. Sci. Pollution Res."},{"key":"B71","doi-asserted-by":"publisher","first-page":"836","DOI":"10.32615\/ps.2020.010","article-title":"Leaf gas exchange, oxidative stress, and physiological attributes of rapeseed (Brassica napus L.) grown under different light-emitting diodes.","volume":"58","author":"Saleem","year":"","journal-title":"Photosynthetica"},{"key":"B72","doi-asserted-by":"publisher","first-page":"5211","DOI":"10.1007\/s11356-019-07264-7","article-title":"Copper-induced oxidative stress, initiation of antioxidants and phytoremediation potential of flax (Linum usitatissimum L.) seedlings grown under the mixing of two different soils of China.","volume":"27","author":"Saleem","year":"","journal-title":"Environ. Sci. Poll. Res."},{"key":"B73","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1186\/1471-2164-11-564","article-title":"Characterization of the rainbow trout transcriptome using sanger and 454 pyrosequencing approaches.","volume":"11","author":"Salem","year":"2016","journal-title":"BMC Genom."},{"key":"B74","doi-asserted-by":"publisher","first-page":"17647","DOI":"10.1007\/s11356-016-6957-x","article-title":"Silicate application increases the photosynthesis and its associated metabolic activities in kentucky bluegrass under drought stress and post-drought recovery.","volume":"23","author":"Saud","year":"2016","journal-title":"Environ. Sci. Pollut. Res."},{"key":"B75","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-020-63548-w","article-title":"Determining nitrogen isotopes discrimination under drought stress on enzymatic activities, nitrogen isotope abundance and water contents of kentucky bluegrass.","volume":"10","author":"Saud","year":"2020","journal-title":"Sci. Rep."},{"key":"B76","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2017.00983","article-title":"Effects of nitrogen supply on water stress and recovery mechanisms in kentucky bluegrass plants.","volume":"8","author":"Saud","year":"2017","journal-title":"Front. Plant Sci."},{"key":"B77","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2014\/368694","article-title":"Silicon application increases drought tolerance of kentucky bluegrass by improving plant water relations and morph physiological functions.","volume":"2014","author":"Saud","year":"2014","journal-title":"Sci. World. J."},{"key":"B78","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1111\/nph.13584","article-title":"Comparative genomics of Fusarium oxysporum f. sp. melonis reveals the secreted protein recognized by the Fom-2 resistance gene in melon.","volume":"1","author":"Schmidt","year":"2016","journal-title":"New Phytol."},{"key":"B79","doi-asserted-by":"publisher","first-page":"1101","DOI":"10.1038\/nprot.2008.73","article-title":"Analyzing real-time PCR data by the comparative CT method.","volume":"3","author":"Schmittgen","year":"2008","journal-title":"Nat. Protoc."},{"key":"B80","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2017.00362","article-title":"Transcriptome analysis of the melon-Fusarium oxysporum f. sp. melonis race 1.2 pathosystem in susceptible and resistant plants.","volume":"8","author":"Sebastiani","year":"2017","journal-title":"Front. Plant. Sci."},{"key":"B81","article-title":"Construction and analysis of hami melon transcriptomes before and after Penicillium infection.","volume":"35","author":"Shan","year":"2016","journal-title":"J. Food Biotech."},{"key":"B82","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2022.905181","article-title":"GhHAI2, GhAHG3, and GhABI2 negatively regulate osmotic stress tolerance via ABA-dependent pathway in cotton (Gossypium hirsutum L.).","volume":"13","author":"Shazadee","year":"2022","journal-title":"Front. Plant Sci."},{"key":"B83","author":"Su","year":"2014","journal-title":"Transcriptomics and Proteomics of Sugarcane Response to Sporisorium scitamineum Infection and Mining of Resistance-Related Genes."},{"key":"B84","article-title":"Transcriptome analysis of incompatible interactions between watermelon and Fusarium oxysporum.","volume":"32","author":"Sun","year":"2019","journal-title":"China Melon Vegetables"},{"key":"B85","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2020.00831","article-title":"Linkage mapping and comparative transcriptome analysis of firmness in watermelon (Citrullus lanatus).","volume":"11","author":"Sun","year":"2020","journal-title":"Front. Plant Sci."},{"key":"B86","article-title":"Fusarium wilt infection in melon: a transcriptomic approach to characterize the genetic dialogue between host and pathogen","author":"Szafranska","year":"2008","journal-title":"Proceedings of the IXth EUCARPIA Meeting On Genetics And Breeding Of Cucurbitaceae"},{"key":"B87","first-page":"645","article-title":"Acquired resistance in Arabidopsis.","volume":"4","author":"Uknes","year":"1992","journal-title":"Plant Cell"},{"key":"B88","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00344-021-10493-1","article-title":"Linking plants functioning to adaptive responses under heat stress conditions: a mechanistic review","author":"Ul Hassan","year":"2021","journal-title":"J. Plant Growth Regul."},{"key":"B89","first-page":"482","article-title":"Screening of putative proteins that are interacted with NBS-LRR protein pik-h by the yeast two-hybrid system.","volume":"3","author":"Wang","year":"2016","journal-title":"Sci. Agric. Sin."},{"key":"B90","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1007\/s10142-018-0595-y","article-title":"Transcriptomics analysis revealing candidate networks and genes for the body size sexual dimorphism of Chinese tongue sole (Cynoglossus semilaevis).","volume":"18","author":"Wang","year":"2018","journal-title":"Funct. Integr.Genom."},{"key":"B91","first-page":"1","article-title":"Yeast two-hybrid system was used to screen GbVWR interacting proteins.","volume":"5","author":"Wang","year":"2018","journal-title":"J. Agric. Univ. Hebei"},{"key":"B92","doi-asserted-by":"publisher","DOI":"10.1186\/PREACCEPT-3895766441330481","article-title":"Tomato nuclear proteome reveals the involvement of specific e2 ubiquitin-conjugating enzymes in fruit ripening.","volume":"15","author":"Wang","year":"2014","journal-title":"Genome Biol."},{"key":"B93","doi-asserted-by":"publisher","first-page":"1039","DOI":"10.1016\/j.jplph.2013.02.011","article-title":"Systemic acquired resistance in cavendish banana induced by infection with an incompatible strain of Fusarium oxysporum f. sp. cubense.","volume":"170","author":"Wu","year":"2013","journal-title":"J. Plant Physiol."},{"key":"B94","doi-asserted-by":"publisher","first-page":"W316","DOI":"10.1093\/nar\/gkr483","article-title":"KOBAS 2.0: a web server for annotation and identification of enriched pathways and diseases.","volume":"39","author":"Xie","year":"2011","journal-title":"Nucleic Acids Res."},{"key":"B95","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2018.0308","article-title":"A nucleotide-binding site-leucine-rich repeat receptor pair confers broad-spectrum disease resistance through physical association in rice.","volume":"374","author":"Xie","year":"2019","journal-title":"Philos. Trans. R. Soc. London Seri. B Biol. Sci."},{"key":"B96","doi-asserted-by":"publisher","first-page":"1102","DOI":"10.1111\/tpj.15371","article-title":"The Scarecrow-like transcription factor SlSCL3 regulates volatile terpene biosynthesis and glandular trichome size in tomato (Solanum lycopersicum).","volume":"107","author":"Yang","year":"2021","journal-title":"Plant J."},{"key":"B97","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23020642","article-title":"Genome-wide analysis of the peroxidase gene family and verification of lignin synthesis-related genes in watermelon.","volume":"23","author":"Yang","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"B98","doi-asserted-by":"publisher","first-page":"11","DOI":"10.13560\/j.cnki.biotech.bull.1985.2016.10.007","article-title":"Ethylene signaling and its role in plant stress response.","volume":"32","author":"Zhang","year":"2016","journal-title":"Biotechnol. Bull."},{"key":"B99","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0122621","article-title":"Characterization of the ubiquitin-conjugating enzyme gene family in rice and evaluation of expression profiles under abiotic stresses and hormone treatments.","volume":"10","author":"Zhang","year":"2015","journal-title":"PLoS One"},{"key":"B100","doi-asserted-by":"publisher","first-page":"60","DOI":"10.16420\/j.issn.0513-353x.2011.12.014","article-title":"Cloning and expression analysis of bcubce2 gene in Chinese cabbage.","volume":"34","author":"Zhao","year":"2014","journal-title":"Acta Bot. Boreal. Occid. Sin."},{"key":"B101","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-08763-3","article-title":"Comparative transcriptome analysis of melon (Cucumis melo L.) reveals candidate genes and pathways involved in powdery resistance.","volume":"2022","author":"Zhao","year":"2022","journal-title":"Sci. Rep."},{"key":"B102","doi-asserted-by":"publisher","DOI":"10.1007\/s11103-009-9575-x","article-title":"Overexpression of soybean ubiquitin-conjugating enzyme gene gmubc2 confers enhanced drought and salt tolerance through modulating abiotic stress-responsive gene expression in Arabidopsis.","volume":"72","author":"Zhou","year":"2010","journal-title":"Plant Mol. Biol."},{"key":"B103","doi-asserted-by":"publisher","DOI":"10.1186\/s12864-016-3442-3","article-title":"Comparative transcriptome analysis of two contrasting watermelon genotypes during fruit development and ripening.","volume":"18","author":"Zhu","year":"2017","journal-title":"BMC Genom."},{"key":"B104","doi-asserted-by":"crossref","first-page":"600","DOI":"10.21273\/JASHS.110.5.600","article-title":"Inheritance of resistance in muskmelon to fusarium wilt.","volume":"110","author":"Zink","year":"1985","journal-title":"J. Amer. Soc. Hortic. Sci."},{"key":"B105","doi-asserted-by":"publisher","DOI":"10.7666\/d.Y2528585","author":"Zou","year":"2013","journal-title":"Study on the Function of Chromatin Modified Genes HUB1 and CHR5 and Transcription Factor MYB44 in Arabidopsis thaliana Defense Response. Doctoral thesis"}],"container-title":["Frontiers in Plant Science"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpls.2022.961586\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,12]],"date-time":"2023-02-12T10:49:38Z","timestamp":1676198978000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpls.2022.961586\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,22]]},"references-count":105,"alternative-id":["10.3389\/fpls.2022.961586"],"URL":"https:\/\/doi.org\/10.3389\/fpls.2022.961586","relation":{},"ISSN":["1664-462X"],"issn-type":[{"value":"1664-462X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,22]]},"article-number":"961586"}}