{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T02:26:59Z","timestamp":1783132019141,"version":"3.54.6"},"reference-count":67,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,2,5]],"date-time":"2020-02-05T00:00:00Z","timestamp":1580860800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["PI18\/00009"],"award-info":[{"award-number":["PI18\/00009"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychiatry"],"DOI":"10.3389\/fpsyt.2019.01023","type":"journal-article","created":{"date-parts":[[2020,2,19]],"date-time":"2020-02-19T10:33:40Z","timestamp":1582108420000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":7,"title":["A Multicenter Phase II RCT to Compare the Effectiveness of EMDR Versus TAU in Patients With a First-Episode Psychosis and Psychological Trauma: A Protocol Design"],"prefix":"10.3389","volume":"10","author":[{"given":"Alicia","family":"Valiente-G\u00f3mez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuria","family":"Pujol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Moreno-Alc\u00e1zar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joaquim","family":"Radua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eila","family":"Monteagudo-Gimeno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Itxaso","family":"Gardoki-Souto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bridget","family":"Hogg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Jos\u00e9","family":"\u00c1lvarez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gemma","family":"Safont","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter","family":"Lupo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"P\u00e9rez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benedikt L.","family":"Amann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the FEP-EMDR Research Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2020,2,5]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbs130","article-title":"A systematic review and meta-analysis of recovery in schizophrenia","volume":"39","author":"J\u00e4\u00e4skel\u00e4inen","year":"2013","journal-title":"Schizophr Bull"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1159\/000449417","article-title":"Meta-analysis of the risk of subsequent mood episodes in bipolar disorder","volume":"86","author":"Radua","year":"2017","journal-title":"Psychother Psychosom"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.117.205955","article-title":"Trauma and psychotic experiences: transnational data from the World Mental Health survey","volume":"211","author":"McGrath","year":"2017","journal-title":"Br J Psychiatry"},{"key":"B4","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1016\/j.cpr.2016.08.003","article-title":"Trauma and the psychosis spectrum: a review of symptom specificity and explanatory mechanisms","volume":"49","author":"Gibson","year":"2016","journal-title":"Clin Psychol Rev"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbs050","article-title":"Childhood adversities increase the risk of psychosis: a meta-analysis of patient-control, prospective-and cross-sectional cohort studies","volume":"38","author":"Varese","year":"2012","journal-title":"Schizophr Bull"},{"key":"B6","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1111\/bdi.12490","article-title":"Systematic assessment of environmental risk factors for bipolar disorder: an umbrella review of systematic reviews and meta-analyses","volume":"19","author":"Bortolato","year":"2017","journal-title":"Bipolar Disord"},{"key":"B7","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1111\/papt.12159","article-title":"Acceptance and commitment therapy for psychosis and trauma: Improvement in psychiatric symptoms, emotion regulation, and treatment compliance following a brief group intervention","volume":"91","author":"Spidel","year":"2018","journal-title":"Psychology and Psychotherapy: Theory, Research and Practice"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1097\/NMD.0b013e31820c751c","article-title":"Prevalence and clinical impact of childhood trauma in patients with severe mental disorders","volume":"199","author":"\u00c1lvarez","year":"2011","journal-title":"J Nerv Ment Dis"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbx161","article-title":"Childhood trauma is associated with severity of hallucinations and delusions in psychotic disorders: a systematic review and meta-analysis","volume":"44","author":"Bailey","year":"2018","journal-title":"Schizophr Bull"},{"key":"B10","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1007\/s00127-006-0127-2","article-title":"The subjective consequences of suffering a first episode psychosis: trauma and suicide behaviour","volume":"42","author":"Tarrier","year":"2007","journal-title":"Soc Psychiatry Psychiatr Epidemiol"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbp148","article-title":"How prevalent are anxiety disorders in schizophrenia? A meta-analysis and critical review on a significant association","volume":"37","author":"Achim","year":"2011","journal-title":"Schizophr Bull"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1016\/j.comppsych.2007.12.003","article-title":"The prevalence and correlates of trauma-related symptoms in schizophrenia spectrum disorder","volume":"49","author":"Lysaker","year":"2008","journal-title":"Compr Psychiatry"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2009.10.025","article-title":"The trauma of psychosis: posttraumatic stress disorder and recent onset psychosis","volume":"116","author":"Mueser","year":"2010","journal-title":"Schizophr Res"},{"key":"B14","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1023\/A:1024794232175","article-title":"PTSD and comorbid psychotic disorder: Comparison with veterans diagnosed with PTSD or psychotic disorder","volume":"12","author":"Sautter","year":"1999","journal-title":"J Trauma Stress"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1097\/00005053-199105000-00002","article-title":"Posttraumatic stress disorder following recent-onset psychosis: an unrecognized postpsychotic syndrome","volume":"179","author":"McGorry","year":"1991","journal-title":"J Nerv Ment Dis"},{"key":"B16","doi-asserted-by":"publisher","first-page":"105","DOI":"10.3371\/csrp.ABOU.123015","article-title":"Post - traumatic stress disorder in first episode psychosis: prevalence and related factors","volume":"12","author":"Abdelghaffar","year":"2016","journal-title":"Clin Schizophr Relat Psychoses"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1177\/0004867411430877","article-title":"Childhood trauma increases the risk of post-traumatic stress disorder in response to first-episode psychosis","volume":"46","author":"Bendall","year":"2012","journal-title":"Aust N Z J Psychiatry"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1111\/papt.12035","article-title":"Trauma in relation to psychosis and hospital experiences: the role of past trauma and attachment","volume":"88","author":"Berry","year":"2015","journal-title":"Psychol Psychother Theory Res Pract"},{"key":"B19","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1097\/NMD.0b013e31819273a8","article-title":"Predictors of PTSD symptoms in response to psychosis and psychiatric admission","volume":"197","author":"Beattie","year":"2009","journal-title":"J Nerv Ment Dis"},{"key":"B20","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1016\/j.schres.2008.01.024","article-title":"Predictors and profiles of treatment non-adherence and engagement in services problems in early psychosis","volume":"102","author":"Lecomte","year":"2008","journal-title":"Schizophr Res"},{"key":"B21","doi-asserted-by":"publisher","first-page":"S3","DOI":"10.1016\/j.jad.2012.02.029","article-title":"Pharmacotherapy challenges in patients with first-episode psychosis","volume":"138","author":"Abdel-Baki","year":"2012","journal-title":"J Affect Disord"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1002\/jclp.10068","article-title":"Eye movement desensitization and reprocessing (EMDR): information processing in the treatment of trauma","volume":"58","author":"Shapiro","year":"2002","journal-title":"Psychother Pract"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2017.01668","article-title":"EMDR beyond PTSD: a systematic literature review","volume":"8","author":"Valiente-G\u00f3mez","year":"2017","journal-title":"Front Psychol"},{"key":"B24","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1097\/01.pra.0000442936.23457.5b","article-title":"Inclusion and exclusion criteria in randomized controlled trials of psychotherapy for PTSD","volume":"20","author":"Ronconi","year":"2014","journal-title":"J Psychiatr Pract"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291716001094","article-title":"Prolonged exposure and EMDR for PTSD v. a PTSD waiting-list condition: effects on symptoms of psychosis, depression and social functioning in patients with chronic psychotic disorders","volume":"46","author":"de Bont","year":"2016","journal-title":"Psychol Med"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2014.05.012","article-title":"Eye movement desensitization and reprocessing therapy in subsyndromal bipolar patients with a history of traumatic events: A randomized, controlled pilot-study","volume":"219","author":"Novo","year":"2014","journal-title":"Psychiatry Res"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.116.185579","article-title":"Effectiveness of trauma-focused treatment for patients with psychosis with and without the dissociative subtype of post-traumatic stress disorder","volume":"209","author":"Van Minnen","year":"2016","journal-title":"Br J Psychiatry"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1080\/20008198.2018.1565032","article-title":"Health\u2013economic benefits of treating trauma in psychosis","volume":"10","author":"de Bont","year":"2019","journal-title":"Eur J Psychotraumatol"},{"key":"B29","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1037\/0022-006X.66.1.7","article-title":"Defining empirically supported therapies","volume":"66","author":"Chambless","year":"1998","journal-title":"J Consult Clin Psychol"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1002\/sim.6576","article-title":"Exact optimum coin bias in Efron\u2019s randomization procedure","volume":"34","author":"Antognini","year":"2015","journal-title":"Stat Med"},{"key":"B31","article-title":"International Conference on Harmonisation; Guidance on Statistical Principles for Clinical Trials. Guideline E9. Statistical principles for clinical trials","volume-title":"Fed. Regist.","year":"1998"},{"key":"B32","unstructured":"Implementation of E9 Statistical Principles for Clinical Trials1998"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291711002522","article-title":"Cognitive behaviour therapy and supportive therapy for bipolar disorders: relapse rates for treatment period and 2-year follow-up","volume":"42","author":"Meyer","year":"2012","journal-title":"Psychol Med"},{"key":"B34","first-page":"1668","author":"Shapiro","year":"2001"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1891\/1933-3196.3.3.141","article-title":"EMDR treatment of recent trauma","volume":"3","author":"Shapiro","year":"2009","journal-title":"J EMDR Pract Res"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.151.8.1132","article-title":"Initial reliability and validity of a new retrospective measure of child abuse and neglect","volume":"151","author":"Bernstein","year":"1994","journal-title":"Am J Psychiatry"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1177\/0886260512468240","article-title":"Initial validation of the spanish childhood trauma questionnaire-short form: factor structure, reliability and association with parenting","volume":"28","author":"Hernandez","year":"2013","journal-title":"J Interpers Violence"},{"key":"B38","doi-asserted-by":"publisher","first-page":"25","DOI":"10.5093\/cl2012a4","article-title":"Posttraumatic stress assessment: introducing the global assessment of posttraumatic stress questionnaire","volume":"23","author":"Crespo","year":"2012","journal-title":"Cl\u00edn. y Salud"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3999(67)90010-4","article-title":"The social readjustment rating scale","volume":"11","author":"Holmes","year":"1967","journal-title":"J Psychosom Res"},{"key":"B40","first-page":"7","article-title":"La valoraci\u00f3n de sucesos vitales: adaptaci\u00f3n espa\u00f1ola de la escala de Holmes y Rahe","volume":"4","author":"Gonz\u00e1lez de Rivera","year":"1983","journal-title":"Psiquis (Mexico)"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1111\/psyg.12024","article-title":"Stressful life events and neuroticism as predictors of late-life versus early-life depression","volume":"13","author":"Weber","year":"2013","journal-title":"Psychogeriatrics"},{"key":"B42","volume-title":"The Impact of Event Scale-Revised","author":"Weiss","year":"1997"},{"key":"B43","first-page":"581","article-title":"Propiedades Psycometricas de la Version Espa\u00f1ola de la Escala Revisionada de Impacto del Estresor (EIE-R)","volume":"27","author":"B\u00e1guena","year":"2001","journal-title":"Anal y Modif Conduct"},{"key":"B44","first-page":"69","article-title":"Dissociative experiences: a measurement scale","volume":"70","author":"Icaran","year":"1996","journal-title":"Exp Disociativas Una Escala Med"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1097\/00005053-199611000-00006","article-title":"The development and psychometric characteristics of the somatoform dissociation questionnaire (SDQ-20)","volume":"184","author":"Nijenhuis","year":"1996","journal-title":"J Nerv Ment Dis"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.7334\/psicothema2016.346","article-title":"Validity and reliability of the Spanish version of the Somatoform Dissociation Questionnaire (SDQ-20)","volume":"29","author":"Gonz\u00e1lez-v\u00e1zquez","year":"2017","journal-title":"Psicothema"},{"key":"B47","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1037\/t18597-000","article-title":"The mini-international neuropsychiatric interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10","volume":"59","author":"Sheehan","year":"1998","journal-title":"J Clin Psychiatry"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1016\/S0924-9338(99)80240-5","article-title":"A Spanish validation study of the mini international neuropsychiatric interview","volume":"13","author":"Bobes","year":"1998","journal-title":"Eur Psychiatry"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1961.01710120031004","article-title":"An inventory for measuring depression","volume":"4","author":"Beck","year":"1961","journal-title":"Arch Gen Psychiatry"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1207\/s15327752jpa6703_13","article-title":"Comparison of Beck depression inventories -IA and -II in psychiatric outpatients","volume":"67","author":"Beck","year":"1996","journal-title":"J Pers Assess"},{"key":"B51","first-page":"59","article-title":"Fiabilidad y validez de la versi\u00f3n espa\u00f1ola del Inventario para la Depresi\u00f3n de Beck de 1978 en pacientes con trastornos psicol\u00f3gicos","volume":"10","author":"V\u00e1zquez","year":"1999","journal-title":"Cl\u00edn. y Salud"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.133.5.429","article-title":"A rating scale for mania: reliability, validity and sensitivity","volume":"133","author":"Young","year":"1978","journal-title":"Br J Psychiatry"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-7753(02)73419-2","article-title":"Spanish version of a scale for the assessment of mania: validity and reliability of the young mania rating scale","volume":"119","author":"Colom","year":"2002","journal-title":"Med Clin (Barc)"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/13.2.261","article-title":"The positive and negative syndrome scale for schizophrenia","volume":"13","author":"Kay","year":"1987","journal-title":"Schizophr Bull"},{"key":"B55","article-title":"Validation of positive and negative symptom scale (PANSS) in a sample of Spanish schizophrenic patients","volume":"22","author":"Peralta","year":"1994","journal-title":"Actas Luso Esp Neurol Psiquiatr Cienc Afines"},{"key":"B56","first-page":"1","article-title":"Rater training for a multi-site, international clinical trial: what mood symptoms may be most difficult to rate","volume":"44","author":"Sajatovic","year":"2011","journal-title":"Psychopharmacol Bull"},{"key":"B57","article-title":"Banco de instrumentos b\u00e1sicos para la pr\u00e1ctica de la psiquiatr\u00eda cl\u00ednica","author":"Garc\u00eda-Portilla","year":"2011"},{"key":"B58","unstructured":"EQ-5D Instruments2019"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-018-1877-5","article-title":"Validity of the EQ\u20135D\u20135L and reference norms for the Spanish population","volume":"27","author":"Hernandez","year":"2018","journal-title":"Qual Life Res"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1016\/S0920-9964(03)00189-0","article-title":"A new instrument for measuring insight: the beck cognitive insight scale","volume":"68","author":"Beck","year":"2004","journal-title":"Schizophr Res"},{"key":"B61","first-page":"2","article-title":"Spanish adaptation of the beck cognitive insight scale (BCIS) for schizophrenia","volume":"40","author":"Guti\u00e9rrez-Zotes","year":"2012","journal-title":"Actas Esp Psiquiatr"},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2012.02.008","article-title":"DAI-10 is as good as DAI-30 in schizophrenia","volume":"22","author":"Nielsen","year":"2012","journal-title":"Eur Neuropsychopharmacol"},{"key":"B63","article-title":"Assessment of drug attitudes in patients with schizophrenia: psychometric properties of the DAI Spanish version","volume":"32","author":"Robles Garc\u00eda","year":"2004","journal-title":"Actas Esp Psiquiatr"},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.1002\/wps.20446","article-title":"Improving outcomes of first-episode psychosis: an overview","volume":"16","author":"Fusar-Poli","year":"2017","journal-title":"World Psychiatry"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2018.0623","article-title":"Comparison of early intervention services vs treatment as usual for early-phase psychosis: a systematic review, meta-analysis, and meta-regression","volume":"75","author":"Correll","year":"2018","journal-title":"JAMA Psychiatry"},{"key":"B66","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1093\/schbul\/sbv172","article-title":"Trauma-focused treatment in PTSD patients with psychosis: symptom exacerbation, adverse events, and revictimization","volume":"42","author":"Van Den Berg","year":"2016"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbtep.2011.09.011","article-title":"Treating trauma in psychosis with EMDR: a pilot study","volume":"43","author":"Van Den Berg","year":"2012","journal-title":"J Behav Ther Exp Psychiatry"}],"updated-by":[{"DOI":"10.3389\/fpsyt.2020.00283","type":"corrigendum","label":"Corrigendum","source":"publisher","updated":{"date-parts":[[2020,4,14]],"date-time":"2020-04-14T00:00:00Z","timestamp":1586822400000}}],"container-title":["Frontiers in Psychiatry"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fpsyt.2019.01023\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,2,19]],"date-time":"2020-02-19T10:33:46Z","timestamp":1582108426000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fpsyt.2019.01023\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,5]]},"references-count":67,"alternative-id":["10.3389\/fpsyt.2019.01023"],"URL":"https:\/\/doi.org\/10.3389\/fpsyt.2019.01023","relation":{"corrigendum":[{"id-type":"doi","id":"10.3389\/fpsyt.2020.00283","asserted-by":"object"}]},"ISSN":["1664-0640"],"issn-type":[{"value":"1664-0640","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,5]]},"article-number":"1023"}}