{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T13:23:51Z","timestamp":1771593831071,"version":"3.50.1"},"reference-count":82,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T00:00:00Z","timestamp":1770163200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychol."],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Academic stress represents a multifactorial psychophysiological phenomenon that can disrupt emotional well-being and autonomic balance in university students. Mindfulness-based interventions (MBIs) have shown promise in enhancing emotional regulation and physiological balance. This study aimed to evaluate the autonomic and psychophysiological effects of a 13-week mindfulness-based intervention (MBI) in university students.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A quasi-experimental longitudinal study was conducted with 93 Colombian university students (86% female; mean age\u202f=\u202f18.8\u202f\u00b1\u202f2.35\u202fyears). Participants were assigned to an intervention group (\n                      <jats:italic>n<\/jats:italic>\n                      \u202f=\u202f31) or a control group (\n                      <jats:italic>n<\/jats:italic>\n                      \u202f=\u202f62). The intervention consisted of weekly 60-min mindfulness sessions over 13\u202fweeks. Psychological (stress, anxiety, depression, loneliness, personality traits, psychological flexibility), behavioral (sleep, physical activity), and autonomic (heart rate and heart rate variability) measures were assessed pre- and post-intervention. Data were analyzed using ANCOVA adjusted for baseline values and relevant covariates (sex, age, sleep), Wilcoxon tests for within-group changes, and effect sizes estimated with Cliff\u2019s delta (\n                      <jats:italic>\u03b4<\/jats:italic>\n                      ) and rank-biserial correlations (rb). False discovery rate (FDR) correction was applied to control for multiple testing.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      After adjusting for covariates, no between-group effects remained significant after FDR correction, although small beneficial trends were observed in conscientiousness and HRV indices. Within-group analyses showed that participants in the intervention group exhibited significant increases in conscientiousness (\n                      <jats:italic>p<\/jats:italic>\n                      \u202f=\u202f0.039, rb\u202f=\u202f0.46), psychological flexibility (\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.01, rb\u202f=\u202f\u22120.51), and reduced loneliness (\n                      <jats:italic>p<\/jats:italic>\n                      \u202f=\u202f0.006, rb\u202f=\u202f\u22120.53). Anxiety and depressive symptoms remained stable in this group but increased in controls, indicating a potential protective effect. No significant changes were observed in perceived stress, sleep, physical activity, or academic performance.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The 13-week mindfulness intervention yielded selective improvements in emotional and autonomic regulation but limited effects on broader psychological and academic outcomes. These findings support a psychobiological model linking mindfulness to enhanced self-regulation and adaptive autonomic modulation. Mindfulness programs may benefit emotional resilience in university settings, though complementary strategies are recommended to enhance broader effects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical trial registration<\/jats:title>\n                    <jats:p>\n                      <jats:uri>https:\/\/anzctr.org.au\/Trial\/Registration\/TrialReview.aspx?id=389898<\/jats:uri>\n                      , ACTRN12625000984493.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpsyg.2026.1704398","type":"journal-article","created":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T05:34:35Z","timestamp":1770183275000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Autonomic and psychophysiological effects of a 13-week mindfulness-based intervention in university students"],"prefix":"10.3389","volume":"17","author":[{"given":"Juan Camilo","family":"Ben\u00edtez-Agudelo","sequence":"first","affiliation":[{"name":"Departamento de Ciencias Sociales, Corporacion Universitaria de la Costa","place":["Barranquilla, Colombia"]},{"name":"Universidad Sim\u00f3n Bol\u00edvar, Facultad de Ciencias de la Salud, Centro de Investigaciones en Ciencias de la Vida","place":["Barranquilla, Colombia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo","family":"Navarro-Jim\u00e9nez","sequence":"additional","affiliation":[{"name":"Universidad Sim\u00f3n Bol\u00edvar, Facultad de Ciencias de la Salud, Centro de Investigaciones en Ciencias de la Vida","place":["Barranquilla, Colombia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vicente Javier","family":"Clemente-Su\u00e1rez","sequence":"additional","affiliation":[{"name":"Departamento de Ciencias Sociales, Corporacion Universitaria de la Costa","place":["Barranquilla, Colombia"]},{"name":"Faculty of Medicine, Health and Sports, Universidad Europea de Madrid, Villaviciosa de Od\u00f3n","place":["Madrid, Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,2,4]]},"reference":[{"key":"ref1","first-page":"594","article-title":"The impact of a stress management intervention including cultural components on stress biomarker levels and mental health indicators among indigenous women","volume-title":"Journal of Behavioral Medicine","author":"Aker","year":"2023"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"2","DOI":"10.3390\/ijerph192416822","article-title":"Assessing physiological and psychological factors contributing to stress among medical students: implications for health","volume":"19","author":"Al-Rouq","year":"2022","journal-title":"Int. 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