{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T09:26:25Z","timestamp":1784366785313,"version":"3.55.0"},"reference-count":71,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T00:00:00Z","timestamp":1772496000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychol."],"abstract":"\n Background<\/jats:title>\n Paediatric palliative care (PPC) is an early, holistic model addressing the physical, psychological, social, and spiritual needs of children with life-limiting or life-threatening conditions and their families. Parents frequently experience high psychological distress, and although psychological support is a core PPC component, empirical evidence on the effectiveness of interventions within this context remains limited, particularly across non-oncological conditions. This systematic review and meta-analysis aimed to evaluate the effectiveness of psychological interventions for parents of children eligible for PPC.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A systematic search of MEDLINE, Embase, CINAHL, APA PsycINFO, and CENTRAL was conducted in July 2024 and updated in Embase in November 2025. Randomized controlled trials evaluating psychological interventions for parents of children under 18\u202fyears eligible for PPC were included. Methodological quality was assessed using the Cochrane Risk of Bias tool for randomized trials (RoB 2). The review was conducted in accordance with PRISMA guidelines, and random-effects meta-analyses were performed where appropriate.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Thirty-six studies were included. Although the review aimed to capture studies involving parents of children with various life-limiting conditions eligible for PPC, the evidence base was almost exclusively oncology-focused: only one study was conducted within a PPC context, and all studies involved parents of children with cancer. The psychological interventions were heterogeneous and frequently multimodal, with cognitive-behavioural therapy being the most common approach. Meta-analyses showed primarily short-term significant moderate-to-large effect sizes, indicating improvements in anxiety (\n g<\/jats:italic>\n = \u22121.00; 95% CI: \u22121.49, \u22120.52; I\n 2<\/jats:sup>\n \u202f=\u202f94%), depression (g\u202f=\u202f\u22120.77; 95% CI: \u22121.15, \u22120.39; I\n 2<\/jats:sup>\n \u202f=\u202f85%), psychological distress (g\u202f=\u202f\u22120.39; 95% CI: \u22120.75, \u22120.04; I\n 2<\/jats:sup>\n \u202f=\u202f0%) and hope (\n g<\/jats:italic>\n \u202f=\u202f0.73; 95% CI: 0.20, 1.26; I\n 2<\/jats:sup>\n \u202f=\u202f0%). Evidence of long-term effects was limited, with improvements observed only for post-traumatic stress symptoms (\n g<\/jats:italic>\n \u202f=\u202f\u22120.29; 95% CI: \u22120.55, \u22120.03; I\n 2<\/jats:sup>\n \u202f=\u202f0%).\n <\/jats:p>\n <\/jats:sec>\n \n Discussion<\/jats:title>\n The findings suggest that psychological interventions, particularly those based on cognitive behavioural approaches, are effective in reducing psychological distress and enhancing positive psychological outcomes in the short term among parents of children with cancer who are eligible for PPC. However, the scarcity of studies explicitly conducted within PPC settings highlights the need for further high-quality trials across a wider range of life-limiting and life-threatening conditions.<\/jats:p>\n <\/jats:sec>\n \n Systematic review registration<\/jats:title>\n \n https:\/\/www.crd.york.ac.uk\/PROSPERO\/view\/CRD42024594171<\/jats:uri>\n , CRD42024594171\n <\/jats:p>\n <\/jats:sec>","DOI":"10.3389\/fpsyg.2026.1775937","type":"journal-article","created":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T06:48:03Z","timestamp":1772520483000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Effectiveness of psychological interventions for parents of children eligible for paediatric palliative care: a systematic review and meta-analysis"],"prefix":"10.3389","volume":"17","author":[{"given":"Yolanda","family":"\u00c1lvarez-P\u00e9rez","sequence":"first","affiliation":[{"name":"Canary Islands Health Research Institute Foundation (FIISC)","place":["Tenerife, Spain"]},{"name":"Evaluation Unit (SESCS), Canary Islands Health Service (SCS)","place":["Tenerife, Spain"]},{"name":"Network for Research on Chronicity, Primary Care, and Health Promotion (RICAPPS)","place":["Tenerife, Spain"]},{"name":"The Spanish Network of Agencies for Health Technology Assessment and Services of the National Health System (RedETS)","place":["Tenerife, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Duarte-D\u00edaz","sequence":"additional","affiliation":[{"name":"Canary Islands Health Research Institute Foundation (FIISC)","place":["Tenerife, Spain"]},{"name":"Evaluation Unit (SESCS), Canary Islands Health Service (SCS)","place":["Tenerife, Spain"]},{"name":"Network for Research on Chronicity, Primary Care, and Health Promotion (RICAPPS)","place":["Tenerife, Spain"]},{"name":"The Spanish Network of Agencies for Health Technology Assessment and Services of the National Health System (RedETS)","place":["Tenerife, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amado","family":"Rivero-Santana","sequence":"additional","affiliation":[{"name":"Canary Islands Health Research Institute Foundation (FIISC)","place":["Tenerife, Spain"]},{"name":"Evaluation Unit (SESCS), Canary Islands Health Service (SCS)","place":["Tenerife, Spain"]},{"name":"Network for Research on Chronicity, Primary Care, and Health Promotion (RICAPPS)","place":["Tenerife, Spain"]},{"name":"The Spanish Network of Agencies for Health Technology Assessment and Services of the National Health System (RedETS)","place":["Tenerife, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandra","family":"Abrante-Luis","sequence":"additional","affiliation":[{"name":"Canary Islands Health Research Institute Foundation (FIISC)","place":["Tenerife, Spain"]},{"name":"Evaluation Unit (SESCS), Canary Islands Health Service (SCS)","place":["Tenerife, Spain"]},{"name":"Network for Research on Chronicity, Primary Care, and Health Promotion (RICAPPS)","place":["Tenerife, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernat","family":"Carreras","sequence":"additional","affiliation":[{"name":"Department of Adult Psychiatry and Psychology, Institute of Neurosciences (ICN), Hospital Clinic","place":["Barcelona, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego","family":"Infante-Ventura","sequence":"additional","affiliation":[{"name":"Canary Islands Health Research Institute Foundation (FIISC)","place":["Tenerife, Spain"]},{"name":"Evaluation Unit (SESCS), Canary Islands Health Service (SCS)","place":["Tenerife, Spain"]},{"name":"Network for Research on Chronicity, Primary Care, and Health Promotion (RICAPPS)","place":["Tenerife, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanesa","family":"Ramos-Garc\u00eda","sequence":"additional","affiliation":[{"name":"Canary Islands Health Research Institute Foundation (FIISC)","place":["Tenerife, Spain"]},{"name":"Evaluation Unit (SESCS), Canary Islands Health Service (SCS)","place":["Tenerife, Spain"]},{"name":"Network for Research on Chronicity, Primary Care, and Health Promotion (RICAPPS)","place":["Tenerife, Spain"]},{"name":"The Spanish Network of Agencies for Health Technology Assessment and Services of the National Health System (RedETS)","place":["Tenerife, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alezandra","family":"Torres-Casta\u00f1o","sequence":"additional","affiliation":[{"name":"Canary Islands Health Research Institute Foundation (FIISC)","place":["Tenerife, Spain"]},{"name":"Evaluation Unit (SESCS), Canary Islands Health Service (SCS)","place":["Tenerife, Spain"]},{"name":"Network for Research on Chronicity, Primary Care, and Health Promotion (RICAPPS)","place":["Tenerife, Spain"]},{"name":"The Spanish Network of Agencies for Health Technology Assessment and Services of the National Health System (RedETS)","place":["Tenerife, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Estefan\u00eda","family":"Herrera-Ramos","sequence":"additional","affiliation":[{"name":"Canary Islands Health Research Institute Foundation (FIISC)","place":["Tenerife, Spain"]},{"name":"Evaluation Unit (SESCS), Canary Islands Health Service (SCS)","place":["Tenerife, Spain"]},{"name":"Network for Research on Chronicity, Primary Care, and Health Promotion (RICAPPS)","place":["Tenerife, Spain"]},{"name":"The Spanish Network of Agencies for Health Technology Assessment and Services of the National Health System (RedETS)","place":["Tenerife, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Luis","family":"Marrero G\u00f3mez","sequence":"additional","affiliation":[{"name":"Paediatric Palliative Care Unit, Hospital Universitario Virgen del Roc\u00edo","place":["Seville, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lilisbeth","family":"Perestelo-P\u00e9rez","sequence":"additional","affiliation":[{"name":"Evaluation Unit (SESCS), Canary Islands Health Service (SCS)","place":["Tenerife, Spain"]},{"name":"Network for Research on Chronicity, Primary Care, and Health Promotion (RICAPPS)","place":["Tenerife, Spain"]},{"name":"The Spanish Network of Agencies for Health Technology Assessment and Services of the National Health System (RedETS)","place":["Tenerife, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,3,3]]},"reference":[{"key":"ref1","article-title":"The role of psychology in palliative care","volume-title":"Monit. 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