{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T23:33:46Z","timestamp":1788478426944,"version":"build-2803163510"},"reference-count":72,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T00:00:00Z","timestamp":1745971200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychol."],"abstract":"<jats:sec><jats:title>Background and aims<\/jats:title><jats:p>Sedentary behavior (SB) is a prevalent lifestyle factor and a risk factor for various health conditions, including depression (encompassing both clinically diagnosed depressive disorders and depressive symptoms). This study aimed to summarize the estimated impact of reallocating time spent in SB to light-intensity physical activity (LPA) or moderate-to-vigorous physical activity (MVPA) on the risk of depression from observational studies, as well as the impact of reallocating time spent in MVPA and LPA to SB.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Four databases [PubMed, Scopus, SPORTdiscus, and PsycINFO (via EBSCOhost platform)] were searched and analyzed for relevant studies published up to August 2024. Meta-analyses were performed on the estimated regression coefficients (b) and 95% confidence intervals (CIs) for depression symptom scores. All statistical analyses were performed using STATA 16.0.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty-seven studies involving 702,755 participants met the inclusion criteria. Reallocating SB to LPA and MVPA was significantly associated with reductions in depression risk (<jats:italic>b<\/jats:italic> = \u22120.04, 95% CI = \u22120.06 to \u22120.03, <jats:italic>p<\/jats:italic> &amp;lt; 0.001; <jats:italic>b<\/jats:italic> = \u22120.11, 95% CI = \u22120.19 to \u22120.03, <jats:italic>p<\/jats:italic> = 0.004). Subgroup analyses indicated that reallocating 30 and 60 min of SB to LPA or MVPA was significantly associated with reduced depression risk, with significant differences in PA intensity and age, but not for 10 and 15 min groups. Conversely, reallocating LPA and MVPA to SB was significantly associated with increased depression risk (<jats:italic>b<\/jats:italic> = 0.11, 95% CI = 0.01 to 0.21, <jats:italic>p<\/jats:italic> = 0.039; <jats:italic>b<\/jats:italic> = 0.17, 95% CI = 0.08 to 0.25, <jats:italic>p<\/jats:italic> &amp;lt; 0.001). Subgroup analyses indicated that reallocating 30 min of LPA or MVPA to SB was significantly associated with increased depression risk, with no difference in PA intensity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Reallocating SB to PA was beneficial, whereas reallocating PA to SB was detrimental to the risk of depression. The results highlight the importance of considering PA intensity and duration in the development of behavioral guidelines aimed at reducing the risk of depression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Systematic review registration<\/jats:title><jats:p><jats:ext-link>https:\/\/www.crd.york.ac.uk\/PROSPERO\/display_record.php?RecordID=546666<\/jats:ext-link>, identifier: CRD42024546666.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpsyg.2025.1505061","type":"journal-article","created":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T05:39:03Z","timestamp":1745991543000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Association of reallocating time between physical activity and sedentary behavior on the risk of depression: a systematic review and meta-analysis"],"prefix":"10.3389","volume":"16","author":[{"given":"Yue","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuheng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiali","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Songtao","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,4,30]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"185","DOI":"10.7600\/jspfsm.71.185","article-title":"Cross-sectional associations between replacing sedentary behavior with physical activity by accelerometer-measured and depression in frail older adults: an isotemporal substitution approach","volume":"71","author":"Araki","year":"2022","journal-title":"Japanese J. Phys. Fit. Sports Med."},{"key":"B2","doi-asserted-by":"publisher","first-page":"596367","DOI":"10.1155\/2015\/596367","article-title":"Effects of light intensity activity on CVD risk factors: a systematic review of intervention studies","volume":"2015","author":"Batacan","year":"2015","journal-title":"BioMed Res. Int"},{"key":"B3","doi-asserted-by":"publisher","first-page":"2280","DOI":"10.3390\/ijerph15102280","article-title":"Associations of physical behaviours and behavioural reallocations with markers of metabolic health: a compositional data analysis","volume":"15","author":"Biddle","year":"2018","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"B4","doi-asserted-by":"publisher","first-page":"2497","DOI":"10.1007\/s00221-020-05866-z","article-title":"The effect of breaking up prolonged sitting on paired associative stimulation-induced plasticity","volume":"238","author":"Bojsen-M\u00f8ller","year":"2020","journal-title":"Exp. Brain Res."},{"key":"B5","volume-title":"Development of Evidence-Based Physical Activity Recommendations for Adults (18-64 Years)","author":"Brown","year":"2013"},{"key":"B6","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1186\/s12966-021-01194-9","article-title":"Cross-sectional and prospective associations of sleep, sedentary and active behaviors with mental health in older people: a compositional data analysis from the Seniors-ENRICA-2 study","volume":"18","author":"Cabanas-S\u00e1nchez","year":"2021","journal-title":"Int. J. Behav. Nutr. Phys. Act."},{"key":"B7","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1093\/oxfordjournals.aje.a116074","article-title":"Physical activity and depression: evidence from the Alameda County study","volume":"134","author":"Camacho","year":"1991","journal-title":"Am. J. Epidemiol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"101424","DOI":"10.1016\/j.eclinm.2022.101424","article-title":"Associations of sedentary time and physical activity with adverse health conditions: outcome-wide analyses using isotemporal substitution model","volume":"48","author":"Cao","year":"2022","journal-title":"EClinicalMedicine"},{"key":"B9","doi-asserted-by":"publisher","first-page":"e0139984","DOI":"10.1371\/journal.pone.0139984","article-title":"Combined effects of time spent in physical activity, sedentary behaviors and sleep on obesity and cardio-metabolic health markers: a novel compositional data analysis approach","volume":"10","author":"Chastin","year":"","journal-title":"PLoS ONE"},{"key":"B10","doi-asserted-by":"publisher","first-page":"1800","DOI":"10.1002\/oby.21180","article-title":"Meta-analysis of the relationship between breaks in sedentary behavior and cardiometabolic health","volume":"23","author":"Chastin","year":"","journal-title":"Obesity"},{"key":"B11","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1016\/S2215-0366(18)30227-X","article-title":"Association between physical exercise and mental health in 1\u00b72 million individuals in the USA between 2011 and 2015: a cross-sectional study","volume":"5","author":"Chekroud","year":"2018","journal-title":"Lancet Psychiatry"},{"key":"B12","doi-asserted-by":"publisher","first-page":"pzac002","DOI":"10.1093\/ptj\/pzac002","article-title":"Isotemporal substitution of sedentary behavior with moderate to vigorous physical activity is associated with lower risk of disability: a prospective longitudinal cohort study","volume":"102","author":"Chiba","year":"2022","journal-title":"Physical Therapy"},{"key":"B13","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1186\/s44167-023-00024-6","article-title":"The association between 24-hour activity, sedentary and sleep compositions and mental health in Australian adults: a cross-sectional study","volume":"2","author":"Curtis","year":"2023","journal-title":"J. Activity Sedentary Sleep Behav."},{"key":"B14","doi-asserted-by":"publisher","first-page":"e0279401","DOI":"10.1371\/journal.pone.0279401","article-title":"Time-use movement behaviors are associated with scores of depression\/anxiety among adolescents: a compositional data analysis","volume":"17","author":"de Faria","year":"2022","journal-title":"PLoS ONE"},{"key":"B15","doi-asserted-by":"publisher","first-page":"e018978","DOI":"10.1136\/bmjopen-2017-018978","article-title":"Associations between physical behavior patterns and levels of depressive symptoms, anxiety and well-being in middle-aged adults: a cross-sectional study using isotemporal substitution models","volume":"8","author":"Dillon","year":"2018","journal-title":"BMJ open."},{"key":"B16","doi-asserted-by":"publisher","first-page":"926","DOI":"10.1136\/bjsports-2020-103140","article-title":"Customary physical activity and odds of depression: a systematic review and meta-analysis of 111 prospective cohort studies","volume":"55","author":"Dishman","year":"2021","journal-title":"Br. J. Sports Med."},{"key":"B17","doi-asserted-by":"publisher","first-page":"846","DOI":"10.1177\/0962280217737805","article-title":"The compositional isotemporal substitution model: a method for estimating changes in a health outcome for reallocation of time between sleep, physical activity and sedentary behaviour","volume":"28","author":"Dorothea","year":"2017","journal-title":"Stat. Methods Med. Res."},{"key":"B18","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ"},{"key":"B19","doi-asserted-by":"publisher","first-page":"251","DOI":"10.4324\/9781003026426-16","author":"Fairclough","year":"2020"},{"key":"B20","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1016\/j.tins.2019.07.002","article-title":"Anxiety and brain mitochondria: a bidirectional crosstalk","volume":"42","author":"Filiou","year":"2019","journal-title":"Trends Neurosci."},{"key":"B21","doi-asserted-by":"publisher","first-page":"100380","DOI":"10.1016\/j.mhpa.2020.100380","article-title":"Effects of reallocating physical activity, sedentary behaviors, and sleep on mental health in adolescents","volume":"20","author":"Gilchrist","year":"2021","journal-title":"Ment. Health Phys. Act."},{"key":"B22","doi-asserted-by":"publisher","first-page":"1672","DOI":"10.1097\/00005768-199812000-00003","article-title":"Gender effect on beta-endorphin response to exercise","volume":"30","author":"Goldfarb","year":"1998","journal-title":"Med. Sci. Sports Exerc."},{"key":"B23","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1186\/s12966-018-0691-3","article-title":"Health outcomes associated with reallocations of time between sleep, sedentary behavior, and physical activity: a systematic scoping review of isotemporal substitution studies","volume":"15","author":"Grgic","year":"2018","journal-title":"Int. J. Behav. Nutr. Phys. Act"},{"key":"B24","doi-asserted-by":"publisher","first-page":"e29917","DOI":"10.1097\/MD.0000000000029917","article-title":"Leisure-time physical activity and risk of depression: a dose-response meta-analysis of prospective cohort studies","volume":"101","author":"Guo","year":"2022","journal-title":"Medicine"},{"key":"B25","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1192\/bjp.2019.60","article-title":"Cross-sectional and prospective relationships of passive and mentally active sedentary behaviors and physical activity with depression","volume":"217","author":"Hallgren","year":"2020","journal-title":"Br. J. Psychiatry"},{"key":"B26","first-page":"619","article-title":"A likelihood approach to meta-analysis with random effects. Stat","volume":"15","author":"Hardy","year":"1996","journal-title":"Med"},{"key":"B27","doi-asserted-by":"crossref","DOI":"10.1002\/9781119536604","volume-title":"Cochrane Handbook for Systematic Reviews of Interventions.","author":"Higgins","year":"2019"},{"key":"B28","doi-asserted-by":"publisher","first-page":"1539","DOI":"10.1002\/sim.1186","article-title":"Quantifying heterogeneity in a meta-analysis","volume":"21","author":"Higgins","year":"2002","journal-title":"Stat. Med."},{"key":"B29","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1136\/jech-2020-215883","article-title":"Substitutions of physical activity, sedentary behaviour and sleep: associations with mental health in middle-aged and elderly persons","volume":"76","author":"Hofman","year":"2022","journal-title":"J. Epidemiol. Community Health"},{"key":"B30","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1016\/j.jad.2021.12.064","article-title":"Impact on adolescent mental health of replacing screen-use with exercise: a prospective cohort study","volume":"301","author":"Kandola","year":"2022","journal-title":"BMJ Open."},{"key":"B31","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1146\/annurev-publhealth-031912-114409","article-title":"The epidemiology of depression across cultures","volume":"34","author":"Kessler","year":"2013","journal-title":"Annu. Rev. Public Health."},{"key":"B32","doi-asserted-by":"publisher","first-page":"1490","DOI":"10.3109\/09638288.2014.972579","article-title":"Exercise therapy improves both mental and physical health in patients with major depression","volume":"37","author":"Knapen","year":"2015","journal-title":"Disabil. Rehabil."},{"key":"B33","doi-asserted-by":"publisher","first-page":"718789","DOI":"10.5402\/2012\/718789","article-title":"Physical activity, health benefits, and mortality risk","volume":"2012","author":"Kokkinos","year":"2012","journal-title":"ISRN Cardiol."},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD004691.pub2","article-title":"Exercise in prevention and treatment of anxiety and depression among children and young people","author":"Larun","year":"2006","journal-title":"Cochrane Database Syst. Rev."},{"key":"B35","doi-asserted-by":"publisher","first-page":"2241","DOI":"10.1186\/s12889-023-17134-0","article-title":"Correlation analysis between physical activity and depressive tendencies among occupational groups: an isotemporal substitution approach","volume":"23","author":"Liu","year":"2023","journal-title":"BMC Public Health."},{"key":"B36","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1016\/j.amepre.2013.08.001","article-title":"Physical activity and the prevention of depression: a systematic review of prospective studies","volume":"45","author":"Mammen","year":"2013","journal-title":"Am. J. Prev. Med."},{"key":"B37","doi-asserted-by":"publisher","first-page":"e442","DOI":"10.1371\/journal.pmed.0030442","article-title":"Projections of global mortality and burden of disease from 2002 to 2030","volume":"3","author":"Mathers","year":"2006","journal-title":"PLoS Med."},{"key":"B38","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1093\/aje\/kws590","article-title":"Isotemporal substitution analysis for physical activity, television watching, and risk of depression","volume":"178","author":"Mekary","year":"2013","journal-title":"Am. J. Epidemiol."},{"key":"B39","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1093\/aje\/kwp163","article-title":"Isotemporal substitution paradigm for physical activity epidemiology and weight change","volume":"170","author":"Mekary","year":"2009","journal-title":"Am. J. Epidemiol."},{"key":"B40","doi-asserted-by":"publisher","first-page":"e2023144","DOI":"10.1590\/1516-3180.2023.0144.r2.04122023","article-title":"Isotemporal substitution analysis of time between sleep, sedentary behavior, and physical activity on depressive symptoms in older adults: a cross-sectional study","volume":"142","author":"Meneguci","year":"2024","journal-title":"Sao Paulo Med. J."},{"key":"B41","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1016\/j.jad.2017.09.022","article-title":"Diet quality and depression risk: a systematic review and dose-response meta-analysis of prospective studies","volume":"226","author":"Molendijk","year":"2018","journal-title":"J. Affect. Disord."},{"key":"B42","doi-asserted-by":"publisher","first-page":"1290","DOI":"10.1080\/02640414.2023.2268359","article-title":"Observational longitudinal association between waking movement behaviors and psychological distress among adolescents using isotemporal analysis: DADOS study","volume":"41","author":"Monteagudo","year":"2023","journal-title":"J. Sports Sci."},{"key":"B43","doi-asserted-by":"publisher","first-page":"2236","DOI":"10.1186\/s12889-023-17117-1","article-title":"Association between depression, anemia and physical activity using isotemporal substitution analysis","volume":"23","author":"Nam","year":"2023","journal-title":"BMC Public Health"},{"key":"B44","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.jclinepi.2021.02.003","article-title":"Updating guidance for reporting systematic reviews: development of the PRISMA 2020 statement","volume":"134","author":"Page","year":"2021","journal-title":"J. Clin. Epidemiol."},{"key":"B45","doi-asserted-by":"publisher","first-page":"e078199","DOI":"10.1136\/bmjopen-2023-078199","article-title":"Association between accelerometer-derived physical activity and depression: a cross-sectional study using isotemporal substitution analysis","volume":"14","author":"Park","year":"2024","journal-title":"BMJ Open"},{"key":"B46","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1001\/jamapsychiatry.2022.0609","article-title":"Association between physical activity and risk of depression: a systematic review and meta-analysis","volume":"79","author":"Pearce","year":"2022","journal-title":"JAMA Psychiatry"},{"key":"B47","doi-asserted-by":"publisher","first-page":"e005263","DOI":"10.1161\/CIRCOUTCOMES.118.005263","article-title":"Physical activity guidelines for Americans from the US department of health and human services: cardiovascular benefits and recommendations","volume":"11","author":"Piercy","year":"2018","journal-title":"Circ. Cardiovasc. Qual. Outcomes."},{"key":"B48","doi-asserted-by":"publisher","first-page":"19","DOI":"10.2165\/00007256-200636010-00003","article-title":"A review of physical activity patterns in pregnant women and their relationship to psychological health","volume":"36","author":"Poudevigne","year":"2006","journal-title":"Sports Med."},{"key":"B49","doi-asserted-by":"publisher","first-page":"733","DOI":"10.1123\/jpah.2016-0648","article-title":"Isotemporal analysis of the association of objectively measured physical activity with depressive symptoms: results from hispanic community health study\/study of latinos (HCHS\/SOL)","volume":"14","author":"Rethorst","year":"2017","journal-title":"J. Phys. Act. Health."},{"key":"B50","doi-asserted-by":"publisher","first-page":"102605","DOI":"10.1016\/j.psychsport.2024.102605","article-title":"Substitutions of physical activity and sedentary behavior with negative emotions and sex difference among college students","volume":"72","author":"Rong","year":"2024","journal-title":"Psychol. Sport Exerc."},{"key":"B51","doi-asserted-by":"publisher","first-page":"14465","DOI":"10.4088\/JCP.13r08765","article-title":"Physical activity interventions for people with mental illness: a systematic review and meta-analysis","volume":"75","author":"Rosenbaum","year":"2014","journal-title":"J. Clin. Psychiatry"},{"key":"B52","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/j.jsams.2023.04.007","article-title":"Exchanging screen for non-screen sitting time or physical activity might attenuate depression and anxiety: a cross-sectional isotemporal analysis during early pandemics in South America","volume":"26","author":"Sadarangani","year":"2023","journal-title":"J. Sci. Med. Sport"},{"key":"B53","doi-asserted-by":"publisher","first-page":"e0256867","DOI":"10.1371\/journal.pone.0256867","article-title":"Longitudinal association between movement behaviors and depressive symptoms among adolescents using compositional data analysis","volume":"16","author":"Sampasa-Kanyinga","year":"2021","journal-title":"PLoS ONE"},{"key":"B54","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1176\/appi.ajp.2018.17111194","article-title":"Physical activity and incident depression: a meta-analysis of prospective cohort studies","volume":"175","author":"Schuch","year":"2018","journal-title":"Am. J. Psychiatry"},{"key":"B55","doi-asserted-by":"publisher","first-page":"1206","DOI":"10.1136\/bjsports-2017-098270","article-title":"Effectiveness of interventions for reducing non-occupational sedentary behavior in adults and older adults: a systematic review and meta-analysis","volume":"53","author":"Shrestha","year":"2019","journal-title":"Br. J. Sports Med."},{"key":"B56","doi-asserted-by":"publisher","first-page":"1203","DOI":"10.1136\/bjsports-2022-106195","article-title":"Effectiveness of physical activity interventions for improving depression, anxiety and distress: an overview of systematic reviews","volume":"57","author":"Singh","year":"2023","journal-title":"Br. J. Sports Med."},{"key":"B57","first-page":"159","article-title":"A cross-sectional study on the relationship between 24-hour activities and depressive symptoms in vocational school students","volume":"51","author":"Tang","year":"2024","journal-title":"Fudan Univ. J. Med. Sci."},{"key":"B58","doi-asserted-by":"publisher","first-page":"1093","DOI":"10.1001\/jamapediatrics.2014.1794","article-title":"Exercise and depressive symptoms in adolescents: a longitudinal cohort study","volume":"168","author":"Toseeb","year":"2014","journal-title":"JAMA pediatr."},{"key":"B59","doi-asserted-by":"publisher","first-page":"S311","DOI":"10.1139\/apnm-2016-0203","article-title":"Canadian 24-hour movement guidelines for children and youth: an integration of physical activity, sedentary behavior, and sleep","volume":"41","author":"Tremblay","year":"2016","journal-title":"Appl. Physiol. Nutr. Metab."},{"key":"B60","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1139\/H10-079","article-title":"Physiological and health implications of a sedentary lifestyle","volume":"35","author":"Tremblay","year":"2010","journal-title":"Appl. Physiol. Nutr. Metab."},{"key":"B61","doi-asserted-by":"publisher","first-page":"1957","DOI":"10.1111\/sms.13762","article-title":"Sedentary behavior, physical activity, and mental health in older adults: An isotemporal substitution model","volume":"30","author":"Tully","year":"2020","journal-title":"Scand. J. Med. Sci. Sports."},{"key":"B62","doi-asserted-by":"publisher","first-page":"1545","DOI":"10.1016\/S0140-6736(16)31678-6","article-title":"Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990\u20132015: a systematic analysis for the global burden of disease study 2015","volume":"388","author":"Vos","year":"2016","journal-title":"Lancet"},{"key":"B63","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12966-018-0661-9","article-title":"The 2017 Dutch physical activity guidelines","volume":"15","author":"Weggemans","year":"2018","journal-title":"Int. J. Behav. Nutr. Phys. Act."},{"key":"B64","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1016\/j.jad.2019.07.036","article-title":"Isotemporal substitution modeling on sedentary behaviors and physical activity with depressive symptoms among older adults in the U.S.: the national health and nutrition examination survey, 2007\u20132016","volume":"257","author":"Wei","year":"2019","journal-title":"J. Affect Disord."},{"key":"B65","unstructured":"Wells\n              G. A.\n            \n            \n              Shea\n              B.\n            \n            \n              O'Connell\n              D.\n            \n            \n              Peterson\n              J.\n            \n            \n              Welch\n              V.\n            \n            \n              Losos\n              M.\n            \n          \n          The Newcastle-Ottawa Scale (NOS) for Assessing the Quality of Nonrandomized Studies in Meta-analysis\n          \n          2000"},{"key":"B66","doi-asserted-by":"publisher","first-page":"776","DOI":"10.1136\/bjsports-2018-100168","article-title":"Distinct effects of acute exercise and breaks in sitting on working memory and executive function in older adults: a three-arm, randomised cross-over trial to evaluate the effects of exercise with and without breaks in sitting on cognition","volume":"54","author":"Wheeler","year":"2020","journal-title":"Br. J. Sports Med."},{"key":"B67","unstructured":"Depression and Other Common Mental Disorders: Global Health Estimates\n          \n          2017"},{"key":"B68","unstructured":"Global Recommendations on Physical Activity for Health\n          \n          2020"},{"key":"B69","doi-asserted-by":"publisher","first-page":"e022282","DOI":"10.1136\/bmjopen-2018-022282","article-title":"Cross-sectional associations of sedentary behavior and physical activity on depression in Japanese older adults: an isotemporal substitution approach","volume":"8","author":"Yasunaga","year":"2018","journal-title":"BMJ Open"},{"key":"B70","doi-asserted-by":"publisher","first-page":"652","DOI":"10.1016\/j.jad.2022.12.098","article-title":"Dose-response association of total sedentary behavior and television watching with risk of depression in adults: a systematic review and meta-analysis","volume":"324","author":"Zhou","year":"2023","journal-title":"J Affect Disord."},{"key":"B71","doi-asserted-by":"publisher","first-page":"1388","DOI":"10.1186\/s12889-024-18914-y","article-title":"The effect of replacing sedentary behavior with different intensities of physical activity on depression and anxiety in Chinese university students: an isotemporal substitution model","volume":"24","author":"Zhou","year":"2024","journal-title":"BMC Public Health"},{"key":"B72","doi-asserted-by":"publisher","first-page":"2105","DOI":"10.1007\/s00127-024-02708-z","article-title":"Replacement of sedentary behavior with various physical activities and the risk of incident depression: a prospective analysis of accelerator-measured and self-reported UK Biobank data","volume":"59","author":"Zhu","year":"2024","journal-title":"Soc. Psychiatry Psychiatr. Epidemiol"}],"container-title":["Frontiers in Psychology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpsyg.2025.1505061\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T05:39:08Z","timestamp":1745991548000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpsyg.2025.1505061\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,30]]},"references-count":72,"alternative-id":["10.3389\/fpsyg.2025.1505061"],"URL":"https:\/\/doi.org\/10.3389\/fpsyg.2025.1505061","relation":{},"ISSN":["1664-1078"],"issn-type":[{"value":"1664-1078","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,30]]},"article-number":"1505061"}}