{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T14:40:58Z","timestamp":1790347258750,"version":"4.1.0"},"reference-count":62,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T00:00:00Z","timestamp":1768867200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychol."],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Although a health-promoting lifestyle is associated with greater well-being among university students, the psychological (anxiety, depression) and physiological (sleep quality) mechanisms underlying this relationship remain insufficiently established, highlighting the need for integrative models that better explain well-being. Moreover, empirical evidence on these relationships is still limited in lower\u2013middle-income countries. Accordingly, this study tested a model in which a health-promoting lifestyle predicts subjective well-being, with depression, anxiety, and sleep quality serving as mediating variables within a Latin American context.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>A cross-sectional design was employed with a sample of 6,704 Honduran university students. The instruments included a short version of the Health-Promoting Lifestyle Profile II (HPLP-II), the Patient Health Questionnaire-9 (PHQ-9), the Generalized Anxiety Disorder 7-item Scale (GAD-7), the Single-Item Sleep Quality Scale (SQS), and the World Health Organization Well-Being Index (WHO-5). Measurement models for each instrument and a multiple-mediation structural equation model were estimated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The final structural model demonstrated adequate fit and explained 61.6% of the variance in well-being. A health-promoting lifestyle predicted greater well-being both directly and indirectly. Among the mediators, depression and sleep quality showed significant indirect effects, whereas anxiety did not play a statistically significant mediating role. Overall, the findings confirm that a health-promoting lifestyle is associated with lower depressive symptomatology and better sleep quality, which in turn enhances subjective well-being.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The findings support an integrative model in which a health-promoting lifestyle explains student well-being, highlighting depression and sleep quality as key pathways of influence. These results broaden the understanding of well-being from a multidimensional perspective and provide actionable evidence for designing institutional policies and intervention strategies that promote healthy lifestyle behaviors and well-being, particularly in Latin American settings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpsyg.2025.1735602","type":"journal-article","created":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T06:29:34Z","timestamp":1768890574000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Health-promoting lifestyle as a predictor of well-being in Honduran university students: a structural equation modeling approach with mental health and sleep quality as mediators"],"prefix":"10.3389","volume":"16","author":[{"given":"Marcio Alexander","family":"Castillo-D\u00edaz","sequence":"first","affiliation":[{"name":"Graduate Program in Psychometrics and Educational Evaluation, Department of Psychology, Faculty of Social Sciences, Universidad Nacional Aut\u00f3noma de Honduras","place":["Tegucigalpa, Honduras"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos Alberto Henao","family":"Peria\u00f1ez","sequence":"additional","affiliation":[{"name":"School of Nursing, Faculty of Health, Universidad del Valle","place":["Cali, Colombia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,1,20]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"154","DOI":"10.3390\/healthcare12020154","article-title":"Factors associated with lifestyle behaviors among university students\u2014a cross-sectional study","volume":"12","author":"Alothman","year":"2024","journal-title":"Healthcare"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"221","DOI":"10.24171\/j.phrp.2019.10.4.04","article-title":"The relationship between health-promoting lifestyle and its related factors with self-efficacy and well-being of students","volume":"10","author":"Amiri","year":"2019","journal-title":"Osong. Public Health Res. Perspect."},{"key":"ref3","doi-asserted-by":"publisher","first-page":"239","DOI":"10.4103\/jehp.jehp_963_22","article-title":"Health-promoting lifestyle and its determining factors among students of public and private universities in Iran","volume":"12","author":"Amiri","year":"2023","journal-title":"J. Educ. Health Promot."},{"key":"ref4","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1037\/abn0000362","article-title":"WHO world mental health surveys international college student project: prevalence and distribution of mental disorders","volume":"127","author":"Auerbach","year":"2018","journal-title":"J. Abnorm. Psychol."},{"key":"ref5","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1007\/s11325-024-03177-z","article-title":"Validation and cutoff score for the single-item sleep quality scale","volume":"29","author":"Badahdah","year":"2025","journal-title":"Sleep and Breath."},{"key":"ref6","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1186\/s40359-025-03041-z","article-title":"Longitudinal effects of stress in an academic context on psychological well-being, physiological markers, health behaviors, and academic performance in university students","volume":"13","author":"Ben\u00edtez-Agudelo","year":"2025","journal-title":"BMC Psychol."},{"key":"ref7","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1186\/1756-0500-3-267","article-title":"Structural equation modeling in medical research: a primer","volume":"3","author":"Beran","year":"2010","journal-title":"BMC. Res. Notes"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/S2215-0366(24)00254-2","article-title":"Estimating adolescent mental health in the general population: current challenges and opportunities","volume":"12","author":"Black","year":"2025","journal-title":"Lancet Psychiatry"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"931","DOI":"10.1080\/13548506.2021.1971724","article-title":"Sleep quantity and variability during the first semester at university: implications for well-being and academic performance","volume":"27","author":"Bono","year":"2022","journal-title":"Psychol. Health Med."},{"key":"ref10","doi-asserted-by":"publisher","first-page":"100022","DOI":"10.1016\/j.metip.2020.100022","article-title":"The quality of data collected online: an investigation of careless responding in a crowdsourced sample","volume":"2","author":"Br\u00fchlmann","year":"2020","journal-title":"Methods Psychol."},{"key":"ref11","doi-asserted-by":"publisher","first-page":"574","DOI":"10.1080\/17437199.2020.1760728","article-title":"Physical activity and subjective well-being in healthy individuals: a meta-analytic review","volume":"15","author":"Buecker","year":"2021","journal-title":"Health Psychol. Rev."},{"key":"ref12","doi-asserted-by":"publisher","first-page":"daae082","DOI":"10.1093\/heapro\/daae082","article-title":"Psychological distress, health-promoting lifestyle and sociodemographic factors in Honduran university students: a structural equation model","volume":"39","author":"Castillo-D\u00edaz","year":"2024","journal-title":"Health Promot. Int."},{"key":"ref13","doi-asserted-by":"publisher","first-page":"144","DOI":"10.5944\/reop.vol.33.num.3.2022.36466","article-title":"Alteraciones de salud mental y adaptaci\u00f3n universitaria en estudiantes Hondure\u00f1os: un an\u00e1lisis de grupos con rendimiento acad\u00e9mico diferenciado","volume":"33","author":"Castillo-D\u00edaz","year":"2022","journal-title":"Revista Espa\u00f1ola de Orientaci\u00f3n y Psicopedagog\u00eda"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-025-25899-9","article-title":"Psychometric validation and measurement invariance of the health-promoting lifestyle profile II in Honduran university students","author":"Castillo-D\u00edaz","year":"2025","journal-title":"BMC Public Health"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"e0297508","DOI":"10.1371\/journal.pone.0297508","article-title":"Student psychological well-being in higher education: the role of internal team environment, institutional, friends and family support and academic engagement","volume":"19","author":"Chaudhry","year":"2024","journal-title":"PLoS One"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/j.sleep.2021.10.032","article-title":"Validity and reliability of the Turkish version of single-item sleep quality scale in healthy adults","volume":"88","author":"Dereli","year":"2021","journal-title":"Sleep Med."},{"key":"ref17","doi-asserted-by":"publisher","first-page":"3874","DOI":"10.3390\/ijerph17113874","article-title":"Analysis of well-being and anxiety among university students","volume":"17","author":"Dias Lopes","year":"2020","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1525\/collabra.115","article-title":"Advances and open questions in the science of subjective well-being","volume":"4","author":"Diener","year":"2018","journal-title":"Collabra Psychol"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"2190697","DOI":"10.1080\/2331186X.2023.2190697","article-title":"Well-being of students in higher education: the importance of a student perspective","volume":"10","author":"Douwes","year":"2023","journal-title":"Cogent Educ."},{"key":"ref20","doi-asserted-by":"publisher","first-page":"163","DOI":"10.5502\/ijw.v12i2.1897","article-title":"A systematic review and meta-analysis of longitudinal studies of the antecedents and consequences of wellbeing among university students","volume":"12","author":"du Toit","year":"2022","journal-title":"Int. J. 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Modeling"},{"key":"ref23","author":"Jorgensen","year":"2022"},{"key":"ref24","doi-asserted-by":"crossref","DOI":"10.1007\/978-94-007-5640-3_11","article-title":"Mental health as a complete state: how the salutogenic perspective completes the picture","volume-title":"Bridging Occupational, Organizational and Public Health","author":"Keyes","year":"2014"},{"key":"ref25","volume-title":"Principles and Practice of Structural Equation Modeling","author":"Kline","year":"2023"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"509","DOI":"10.3928\/0048-5713-20020901-06","article-title":"The PHQ-9: a new depression diagnostic and severity measure","volume":"32","author":"Kroenke","year":"2002","journal-title":"Psychiatr. Ann."},{"key":"ref27","doi-asserted-by":"publisher","first-page":"1546","DOI":"10.3390\/bs15111546","article-title":"Psychometric assessment of screening measures for depression, anxiety, somatization, and life satisfaction in Honduran university students","volume":"15","author":"Landa-Blanco","year":"2025","journal-title":"Behav. Sci."},{"key":"ref28","doi-asserted-by":"publisher","first-page":"1352889","DOI":"10.3389\/fpsyt.2024.1352889","article-title":"Exploring suicide ideation in university students: sleep quality, social media, self-esteem, and barriers to seeking psychological help","volume":"15","author":"Landa-Blanco","year":"2024","journal-title":"Front. Psych."},{"key":"ref29","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1111\/j.0737-1209.2005.220304.x","article-title":"Health-promoting behaviors and psychosocial well-being of university students in Hong Kong","volume":"22","author":"Lee","year":"2005","journal-title":"Public Health Nurs."},{"key":"ref30","doi-asserted-by":"publisher","first-page":"2864","DOI":"10.3390\/ijerph16162864","article-title":"Changes in undergraduate students\u2019 psychological well-being as they experience university life","volume":"16","author":"Liu","year":"2019","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"E99","DOI":"10.1002\/da.20455","article-title":"Psychological well-being, depression, and anxiety in Japanese university students","volume":"26","author":"Liu","year":"2009","journal-title":"Depress. Anxiety"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1037\/1082-989X.9.3.275","article-title":"Structural equation models of latent interactions: evaluation of alternative estimation strategies and Indicator construction","volume":"9","author":"Marsh","year":"2004","journal-title":"Psychol. Methods"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/17439760.2025.2498130","article-title":"What is positive psychological functioning?","author":"Martela","year":"2025","journal-title":"J. Posit. Psychol."},{"key":"ref34","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1097\/PSY.0000000000001159","article-title":"Within-person temporal associations among self-reported physical activity, sleep, and well-being in college students","volume":"85","author":"McGowan","year":"2023","journal-title":"Psychosom. Med."},{"key":"ref35","doi-asserted-by":"publisher","first-page":"67","DOI":"10.4103\/aca.ACA_157_18","article-title":"Descriptive statistics and normality tests for statistical data","volume":"22","author":"Mishra","year":"2019","journal-title":"Ann. Card. Anaesth."},{"key":"ref36","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1016\/j.jad.2024.04.056","article-title":"Factors associated with high and low mental well-being in Spanish university students","volume":"356","author":"Navarra-Ventura","year":"2024","journal-title":"J. Affect. Disord."},{"key":"ref37","first-page":"41","article-title":"Development and testing of the health promotion model","volume":"24","author":"Pender","year":"1988","journal-title":"Cardiovasc. Nurs."},{"key":"ref38","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1037\/0021-9010.88.5.879","article-title":"Common method biases in behavioral research: a critical review of the literature and recommended remedies","volume":"88","author":"Podsakoff","year":"2003","journal-title":"J. Appl. Psychol."},{"key":"ref39","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1080\/07448481.2015.1085057","article-title":"Predictors of well-being among college students","volume":"64","author":"Ridner","year":"2016","journal-title":"J. Am. Coll. Heal."},{"key":"ref40","doi-asserted-by":"publisher","first-page":"1","DOI":"10.18637\/jss.v048.i02","article-title":"Lavaan: an R package for structural equation modeling","volume":"48","author":"Rosseel","year":"2012","journal-title":"J. Stat. Softw."},{"key":"ref41","doi-asserted-by":"publisher","first-page":"579","DOI":"10.4067\/S0034-98872019000500579","article-title":"Sintomatologia depresiva y bienestar psicol\u00f3gico en estudiantes universitarios chilenos","volume":"147","author":"Rossi","year":"2019","journal-title":"Rev. Med. Chile"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"1948","DOI":"10.3390\/healthcare13161948","article-title":"Stress, anxiety, and depression as psychological distress among college and undergraduate students: a scoping review of reviews guided by the socio-ecological model","volume":"13","author":"Roy","year":"2025","journal-title":"Healthcare"},{"key":"ref43","doi-asserted-by":"crossref","DOI":"10.4324\/9781315749105","volume-title":"A Beginner\u2019s Guide to Structural Equation Modeling","author":"Schumacker","year":"2015"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1177\/00131644211003261","article-title":"Sample size requirements for simple and complex mediation models","volume":"82","author":"Sim","year":"2022","journal-title":"Educ. Psychol. Meas."},{"key":"ref45","doi-asserted-by":"publisher","first-page":"1849","DOI":"10.5664\/jcsm.7478","article-title":"A new single-item sleep quality scale: results of psychometric evaluation in patients with chronic primary insomnia and depression","volume":"14","author":"Snyder","year":"2018","journal-title":"J. Clin. Sleep Med."},{"key":"ref46","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1007\/s11205-024-03382-z","article-title":"Measuring wellbeing across culture and context \u2013 are we getting it right? Evaluating the variation in wellbeing conceptualisations throughout the world","volume":"174","author":"Sollis","year":"2024","journal-title":"Soc. Indic. Res."},{"key":"ref47","doi-asserted-by":"publisher","first-page":"1092","DOI":"10.1001\/archinte.166.10.1092","article-title":"A brief measure for assessing generalized anxiety disorder","volume":"166","author":"Spitzer","year":"2006","journal-title":"Arch. Intern. Med."},{"key":"ref48","doi-asserted-by":"publisher","first-page":"1297256","DOI":"10.3389\/fpsyt.2023.1297256","article-title":"Relationship between sleep quality and subjective well-being: resilience as a mediator and belief in a just world as a moderator","volume":"14","author":"Su","year":"2023","journal-title":"Front. Psych."},{"key":"ref49","doi-asserted-by":"publisher","first-page":"1402680","DOI":"10.3389\/fpsyt.2024.1402680","article-title":"Exploring the interconnections of anxiety, depression, sleep problems and health-promoting lifestyles among Chinese university students: a comprehensive network approach","volume":"15","author":"Sun","year":"2024","journal-title":"Front. Psych."},{"key":"ref50","doi-asserted-by":"publisher","first-page":"e044236","DOI":"10.1136\/bmjopen-2020-044236","article-title":"Depression and its correlation with social support and health-promoting lifestyles among Chinese university students: a cross-sectional study","volume":"11","author":"Tang","year":"2021","journal-title":"BMJ Open"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"1864","DOI":"10.1111\/j.1365-2648.2010.05353.x","article-title":"Health promotion lifestyle profile-II: Chinese version short form","volume":"66","author":"Teng","year":"2010","journal-title":"J. Adv. Nurs."},{"key":"ref52","doi-asserted-by":"publisher","first-page":"101994","DOI":"10.1016\/j.evalprogplan.2021.101994","article-title":"Advances in monitoring and evaluation in low- and middle-income countries","volume":"89","author":"Thomas","year":"2021","journal-title":"Eval. Program Plann."},{"key":"ref53","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1159\/000376585","article-title":"The WHO-5 well-being index: a systematic review of the literature","volume":"84","author":"Topp","year":"2015","journal-title":"Psychother. Psychosom."},{"key":"ref54","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1080\/02643944.2022.2093963","article-title":"Wellbeing in higher education: a student perspective","volume":"40","author":"Walker","year":"2022","journal-title":"Pastoral Care in Educ."},{"key":"ref55","volume-title":"Psychometric Evaluation of the Health-promoting Lifestyle Profile II","author":"Walker","year":"1996"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1097\/00006199-198703000-00002","article-title":"The health-promoting lifestyle profile: development and psychometric characteristics","volume":"36","author":"Walker","year":"1987","journal-title":"Nurs. Res."},{"key":"ref57","author":"Waring","year":"2022"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1007\/s10804-009-9082-y","article-title":"Mental illness and mental health: the two continua model across the lifespan","volume":"17","author":"Westerhof","year":"2010","journal-title":"J. Adult Dev."},{"key":"ref59","volume-title":"Well-being measures in primary health care: The DepCare project","year":"1998"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"634285","DOI":"10.3389\/fpubh.2021.634285","article-title":"Bridging the gap: exploring the unique transition from home, school or college into university","volume":"9","author":"Worsley","year":"2021","journal-title":"Front. Public Health"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1016\/j.jad.2023.04.077","article-title":"Circadian rhythms and sleep quality among undergraduate students in China: the mediating role of health-promoting lifestyle behaviours","volume":"333","author":"Zhang","year":"2023","journal-title":"J. Affect. Disord."},{"key":"ref62","doi-asserted-by":"publisher","first-page":"1281571","DOI":"10.3389\/fpubh.2023.1281571","article-title":"Sleep quality and subjective well-being in healthcare students: examining the role of anxiety and depression","volume":"11","author":"Zhu","year":"2023","journal-title":"Front. 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