{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T20:08:24Z","timestamp":1788898104975,"version":"build-2803163510"},"reference-count":69,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T00:00:00Z","timestamp":1773187200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychol."],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This systematic review and meta-analysis aimed to determine the pooled prevalence of anxiety among women with polycystic ovary syndrome (PCOS) in mainland China and explore the potential contributors related to anxiety prevalence among PCOS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We searched PubMed, EMBASE, Web of Science, CNKI, WanFang, and VIP databases from inception to January 2025. Pooled prevalence estimates were calculated using random-effects models, with subgroup analyses stratified by region, age, BMI, assessment tools, and diagnostic criteria. Heterogeneity was assessed by\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      statistics and meta-regression.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Thirty-five studies (8,655 participants) met inclusion criteria. The pooled anxiety prevalence was 32% (95% CI: 26\u201338%), with substantial heterogeneity (\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u202f=\u202f97.8%,\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.001). Subgroup analyses revealed higher prevalence in younger women (&amp;lt;26\u202fyears: 39% vs. \u226526\u202fyears: 25%), West China (36% vs. East\/Central China: 28%), and studies using GAD-7 (41% vs. SAS: 31%). Diagnostic criteria influenced estimates (Rotterdam: 31% vs. PRCHIS: 27%). Meta-regression identified no significant moderators. Sensitivity analyses confirmed robustness, and publication bias was nonsignificant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Anxiety affects nearly one-third of Chinese women with PCOS, with prevalence shaped by age, region, and assessment methodologies. Despite alignment with global trends, regional disparities underscore the need for culturally adapted mental health interventions. Clinicians should prioritize anxiety screening in PCOS management, particularly for younger women and underserved populations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpsyg.2026.1767567","type":"journal-article","created":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T06:52:13Z","timestamp":1773211933000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Anxiety prevalence among women with polycystic ovary syndrome in mainland China: a systematic review and meta-analysis"],"prefix":"10.3389","volume":"17","author":[{"given":"Shanshan","family":"Hong","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Quan Zhou Women\u2019s and Children\u2019s Hospital","place":["Quanzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenzhen","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Quanzhou First Hospital Affiliated to Fujian Medical University","place":["Quanzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liying","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Quan Zhou Women\u2019s and Children\u2019s Hospital","place":["Quanzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meiling","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Quan Zhou Women\u2019s and Children\u2019s Hospital","place":["Quanzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Li","sequence":"additional","affiliation":[{"name":"School of Basic Medical Sciences, Hunan University of Medicine","place":["Huaihua, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiawei","family":"Qin","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Quanzhou First Hospital Affiliated to Fujian Medical University","place":["Quanzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,3,11]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"e38647","DOI":"10.1097\/MD.0000000000038647","article-title":"Polycystic ovary syndrome and its multidimensional impacts on women's mental health: a narrative review","volume":"103","author":"Almhmoud","year":"2024","journal-title":"Medicine (Baltimore)"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"253","DOI":"10.3109\/09513590.2011.613966","article-title":"Polycystic ovary syndrome: infertility, cardiovascular, metabolic and obstetrical risks, laboratory and clinical outcomes -- the PICOLO study","volume":"28","author":"Aziz","year":"2012","journal-title":"Gynecol. 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