{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T06:08:32Z","timestamp":1789711712631,"version":"4.0.1"},"reference-count":115,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T00:00:00Z","timestamp":1789689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Plant Sci."],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Ultraviolet-B radiation can enhance the accumulation of major chemical classes in medicinal plants but may simultaneously induce oxidative stress and cellular damage. Balancing these opposing effects is therefore critical for the effective application of UV-B in cultivation practices.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      In this study,\n                      <jats:italic>Dendrobium nobile<\/jats:italic>\n                      Lindl. plants were exposed to five different UV-B intensities (0, 20, 40, 80, and 160 \u03bcW cm-2) for 21 days. We systematically evaluated physiological parameters, measured the contents of major chemical classes (polyphenols, flavonoids, alkaloids, and polysaccharides), and performed transcriptomic profiling to investigate the underlying regulatory mechanisms.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Plants exhibited strong acclimation to 20 \u03bcW cm-2 UV-B, with contents of polyphenols, flavonoids, alkaloids, and polysaccharides increasing by 41.0%, 16.3%, 33.1%, and 19.3%, respectively (P &amp;lt; 0.05), while maintaining relatively low stress levels. Transcriptomic analysis revealed that at 20 \u03bcW cm\u207b\u00b2, transcription factors including\n                      <jats:italic>DnHY5, DnPCL1, DnMYBx1, DnBIM2, DnSCL9-l, DnMYBS3, DnBHLH66-l, DnWRKY2, DnPCF2, DnC3H2<\/jats:italic>\n                      , and\n                      <jats:italic>DnC3H14<\/jats:italic>\n                      may be involved in photomorphogenic acclimation, with key biosynthetic genes (\n                      <jats:italic>DnC4H, DnCAD, DnCHI, DnCHS, DnPOD12, DnMVK, DnMVD<\/jats:italic>\n                      ) upregulated. In contrast, 80 \u03bcW cm-2 UV-B induced evident stress damage and activated stress-responsive genes (\n                      <jats:italic>DnXTH, DnCYP77A6, DnCER1, DnCry-DASH, DnPHR, DnH64PHR<\/jats:italic>\n                      ), while suppressing several chemical biosynthesis-related genes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>\n                      These findings demonstrate that low-intensity UV-B (20 \u03bcW cm-2) promotes major chemical classes accumulation through photomorphogenic acclimation without significant stress damage, whereas high-intensity UV-B (80 \u03bcW cm-2) induces non-specific stress responses. This study provides a mechanistic framework for strategic UV-B application to improve medicinal plant quality and suggests optimized cultivation protocols for high-quality\n                      <jats:italic>D. nobile<\/jats:italic>\n                      production.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpls.2026.1953265","type":"journal-article","created":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T05:36:00Z","timestamp":1789709760000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Mechanisms of acclimation regulation and stress response to UV-B in Dendrobium nobile Lindl."],"prefix":"10.3389","volume":"17","author":[{"given":"Jie","family":"Ma","sequence":"first","affiliation":[{"name":"Department of Landscape Plants, Sichuan Agricultural University","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuyang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Landscape Plants, Sichuan Agricultural University","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yijun","family":"Fan","sequence":"additional","affiliation":[{"name":"Department of Landscape Plants, Sichuan Agricultural University","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Landscape Plants, Sichuan Agricultural University","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengjie","family":"Yuan","sequence":"additional","affiliation":[{"name":"Department of Landscape Plants, Sichuan Agricultural University","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunhong","family":"Mou","sequence":"additional","affiliation":[{"name":"Department of Landscape Plants, Sichuan Agricultural University","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao","family":"Zhong","sequence":"additional","affiliation":[{"name":"Department of Landscape Plants, Sichuan Agricultural University","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Landscape Plants, Sichuan Agricultural University","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haolin","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Landscape Plants, Sichuan Agricultural University","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junlan","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Landscape Plants, Sichuan Agricultural University","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaqing","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Landscape Plants, Sichuan Agricultural University","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinxing","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Landscape Plants, Sichuan Agricultural University","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinglong","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Landscape Plants, Sichuan Agricultural University","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aoxue","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Landscape Plants, Sichuan Agricultural University","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,18]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/S0076-6879(84)05016-3","article-title":"Catalase in vitro","volume":"105","author":"Aebi","year":"1984","journal-title":"Methods Enzymol."},{"key":"B2","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/0009-2797(93)90112-C","article-title":"A new direct method for determining superoxide dismutase 562 activity by measuring hydrogen peroxide formation","volume":"86","author":"Aguilar","year":"1993","journal-title":"Chem. 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