{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T11:23:43Z","timestamp":1768217023211,"version":"3.49.0"},"reference-count":29,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T00:00:00Z","timestamp":1768176000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychol."],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Uterus transplantation represents a revolutionary breakthrough for women with absolute infertility of uterine origin, offering them the possibility of realizing the dream of motherhood. This complex procedure has profound medical, ethical, and psychological implications. The aim of our study was to assess the personality, the presence of anxiety and depression, and perceived quality of life in a 29-year-old woman affected by Rokitansky syndrome (MRKH). Furthermore, we hypothesized that projective tests, compared with quantitative assessments, could more easily uncover the deepest, unconscious psychic contents of this woman who has faced such a difficult journey.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Descriptive Longitudinal Study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects<\/jats:title>\n                    <jats:p>Single case.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main outcome measures<\/jats:title>\n                    <jats:p>The case report follows the Case Reporting (CARE) guidelines. In the pre-transplant evaluation, Giorgia (not her real name) was administered the Machover Test, the Baum Test, the Million Clinical Multiaxial Inventory- III (MCMI-III), the Short Form Health Survey-36 (F-36), the Patient Health Questionnaire-9 (PHQ-9), and the General Anxiety Disorder-7 (GAD-7). The same instruments were re-administered 1\u2009year and 2\u2009years after the birth of her baby girl.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The projective graphic tests highlighted some significant aspects: the facial expression of the female figure became more restless in subsequent evaluations, until aggressiveness emerged (clenched fists) in the last evaluation. The tree was also drawn on a flowerbed in the last evaluations, indicating a sense of loneliness and abandonment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Overall, uterus transplantation appears to be psychologically well-tolerated, but ongoing evaluation and psychological support are essential.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpsyg.2025.1713821","type":"journal-article","created":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T08:12:07Z","timestamp":1768205527000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case Report: From absolute uterine factor infertility (AUI) to motherhood: the crucial role of psychosocial assessment in the first Italian uterus transplantation case"],"prefix":"10.3389","volume":"16","author":[{"given":"Maria Luisa","family":"Pistorio","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Concetta","family":"De Pasquale","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimiliano","family":"Veroux","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessia","family":"Giaquinta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina Maria","family":"Giambra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonino","family":"Grasso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Scollo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Catena Ausilia","family":"Quattropani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierfrancesco","family":"Veroux","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,1,12]]},"reference":[{"key":"ref1","volume-title":"Diagnostic and Statistical Manual of Mental Disorders: DSM-5","year":"2013"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1016\/j.rbmo.2022.01.015","article-title":"Tailored support may reduce mental and relational impact of infertility on infertile patients and partners","volume":"44","author":"Boivin","year":"2022","journal-title":"Reprod. Biomed. Online"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1097\/MOT.0000000000000936","article-title":"Uterus transplantation worldwide: clinical activities and outcomes","volume":"26","author":"Br\u00e4nnstr\u00f6m","year":"2021","journal-title":"Curr. Opin. Organ Transplant."},{"key":"ref4","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/j.jogoh.2018.03.006","article-title":"Uterine transplantation: review in human research","volume":"47","author":"Favre-Inhofer","year":"2018","journal-title":"J. Gynecol. Obstet. Hum. Reprod."},{"key":"ref5","doi-asserted-by":"publisher","first-page":"381","DOI":"10.3109\/19390211.2013.830679","article-title":"The CARE guidelines: consensus-based clinical case report guideline development","volume":"10","author":"Gagnier","year":"2013","journal-title":"J. Diet. Suppl."},{"key":"ref6","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1111\/aogs.14974.","article-title":"Psychological and emotional profiles of Australian uterine transplant potential recipients: a comparison with international trials","volume":"104","author":"Gerstl","year":"2025","journal-title":"Acta Obstet. Gynecol. Scand."},{"key":"ref7","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1002\/nop2.1062","article-title":"A qualitative study of the factors that help the coping of infertile women","volume":"9","author":"Halkola","year":"2022","journal-title":"Nurs. Open"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1093\/humrep\/deab260","article-title":"Striving for motherhood after uterus transplantation: a qualitative study concerning pregnancy attempts, and the first years of parenthood after transplantation","volume":"37","author":"J\u00e4rvholm","year":"2021","journal-title":"Hum. Reprod."},{"key":"ref9","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1016\/j.fertnstert.2020.03.043","article-title":"Psychosocial outcomes of uterine transplant recipients and partners up to 3 years after transplantation: results from the Swedish trial","volume":"114","author":"J\u00e4rvholm","year":"2020","journal-title":"Fertil. Steril."},{"key":"ref10","doi-asserted-by":"publisher","first-page":"1010","DOI":"10.1016\/j.fertnstert.2015.06.038","article-title":"Uterus transplantation trial: psychological evaluation of recipients and partners during the post-transplantation year","volume":"104","author":"J\u00e4rvholm","year":"2015","journal-title":"Fertil. Steril."},{"key":"ref11","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1093\/humrep\/dead245","article-title":"Long-term health-related quality-of-life and psychosocial outcomes after uterus transplantation: a 5-year follow-up of donors and recipients","volume":"39","author":"J\u00e4rvholm","year":"2024","journal-title":"Hum. Reprod."},{"key":"ref12","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1097\/GRF.0000000000000673","article-title":"Uterus transplantation: lessons learned from a psychological perspective","volume":"65","author":"J\u00e4rvholm","year":"2022","journal-title":"Clin. Obstet. Gynecol."},{"key":"ref13","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1097\/AOG.0000000000004244","article-title":"Twelve live births after uterus transplantation in the Dallas UtErus transplant study","volume":"137","author":"Johannesson","year":"2021","journal-title":"Obstet. Gynecol."},{"key":"ref14","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1111\/aogs.15004","article-title":"Psychological evaluation of candidates for the uterus transplantation French trial","volume":"104","author":"Karpel","year":"2025","journal-title":"Acta Obstet. Gynecol. Scand."},{"key":"ref15","volume-title":"Patient Health Questionnaire-9 (PHQ-9)","author":"Kroenke","year":"1999"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"292","DOI":"10.5964\/ejop.v15i2.1736","article-title":"Extreme desire for motherhood: analysis of narratives from women undergoing assisted reproductive technology (ART)","volume":"15","author":"Langher","year":"2019","journal-title":"Eur. J. Psychol."},{"key":"ref17","doi-asserted-by":"publisher","first-page":"205031211667172","DOI":"10.1177\/2050312116671725","article-title":"SF-36 total score as a single measure of health-related quality of life: scoping review","volume":"4","author":"Lins","year":"2016","journal-title":"SAGE Open Med."},{"key":"ref18","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1080\/09513590.2018.1540575","article-title":"Impact of infertility and infertility treatments on quality of life and levels of anxiety and depression in women undergoing in vitro fertilization","volume":"35","author":"Massarotti","year":"2019","journal-title":"Gynecol. Endocrinol."},{"key":"ref19","volume-title":"MCMI-III Millon Clinical Multiaxial Inventory-III","author":"Millon","year":"2008"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1186\/s12955-017-0712-y","article-title":"Quality of life and general health of infertile women","volume":"15","author":"Namdar","year":"2017","journal-title":"Health Qual. Life Outcomes"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1111\/jog.15825","article-title":"Miracles of science: birth after uterus transplantation","volume":"50","author":"Ongun","year":"2024","journal-title":"J. Obstet. Gynaecol. Res."},{"key":"ref22","volume-title":"Metodi e tecniche nella diagnosi della personalit\u00e0","author":"Passi Tognazzo","year":"1977"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1111\/ajo.13114","article-title":"Uterus transplantation: perspectives of Australian women with absolute uterine factor infertility regarding desirability and utility","volume":"60","author":"Pittman","year":"2020","journal-title":"Aust. N. Z. J. Obstet. Gynaecol."},{"key":"ref24","doi-asserted-by":"publisher","first-page":"378","DOI":"10.5935\/1518-0557.20250002","article-title":"Psychosocial aspects of infertility and the impact of assisted reproductive techniques - a comprehensive review","volume":"29","author":"Ribeiro Neto","year":"2025","journal-title":"JBRA Assist. Reprod."},{"key":"ref25","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1080\/23294515.2019.1572672","article-title":"Framing the diagnosis and treatment of absolute uterine factor infertility: insights from in-depth interviews with uterus transplant trial participants","volume":"10","author":"Richards","year":"2019","journal-title":"AJOB Empir. Bioeth."},{"key":"ref26","first-page":"86","article-title":"Disability, psychiatric symptoms, and quality of life in infertile women: a cross-sectional study in Turkey","volume":"28","author":"Sezgin","year":"2016","journal-title":"Shanghai Arch. Psychiatry"},{"key":"ref27","volume-title":"Generalized Anxiety Disorder 7 (GAD-7)","author":"Spitzer","year":"2006"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"6821","DOI":"10.3390\/jcm13226821","article-title":"Uterus transplantation from deceased donors: first Italian experience","volume":"13","author":"Veroux","year":"2024","journal-title":"J. Clin. Med."},{"key":"ref29","doi-asserted-by":"publisher","first-page":"1095","DOI":"10.1111\/1471-0528.17052","article-title":"The journey from infertility to uterus transplantation: a qualitative study of the perspectives of participants in the Dallas uterus transplant study","volume":"129","author":"Wall","year":"2021","journal-title":"BJOG"}],"container-title":["Frontiers in Psychology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpsyg.2025.1713821\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T08:12:13Z","timestamp":1768205533000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpsyg.2025.1713821\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,12]]},"references-count":29,"alternative-id":["10.3389\/fpsyg.2025.1713821"],"URL":"https:\/\/doi.org\/10.3389\/fpsyg.2025.1713821","relation":{},"ISSN":["1664-1078"],"issn-type":[{"value":"1664-1078","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,12]]},"article-number":"1713821"}}