{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T22:11:54Z","timestamp":1781561514578,"version":"3.54.5"},"reference-count":43,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychol."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Patients with lymphoma frequently experience significant psychosocial burden, including anxiety, depression, and impaired quality of life, which may persist throughout the disease trajectory. Coping strategies and nurse-led care are recognized as important psychosocial determinants; however, their interrelationships remain insufficiently explored in lymphoma populations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study sought to assess psychosocial distress, coping strategies, and quality of life in patients with lymphoma, while also investigating the influence of nurse-led care and the possible mediating effect of adaptive coping.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross-sectional observational study was conducted among 200 patients with Hodgkin and non-Hodgkin lymphoma at a tertiary hospital in China. Psychological distress was assessed using the Hospital Anxiety and Depression Scale (HADS), quality of life using the EORTC QLQ-C30, and coping strategies using the Brief COPE Inventory. Nurse-led care was quantified using a composite nursing support score. Multivariable regression, mediation analysis, and receiver operating characteristic (ROC) analysis were performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Patients exhibited moderate levels of anxiety (9.6\u202f\u00b1\u202f4.2) and depression (8.8\u202f\u00b1\u202f3.9), with 45 and 37% of participants, respectively, scoring above the clinical cut-off (HADS \u2265 11). Global quality of life was moderately impaired (58.3\u202f\u00b1\u202f16.5). Adaptive coping partially mediated the relationship between nursing support and quality of life. Higher nursing support scores were moderately and negatively correlated with both anxiety (\n                      <jats:italic>r<\/jats:italic>\n                      \u202f=\u202f\u22120.32,\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.001) and depression (\n                      <jats:italic>r<\/jats:italic>\n                      \u202f=\u202f\u22120.28, p\u202f&amp;lt;\u202f0.001), and positively correlated with global quality of life (\n                      <jats:italic>r<\/jats:italic>\n                      \u202f=\u202f0.27,\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.001). Nursing support demonstrated strong discriminative ability for clinically significant anxiety (AUC\u202f=\u202f0.89).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Lymphoma patients experience substantial psychosocial burden. Higher nursing support was associated with lower distress and better quality of life, partly through its correlation with adaptive coping strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpsyg.2026.1783426","type":"journal-article","created":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T04:24:52Z","timestamp":1777868692000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Psychosocial burden and coping strategies among lymphoma patients: a nurse-led hematology care approach"],"prefix":"10.3389","volume":"17","author":[{"given":"Yan","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Hematology, The First Affiliated Hospital of Soochow University","place":["Suzhou, Jiangsu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Hematology, The First Affiliated Hospital of Soochow University","place":["Suzhou, Jiangsu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haolei","family":"Niu","sequence":"additional","affiliation":[{"name":"Department of Hematology, The First Affiliated Hospital of Soochow University","place":["Suzhou, Jiangsu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,5,4]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1093\/jnci\/85.5.365","article-title":"The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology","volume":"85","author":"Aaronson","year":"1993","journal-title":"J. Natl. Cancer Inst."},{"key":"ref2","doi-asserted-by":"publisher","first-page":"790","DOI":"10.1016\/S1470-2045(12)70211-5","article-title":"Global cancer transitions according to the human development index (2008-2030): a population-based study","volume":"13","author":"Bray","year":"2012","journal-title":"Lancet Oncol."},{"key":"ref3","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1207\/s15327558ijbm0401_6","article-title":"You want to measure coping but your protocol\u2019s too long: consider the brief COPE","volume":"4","author":"Carver","year":"1997","journal-title":"Int. J. Behav. Med."},{"key":"ref4","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1037\/0022-3514.56.2.267","article-title":"Assessing coping strategies: a theoretically based approach","volume":"56","author":"Carver","year":"1989","journal-title":"J. Pers. Soc. Psychol."},{"key":"ref5","doi-asserted-by":"crossref","DOI":"10.5353\/th_b4171268","volume-title":"Coping Flexibility and Quality of life of cancer Patients","author":"Chan","year":""},{"key":"ref6","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1111\/ajr.12587","article-title":"Nurse-led psychological intervention reduces anxiety symptoms and improves quality of life following percutaneous coronary intervention for stable coronary artery disease","volume":"28","author":"Chang","year":"2020","journal-title":"Aust. J. Rural Health"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"105102","DOI":"10.1016\/j.ijnurstu.2025.105102","article-title":"The effect of nurse-led enhanced supportive care as an early primary palliative care approach for patients with advanced cancer: a randomized controlled trial","volume":"168","author":"Choi","year":"2025","journal-title":"Int. J. Nurs. Stud."},{"key":"ref8","doi-asserted-by":"publisher","first-page":"114","DOI":"10.7861\/futurehosp.3-2-114","article-title":"Person-centred care: what is it and how do we get there?","volume":"3","author":"Coulter","year":"2016","journal-title":"Future Hosp J."},{"key":"ref9","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1177\/1359105310383605","article-title":"Breast cancer patients' topic avoidance and psychological distress: the mediating role of coping","volume":"16","author":"Donovan-Kicken","year":"2011","journal-title":"J. Health Psychol."},{"key":"ref10","volume-title":"Review for \"Long-term Outcomes in Hodgkin Lymphoma Survivors. Temporary Trends and Comparison with general Population\"","author":"Emmanuel","year":"2023"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1037\/0003-066X.55.6.647","article-title":"Positive affect and the other side of coping","volume":"55","author":"Folkman","year":"2000","journal-title":"Am. Psychol."},{"key":"ref12","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1186\/s12913-024-12058-w","article-title":"Person-centred care in oncological home services: a scoping review of patients' and caregivers' experience and needs","volume":"25","author":"Furmenti","year":"2025","journal-title":"BMC Health Serv. Res."},{"key":"ref13","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1207\/s15327906mbr2603_7","article-title":"How many subjects does it take to do a regression analysis","volume":"26","author":"Green","year":"1991","journal-title":"Multivariate Behav Res."},{"key":"ref14","doi-asserted-by":"publisher","first-page":"3417","DOI":"10.1002\/cncr.25053","article-title":"A population-based study of follow-up care for Hodgkin lymphoma survivors: opportunities to improve surveillance for relapse and late effects","volume":"116","author":"Hodgson","year":"2010","journal-title":"Cancer"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"e0229345","DOI":"10.1371\/journal.pone.0229345","article-title":"A solution to minimum sample size for regressions","volume":"15","author":"Jenkins","year":"2020","journal-title":"PLoS One"},{"key":"ref16","volume-title":"Stress, Appraisal and Coping","author":"Kavanagh","year":"2009"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1111\/j.1751-9004.2007.00016.x","article-title":"Cultural shaping of self, emotion, and well-being: how does it work?","volume":"1","author":"Kitayama","year":"2007","journal-title":"Soc. Personal. Psychol. Compass"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"546","DOI":"10.3390\/healthcare11040546","article-title":"The role of nurse on the treatment decision support for older people with Cancer: a systematic review","volume":"11","author":"Komatsu","year":"2023","journal-title":"Healthcare (Basel)"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"E186","DOI":"10.1097\/NCC.0000000000000672","article-title":"Factors affecting the levels of satisfaction with nurse-patient communication among oncology patients","volume":"43","author":"Lam","year":"2020","journal-title":"Cancer Nurs."},{"key":"ref20","doi-asserted-by":"publisher","first-page":"e405","DOI":"10.1016\/S1470-2045(23)00463-1","article-title":"Correction to lancet Oncol","volume":"24","year":"2023","journal-title":"Lancet Oncol."},{"key":"ref21","doi-asserted-by":"publisher","first-page":"842","DOI":"10.1007\/s11764-019-00802-9","article-title":"Prevalence and factors associated with fear of recurrence in a mixed sample of young adults with cancer","volume":"13","author":"Lane","year":"2019","journal-title":"J. Cancer Surviv."},{"key":"ref22","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1007\/s00520-025-09906-8","article-title":"Study on the effect of nursing intervention based on the broaden-and-build theory on the psychosocial adaptability of patients with minimally invasive ablation of liver cancer","volume":"33","author":"Li","year":"2025","journal-title":"Support Care Cancer"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"1449","DOI":"10.1007\/s00520-011-1228-3","article-title":"Mismatch of desired versus perceived social support and associated levels of anxiety and depression in newly diagnosed cancer patients","volume":"20","author":"Linden","year":"2012","journal-title":"Support Care Cancer"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"1442","DOI":"10.1080\/10410236.2021.1901422","article-title":"Cultural differences in Cancer information acquisition: Cancer risk perceptions, fatalistic beliefs, and worry as predictors of Cancer information seeking and avoidance in the U.S. and China","volume":"37","author":"Lu","year":"2022","journal-title":"Health Commun."},{"key":"ref25","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1186\/s12912-024-01718-1","article-title":"Oncology nurses\u2019 experiences of providing emotional support for cancer patients: a qualitative study","volume":"23","author":"Lyu","year":"2024","journal-title":"BMC Nurs."},{"key":"ref26","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1037\/0033-295X.98.2.224","article-title":"Culture and the self: implications for cognition, emotion, and motivation","volume":"98","author":"Markus","year":"1991","journal-title":"Psychol. Rev."},{"key":"ref27","doi-asserted-by":"publisher","first-page":"5023","DOI":"10.1007\/s00520-019-05292-0","article-title":"A nurse practitioner-led model of care improves access, early assessment and integration of oncology services: an evaluation study","volume":"28","author":"Oatley","year":"2020","journal-title":"Support Care Cancer"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"776","DOI":"10.3390\/jpm11080776","article-title":"Patient-centered Care for Patients with depression or anxiety disorder","volume":"11","author":"Pinho","year":"2021","journal-title":"An Integrative Review. J Pers Med."},{"key":"ref29","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1002\/nur.20147","article-title":"The content validity index: are you sure you know what's being reported? Critique and recommendations","volume":"29","author":"Polit","year":"2006","journal-title":"Res Nurs Health."},{"key":"ref30","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1002\/nur.20199","article-title":"Is the CVI an acceptable indicator of content validity? Appraisal and recommendations","volume":"30","author":"Polit","year":"2007","journal-title":"Res Nurs Health."},{"key":"ref31","doi-asserted-by":"publisher","first-page":"1276","DOI":"10.1002\/sim.7992","article-title":"Minimum sample size for developing a multivariable prediction model: PART II\u2014binary and time-to-event outcomes","volume":"38","author":"Riley","year":"2019","journal-title":"Stat. Med."},{"key":"ref32","doi-asserted-by":"publisher","first-page":"1150","DOI":"10.1037\/0022-3514.78.6.1150","article-title":"Coping through emotional approach: scale construction and validation","volume":"78","author":"Stanton","year":"2000","journal-title":"J. Pers. Soc. Psychol."},{"key":"ref33","doi-asserted-by":"publisher","first-page":"209","DOI":"10.3322\/caac.21660","article-title":"Global Cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J. Clin."},{"key":"ref34","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1177\/1043454220919713","article-title":"Psychosocial interventions for adolescents and Young adults with Cancer: an integrative review","volume":"37","author":"Thornton","year":"2020","journal-title":"J. Pediatr. Oncol. Nurs."},{"key":"ref35","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1016\/B978-0-323-69494-0.00023-3","article-title":"Cancer complications in patients with hematologic malignancies","author":"Valencia-Sanchez","year":"2021","journal-title":"Neuro-Oncol. Clin. Neurol."},{"key":"ref36","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1002\/pon.5322","article-title":"Integrating oncology, psychosocial, and medical care: the path forward","volume":"29","author":"Wender","year":"2020","journal-title":"Psychooncology"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1097\/00004650-199704000-00009","article-title":"Caring in patient-focused care: the relationship of patients' perceptions of holistic nurse caring to their levels of anxiety","volume":"11","author":"Williams","year":"1997","journal-title":"Holist. Nurs. Pract."},{"key":"ref38","doi-asserted-by":"publisher","first-page":"211","DOI":"10.15761\/HMO.1000211","article-title":"Pilot study assessing distressors affecting patients with Cancer using the distress thermometer screening tool","volume":"5","author":"Yamout","year":"2020","journal-title":"Hematol. Med. Oncol."},{"key":"ref39","doi-asserted-by":"publisher","first-page":"e555","DOI":"10.1016\/S1470-2045(20)30612-4","article-title":"Essential oncology nursing care along the cancer continuum","volume":"21","author":"Young","year":"2020","journal-title":"Lancet Oncol."},{"key":"ref40","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1002\/1099-1611(200101\/02)10:1<19::AID-PON501>3.0.CO;2-6","article-title":"The prevalence of psychological distress by cancer site","volume":"10","author":"Zabora","year":"2001","journal-title":"Psychooncology"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"1356","DOI":"10.1186\/s12912-025-03981-2","article-title":"Effectiveness of nurse-led mHealth interventions on symptom outcomes in adult patients with cancer: a systematic review and meta-analysis","volume":"24","author":"Zhang","year":"2025","journal-title":"BMC Nurs."},{"key":"ref42","doi-asserted-by":"publisher","first-page":"e29914","DOI":"10.1097\/MD.0000000000029914","article-title":"Effects of psychological nursing care on anxiety and depression in perioperative patients with lung cancer: a systematic review and meta-analysis","volume":"101","author":"Zhu","year":"2022","journal-title":"Medicine (Baltimore)"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1111\/j.1600-0447.1983.tb09716.x","article-title":"The hospital anxiety and depression scale","volume":"67","author":"Zigmond","year":"1983","journal-title":"Acta Psychiatr. Scand."}],"container-title":["Frontiers in Psychology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpsyg.2026.1783426\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T04:24:53Z","timestamp":1777868693000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpsyg.2026.1783426\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,4]]},"references-count":43,"alternative-id":["10.3389\/fpsyg.2026.1783426"],"URL":"https:\/\/doi.org\/10.3389\/fpsyg.2026.1783426","relation":{},"ISSN":["1664-1078"],"issn-type":[{"value":"1664-1078","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,4]]},"article-number":"1783426"}}