{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:26:16Z","timestamp":1787027176314,"version":"build-2736575974"},"reference-count":67,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T00:00:00Z","timestamp":1648684800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["71673052"],"award-info":[{"award-number":["71673052"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychol."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The Coronavirus 2019 (COVID-19) outbreak has led to a considerable proportion of adverse psychological symptoms in different subpopulations. This study aimed to investigate the status of anxiety and depression and their associated factors in the adult, working-age population in Mainland China at the early remission stage of the COVID-19 pandemic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>An online study was conducted among 1,863 participants in 29 provinces in Mainland China from March 23 to 31, 2020. Their mental health was evaluated by the generalized anxiety disorder scale (GAD-7) and the patient health questionnaire (PHQ-9). Descriptive analysis, Chi-square, and multiple logistic regressions were applied.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>About 44.5% of the participants had anxiety, 49.2% had depression, and 37.9% showed a combination of depression and anxiety. Around 83.7% of the participants claimed that the pandemic had a negative impact on their medical needs, which was the primary predictor of mental health, the degree of impact being positively related to the prevalence of anxiety and depression. More chronic diseases, moderate to bad self-rated health, severe perceived infection risk, and younger age group were the common risk factors for anxiety and depression. Having no children, unemployment, and a college-level educational background were associated with higher anxiety prevalence, whereas unmarried participants were correlated with higher depression prevalence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The working-age population showed a relatively high risk of anxiety and depression in Mainland China at the early remission stage of the pandemic. To improve medical services capacity for routine and delayed medical service needs should be a part of policy-makers\u2019 priority agenda during this period of crisis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpsyg.2022.839852","type":"journal-article","created":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T11:46:28Z","timestamp":1648727188000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":7,"title":["The Prevalence of and Factors Associated With Anxiety and Depression Among Working-Age Adults in Mainland China at the Early Remission Stage of the Coronavirus 2019 Pandemic"],"prefix":"10.3389","volume":"13","author":[{"given":"Haixia","family":"Xie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaowei","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuheng","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengshui","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuyin","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,3,31]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"102092","DOI":"10.1016\/j.ajp.2020.102092","article-title":"Epidemic of COVID-19 in China and associated psychological problems","volume":"51","author":"Ahmed","year":"2020","journal-title":"Asian J. 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J."},{"key":"ref43","author":"Wang","year":"2013"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1097\/PSY.0000000000000892","article-title":"Mental health and psychological responses during the coronavirus disease 2019 epidemic: a comparison between Wuhan and other areas in China","volume":"83","author":"Wang","year":"","journal-title":"Psychosom. Med."},{"key":"ref45","doi-asserted-by":"publisher","first-page":"864","DOI":"10.3969\/j.issn.1006-3110.2021.07.024","article-title":"Analysis of anxiety status and its influencing factors of residents in Hubei Province during COVID-19 epidemic","volume":"28","author":"Wang","year":"","journal-title":"Pract. Prev. Med."},{"key":"ref46","doi-asserted-by":"publisher","first-page":"142","DOI":"10.13912\/j.cnki.chqm.2020.27.4.38","article-title":"Investigation and analysis of hospital operation in COVID-19 epidemic","volume":"27","author":"Wang","year":"","journal-title":"Chin. Health Quality Manag."},{"key":"ref47","doi-asserted-by":"publisher","first-page":"4813","DOI":"10.1038\/s41380-021-01019-y","article-title":"The impact of quarantine on mental health status among general population in China during the COVID-19 pandemic","volume":"26","author":"Wang","year":"","journal-title":"Mol. Psychiatry"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1186\/s12888-021-03108-2","article-title":"Depressive, anxiety, and insomnia symptoms between population in quarantine and general population during the COVID-19 pandemic: A case-controlled study","volume":"21","author":"Wang","year":"","journal-title":"BMC Psychiatry"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"e0246824","DOI":"10.1371\/journal.pone.0246824","article-title":"The impact of COVID-19 pandemic on physical and mental health of Asians: A study of seven middle-income countries in Asia","volume":"16","author":"Wang","year":"","journal-title":"PLoS One"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1016\/j.psym.2020.05.005","article-title":"Psychological influence of coronovirus disease 2019 (COVID-19) pandemic on the general public, medical workers, and patients with mental disorders and its countermeasures","volume":"61","author":"Wang","year":"","journal-title":"Psychosomatics"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"e77","DOI":"10.1192\/j.eurpsy.2020.78","article-title":"Psychological distress and sleep problems when people are under interpersonal isolation during an epidemic: A nationwide multicenter cross-sectional study","volume":"63","author":"Wang","year":"","journal-title":"Eur. Psychiatry"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1016\/j.jad.2020.11.118","article-title":"Prevalence of psychological disorders in the COVID-19 epidemic in China: a real world cross-sectional study","volume":"281","author":"Wang","year":"","journal-title":"J. Affect. Disord."},{"key":"ref53","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1016\/j.outlook.2021.03.020","article-title":"Associations between COVID-19 perceptions, anxiety, and depressive symptoms among adults living in the United States","volume":"69","author":"Wierenga","year":"2021","journal-title":"Nurs. Outlook"},{"key":"ref54","year":"2020"},{"key":"ref55","year":"2022"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s12144-021-01953-8","article-title":"Using fear appeal theories to understand the effects of location information of patients on citizens during the COVID-19 pandemic","author":"Wu","year":"","journal-title":"Curr. 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