{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T17:43:33Z","timestamp":1790876613302,"version":"4.1.0"},"reference-count":74,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T00:00:00Z","timestamp":1774396800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Plant Sci."],"abstract":"<jats:p>\n                    Among citrus diseases, Huanglongbing (HLB) is recognized as the most destructive and economically damaging worldwide. It is mainly associated with \u2018\n                    <jats:italic>Candidatus<\/jats:italic>\n                    Liberibacter asiaticus\u2019 (\n                    <jats:italic>C<\/jats:italic>\n                    Las) being transmitted by\n                    <jats:italic>Diaphorina citri<\/jats:italic>\n                    . There are no curative treatments or commercial citrus varieties resistant to\n                    <jats:italic>C<\/jats:italic>\n                    Las. Wild Aurantioideae species have been widely screened and, recently, Oceanian genotypes graft- and sexually compatible with\n                    <jats:italic>Citrus<\/jats:italic>\n                    were identified as HLB-resistant; however, there is no information regarding their use as interstocks of commercial varieties yet. Under greenhouse conditions, six HLB-resistant genotypes were evaluated as interstocks between \u2018Valencia\u2019 sweet orange scion and \u2018Rangpur\u2019 lime rootstock, both susceptible to HLB, with \u2018Valencia\u2019 interstock as the control. Rootstocks were nucellar seedlings, and the scion was a commercial accession preimmunized with a mild CTV strain. Plants were assessed for\n                    <jats:italic>C<\/jats:italic>\n                    Las infection and titer in leaves, stem bark, and roots up to 12\u201324 months after graft-inoculation in the scion and compared to non-inoculated controls. Furthermore, molecular, anatomical, and biometric variables were investigated. As expected, the scion variety was colonized by\n                    <jats:italic>C<\/jats:italic>\n                    Las regardless of the genotype evaluated as interstock. Although bacteria were detected in the roots of most\n                    <jats:italic>C<\/jats:italic>\n                    Las-inoculated plants,\n                    <jats:italic>C<\/jats:italic>\n                    Las movement from the scion to the roots was blocked in 42% and 86% of composite plants when using a F1 hybrid of\n                    <jats:italic>C.\u00a0australis<\/jats:italic>\n                    \u00d7\n                    <jats:italic>C. inodora<\/jats:italic>\n                    or an admixture hybrid of\n                    <jats:italic>C. glauca<\/jats:italic>\n                    ,\n                    <jats:italic>C. australis<\/jats:italic>\n                    , and\n                    <jats:italic>C.\u00a0australasica<\/jats:italic>\n                    as interstocks. Overall,\n                    <jats:italic>C<\/jats:italic>\n                    Las titers were similar in infected plant tissues among the evaluated genotypes, but titers were lower in interstock bark tissues compared to scion and rootstock ones. After one-two years of\n                    <jats:italic>C<\/jats:italic>\n                    Las + CTV infection (experiments I and II, respectively), the dry weight of the root system decreased by 50% in infected trees compared to control trees for most genotypes, and\n                    <jats:italic>C<\/jats:italic>\n                    Las + CTV infection was associated with changes in the sieve phloem and gene expression. These findings suggest that, despite CTV infection, interstocks derived from some hybrids of Australian citrus types have the potential to restrict the movement of\n                    <jats:italic>C<\/jats:italic>\n                    Las from the scion into the roots of infected citrus trees. Long-term evaluation of composite plants in field conditions is necessary to assess tree performance and, ultimately, the impact of\n                    <jats:italic>C<\/jats:italic>\n                    Las blockage by interstocking on HLB disease damage.\n                  <\/jats:p>","DOI":"10.3389\/fpls.2026.1733981","type":"journal-article","created":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T06:49:47Z","timestamp":1774421387000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Can an HLB-resistant interstock block the long-distance movement of \u2018Candidatus Liberibacter asiaticus\u2019 within citrus trees?"],"prefix":"10.3389","volume":"17","author":[{"given":"Josiane C.","family":"Darolt","sequence":"first","affiliation":[{"name":"Fund for Citrus Protection","place":["Araraquara, S\u00e3o Paulo, Brazil"]},{"name":"Embrapa Cassava and Fruits","place":["Cruz das Almas, Bahia, Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laudecir L.","family":"Raiol-Junior","sequence":"additional","affiliation":[{"name":"Fund for Citrus Protection","place":["Araraquara, S\u00e3o Paulo, Brazil"]},{"name":"Embrapa Cassava and Fruits","place":["Cruz das Almas, Bahia, Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Everton V.","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Fund for Citrus Protection","place":["Araraquara, S\u00e3o Paulo, Brazil"]},{"name":"Embrapa Cassava and Fruits","place":["Cruz das Almas, Bahia, Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00f4nica N.","family":"Alves","sequence":"additional","affiliation":[{"name":"Fund for Citrus Protection","place":["Araraquara, S\u00e3o Paulo, Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nelson A.","family":"Wulff","sequence":"additional","affiliation":[{"name":"Fund for Citrus Protection","place":["Araraquara, S\u00e3o Paulo, Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9mima","family":"Bag\u00e9a","sequence":"additional","affiliation":[{"name":"Unit\u00e9 Mixte de Recherche Am\u00e9lioration G\u00e9n\u00e9tique et Adaptation des Plantes M\u00e9diterran\u00e9ennes et Tropicales (UMR AGAP) Institut, Univ. Montpellier, Centre de coop\u00e9ration International en Recherche Agronomique pour le D\u00e9veloppement (CIRAD), Institut National de Recherche pour l\u2019Agriculture, l\u2019Alimentation et l\u2019Environnement (INRAE)","place":["Institut Agro, Montpellier, France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Gros","sequence":"additional","affiliation":[{"name":"Institut de Syst\u00e9matique, Evolution, Biodiversit\u00e9 (ISYEB), Mus\u00e9um National d\u2019Histoire Naturelle, CNRS, Sorbonne Universit\u00e9, EPHE, Universit\u00e9 des Antilles","place":["Pointe-\u00e0-Pitre, France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e1rbara","family":"Hufnagel","sequence":"additional","affiliation":[{"name":"Unit\u00e9 Mixte de Recherche Am\u00e9lioration G\u00e9n\u00e9tique et Adaptation des Plantes M\u00e9diterran\u00e9ennes et Tropicales (UMR AGAP) Institut, Univ. Montpellier, Centre de coop\u00e9ration International en Recherche Agronomique pour le D\u00e9veloppement (CIRAD), Institut National de Recherche pour l\u2019Agriculture, l\u2019Alimentation et l\u2019Environnement (INRAE)","place":["Institut Agro, Montpellier, France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raphael","family":"Morillon","sequence":"additional","affiliation":[{"name":"Unit\u00e9 Mixte de Recherche Am\u00e9lioration G\u00e9n\u00e9tique et Adaptation des Plantes M\u00e9diterran\u00e9ennes et Tropicales (UMR AGAP) Institut, Univ. Montpellier, Centre de coop\u00e9ration International en Recherche Agronomique pour le D\u00e9veloppement (CIRAD), Institut National de Recherche pour l\u2019Agriculture, l\u2019Alimentation et l\u2019Environnement (INRAE)","place":["Institut Agro, Montpellier, France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leandro","family":"Pe\u00f1a","sequence":"additional","affiliation":[{"name":"Fund for Citrus Protection","place":["Araraquara, S\u00e3o Paulo, Brazil"]},{"name":"Instituto de Biolog\u00eda Molecular y Celular de Plantas (IBMCP), Consejo Superior de Investigaciones Cient\u00edficas (CSIC) Polytechnic University of Valencia (UPV)","place":["Valencia, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo A.","family":"Girardi","sequence":"additional","affiliation":[{"name":"Fund for Citrus Protection","place":["Araraquara, S\u00e3o Paulo, Brazil"]},{"name":"Embrapa Cassava and Fruits","place":["Cruz das Almas, Bahia, Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,3,25]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"882","DOI":"10.1104\/pp.19.01391","article-title":"Dynamics of candidatus liberibacter asiaticus movement and sieve-pore plugging in citrus sink cells","volume":"182","author":"Achor","year":"2020","journal-title":"Plant Physiol."},{"key":"B2","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1071\/BT99042","article-title":"Horticultural development of Australian native edible plants","volume":"48","author":"Ahmed","year":"2000","journal-title":"Aust. 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