{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T17:11:24Z","timestamp":1776100284215,"version":"3.50.1"},"reference-count":45,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2019,7,9]],"date-time":"2019-07-09T00:00:00Z","timestamp":1562630400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100011912","name":"Taipei Veterans General Hospital","doi-asserted-by":"publisher","award":["V108C-038"],"award-info":[{"award-number":["V108C-038"]}],"id":[{"id":"10.13039\/501100011912","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychiatry"],"DOI":"10.3389\/fpsyt.2019.00481","type":"journal-article","created":{"date-parts":[[2019,7,9]],"date-time":"2019-07-09T05:24:27Z","timestamp":1562649867000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":24,"title":["Risk of Depressive Disorders Following Myasthenia Gravis: A Nationwide Population-Based Retrospective Cohort Study"],"prefix":"10.3389","volume":"10","author":[{"given":"Hsuan-Te","family":"Chu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chih-Chieh","family":"Tseng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chih-Sung","family":"Liang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ta-Chuan","family":"Yeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li-Yu","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Albert C.","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shih-Jen","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheng-Che","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2019,7,9]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199406233302507","article-title":"Myasthenia gravis","volume":"330","author":"Drachman","year":"1994","journal-title":"N Engl J Med"},{"key":"B2","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1055\/s-2004-829585","article-title":"Pathophysiology of myasthenia gravis","volume":"24","author":"Hughes","year":"2004","journal-title":"Semin Neurol"},{"key":"B3","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/S0022-510X(99)00205-1","article-title":"Does myasthenia gravis affect the brain","volume":"170","author":"Keesey","year":"1999","journal-title":"J Neurol Sci"},{"key":"B4","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1159\/000311012","article-title":"Nationwide population-based epidemiological study of myasthenia gravis in Taiwan","volume":"35","author":"Lai","year":"2010","journal-title":"Neuroepidemiology"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.38.8.1173","article-title":"Memory dysfunction in myasthenia gravis: evidence for central cholinergic effects","volume":"38","author":"Tucker","year":"1988","journal-title":"Neurology"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.26.4.311","article-title":"Rapid eye movement sleep alterations in myasthenia gravis","volume":"26","author":"Papazian","year":"1976","journal-title":"Neurology"},{"key":"B7","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1016\/S1474-4422(09)70063-8","article-title":"Autoimmune myasthenia gravis: emerging clinical and biological heterogeneity","volume":"8","author":"Meriggioli","year":"2009","journal-title":"Lancet Neurol"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1007\/s100720100066","article-title":"Health-related quality of life in patients with myasthenia gravis and the relationship between patient-oriented assessment and conventional measurements","volume":"22","author":"Padua","year":"2001","journal-title":"Neurol Sci"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21016","article-title":"Disease-specific measure of quality of life for myasthenia gravis","volume":"38","author":"Mullins","year":"2008","journal-title":"Muscle Nerve"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1002\/mus.1034","article-title":"Quality of life and well-being of patients with myasthenia gravis","volume":"24","author":"Paul","year":"2001","journal-title":"Muscle Nerve"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.151.7.979","article-title":"The prevalence and distribution of major depression in a national community sample: the National Comorbidity Survey","volume":"151","author":"Blazer","year":"1994","journal-title":"Am J Psychiatry"},{"key":"B12","doi-asserted-by":"publisher","first-page":"976","DOI":"10.1176\/ajp.145.8.976","article-title":"Psychiatric disorder in a sample of the general population with and without chronic medical conditions","volume":"145","author":"Wells","year":"1988","journal-title":"Am J Psychiatry"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2017.03.006","article-title":"Epidemiology of pharmaceutically treated depression and treatment resistant depression in Taiwan","volume":"252","author":"Fife","year":"2017","journal-title":"Psychiatry Res"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1016\/0163-8343(96)00065-5","article-title":"The impact of major depression on chronic medical illness","volume":"18","author":"Katon","year":"1996","journal-title":"Gen Hosp Psychiatry"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.145.11.1351","article-title":"The NIMH Depression Awareness, Recognition, and Treatment Program: structure, aims, and scientific basis","volume":"145","author":"Regier","year":"1988","journal-title":"Am J Psychiatry"},{"key":"B16","first-page":"65","article-title":"Somatic symptoms and depression","volume":"29","author":"Katon","year":"1989","journal-title":"J Family Pract"},{"key":"B17","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1037\/0278-6133.14.1.88","article-title":"Major depression and medication adherence in elderly patients with coronary artery disease","volume":"14","author":"Carney","year":"1995","journal-title":"Health Psychol"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.145.3.269","article-title":"Psychiatric aspects of diabetes mellitus","volume":"145","author":"Surridge","year":"1984","journal-title":"Br J Psychiatry"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1016\/j.ncl.2006.03.003","article-title":"Cytokine, sickness behavior, and depression","volume":"24","author":"Dantzer","year":"2006","journal-title":"Neurol Clin"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1177\/0333102412469738","article-title":"Cluster headache is associated with an increased risk of depression: a nationwide population-based cohort study","volume":"33","author":"Liang","year":"2013","journal-title":"Cephalalgia"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jagp.2014.10.011","article-title":"Increased risk of depression in patients with Parkinson disease: a nationwide cohort study","volume":"23","author":"Hsu","year":"2015","journal-title":"Am J Geriatr Psychiatry"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1097\/DBP.0b013e3182829f2b","article-title":"Tourette syndrome and risk of depression: a population-based cohort study in Taiwan","volume":"34","author":"Chou","year":"2013","journal-title":"J Dev Behav Pediatr"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.2165\/00023210-200721060-00004","article-title":"Mood and anxiety disorders in patients with myasthenia gravis","volume":"21","author":"Kulaksizoglu","year":"2007","journal-title":"CNS Drugs"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-009-0194-8","article-title":"Social support and self-efficacy in patients with myasthenia gravis: a common pathway towards positive health outcomes","volume":"31","author":"Raggi","year":"2010","journal-title":"Neurol Sci"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.2006.00729.x","article-title":"Quality of life in patients with multiple sclerosis in Serbia","volume":"115","author":"Drulovic","year":"2007","journal-title":"Acta Neurol Scand"},{"key":"B26","first-page":"71","article-title":"Health-related quality of life in patients with myotonic dystrophy type 1 and amyotrophic lateral sclerosis","volume":"110","author":"Peric","year":"2010","journal-title":"Acta Neurol Belg"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2016.03.020","article-title":"Risk of depressive disorders following sudden sensorineural hearing loss: a nationwide population-based retrospective cohort study","volume":"197","author":"Tseng","year":"2016","journal-title":"J Affect Disord"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.150388","article-title":"Risk of psychiatric disorders following ankylosing spondylitis: a nationwide population-based retrospective cohort study","volume":"43","author":"Shen","year":"2016","journal-title":"J Rheumatol"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.141361","article-title":"Risk of psychiatric disorders following primary Sjogren syndrome: a nationwide population-based retrospective cohort study","volume":"42","author":"Shen","year":"2015","journal-title":"J Rheumatol"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1988.tb05148.x","article-title":"Psychiatric disturbances associated with myasthenia gravis","volume":"77","author":"Magni","year":"1988","journal-title":"Acta Psychiatr Scand"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1001\/2012.jama.11975","article-title":"Association between nucleoside analogues and risk of hepatitis B virus-related hepatocellular carcinoma recurrence following liver resection","volume":"308","author":"Wu","year":"2012","journal-title":"JAMA"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1011600","article-title":"Immediate versus delayed IUD insertion after uterine aspiration","volume":"364","author":"Bednarek","year":"2011","journal-title":"N Engl J Med"},{"key":"B33","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1111\/ene.12599","article-title":"Myasthenia gravis and risks for comorbidity","volume":"22","author":"Gilhus","year":"2015","journal-title":"Eur J Neurol"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(15)00145-3","article-title":"Myasthenia gravis: subgroup classification and therapeutic strategies","volume":"14","author":"Gilhus","year":"2015","journal-title":"Lancet Neurol"},{"key":"B35","doi-asserted-by":"publisher","first-page":"e000313","DOI":"10.1136\/bmjopen-2011-000313","article-title":"Factors associated with depressive state in patients with myasthenia gravis: a multicentre cross-sectional study","volume":"1","author":"Suzuki","year":"2011","journal-title":"BMJ open"},{"key":"B36","doi-asserted-by":"publisher","first-page":"295","DOI":"10.4274\/npa.y5611","article-title":"The relationship of symptoms of anxiety and depression with disease severity and treatment modality in myasthenia gravis: a cross-sectional study","volume":"50","author":"Aysal","year":"2013","journal-title":"N\u00f6ro Psikiyatri Ar\u015fivi"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2006.01476.x","article-title":"Guidelines for the treatment of autoimmune neuromuscular transmission disorders","volume":"13","author":"Skeie","year":"2006","journal-title":"Eur J Neurol"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.3109\/10673229809000307","article-title":"Mood symptoms during corticosteroid therapy: a review","volume":"5","author":"Brown","year":"1998","journal-title":"Harv Rev Psychiatry"},{"key":"B39","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1016\/S0306-4530(99)00007-4","article-title":"Effects of acute prednisone administration on memory, attention and emotion in healthy human adults","volume":"24","author":"Schmidt","year":"1999","journal-title":"Psychoneuroendocrinology"},{"key":"B40","first-page":"1361","volume-title":"Psychiatric adverse effects of corticosteroids, Mayo Clinic Proceedings","author":"Warrington","year":"2006"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(71)90043-9","article-title":"Psychopathology associated with myasthenia gravis and its treatment by psychotherapeutically oriented group counseling","volume":"24","author":"Schwartz","year":"1971","journal-title":"J Clin Epidemiol"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1159\/000287397","article-title":"Symptom changes during the psychotherapy of patients with myasthenia gravis","volume":"32","author":"K\u00fctemeyer","year":"1979","journal-title":"Psychother Psychosom"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1016\/S0924-977X(98)00012-1","article-title":"Fluoxetine treatment for weight reduction in steroid-induced obesity: a pilot study in myasthenia gravis patients","volume":"9","author":"Achiron","year":"1999","journal-title":"Eur Neuropsychopharmacol"},{"key":"B44","volume-title":"Citalopram treatment of depression in myasthenia gravis patients\u2014an open study, European Neuropsychopharmacology","author":"Kulaksizoglu","year":"2005"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1080\/10401230490522052","article-title":"Electroconvulsive therapy in myasthenia gravis","volume":"16","author":"Calarge","year":"2004","journal-title":"Ann Clin Psychiatry"}],"container-title":["Frontiers in Psychiatry"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fpsyt.2019.00481\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,19]],"date-time":"2019-09-19T18:43:16Z","timestamp":1568918596000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fpsyt.2019.00481\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,9]]},"references-count":45,"alternative-id":["10.3389\/fpsyt.2019.00481"],"URL":"https:\/\/doi.org\/10.3389\/fpsyt.2019.00481","relation":{},"ISSN":["1664-0640"],"issn-type":[{"value":"1664-0640","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7,9]]},"article-number":"481"}}