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Modern progress in the recording of changing brain functions during the time between clinical death and brain death opened the perspective to address and understand the generation of NDEs in brain states of altered consciousness. Changes of consciousness can experimentally be induced in well-controlled clinical or laboratory settings. Reports of the persons having experienced the changes can inform about the similarity of the experiences with those from original NDEs. Thus, we collected neuro-functional models of NDEs including OBEs with experimental backgrounds of drug consumption, epilepsy, brain stimulation, and ischemic stress, and included so far largely unappreciated data from fighter pilot tests under gravitational stress generating cephalic nervous system ischemia. Since we found a large overlap of NDE themes or topics from original NDE reports with those from neuro-functional NDE models, we can state that, collectively, the models offer scientifically appropriate causal explanations for the occurrence of NDEs. The generation of OBEs, one of the NDE themes, can be localized in the temporo-parietal junction (TPJ) of the brain, a multimodal association area. The evaluated literature suggests that NDEs may emerge as hallucination-like phenomena from a brain in altered states of consciousness (ASCs).<\/jats:p>","DOI":"10.3389\/fpsyg.2022.846159","type":"journal-article","created":{"date-parts":[[2023,1,18]],"date-time":"2023-01-18T15:55:27Z","timestamp":1674057327000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":8,"title":["Neuro-functional modeling of near-death experiences in contexts of altered states of consciousness"],"prefix":"10.3389","volume":"13","author":[{"given":"Raymond","family":"Romand","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00fcnter","family":"Ehret","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2023,1,18]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/j.neuron.2011.04.006","article-title":"Out-of-place bodies, out-of-body selves.","volume":"70","author":"Aglioti","year":"2011","journal-title":"Neuron"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1037\/a0021992","article-title":"Near-death experience: Out-of-body and out-of-brain.","volume":"15","author":"Agrillo","year":"2011","journal-title":"Rev. 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