{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T12:57:14Z","timestamp":1781182634260,"version":"3.54.1"},"reference-count":47,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T00:00:00Z","timestamp":1781136000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Plant Sci."],"abstract":"<jats:p>\n                    <jats:italic>Artemisia annua<\/jats:italic>\n                    is the source plant for artemisinin production. Variable cultivation conditions are important factors affecting plant growth and artemisinin yield. The jasmonic acid signaling pathway is a crucial mechanism by which plants cope with stress, with the jasmonate ZIM-domain (\n                    <jats:italic>JAZ<\/jats:italic>\n                    ) genes playing key roles in this pathway. While the\n                    <jats:italic>JAZ<\/jats:italic>\n                    gene family in\n                    <jats:italic>A. annua<\/jats:italic>\n                    has not yet been comprehensively characterized, this study conducted an in-depth analysis of\n                    <jats:italic>JAZ<\/jats:italic>\n                    genes, including identification and molecular characteristics such as genetic variation and alternative splicing, as well as short-term expression responses to methyl jasmonate (MeJA) in the LQ-9 genotype. The results showed that 18\n                    <jats:italic>AaJAZ<\/jats:italic>\n                    genes were identified in the h0 haplotype, whereas 17 were identified in the h1 haplotype. A total of 967 single nucleotide polymorphisms (SNPs) and 267 insertion\/deletion (indels) were identified across 17 pairs of alleles, and four\n                    <jats:italic>AaJAZ<\/jats:italic>\n                    genes showed alternative splicing events. Ten other Aa\n                    <jats:italic>JAZ<\/jats:italic>\n                    genes exhibited specific and significant induction by MeJA exclusively in old leaves. Through gene expression profiling and protein-protein interaction validation, AaJAZ8 was found to form homodimers and interact with 10 AaJAZs. Additionally, yeast two-hybrid assays suggested potential physical interactions between AaJAZ8 and both AaMYC24 and AaMYC26. This study systematically characterizes the JAZ protein family in\n                    <jats:italic>A. annua<\/jats:italic>\n                    , identified novel AaJAZ8-interacting proteins, and provides a foundation for further understanding the role of\n                    <jats:italic>AaJAZ8<\/jats:italic>\n                    in the jasmonate signaling network.\n                  <\/jats:p>","DOI":"10.3389\/fpls.2026.1855917","type":"journal-article","created":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T12:01:48Z","timestamp":1781179308000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["AaJAZ8 forms an extensive interaction network with AaJAZ proteins and two novel AaMYC transcription factors in Artemisia annua"],"prefix":"10.3389","volume":"17","author":[{"given":"Xianchun","family":"Zong","sequence":"first","affiliation":[{"name":"College of Life Science and Technology, Mudanjiang Normal University","place":["Mudanjiang, Heilongjiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaoxue","family":"Ma","sequence":"additional","affiliation":[{"name":"College of Life Science and Technology, Mudanjiang Normal University","place":["Mudanjiang, Heilongjiang, China"]},{"name":"The Second Clinical College, Guangzhou University of Chinese","place":["Medicine, Guangzhou, Guangdong, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baosheng","family":"Liao","sequence":"additional","affiliation":[{"name":"The Second Clinical College, Guangzhou University of Chinese","place":["Medicine, Guangzhou, Guangdong, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,6,11]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21020621","article-title":"Jasmonic acid signaling pathway in response to abiotic stresses in plants","volume":"21","author":"Ali","year":"2020","journal-title":"Int. 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