{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T01:35:40Z","timestamp":1790472940484,"version":"4.1.0"},"reference-count":57,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T00:00:00Z","timestamp":1759968000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100009931","name":"Michigan Department of Health and Human Services","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009931","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009931","name":"Michigan Department of Health and Human Services","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009931","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011822","name":"Michigan Health Endowment Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011822","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007270","name":"University of Michigan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007270","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychol."],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>This study evaluates the impact of a home-based infant mental health intervention on maternal mental health symptoms. Prevalence rates of maternal depression, anxiety and trauma symptoms are quite high during the postpartum period and can contribute to ruptures in the parent\u2013child relationship and infant development. While some infant mental health interventions improve depression, less is known about the impact of home-based or attachment-based psychotherapeutic interventions on maternal anxiety or post traumatic stress disorder.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Using a randomized controlled trial design, mothers with infants were recruited and randomized to infant mental health home visiting (IMH-HV; <jats:italic>n<\/jats:italic>\u202f=\u202f38) or a control group (<jats:italic>n<\/jats:italic>\u202f=\u202f35). However, five dyads who were assigned to the treatment group but received no treatment were omitted from the analysis, for a per-protocol analysis of 68 mothers. Mothers reported on their depression (Patient Health Questionnaire, PHQ-9), anxiety (General Anxiety Disorder, GAD-7), and trauma symptoms (PTSD Checklist, PCL-5) at baseline, and six and 12\u202fmonths later.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mothers in the per-protocol treatment group (<jats:italic>n<\/jats:italic>\u202f=\u202f33) demonstrated greater decreases in mental health symptoms over the 12\u202fmonths of the study than those in the control group (<jats:italic>n<\/jats:italic>\u202f=\u202f35) (slope effects: for depression (\u22120.19, <jats:italic>p<\/jats:italic>\u202f=\u202f0.015), anxiety (\u22120.13, <jats:italic>p<\/jats:italic>\u202f=\u202f0.058), and trauma (\u22120.46, <jats:italic>p<\/jats:italic>\u202f=\u202f0.057)).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Results suggest that IMH-HV services are effective in reducing mental health symptoms for mothers who actually received treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical trial registration<\/jats:title><jats:p>NCT03175796<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpsyg.2025.1597655","type":"journal-article","created":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T04:22:16Z","timestamp":1759983736000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Improved mental health for women receiving infant mental health home visiting: a randomized controlled trial"],"prefix":"10.3389","volume":"16","author":[{"given":"Jennifer M.","family":"Jester","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann M.","family":"Stacks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica L.","family":"Riggs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holly E.","family":"Brophy-Herb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Muzik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Rosenblum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Michigan Collaborative for Infant Mental Health Research","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,10,9]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1016\/j.beth.2013.01.002","article-title":"A clinical trial of in-home CBT for depressed mothers in home visitation","volume":"44","author":"Ammerman","year":"2013","journal-title":"Behav. 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Health J."},{"key":"ref9002","doi-asserted-by":"publisher","first-page":"575","DOI":"10.15585\/mmwr.mm6919a2","article-title":"Vital Signs: Postpartum Depressive Symptoms and Provider Discussions About Perinatal Depression \u2014 United States, 2018","volume":"69","author":"Bauman","year":"2020","journal-title":"MMWR Morbidity Mortality Weekly Report"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1111\/j.1523-536X.2011.00475.x","article-title":"Posttraumatic stress disorder in new mothers: results from a two-stage U.S. national survey","volume":"38","author":"Beck","year":"2011","journal-title":"Birth"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1159\/000447597","article-title":"Postnatal mother-to-infant attachment in subclinically depressed mothers: dyads at risk?","volume":"49","author":"Behrendt","year":"2016","journal-title":"Psychopathology"},{"key":"ref9003","first-page":"1","article-title":"Depression prevalence in adolescents and adults: United States, August 2021\u2013August 2023","author":"Brody","year":"2025"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1002\/imhj.20127","article-title":"It takes time: impacts of early head start that lead to reductions in maternal depression two years later","volume":"28","author":"Chazan-Cohen","year":"2007","journal-title":"Infant Ment. Health J."},{"key":"ref11","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1186\/s12887-025-05580","volume":"25","author":"Cibralic","year":"2025","journal-title":"BMC Pediatr."},{"key":"ref12","doi-asserted-by":"publisher","first-page":"919","DOI":"10.1097\/CHI.0b013e3181b21651","article-title":"Maternal depression and anxiety across the postpartum year and infant social engagement, fear regulation, and stress reactivity","volume":"48","author":"Feldman","year":"2009","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"key":"ref13","author":"Folger","year":"2022"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1002\/imhj.21553","article-title":"Randomized controlled trial of parent\u2013infant psychotherapy for parents with mental health problems and young infants","volume":"37","author":"Fonagy","year":"2016","journal-title":"Infant Ment. 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Psychol."},{"key":"ref37","doi-asserted-by":"publisher","first-page":"e227","DOI":"10.1097\/DBP.0000000000001020","article-title":"Infant mental health home visiting mitigates impact of maternal adverse childhood experiences on toddler language competence: a randomized controlled trial","volume":"43","author":"Riggs","year":"2022","journal-title":"J. Dev. Behav. Pediatr."},{"key":"ref38","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1002\/imhj.21840","article-title":"Community-delivered infant\u2013parent psychotherapy improves maternal sensitive caregiving: evaluation of the Michigan model of infant mental health home visiting","volume":"41","author":"Rosenblum","year":"2020","journal-title":"Infant Ment. Health J."},{"key":"ref39","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1002\/imhj.21406","article-title":"Minding the baby: enhancing reflectiveness to improve early health and relationship outcomes in an interdisciplinary home-visiting program","volume":"34","author":"Sadler","year":"2013","journal-title":"Infant Ment. Health J."},{"key":"ref40","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1111\/j.1467-8624.1993.tb02896.x","article-title":"Stability of intelligence from preschool to adolescence: the influence of social and family risk factors","volume":"64","author":"Sameroff","year":"1993","journal-title":"Child Dev."},{"key":"ref41","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1093\/schbul\/13.3.383","article-title":"Early indicators of developmental risk: the Rochester longitudinal study","volume":"13","author":"Sameroff","year":"1987","journal-title":"Schizophr. Bull."},{"key":"ref42","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1016\/j.jhealeco.2018.02.008","article-title":"Evaluating the effects of a targeted home visiting program on maternal and child health outcomes","volume":"58","author":"Sandner","year":"2018","journal-title":"J. Health Econ."},{"key":"ref43","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1016\/j.infbeh.2013.03.009","article-title":"Subclinical levels of maternal depression and infant sensitivity to social contingency","volume":"36","author":"Skotheim","year":"2013","journal-title":"Infant Behav. Dev."},{"key":"ref44","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1017\/S0954579419001463","article-title":"Minding the baby\u00ae: enhancing parental reflective functioning and infant attachment in an attachment-based, interdisciplinary home visiting program","volume":"32","author":"Slade","year":"2020","journal-title":"Dev. Psychopathol."},{"key":"ref45","doi-asserted-by":"publisher","first-page":"1745506519844044","DOI":"10.1177\/1745506519844044","article-title":"Consequences of maternal postpartum depression: a systematic review of maternal and infant outcomes","volume":"15","author":"Slomian","year":"2019","journal-title":"Womens Health"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"1092","DOI":"10.1001\/archinte.166.10.1092","article-title":"A brief measure for assessing generalized anxiety disorder the GAD-7","volume":"166","author":"Spitzer","year":"2006","journal-title":"Arch. Intern. Med."},{"key":"ref47","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1002\/imhj.21785","article-title":"Infant mental health home visiting in the context of an infant-toddler court team: changes in parental responsiveness and reflective functioning","volume":"40","author":"Stacks","year":"2019","journal-title":"Infant Ment. Health J."},{"key":"ref48","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1080\/14616734.2020.1865606","article-title":"Infant mental health home visiting: intervention dosage and therapist experience interact to support improvements in maternal reflective functioning","volume":"24","author":"Stacks","year":"2022","journal-title":"Attach Hum. 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