{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T06:24:46Z","timestamp":1787639086947,"version":"build-2736575974"},"reference-count":116,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T00:00:00Z","timestamp":1787616000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Plant Sci."],"abstract":"<jats:p>\n                    The cuticle represents the outer most protective barrier against biotic and abiotic stresses. It is composed of cutin and waxes and protects plants from desiccation, UV, cold, mechanical stresses, and pathogens. GWAS\/BSAseq combined with SeqSNP analyses in an association panel of 34 potato cultivars had revealed that the acyl-ACP thioesterase FATA (Soltu.DM.06G033680.1) is significantly associated with drought tolerance in potato. Apart from three\n                    <jats:italic>FATB<\/jats:italic>\n                    genes, only one\n                    <jats:italic>FATA<\/jats:italic>\n                    gene is present in potato that has the highest homology to\n                    <jats:italic>FATA2<\/jats:italic>\n                    in Arabidopsis. FATA is responsible for the export of C18:1 fatty acid from chloroplast into cytosol, which is necessary for the biosynthesis of cutin. A knockout mutant of\n                    <jats:italic>AtFATA2<\/jats:italic>\n                    was analyzed with regard to the cuticle permeability and to drought tolerance as well as recovery. Loss of FATA function leads to higher sensibility to water deficit in Arabidopsis, but to no change in recovery. The increased permeability of the cuticle in the\n                    <jats:italic>fata2<\/jats:italic>\n                    knockout mutant as shown indirectly by higher chlorophyll leaching might play a role in this. Haplotypes for FATA were identified for the two potato cultivars Albatros and D\u00e9sir\u00e9e. All D\u00e9sir\u00e9e haplotypes and Albatros haplotypes 1, 3 and 4 were also revealed by former potato pan genome studies, while Albatros haplotype 2 is unique and has not been described before. Protein models were developed to investigate the influence of different SNPs in the haplotypes on the predicted protein structure and especially the substrate cavity. In potato, protein modeling suggests that only the hypothetical isoform B of FATA might be able to process oleoyl-ACP, but not hypothetical isoform A. However, this hypothesis needs to be verified by enzyme activity assays.\n                  <\/jats:p>","DOI":"10.3389\/fpls.2026.1917461","type":"journal-article","created":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T05:35:42Z","timestamp":1787636142000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Genome-wide analysis of FATA associated with drought tolerance in tetraploid potato (Solanum tuberosum)"],"prefix":"10.3389","volume":"17","author":[{"given":"Florian","family":"Schilling","sequence":"first","affiliation":[{"name":"Institute of Biological Sciences, Department of Plant Genetics, University of Rostock","place":["Rostock, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annika","family":"Reimer","sequence":"additional","affiliation":[{"name":"Institute of Biological Sciences, Department of Plant Genetics, University of Rostock","place":["Rostock, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renate","family":"Horn","sequence":"additional","affiliation":[{"name":"Institute of Biological Sciences, Department of Plant Genetics, University of Rostock","place":["Rostock, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,8,25]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1007\/s11540-021-09527-8","article-title":"Transcriptomic responses of potato to drought stress","volume":"65","author":"Aliche","year":"2021","journal-title":"Potato Res."},{"key":"B2","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1016\/S0022-2836(05)80360-2","article-title":"Basic local alignment search tool","volume":"215","author":"Altschul","year":"1990","journal-title":"J. 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