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This paper reviews the resource distribution and quality correlation, development trends, chemical constituents, biological activities, clinical applications, and current product development status of\n                    <jats:italic>Dendrobium officinale<\/jats:italic>\n                    and other medicinal plants within the Dendrobium genus. It highlights the structural characteristics and pharmacological effects of key active components such as polysaccharides, alkaloids, and dibenzyl compounds, summarizes their mechanisms of action in immune regulation, antioxidant properties, and eye health protection, and supplements the influence of different origins and cultivation models on active components. The paper also provides an outlook on the current status of product development and future trends.\n                  <\/jats:p>","DOI":"10.3389\/fpls.2026.1864437","type":"journal-article","created":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T15:24:43Z","timestamp":1782401083000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Merits of bioactivity and products of Dendrobium officinale and other related species"],"prefix":"10.3389","volume":"17","author":[{"given":"Shaojun","family":"Wu","sequence":"first","affiliation":[{"name":"School of Life Sciences and Medicine, Zhejiang Sci-Tech University","place":["Hangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinchuan","family":"He","sequence":"additional","affiliation":[{"name":"School of Life Sciences and Medicine, Zhejiang Sci-Tech University","place":["Hangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanli","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Life Sciences and Medicine, Zhejiang Sci-Tech University","place":["Hangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haihua","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Life Sciences and Medicine, Zhejiang Sci-Tech University","place":["Hangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaodan","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Life Sciences and Medicine, Zhejiang Sci-Tech University","place":["Hangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zongsuo","family":"Liang","sequence":"additional","affiliation":[{"name":"School of Life Sciences and Medicine, Zhejiang Sci-Tech University","place":["Hangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,6,25]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.3390\/plants13212961","article-title":"Challenges and strategies in the industrial application of Dendrobium officinale","volume":"13","author":"Bao","year":"2024","journal-title":"Plants"},{"key":"B2","unstructured":"Analysis Report on the Current Market Situation and Future Prospect Planning of China\u2019s Dendrobium Industry From 2026 to 2032\n          \n          2026"},{"key":"B3","doi-asserted-by":"publisher","first-page":"827","DOI":"10.14336\/AD.2017.0214","article-title":"Dendrobium: sources of active ingredients to treat age-related pathologies","volume":"8","author":"Cakova","year":"2017","journal-title":"Aging Dis."},{"key":"B4","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/j.jep.2018.09.001","article-title":"An assessment of the chinese medicinal dendrobium industry: supply, demand and sustainability","volume":"229","author":"Chen","year":"2019","journal-title":"J. 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