{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T07:15:47Z","timestamp":1788419747545,"version":"build-2803163510"},"reference-count":38,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T00:00:00Z","timestamp":1788393600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Plant Sci."],"abstract":"<jats:p>\n                    <jats:italic>Amomum tsao-ko<\/jats:italic>\n                    is a valuable medicinal and culinary resource, yet its non-volatile terpenoid composition remains poorly characterized. This study integrated widely targeted metabolomics and transcriptomics to systematically profile non-volatile terpenoids in\n                    <jats:italic>A. tsao-ko<\/jats:italic>\n                    fruits and investigate the impacts of fruit morphotype and drying process. Using UPLC-MS\/MS, 157 non-volatile terpenoids were identified, with 147 common across all samples, indicating a stable core metabolome. Fruit shape significantly influenced terpenoid accumulation, with round fruits generally exhibiting higher levels, and Caesalpin J identified as a shape-discriminatory marker. Drying induced profound alterations, promoting glycosylated forms while reducing free sesquiterpenoids and diterpenoids. Isosteviol was exclusively detected in dried fruits, serving as a drying-specific marker. Transcriptomic analysis revealed 49 shape-responsive differentially expressed genes enriched in terpenoid biosynthesis pathways. Weighted gene co-expression network analysis identified a terpenoid-associated module containing key structural genes and transcription factors. These findings provide a foundational chemical and molecular atlas for quality assessment, germplasm innovation, and optimized processing of\n                    <jats:italic>A. tsao-ko<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.3389\/fpls.2026.1937993","type":"journal-article","created":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T06:44:05Z","timestamp":1788417845000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Multi-omics analysis reveals shape- and drying-dependent variation in non-volatile terpenoids of Amomum tsao-ko fruits"],"prefix":"10.3389","volume":"17","author":[{"given":"Mengli","family":"Ma","sequence":"first","affiliation":[{"name":"Yunnan Provincial Key Laboratory of Cross-Border Chinese Herbal Material, College of Agronomy, Honghe University","place":["Mengzi, Yunnan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina","family":"Xiong","sequence":"additional","affiliation":[{"name":"Yunnan Provincial Key Laboratory of Cross-Border Chinese Herbal Material, College of Agronomy, Honghe University","place":["Mengzi, Yunnan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongbo","family":"Fu","sequence":"additional","affiliation":[{"name":"Yunnan Provincial Key Laboratory of Cross-Border Chinese Herbal Material, College of Agronomy, Honghe University","place":["Mengzi, Yunnan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingyue","family":"Lu","sequence":"additional","affiliation":[{"name":"Yunnan Provincial Key Laboratory of Cross-Border Chinese Herbal Material, College of Agronomy, Honghe University","place":["Mengzi, Yunnan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,3]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.3390\/plants13020300","article-title":"Phenotypic and genotypic variation of cultivated Panax quinquefolius","volume":"13","author":"Abaya","year":"2024","journal-title":"Plants (Basel. 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