{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T05:00:13Z","timestamp":1781067613546,"version":"3.54.1"},"reference-count":103,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T00:00:00Z","timestamp":1781049600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008363","name":"Sichuan Agricultural University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008363","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Plant Sci."],"abstract":"<jats:p>\n                    ABSCISIC ACID INSENSITIVE 5 (ABI5) is a key regulator that represses seed germination, flowering, and seedling growth in\n                    <jats:italic>Arabidopsis thaliana<\/jats:italic>\n                    and functions in abscisic acid (ABA) signal transduction. However, whether ABI5 is involved in other biological processes and its interacting partners remain largely unknown. Here, we show that\n                    <jats:italic>BnaABI5<\/jats:italic>\n                    , an ortholog of\n                    <jats:italic>AtABI5<\/jats:italic>\n                    , positively regulates erucic acid synthesis and the transcript level of the marker gene\n                    <jats:italic>FAE1<\/jats:italic>\n                    in\n                    <jats:italic>Brassica napus<\/jats:italic>\n                    . Expression patterns of\n                    <jats:italic>BnaABI5<\/jats:italic>\n                    and\n                    <jats:italic>BnaFAE1<\/jats:italic>\n                    overlap during specific stages of seed development, as indicated by the BnIR database, and GUS staining assays show that both genes are expressed in seeds. BnaABI5 is a bZIP transcription factor that localizes to the nucleus and activates transcription of the reporter gene\n                    <jats:italic>LacZ<\/jats:italic>\n                    . We further demonstrate that the mediator subunit BnaMED25 is involved in modulating erucic acid synthesis through interaction with BnaABI5\n                    <jats:italic>in vivo<\/jats:italic>\n                    and\n                    <jats:italic>in vitro<\/jats:italic>\n                    . Dual-luciferase assays and electrophoretic mobility shift assays (EMSAs) indicate that BnaMED25 facilitates BnaABI5-mediated regulation of\n                    <jats:italic>BnaFAE1<\/jats:italic>\n                    expression. Genetic experiments indicate that, compared with wild-type Col-0 and the variety \u201cWangxiangyou1881\u201d, the transcript level of the marker gene\n                    <jats:italic>FAE1<\/jats:italic>\n                    is increased in\n                    <jats:italic>BnaABI5<\/jats:italic>\n                    -overexpressing\n                    <jats:italic>Arabidopsis<\/jats:italic>\n                    and oilseed rape, respectively. Erucic acid content in the tested seeds exhibited a corresponding trend. Taken together, these results demonstrate that BnaMED25 is involved in BnaABI5-mediated regulation of erucic acid accumulation and reveal a mechanism by which ABI5 and its recruiting factor play a significant role in long-chain fatty acid synthesis.\n                  <\/jats:p>","DOI":"10.3389\/fpls.2026.1798651","type":"journal-article","created":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T04:29:50Z","timestamp":1781065790000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Mediator subunit MED25 represses ABI5-dependent activation of erucic acid biosynthetic gene FAE1 in Brassica napus"],"prefix":"10.3389","volume":"17","author":[{"given":"Zhuang","family":"Li","sequence":"first","affiliation":[{"name":"State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University","place":["Chengdu, China"]},{"name":"College of Agronomy, Sichuan Agricultural University","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shouchuan","family":"Zhi","sequence":"additional","affiliation":[{"name":"College of Agronomy, Sichuan Agricultural University","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongkang","family":"Tang","sequence":"additional","affiliation":[{"name":"College of Agronomy, Sichuan Agricultural University","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huan","family":"Li","sequence":"additional","affiliation":[{"name":"College of Agronomy, Sichuan Agricultural University","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengliang","family":"Tian","sequence":"additional","affiliation":[{"name":"College of Agronomy, Sichuan Agricultural University","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaobin","family":"Pu","sequence":"additional","affiliation":[{"name":"Crop Research Institute of Sichuan Academy of Agricultural Sciences (Sichuan Germplasm Resources Center), Sichuan Academy of Agricultural Sciences","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongcheng","family":"Wu","sequence":"additional","affiliation":[{"name":"College of Agronomy, Sichuan Agricultural University","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,6,10]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25063308","article-title":"Morpho-physiochemical induces and transcriptome analysis reveal the role of glucosinolate and erucic acid in response to drought stress during seed germination of rapeseed","volume":"25","author":"Ai","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"B2","doi-asserted-by":"publisher","first-page":"1566","DOI":"10.1111\/tpj.15132","article-title":"MdABI5 works with its interaction partners to regulate abscisic acid-mediated leaf senescence in apple","volume":"105","author":"An","year":"2021","journal-title":"Plant J."},{"key":"B3","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1111\/nph.19548","article-title":"The expression of genes encoding novel Sesame oleosin variants facilitates enhanced triacylglycerol accumulation in Arabidopsis leaves and seeds","volume":"243","author":"Anaokar","year":"2024","journal-title":"New Phytol."},{"key":"B4","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1016\/j.molcel.2007.05.007","article-title":"Purification of a plant mediator from Arabidopsis thaliana identifies PFT1 as the Med25 subunit","volume":"26","author":"B\u00e4ckstr\u00f6m","year":"2007","journal-title":"Mol. Cell"},{"key":"B5","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1111\/j.1365-313X.2007.03092.x","article-title":"WRINKLED1 specifies the regulatory action of LEAFY COTYLEDON2 towards fatty acid metabolism during seed maturation in Arabidopsis","volume":"50","author":"Baud","year":"2007","journal-title":"Plant J."},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1000603","article-title":"Molecular architecture of the human Mediator\u2013RNA polymerase II\u2013TFIIF assembly","volume":"9","author":"Bernecky","year":"2011","journal-title":"PloS Biol."},{"key":"B7","doi-asserted-by":"publisher","first-page":"1533","DOI":"10.1104\/pp.005793","article-title":"Regulation and role of the Arabidopsis abscisic acid-insensitive 5 gene in abscisic acid, sugar, and stress response","volume":"129","author":"Brocard","year":"2002","journal-title":"Plant Physiol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"1262","DOI":"10.1104\/pp.17.00478","article-title":"OsbZIP48, a HY5 transcription factor ortholog, exerts pleiotropic effects in light-regulated development","volume":"176","author":"Burman","year":"2018","journal-title":"Plant Physiol."},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbi.2022.102191","article-title":"Better together: Protein partnerships forlineage-specific oil accumulation","volume":"66","author":"Busta","year":"2022","journal-title":"Curr. Opin. Plant Biol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"4220","DOI":"10.1105\/tpc.112.103028","article-title":"Non-Recognition-of-BTH4, an Arabidopsis mediator subunit homolog, is necessary for development and response to salicylic acid","volume":"24","author":"Canet","year":"2012","journal-title":"Plant Cell"},{"key":"B11","doi-asserted-by":"publisher","first-page":"881","DOI":"10.1038\/nature01636","article-title":"Regulation of flowering time by light quality","volume":"423","author":"Cerd\u00e1n","year":"2003","journal-title":"Nature"},{"key":"B12","doi-asserted-by":"publisher","first-page":"2898","DOI":"10.1105\/tpc.112.098277","article-title":"The Arabidopsis mediator subunit MED25 Differentially regulates jasmonate and abscisic acid signaling through interacting with the MYC2 and ABI5 transcription factors","volume":"24","author":"Chen","year":"2012","journal-title":"Plant Cell"},{"key":"B13","doi-asserted-by":"publisher","first-page":"1023","DOI":"10.1104\/pp.112.202945","article-title":"The effect of TRANSPARENT TESTA2 on seed fatty acid biosynthesis and tolerance to environmental stresses during young seedling establishment in Arabidopsis","volume":"160","author":"Chen","year":"2012","journal-title":"Plant Physiol."},{"key":"B14","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1104\/pp.15.00943","article-title":"TRANSPARENT TESTA GLABRA1 regulates the accumulation of Seed storage reserves in Arabidopsis","volume":"169","author":"Chen","year":"2015","journal-title":"Plant Physiol."},{"key":"B15","doi-asserted-by":"publisher","first-page":"1053","DOI":"10.1105\/tpc.113.121566","article-title":"Abscisic acid regulates early seed development in Arabidopsis by ABI5- mediated transcription of SHORT HYPOCOTYL UNDER BLUE1","volume":"26","author":"Cheng","year":"2014","journal-title":"Plant Cell"},{"key":"B16","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1046\/j.1365-313x.1998.00343.x","article-title":"Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana","volume":"16","author":"Clough","year":"1998","journal-title":"Plant J."},{"key":"B17","doi-asserted-by":"publisher","first-page":"1183","DOI":"10.1111\/tpj.15377","article-title":"Ferredoxin 1 is downregulated by the accumulation of abscisic acid in an ABI5-dependent manner to facilitate rice stripe virus infection in Nicotiana benthamiana and rice","volume":"107","author":"Cui","year":"2021","journal-title":"Plant J."},{"key":"B18","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1007\/s11032-020-01174-0","article-title":"An efficient Agrobacterium-mediated transformation method using hypocotyl as explants for Brassica napus","volume":"40","author":"Dai","year":"2020","journal-title":"Mol. Breed."},{"key":"B19","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1016\/S1097-2765(02)00598-1","article-title":"Structure of the yeast RNA polymerase II holoenzyme: Mediator conformation and polymerase interaction","volume":"10","author":"Davis","year":"2002","journal-title":"Mol. Cell"},{"key":"B20","doi-asserted-by":"publisher","first-page":"1038","DOI":"10.1093\/plcell\/koac349","article-title":"Tomato MED25 regulates fruit ripening by interacting with EIN3-like transcription factors","volume":"35","author":"Deng","year":"2023","journal-title":"Plant Cell"},{"key":"B21","doi-asserted-by":"publisher","first-page":"3269","DOI":"10.1105\/tpc.17.00282","article-title":"Mediator complex subunits MED2, MED5, MED16, and MED23 genetically interact in the regulation of phenylpropanoid biosynthesis","volume":"29","author":"Dolan","year":"2017","journal-title":"Plant Cell"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2017.00226","article-title":"MYB76 inhibits seed fatty acid accumulation in Arabidopsis","volume":"8","author":"Duan","year":"2017","journal-title":"Front. Plant Sci."},{"key":"B23","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1007\/s11103-005-8767-2","article-title":"Redundant and distinct functions of the ABA response loci ABA-INSENSITIVE(ABI)5 and ABRE-BINDING FACTOR (ABF)3","volume":"59","author":"Finkelstein","year":"2005","journal-title":"Plant Mol. Biol."},{"key":"B24","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1105\/tpc.12.4.599","article-title":"The Arabidopsis abscisic acid response gene ABI5 encodes a basic leucine zipper transcription factor","volume":"12","author":"Finkelstein","year":"2000","journal-title":"Plant Cell"},{"key":"B25","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1104\/pp.118.1.91","article-title":"Wrinkled1: A novel, low-seed-oil mutant of Arabidopsis with a deficiency in the seed-specific regulation of carbohydrate metabolism","volume":"118","author":"Focks","year":"1998","journal-title":"Plant Physiol."},{"key":"B26","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1186\/s13068-021-01928-8","article-title":"Ectopic overexpression of a type-II DGAT (CeDGAT2-2) derived from oil-rich tuber of Cyperus esculentus enhances accumulation of oil and oleic acid in tobacco leaves","volume":"14","author":"Gao","year":"2021","journal-title":"Biotechnol. Biofuels"},{"key":"B27","doi-asserted-by":"publisher","first-page":"14235","DOI":"10.1038\/s41598-017-14695-0","article-title":"WRKY43 regulates polyunsaturated fatty acid content and seed germination under unfavourable growth conditions","volume":"7","author":"Geilen","year":"2017","journal-title":"Sci. Rep."},{"key":"B28","doi-asserted-by":"publisher","first-page":"4892","DOI":"10.1105\/tpc.112.105114","article-title":"The SWI2\/SNF2 chromatin remodeling ATPase BRAHMA represses abscisic acid responses in the absence of the stress stimulus in Arabidopsis","volume":"24","author":"Han","year":"2012","journal-title":"Plant Cell"},{"key":"B29","doi-asserted-by":"publisher","first-page":"2762","DOI":"10.1016\/j.febslet.2014.05.061","article-title":"Wheat germ systems for cell-free protein expression","volume":"588","author":"Harbers","year":"2014","journal-title":"FEBS Lett."},{"key":"B30","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1104\/pp.114.253195","article-title":"ECERIFERUM2-LIKE proteins have unique biochemical and physiological functions in very-long-chain fatty acid elongation","volume":"167","author":"Haslam","year":"2015","journal-title":"Plant Physiol."},{"key":"B31","doi-asserted-by":"publisher","first-page":"1164","DOI":"10.1104\/pp.112.201640","article-title":"Arabidopsis ECERIFERUM2 is a component of the fatty acid elongation machinery required for fatty acid extension to exceptional lengths","volume":"160","author":"Haslam","year":"2012","journal-title":"Plant Physiol."},{"key":"B32","doi-asserted-by":"publisher","first-page":"3030","DOI":"10.1093\/jxb\/erac084","article-title":"Different acyl-CoA: diacylglycerol acyltransferases vary widely in function, and a targeted amino acid substitution enhances oil accumulation","volume":"73","author":"Hatanaka","year":"2022","journal-title":"J. Exp. Bot."},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1093\/plcell\/koaf135","article-title":"The histone acetyltransferase GCN5 regulates foral meristem activity and flower development in Arabidopsis","volume":"37","author":"Hawar","year":"2025","journal-title":"Plant Cell"},{"key":"B34","doi-asserted-by":"publisher","first-page":"1520","DOI":"10.1105\/tpc.18.00825","article-title":"The transcription factor INDUCER OF CBF EXPRESSION1 interacts with ABSCISIC ACID INSENSITIVE5 and DELLA proteins to fine-tune abscisic acid signaling during seed germination in Arabidopsis","volume":"31","author":"Hu","year":"2019","journal-title":"Plant Cell"},{"key":"B35","doi-asserted-by":"publisher","first-page":"4394","DOI":"10.1105\/tpc.114.130849","article-title":"BRASSINOSTEROID INSENSITIVE2 interacts with ABSCISIC ACID INSENSITIVE5 to mediate the antagonism of brassinosteroids to abscisic acid during seed germination in Arabidopsis","volume":"26","author":"Hu","year":"2014","journal-title":"Plant Cell"},{"key":"B36","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1105\/tpc.16.00623","article-title":"WIND 1 promotes shoot regeneration through transcriptional activation of ENHANCER OF SHOOT REGENERATION 1 in Arabidopsis","volume":"29","author":"Iwase","year":"2017","journal-title":"Plant Cell"},{"key":"B37","doi-asserted-by":"publisher","first-page":"2053","DOI":"10.1093\/plphys\/kiae188","article-title":"Abscisic acid activates transcription factor module MdABI5-MdMYBS1 during carotenoid-derived apple fruit coloration","volume":"195","author":"Jia","year":"2024","journal-title":"Plant Physiol."},{"key":"B38","doi-asserted-by":"publisher","first-page":"2389","DOI":"10.30848\/PJB2024-6(19)","article-title":"MYC2 involves in erucic acid synthesis by negatively regulating FAE1 transcription activity in Brassica napus","volume":"56","author":"Jiang","year":"2024","journal-title":"Pak. J. Bot."},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1016\/j.xplc.2025.101426","article-title":"ABA promotes fatty acid biosynthesis and transport to boost arbuscular mycorrhizal symbiosis in apple roots","volume":"6","author":"Jing","year":"2025","journal-title":"Plant Commun."},{"key":"B40","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1111\/nph.15757","article-title":"JAZ proteins modulated seed germination through interaction with ABI5 in bread wheat and Arabidopsis","volume":"223","author":"Ju","year":"2019","journal-title":"New Phytol."},{"key":"B41","doi-asserted-by":"publisher","first-page":"1346","DOI":"10.1111\/pbi.12354","article-title":"Senescence-inducible LEC2 enhances triacylglycerol accumulation in leaves without negatively affecting plant growth","volume":"13","author":"Kim","year":"2015","journal-title":"Plant Biotechnol. J."},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2022.1053735","article-title":"Editorial: dissection of the molecular basis of fatty acid composition in oil crops and molecular breeding of oil crops with improved fatty acid composition","volume":"13","author":"Kim","year":"2022","journal-title":"Front. Plant Sci."},{"key":"B43","doi-asserted-by":"publisher","first-page":"1432","DOI":"10.1093\/pcp\/pcy073","article-title":"The MYB96 transcription factor regulates triacylglycerol accumulation by activating DGAT1 and PDAT1 expression in Arabidopsis seeds","volume":"59","author":"Lee","year":"2018","journal-title":"Plant Cell Physiol."},{"key":"B44","doi-asserted-by":"publisher","first-page":"2823","DOI":"10.1105\/tpc.20.00352","article-title":"A SnRK1-ZmRFWD3-Opaque2 signaling axis regulates diurnal nitrogen accumulation in maize seeds","volume":"32","author":"Li","year":"2020","journal-title":"Plant Cell"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1016\/j.indcrop.2025.120758","article-title":"Metabolic pathway for evaluation of polyunsaturated fatty acids content variation and regulation of its biosynthesis in Paeonia ostii through abscisic acid and ABSCISIC ACID-INSENSITIVE 5 (PoABI5)","volume":"227","author":"Li","year":"2025","journal-title":"Ind. Crop Prod."},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1016\/j.plantsci.2022.111189","article-title":"ABSCISIC ACID-INSENSITIVE 5-\u03c93 FATTY ACID DESATURASE3 module regulates unsaturated fatty acids biosynthesis in Paeonia ostii","volume":"317","author":"Li","year":"2022","journal-title":"Plant Sci."},{"key":"B47","doi-asserted-by":"publisher","first-page":"4863","DOI":"10.1105\/tpc.113.118604","article-title":"ABA-INSENSITIVE3, ABA-INSENSITIVE5, and DELLAs interact to activate the expression of SOMNUS and other high-temperature-inducible genes in imbibed seeds in Arabidopsis","volume":"25","author":"Lim","year":"2013","journal-title":"Plant Cell"},{"key":"B48","doi-asserted-by":"publisher","first-page":"871","DOI":"10.1111\/jipb.13238","article-title":"Mediator complex subunit MED25 physically interacts with DST to regulate spikelet number in rice","volume":"64","author":"Lin","year":"2022","journal-title":"J. Integr. Plant Biol."},{"key":"B49","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1105\/tpc.18.00405","article-title":"MYC2 regulates the termination of jasmonate signaling via an autoregulatory negative feedback loop","volume":"31","author":"Liu","year":"2019","journal-title":"Plant Cell"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1016\/j.xplc.2025.101459","article-title":"A bHLH7-PDF2 module mediates transcriptional regulation to repress seed oil accumulation in Arabidopsis thaliana","volume":"6","author":"Liu","year":"2025","journal-title":"Plant Commun."},{"key":"B51","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2-\u0394\u0394CT method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"B52","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1046\/j.1365-313X.2002.01430.x","article-title":"ABI5 acts downstream of ABI3 to execute an ABA-dependent growth arrest during germination","volume":"32","author":"Lopez-Molina","year":"2002","journal-title":"Plant J."},{"key":"B53","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1111\/nph.17401","article-title":"A transcriptional regulatory module controls lipid accumulation in soybean","volume":"231","author":"Lu","year":"2021","journal-title":"New Phytol."},{"key":"B54","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1016\/j.molp.2020.11.011","article-title":"MPK14-mediate auxin signaling controls lateral root development via ERF13- regulated very-long-chain fatty acid biosynthesis","volume":"14","author":"Lv","year":"2021","journal-title":"Mol. Plant"},{"key":"B55","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1017\/S0960258513000305","article-title":"Expression analysis of seed-specific genes in four angiosperm species with an emphasis on the unconserved expression patterns of homologous genes","volume":"23","author":"Ma","year":"2013","journal-title":"Seed Sci. Res."},{"key":"B56","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1186\/s13068-016-0642-7","article-title":"Ectopic expression of AtDGAT1, encoding diacylglycerol O-acyltransferase exclusively committed to TAG biosynthesis, enhances oil accumulation in seeds and leaves of Jatropha","volume":"9","author":"Maravi","year":"2016","journal-title":"Bio\/Technol. Biofuels. Biop"},{"key":"B57","doi-asserted-by":"publisher","first-page":"1641","DOI":"10.1105\/tpc.113.111112","article-title":"A bHLH-type transcription factor, ABA-inducible bHLH-type transcription factor\/JA-associated MYC2-like1, acts as a repressor to negatively regulate jasmonate signaling in Arabidopsis","volume":"25","author":"Nakata","year":"2013","journal-title":"Plant Cell"},{"key":"B58","doi-asserted-by":"publisher","first-page":"E6710","DOI":"10.1073\/pnas.1707957114","article-title":"LEC1 sequentially regulates the transcription of genes involved in diverse developmental processes during seed development","volume":"114","author":"Pelletier","year":"2017","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B59","doi-asserted-by":"publisher","first-page":"2729","DOI":"10.1105\/tpc.108.061515","article-title":"The gibberellic acid signaling repressor RGL2 inhibits Arabidopsis seed germination by stimulating abscisic acid synthesis and ABI5 activity","volume":"20","author":"Piskurewicz","year":"2008","journal-title":"Plant Cell"},{"key":"B60","doi-asserted-by":"publisher","first-page":"575","DOI":"10.3109\/10409238.2013.840259","article-title":"The mediator complex and transcription regulation","volume":"48","author":"Poss","year":"2013","journal-title":"Crit. Rev. Biochem. Mol. Biol."},{"key":"B61","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1016\/j.tplants.2017.03.012","article-title":"Turning over a new leaf in lipid droplet biology","volume":"22","author":"Pyc","year":"2017","journal-title":"Trends Plant Sci."},{"key":"B62","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1111\/jipb.12914","article-title":"Oryza sativa mediator subunit OsMED25 interacts with OsBZR1 to regulate brassinosteroid signaling and plant architecture in rice","volume":"62","author":"Ren","year":"2020","journal-title":"J. Integr. Plant Biol."},{"key":"B63","doi-asserted-by":"publisher","first-page":"1373","DOI":"10.1002\/hep.1840210522","article-title":"Is dietary erucic acid hepatotoxic in pregnancy? An experimental study in rats and hamsters","volume":"21","author":"Reyes","year":"1995","journal-title":"Hepatology"},{"key":"B64","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1023\/A:1011603923889","article-title":"Expression of the FAE1 gene and FAE1 promoter activity in developing seeds of Arabidopsis thaliana","volume":"46","author":"Rossak","year":"2001","journal-title":"Plant Mol. Biol."},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1186\/s40538-025-00729-7","article-title":"The global energy challenge: second-generation feedstocks on marginal lands for a sustainable biofuel production","volume":"12","author":"Russo","year":"2025","journal-title":"Chem. Biol. Technol. Ag."},{"key":"B66","doi-asserted-by":"publisher","first-page":"1191","DOI":"10.1105\/tpc.000877","article-title":"Contrapuntal networks of gene expression during Arabidopsis seed filling","volume":"14","author":"Ruuska","year":"2002","journal-title":"Plant Cell"},{"key":"B67","doi-asserted-by":"publisher","first-page":"630","DOI":"10.1105\/tpc.19.00569","article-title":"Multilayered regulation of membrane-bound ONAC054 is essential for abscisic acid-induced leaf senescence in rice","volume":"32","author":"Sakuraba","year":"2020","journal-title":"Plant Cell"},{"key":"B68","doi-asserted-by":"publisher","first-page":"1909","DOI":"10.1105\/tpc.110.073874","article-title":"The Mg-chelatase H subunit of Arabidopsis antagonizes a group of WRKY transcription repressors to relieve ABA-responsive genes of inhibition","volume":"22","author":"Shang","year":"2010","journal-title":"Plant Cell"},{"key":"B69","doi-asserted-by":"publisher","first-page":"818","DOI":"10.1093\/plcell\/koab286","article-title":"A molecular switch for FLOWERING LOCUS C activation determines flowering time in Arabidopsis","volume":"34","author":"Shen","year":"2022","journal-title":"Plant Cell"},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2021.748130","article-title":"Abscisic acid improves linoleic acid accumulation possibly by promoting expression of EgFAD2 and other fatty acid biosynthesis genes in oil palm mesocarp","volume":"12","author":"Shi","year":"2021","journal-title":"Front. Plant Sci."},{"key":"B71","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1038\/s41477-019-0577-7","article-title":"Eight high-quality genomes reveal pan-genome architecture and ecotype differentiation of Brassica napus","volume":"6","author":"Song","year":"2020","journal-title":"Nat. Plants"},{"key":"B72","doi-asserted-by":"publisher","DOI":"10.1093\/hr\/uhac130","article-title":"Role of MaABI5-like in abscisic acid-induced cold tolerance of \u2018Fenjiao\u2019 banana fruit","volume":"9","author":"Song","year":"2022","journal-title":"Hortic. Res."},{"key":"B73","doi-asserted-by":"publisher","first-page":"1312","DOI":"10.1093\/plphys\/kiab532","article-title":"F-box protein EBF1 and transcription factor ABI5-like regulate banana fruit chilling-induced ripening disorder","volume":"188","author":"Song","year":"2022","journal-title":"Plant Physiol."},{"key":"B74","doi-asserted-by":"publisher","first-page":"612","DOI":"10.1111\/ppl.13082","article-title":"The WRKY6 transcription factor affects seed oil accumulation and alters fatty acid compositions in Arabidopsis thaliana","volume":"169","author":"Song","year":"2020","journal-title":"Physiol. Plant"},{"key":"B75","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1038\/nrm.2017.115","article-title":"Transcription regulation by the mediator complex","volume":"19","author":"Soutourina","year":"2018","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"B76","doi-asserted-by":"publisher","first-page":"1549","DOI":"10.1104\/pp.20.00587","article-title":"Mediator subunit MED25 physically interacts with PHYTOCHROME INTERACTING FACTOR4 to regulate shade-induced hypocotyl elongation in tomato","volume":"184","author":"Sun","year":"2020","journal-title":"Plant Physiol."},{"key":"B77","doi-asserted-by":"publisher","first-page":"1679","DOI":"10.1111\/tpj.14854","article-title":"Direct and indirect targets of the Arabidopsis seed transcription factor abscisic acid insensitive3","volume":"103","author":"Tian","year":"2020","journal-title":"Plant J."},{"key":"B78","doi-asserted-by":"publisher","first-page":"1369","DOI":"10.1111\/pbi.13061","article-title":"Expression of the Arabidopsis WRINKLED 1 transcription factor leads to higher accumulation of palmitate in soybean seed","volume":"17","author":"Vogel","year":"2019","journal-title":"Plant Biotechnol. J."},{"key":"B79","doi-asserted-by":"publisher","first-page":"762","DOI":"10.3724\/SP.J.1148.2008.00259","article-title":"Effect of NaCl stress on seed germination and stem apexes growth of rapeseed cultivars with high and low-erucic acid","volume":"22","author":"Wang","year":"2008","journal-title":"J. Nucl. Agric. Sci."},{"key":"B80","doi-asserted-by":"publisher","first-page":"2736","DOI":"10.1093\/plcell\/koab153","article-title":"Phosphorylation of WRKY16 by MPK3-1 is essential for its transcriptional activity during fiber initiation and elongation in cotton (Gossypium hirsutum)","volume":"33","author":"Wang","year":"2021","journal-title":"Plant Cell"},{"key":"B81","doi-asserted-by":"publisher","first-page":"1251","DOI":"10.1104\/pp.112.212282","article-title":"Identification of direct targets of FUSCA3, a key regulator of Arabidopsis seed development","volume":"161","author":"Wang","year":"2013","journal-title":"Plant Physiol."},{"key":"B82","doi-asserted-by":"publisher","first-page":"2309","DOI":"10.1093\/plphys\/kiae146","article-title":"Abscisic acid-insensitive 5-kip-related protein 1-shoot meristemless modulates reproductive development of Arabidopsis","volume":"195","author":"Wang","year":"2024","journal-title":"Plant Physiol."},{"key":"B83","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2021.722596","article-title":"EgmiR5179 regulates lipid metabolism by targeting EgMADS16 in the mesocarp of oil palm (Elaeis guineensis)","volume":"12","author":"Wang","year":"2021","journal-title":"Front. Plant Sci."},{"key":"B84","doi-asserted-by":"publisher","first-page":"626","DOI":"10.1104\/pp.113.216820","article-title":"In vivo packaging of triacylglycerols enhances Arabidopsis leaf biomass and energy density","volume":"162","author":"Winichayakul","year":"2013","journal-title":"Plant Physiol."},{"key":"B85","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1105\/tpc.19.00583","article-title":"Mediator subunit MED25 couples alternative splicing of JAZ genes with fine-tuning of jasmonate signaling","volume":"32","author":"Wu","year":"2020","journal-title":"Plant Cell"},{"key":"B86","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2019.01389","article-title":"Expression analysis and functional characterization of CER1 family genes involved in very-long-chain alkanes biosynthesis in Brachypodium distachyon","volume":"10","author":"Wu","year":"2019","journal-title":"Front. Plant Sci."},{"key":"B87","doi-asserted-by":"publisher","first-page":"2205","DOI":"10.1093\/plcell\/koac077","article-title":"Embryonic reactivation of FLOWERING LOCUS C by abscisic acid-insensitive 3 establishes the vernalization requirement in each Arabidopsis generation","volume":"34","author":"Xu","year":"2022","journal-title":"Plant Cell"},{"key":"B88","doi-asserted-by":"publisher","first-page":"1997","DOI":"10.1093\/plphys\/kiad200","article-title":"The transcription factor PbrMYB24 regulates lignin and cellulose biosynthesis in stone cells of pear fruits","volume":"192","author":"Xue","year":"2023","journal-title":"Plant Physiol."},{"key":"B89","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1007\/s10725-012-9727-x","article-title":"Maize (Zea mays L.) homologue of ABA-insensitive (ABI)5 gene plays a negative regulatory role in abiotic stresses response","volume":"68","author":"Yan","year":"2012","journal-title":"Plant Growth Regul."},{"key":"B90","doi-asserted-by":"publisher","first-page":"2011","DOI":"10.1111\/pbi.13628","article-title":"DELLA proteins BnaA6.RGA and BnaC7.RGA negatively regulate fatty acid biosynthesis by interacting with BnaLEC1s in Brassica napus","volume":"19","author":"Yan","year":"2021","journal-title":"Plant Biotechnol. J."},{"key":"B91","doi-asserted-by":"publisher","first-page":"3022","DOI":"10.1093\/plcell\/koab168","article-title":"The Arabidopsis circadian clock protein PRR5 interacts with and stimulates ABI5 to modulate abscisic acid signaling during seed germination","volume":"33","author":"Yang","year":"2021","journal-title":"Plant Cell"},{"key":"B92","doi-asserted-by":"publisher","DOI":"10.1016\/j.xplc.2022.100328","article-title":"Transcriptional regulation of oil biosynthesis in seed plants: current understanding, applications, and perspectives","volume":"3","author":"Yang","year":"2022","journal-title":"Plant Commun."},{"key":"B93","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1016\/j.molp.2023.03.007","article-title":"BnIR: a multi-omics database with various tools for Brassica napus research and breeding","volume":"16","author":"Yang","year":"2023","journal-title":"Mol. Plant"},{"key":"B94","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1111\/tpj.13549","article-title":"WRI1-1, ABI5, NF-YA3 and NF-YC2 increase oil biosynthesis in coordination with hormonal signaling during fruit development in oil palm","volume":"91","author":"Yeap","year":"2017","journal-title":"Plant J."},{"key":"B95","doi-asserted-by":"publisher","DOI":"10.1002\/pld3.343","article-title":"Sesamum indicum Oleosin L improves oil packaging in Nicotiana benthamiana leaves","volume":"5","author":"Yee","year":"2021","journal-title":"Plant Direct"},{"key":"B96","doi-asserted-by":"publisher","first-page":"2187","DOI":"10.1105\/tpc.19.00115","article-title":"LEUNIG_HOMOLOG mediates MYC2-dependent transcriptional activation in cooperation with the coactivators HAC1 and MED25","volume":"31","author":"You","year":"2019","journal-title":"Plant Cell"},{"key":"B97","first-page":"48","article-title":"Effects of erucic acid on wheat seedling and some physiological parameters","volume":"5","author":"Yue","year":"2018","journal-title":"J. Gansu Normal Colleges"},{"key":"B98","doi-asserted-by":"publisher","first-page":"3415","DOI":"10.1093\/jxb\/erz233","article-title":"The plant mediator complex and its role in jasmonate signaling","volume":"70","author":"Zhai","year":"2019","journal-title":"J. Exp. Bot."},{"key":"B99","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1186\/s13059-025-03558-x","article-title":"Integrative omics analysis reveals the genetic basis of fatty acid composition in Brassica napus seeds","volume":"26","author":"Zhang","year":"2025","journal-title":"Genome Biol."},{"key":"B100","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1007\/s42994-025-00217-4","article-title":"Mutation of ERECTA homologous genes confers ideal plant architecture in Brassica napus","volume":"6","author":"Zhang","year":"2025","journal-title":"aBIOTECH"},{"key":"B101","doi-asserted-by":"publisher","first-page":"4294","DOI":"10.1105\/tpc.112.103317","article-title":"The Arabidopsis mediator complex subunit16 positively regulates salicylate-mediated systemic acquired resistance and jasmonate\/ethylene-induced defense pathways","volume":"24","author":"Zhang","year":"2012","journal-title":"Plant Cell"},{"key":"B102","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1111\/jipb.13826","article-title":"Apple MIEL1\/ABI5-MAX2 regulatory module links strigolactone and abscisic acid signals","volume":"67","author":"Zhang","year":"2025","journal-title":"J. Integra. Plant Biol."},{"key":"B103","doi-asserted-by":"publisher","first-page":"2735","DOI":"10.1105\/tpc.16.00470","article-title":"ABI5 is a regulator of seed maturation and longevity in legumes","volume":"28","author":"Zinsmeister","year":"2016","journal-title":"Plant Cell"}],"container-title":["Frontiers in Plant Science"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpls.2026.1798651\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T04:29:53Z","timestamp":1781065793000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpls.2026.1798651\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,10]]},"references-count":103,"alternative-id":["10.3389\/fpls.2026.1798651"],"URL":"https:\/\/doi.org\/10.3389\/fpls.2026.1798651","relation":{},"ISSN":["1664-462X"],"issn-type":[{"value":"1664-462X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,10]]},"article-number":"1798651"}}