{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T14:09:07Z","timestamp":1765807747110,"version":"3.41.2"},"reference-count":54,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2019,11,11]],"date-time":"2019-11-11T00:00:00Z","timestamp":1573430400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychiatry"],"DOI":"10.3389\/fpsyt.2019.00814","type":"journal-article","created":{"date-parts":[[2019,11,11]],"date-time":"2019-11-11T14:07:06Z","timestamp":1573481226000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":22,"title":["A Method to Provoke Obsessive Compulsive Symptoms for Basic Research and Clinical Interventions"],"prefix":"10.3389","volume":"10","author":[{"given":"Aron","family":"Tendler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elyssa","family":"Sisko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noam","family":"Barnea-Ygael","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abraham","family":"Zangen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric A.","family":"Storch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2019,11,11]]},"reference":[{"key":"B1","unstructured":"Press Announcements 0000 > FDA permits marketing of transcranial magnetic stimulation for treatment of obsessive compulsive disorder"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2017.09.004","article-title":"Clinical and electrophysiological outcomes of deep TMS over the medial prefrontal and anterior cingulate cortices in OCD patients","volume":"11","author":"Carmi","year":"2018","journal-title":"Brain Stimul"},{"key":"B3","doi-asserted-by":"crossref","DOI":"10.1176\/appi.ajp.2019.18101180","article-title":"Efficacy and safety of deep transcranial magnetic stimulation for obsessive-compulsive disorder: a prospective multicenter randomized double-blind placebo-controlled trial","volume-title":"Am J Psychiatry","author":"Carmi","year":"2019"},{"key":"B4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.neuroimage.2016.12.083","article-title":"Using neuroimaging to individualize TMS treatment for depression: Toward a new paradigm for imaging-guided intervention","volume":"148","author":"Luber","year":"2017","journal-title":"Neuroimage"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2010.06.038","article-title":"Cognitive-emotional reactivation during deep transcranial magnetic stimulation over the prefrontal cortex of depressive patients affects antidepressant outcome","volume":"128","author":"Isserles","year":"2011","journal-title":"J Affect Disord"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2014.05.020","article-title":"Smoking cessation induced by deep repetitive transcranial magnetic stimulation of the prefrontal and insular cortices: a prospective, randomized controlled trial","volume":"76","author":"Dinur-Klein","year":"2014","journal-title":"Biol Psychiatry"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2012.07.008","article-title":"Effectiveness of deep transcranial magnetic stimulation combined with a brief exposure procedure in post-traumatic stress disorder\u2013a pilot study","volume":"6","author":"Isserles","year":"2013","journal-title":"Brain Stimul"},{"key":"B8","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1146\/annurev.psych.55.090902.142050","article-title":"The neurobiology of consolidations, or, how stable is the engram","volume":"55","author":"Dudai","year":"2004","journal-title":"Annu Rev Psychol"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2006.03.010","article-title":"Reconsolidation: the advantage of being refocused","volume":"16","author":"Dudai","year":"2006","journal-title":"Curr Opin Neurobiol"},{"key":"B10","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1016\/j.brs.2018.12.727","article-title":"How much can patients expect to improve with six weeks of deep TMS for OCD","volume":"12","author":"Gersner","year":"2019","journal-title":"Brain Stimul"},{"key":"B11","doi-asserted-by":"publisher","first-page":"e140","DOI":"10.1016\/j.brs.2019.03.058","article-title":"Deep TMS for OCD with the H7 Coil: Community Case Series","volume":"12","author":"Tendler","year":"2019","journal-title":"Brain Stimul"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1126\/science.1223006","article-title":"Disruption of reconsolidation erases a fear memory trace in the human amygdala","volume":"337","author":"Agren","year":"2012","journal-title":"Science"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1320322110","article-title":"Extinction during reconsolidation of threat memory diminishes prefrontal cortex involvement","volume":"110","author":"Schiller","year":"2013","journal-title":"Proc Natl Acad Sci USA"},{"key":"B14","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1038\/nature08637","article-title":"Preventing the return of fear in humans using reconsolidation update mechanisms","volume":"463","author":"Schiller","year":"2010","journal-title":"Nature"},{"key":"B15","first-page":"e3893","article-title":"Extinction training during the reconsolidation window prevents recovery of fear","volume-title":"J Vis Exp","author":"Schiller","year":"2012"},{"key":"B16","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1101\/lm.486107","article-title":"Reconsolidation of declarative memory in humans","volume":"14","author":"Forcato","year":"2007","journal-title":"Learn Mem"},{"key":"B17","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1101\/lm.365707","article-title":"Reconsolidation of episodic emories: a subtle reminder triggers integration of new information","volume":"14","author":"Hupbach","year":"2007","journal-title":"Learn Mem"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1101\/lm.338406","article-title":"In memory of consolidation","volume":"13","author":"Sara","year":"2006","journal-title":"Learn Mem"},{"key":"B19","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1101\/lm.7.2.73","article-title":"Retrieval and reconsolidation: toward a neurobiology of remembering","volume":"7","author":"Sara","year":"2000","journal-title":"Learn Mem"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2004.11.001","article-title":"Mechanisms of memory stabilization: are consolidation and reconsolidation similar or distinct processes","volume":"28","author":"Alberini","year":"2005","journal-title":"Trends Neurosci"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1038\/nature01930","article-title":"Dissociable stages of human memory consolidation and reconsolidation","volume":"425","author":"Walker","year":"2003","journal-title":"Nature"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.1997.0154","article-title":"Emotional memory and psychopathology","volume":"352","author":"Ledoux","year":"1997","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2009.06634.x","article-title":"Impairment of aversive memory reconsolidation by localized intracranial electrical stimulation","volume":"29","author":"Stehberg","year":"2009","journal-title":"Eur J Neurosci"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2010.07.047","article-title":"Modification of existing human motor memories is enabled by primary cortical processing during memory reactivation","volume":"20","author":"Censor","year":"2010","journal-title":"Curr Biol"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2971-04.2004","article-title":"Characterization of fear memory reconsolidation","volume":"24","author":"Duvarci","year":"2004","journal-title":"J Neurosci"},{"key":"B26","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1891\/0889-8391.30.3.190","article-title":"An initial test of reconsolidation in disgust-related learning and extinction","volume":"30","author":"Olatunji","year":"2016","journal-title":"J Cognit Psychother"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1016\/S0924-977X(14)71071-5","article-title":"6.b.004 Disgust counterconditioning during reconsolidation reduces liking of and abolishes attentional bias to alcohol cues","volume":"24","author":"Das","year":"2014","journal-title":"Eur Neuropsychopharmacol"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2466-06.2006","article-title":"Reconsolidation and extinction of conditioned fear: inhibition and potentiation","volume":"26","author":"Lee","year":"2006","journal-title":"J Neurosci"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1038\/35021052","article-title":"Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval","volume":"406","author":"Nader","year":"2000","journal-title":"Nature"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1038\/nn1871","article-title":"Synapse-specific reconsolidation of distinct fear memories in the lateral amygdala","volume":"10","author":"Doy\u00e8re","year":"2007","journal-title":"Nat Neurosci"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2004.08.018","article-title":"Disruption of reconsolidation but not consolidation of auditory fear conditioning by noradrenergic blockade in the amygdala","volume":"129","author":"Debiec","year":"2004","journal-title":"Neuroscience"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1038\/nn.2271","article-title":"Beyond extinction: erasing human fear responses and preventing the return of fear","volume":"12","author":"Kindt","year":"2009","journal-title":"Nat Neurosci"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2013.12050651","article-title":"Response to learned threat: an FMRI study in adolescent and adult anxiety","volume":"170","author":"Britton","year":"2013","journal-title":"Am J Psychiatry"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1002\/da.22389","article-title":"A meta-analysis of cognitive behavior therapy and medication for child obsessive-compulsive disorder: moderators of treatment efficacy, response, and remission","volume":"32","author":"McGuire","year":"2015","journal-title":"Depress Anxiety"},{"key":"B35","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.jpsychires.2012.08.020","article-title":"Cognitive-behavioral therapy for obsessive-compulsive disorder: a meta-analysis of treatment outcome and moderators","volume":"47","author":"Olatunji","year":"2013","journal-title":"J Psychiatr Res"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpra.2017.12.003","article-title":"An inhibitory learning approach to cognitive-behavioral therapy for children and adolescents","volume":"26","author":"McGuire","year":"2019","journal-title":"Cognit Behav Pract"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1989.01810060025005","article-title":"Anxiety and cerebral blood flow during behavioral challenge. dissociation of central from peripheral and subjective measures","volume":"46","author":"Zohar","year":"1989","journal-title":"Arch Gen Psychiatry"},{"key":"B38","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1001\/archpsyc.1994.03950010062008","article-title":"Regional cerebral blood flow measured during symptom provocation in obsessive-compulsive disorder using oxygen 15-labeled carbon dioxide and positron emission tomography","volume":"51","author":"Rauch","year":"1994","journal-title":"Arch Gen Psychiatry"},{"key":"B39","first-page":"26","article-title":"Functional neuroanatomy of obsessive-compulsive disorder","volume":"57","author":"Trivedi","year":"1996","journal-title":"J Clin Psychiatry"},{"key":"B40","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1192\/S0007125000297870","article-title":"Neuroimaging and frontal-subcortical circuitry in obsessive-compulsive disorder","volume":"173","author":"Saxena","year":"1998","journal-title":"Br J Psychiatry Suppl"},{"key":"B41","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1053\/scnp.2001.21833","article-title":"Brain-behavior relationships in obsessive-compulsive disorder","volume":"6","author":"Saxena","year":"2001","journal-title":"Semin Clin Neuropsychiatry"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2005.11.024","article-title":"The neurocircuitry of obsessive-compulsive disorder and disgust","volume":"30","author":"Husted","year":"2006","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"B43","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/j.biopsych.2016.10.006","article-title":"Comparative multimodal meta-analysis of structural and functional brain abnormalities in autism spectrum disorder and obsessive-compulsive disorder","volume":"82","author":"Carlisi","year":"2017","journal-title":"Biol Psychiatry"},{"volume-title":"The organization of behavior.","year":"1949","author":"Hebb","key":"B44"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2018.10.008","article-title":"Interhemispheric cortico-cortical paired associative stimulation of the prefrontal cortex jointly modulates frontal asymmetry and emotional reactivity","volume":"12","author":"Zibman","year":"2019","journal-title":"Brain Stimul"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2018.05.083","article-title":"Strengthening functionally specific neural pathways with transcranial brain stimulation","volume":"28","author":"Chiappini","year":"2018","journal-title":"Curr Biol"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1016\/0005-7967(66)90023-4","article-title":"Modification of expectations in cases with obsessional rituals","volume":"4","author":"Meyer","year":"1966","journal-title":"Behav Res Ther"},{"key":"B48","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1037\/0033-2909.99.1.20","article-title":"Emotional processing of fear: exposure to corrective information","volume":"99","author":"Foa","year":"1986","journal-title":"Psychol Bull"},{"key":"B49","first-page":"3","article-title":"Pathological anxiety: emotional processing in etiology and treatment","volume-title":"Emotional Processing Theory: An Update","author":"Foa","year":"2006"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1080\/14737175.2016.1199276","article-title":"Extinction learning in childhood anxiety disorders, obsessive compulsive disorder and post-traumatic stress disorder: implications for treatment","volume":"16","author":"McGuire","year":"2016","journal-title":"Expert Rev Neurother"},{"key":"B51","article-title":"Provocation of obsessive-compulsive symptoms: a quantitative voxel-based meta-analysis of functional neuroimaging studies","volume":"33","author":"Rotge","year":"2008","journal-title":"J Psychiatry Neurosci"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291717000514","article-title":"Modulation of error monitoring in obsessive-compulsive disorder by individually tailored symptom provocation","volume":"47","author":"Roh","year":"2017","journal-title":"Psychol Med"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2017.01.001","article-title":"Obsessions and compulsions in the lab: a meta-analysis of procedures to induce symptoms of obsessive-compulsive disorder","volume":"52","author":"De Putter","year":"2017","journal-title":"Clin Psychol Rev"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1989.01810110048007","article-title":"The yale-brown obsessive compulsive scale. I. development, use, and reliability","volume":"46","author":"Goodman","year":"1989","journal-title":"Arch Gen Psychiatry"}],"container-title":["Frontiers in Psychiatry"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fpsyt.2019.00814\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,11,21]],"date-time":"2019-11-21T17:03:22Z","timestamp":1574355802000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fpsyt.2019.00814\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,11]]},"references-count":54,"alternative-id":["10.3389\/fpsyt.2019.00814"],"URL":"https:\/\/doi.org\/10.3389\/fpsyt.2019.00814","relation":{},"ISSN":["1664-0640"],"issn-type":[{"type":"electronic","value":"1664-0640"}],"subject":[],"published":{"date-parts":[[2019,11,11]]},"article-number":"814"}}